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Search Results: 1 - 10 of 2232 matches for " Joanna Dmowska-Chalaba "
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Immune system as a new therapeutic target for antibiotics  [PDF]
Brygida Kwiatkowska, Maria Maslinska, Malgorzata Przygodzka, Joanna Dmowska-Chalaba, Justyna Dabrowska, Katarzyna Sikorska-Siudek
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.44A013

Since the discovery of penicillin by Fleming in 1928, the knowledge of the antibiotics’ spectrum and mechanism of action has been steadily increasing. Antibiotics became an effective tool in the fight against many pathogens, changing the prognosis of outcome for many serious diseases. It is already known that antibiotics not only have the antibacterial activity, but many of theme.g. macrolides, sulphonamides and tetracyclineshave immunomodulating effect, affecting functions of lymphocytes, macrophages and costimulatory molecules, macrophage migration and phagocytosis, as well as proinflammatory cytokine secretion. The expanding knowledge of the effects of antibiotics on the immune system has brought with it new applications of antibiotics in organ transplantation, invasive cardiology and treatment of autoimmune diseases such as rheumatoid arthritis or asthma.

Novel ferulic acid esterases from Bifidobacterium sp. produced on selected synthetic and natural carbon sources
Dominik Szwajgier,Anna Dmowska
Acta Scientiarum Polonorum : Technologia Alimentaria , 2010,
Abstract: Background. Ferulic acid esterases (or feruloyl esterases), a common group of hydrolases are very well distributed in the plant kongdom. The fungal feruloyl esterases were very extensively studied whereas probiotic lactic acid bacteria as the source of this enzyme were generally omitted. Free phenolic acids – strong antioxidants can be released from the dietary fiber by the action of intestinal lactic acid bacteria. The aim of this study was to examine the three probiotic Bifidobacterium strains to produce extracellular FAE on different synthetic and natural carbon sources. Material and methods. Studies were carried out using Bifidibacteriumstrains (B. animalis Bi30, B. catenulatum KD 14 and B. longum KN 29). The strains were cultivated using minimal growth media containing selected natural and synthetic carbon sources: German wheat bran, rye bran, barley spent grain, isolated larchwood arabinogalactan, apple pectin, corn pectin, methyl esters of phenolic acids. The production of extracellular feruloyl esterase was estimated using the post cultivation supernatants and methyl ferulate. The concentration of ferulic acid released from the ester was determined using HPLC with DAD detection. Results. The most efficient bacterial strain for FAE production was B. animalis cultivated in the presence of methyl p-coumarate and methyl ferulate as the main carbon sources (14.95 nmol·ml-1·min-1 and 4.38 nmol·ml-1·min-1, respectively). In the case of each FAE, the highest activity was obtained at 37oC (pH 6.3) in Theorell/Steinhagen buffer (B. animalis Bi30) or in Tris/HCl buffer (B. catenulatum KD14 and B. longum KN29). Taking under consideration all results, it should be noticed that the highest feruloyl esterase activities were obtained using synthetic methyl esters of phenolic acids. Conclusions. The presented resultsbroaden the knowledgeabout the production of the feruloyl esterase by probiotic bacteria. Although the enzyme is only accessory during the hydrolysis of food components during intestinal digestion, some conclusions on the role of lactic acid bacteria in the release of food antioxidants phenolic acids can be established.
Participation and Activity Rates: Monitoring Exposure Potential for Native Americans and Others in the United States  [PDF]
Joanna Burger
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.28116
Abstract: Managers and regulators are concerned about potential human health effects from exposure on lands contaminated by chemicals and radionuclides. Determining target cleanup levels is partly dependent upon future land use, and potential exposure from human use. This paper provides data from surveys of activity patterns of people attending festivals in four states, located in the vicinity of Department of Energy facilities. There were significant differences in both participation rates, and activity rates as a function of both location and ethnicity that can be used by managers to track exposure, land use, and preferred activities on natural lands. In general, 1) a higher percent of Native Americans engaged in consumptive activities than others, 2) a higher percent of Caucasians engaged in some non-consumptive activities than Native Americans, 3) a higher percentage of Native Americans engaged in activities on sacred grounds, 4) activity rates were generally higher for Native Americans for consumptive activities and religious/cultural than for Caucasians, 5) fishing rates were higher than other consumptive activities, and camping/hiking were higher than other non-con- sumptive activities, and 6) hunting rates were higher in subjects from Idaho than elsewhere. Baseline human use is critical for monitoring potential exposure, and provides the basis for monitoring, risk assessment and future land use, and these data can be used by managers for assessment and management. Tracking changes over time will reflect changing recreational, subsistence, and cultural/religious trends that relate to land use, public perceptions, and exposure.
In-Arrears Interest Rate Derivatives under the 3/2 Model  [PDF]
Joanna Goard
Modern Economy (ME) , 2015, DOI: 10.4236/me.2015.66067
Abstract: Lie symmetry methods are used to find a closed form solution for in-arrears swaps under the 3/2 model \"\". As well, approximate solutions are found for short-tenor in-arrears caplets and floorlets under the same interest rate model. Comparisons are made of the approximate option values with those obtained with a computationally-intensive numerical scheme. The approximate pricing is found to be substantially fast and easy to implement, while the relative errors with respect to the “true” prices are very small.
Surface Layer Properties after Successive EDM or EDA and Then Superficial Roto-Peen Machining
Agnieszka Dmowska,Bogdan Nowicki,Anna Podolak-Lejtas
Advances in Tribology , 2012, DOI: 10.1155/2012/723919
Abstract: The paper presents the results of the influence of basic electrical discharge machining EDM parameters and electrical discharge alloying EDA parameters on surface layer properties and on selected performance properties of machine parts after such machining but also the influence of superficial cold-work treatment applied after the EDM of EDA on modification of these properties. The investigations included texture of the surface, metallographic microstructure, microhardness distribution, fatigue strength, and resistance to abrasive wear. It was proved that the application of the roto-peen after the EDM and the EDA resulted in lowering roughness height up to 70%, the elevation of surface layer microhardness by 300–700?μHV, and wear resistance uplifting by 300%. 1. Basics of the EDM, the EDA, and the Roto-Peen Machining Electrical discharge machining (EDM) is widely used in manufacturing of accurate parts of complex shapes, built of hard and impossible-to-cut or hard-to-cut materials [1, 2]. Electrical discharge alloying (EDA) is applied for generation of surface layer (SL) with volume share of up to several dozens percent of alloy elements. Such layers are up to 200?μm thick and they can be useful in wear-resistant tooling, erosion-resistant equipment, and so forth [3, 4]. The EDM and EDA processes are defined by spark discharge and the associated physical processes. Such processes take place in the presence of dielectric—in the EDM usually kerosene or water is employed and the spark discharges release energy of several millijoules while the EDA process is carried out in air, neutral gas, oil or kerosene, and the spark discharge energy is much higher and discharge duration is longer. Spark discharge generate much heat on small surface of the anode and the cathode. Power density inside the spark channel has been estimated as 1017?W/m2 and local temperature could be raised up to 20?000 Kelvin degree [1, 3, 5, 6]. The eruption of molten material is critically important for material removal in the EDM process. Spark discharge results in local material loss, the craters and flashes are formed (Figure 1), and they are covered with the thin film of previously molten and then solidified metal [1, 7]. The volume of material removed from a single crater is ?(μm3). Figure 1: The SEM image of an individual electric discharge on the machined surface, its 3D view, and its profilogram ( U = 80?V, I = 48?A, Ti = 400? μs). Due to repeatedly occurring spark discharges, a surface layer of specific isotropic roughness is being created and this layer shows different
A Conceptual Framework Evaluating Ecological Footprints and Monitoring Renewable Energy: Wind, Solar, Hydro, and Geothermal  [PDF]
Joanna Burger, Michael Gochfeld
Energy and Power Engineering (EPE) , 2012, DOI: 10.4236/epe.2012.44040
Abstract: With worldwide increases in energy consumption, and the need to increase reliance on renewable energy, we must examine ecological footprints of each energy source, as well as its carbon emissions. Renewable energy sources (wind, solar, hydro, geothermal) are given as the best examples of “green” energy sources with low carbon emissions. We provide a conceptual model for examining the ecological footprint of energy sources, and suggest that each resource needs continued monitoring to protect the environment, and ultimately human health. The effects and consequences of ecological footprint need to be considered in terms of four-compartments: underground (here defined as geoshed), surface, airshed, and atmosphere. We propose a set of measurement endpoints (metrics may vary), in addition to CO2 footprint, that are essential to evaluate the ecological and human health consequences of different energy types. These include traditional media monitoring (air, water, soil), as well as ecological footprints. Monitoring human perceptions of energy sources is also important for energy policy, which evolves with changes in population density, technologies, and economic consequences. While some assessment endpoints are specific to some energy sectors, others can provide crosscutting information allowing the public, communities and governments to make decisions about energy policy and sustainability.
Consumption of Alzheimer disease protective nutrients in diets of polish elderly divided into different nutritional status (MNA)  [PDF]
Joanna Wyka, Jadwiga Biernat
Health (Health) , 2012, DOI: 10.4236/health.2012.429117
Abstract: Many abnormalities can be observed in the nutrition of elderly people which, as a consequence, lead to occurrence or progression of many already existing diet-dependent diseases. The aim of this work was assessment of nutrients consumption, important for prevention and treatment of diet-dependent diseases and potentially neuropsychological diseases, including Alzheimer disease. The intake of antioxidant vitamins, group B vitamins and polyunsaturated fatty acids in food ratios was assessed among 1001 people over 60 years of age, from Wroclaw and nearby areas, SW Poland. Selected parameters of lipid and carbohydrate metabolism were determined in the blood of surveyed people. A deficit intake of all nutrients was demonstrated in groups distinguished by MNA form. Moreover, it was demonstrated that statistically significant, the lowest amounts of vitamin A, E, C, B6, B12, folates, and many other polyunsaturated fatty acids were consumed by women at risk of malnutrition in comparison with women with an adequate nutritional status. Statistically significant lower biochemical parameters, such as TC, LDL TG and glucose were also demonstrated in the group of women at risk of malnutrition than in the group of women with an adequate nutritional status. Control and supervision of the elderly persons’ nutritional intake constitutes the basis of the assessment of risk of deficiency of particular nutritional components occurrence and negative health effects deriving from it. Poor nutrition of seniors along with longer life, from demographic point of view, induces to search for new efficient health-oriented strategies.
Knowledge and Perceptions of Energy Alternatives, Carbon and Spatial Footprints, and Future Energy Preferences within a University Community in Northeastern US  [PDF]
Joanna Burger, Michael Gochfeld
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54033

Our overall research aim was to examine whether people distinguished between the spatial footprint and carbon footprint of different energy sources, and whether their overall “worry” about energy types was related to future developed of these types. We surveyed 451 people within a university community regarding knowledge about different energy sources with regard to renewability and spatial and carbon footprints and attitudes about which energy type(s) should be developed further. Findings were: 1) Gas, oil and coal were rated as the least renewable, and wind, solar and hydro as the most renewable; 2) Oil and coal were rated as having the largest carbon footprint, while wind, solar and tidal were rated the lowest; 3) There were smaller differences in ratings for spatial footprints, probably reflecting unfamiliarity with the concept, although oil and gas were rated the highest; 4) Energy sources viewed as renewable were favored for future development compared with non-renewable energy sources, and coal and oil were rated the lowest; 5) Worry-free sources such as solar were favored; and 6) There were some age-related differences, but they were small, and there were no gender-related differences. Overall, subjects knew more about carbon footprints than spatial footprints, generally correctly identified renewable and non-renewable sources, and wanted future energy development for energy sources which were less worried about (e.g. solar, wind). These perceptions require in-depth examination in a large sample from different areas of the country.

Portrayal of Teachers in Popular Media: Pushing the Frontier of Collaboration with Media Business in Pedagogy and Technology  [PDF]
Orest Cap, Joanna Black
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.25028

This presentation is based on a unique Summer Institute at the University of Manitoba, Canada in which the presenters examined the relationship between pedagogy and the popular mass media from ([6] Butler, 2000; [12] Maruri, 2012) and beyond [11] Dalton (2010). The image of the tea- cher provides thematic explorations of school culture, pedagogy, human rights, equality, race, gender, bullying, poverty, stereotyping, and power relations [7] Bulman (2005). The authors of the paper describe a case study which was carried out in a Post Baccalaureate Diploma in Education and Master of Education program at the Faculty of Education over a two-week period in August of 2013 with 24 pre-service public school teachers and technical college instructors.

Creative Digital Arts Education: Exploring Art, Human Ecology, and New Media Education through the Lens of Human Rights  [PDF]
Joanna Black, Orest Cap
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.47034
The development of an innovative pedagogical model based on case study research about human rights education regarding discourses of power and food in relation to visual arts education and human ecology education will be examined. The authors outline two ongoing studies about “digiART” and Human Rights: New Media, Art, and Human Ecology Integrated Projects. These projects have been held at the University of Manitoba, Canada for pre-service teachers training to be secondary level educators: the research has been ongoing since 2013. As a result of the studies, meaningful curricula and innovative pedagogy have been developed using contemporary technologies. Key to the studies is not only the incorporation of creative teaching and learning about digital technologies at the higher education level but also integrating human rights issues into curricula. The authors’ approaches to teaching human rights issues to pre-service teachers are described in which they incorporate creative technologies to foster an innovative pedagogical model, and develop productive learning using digital technologies. Student’s new media practices from preproduction to postproduction are delineated and benefits from using this approach are discussed.
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