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Search Results: 1 - 10 of 51276 matches for " Jin-Hee Lee "
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Early experience of the compression anastomosis ring (CARTM 27) in left-sided colon resection
Jung-Yeon Lee,Jin-Hee Woo,Hong-Jo Choi,Ki-Jae Park
World Journal of Gastroenterology , 2011, DOI: 10.3748/wjg.v17.i43.4787
Abstract: AIM: To evaluate clinical validity of the compression anastomosis ring (CAR 27) anastomosis in left-sided colonic resection. METHODS: A non-randomized prospective data collection was performed for patients undergoing an elective left-sided colon resection, followed by an anastomosis using the CAR 27 between November 2009 and January 2011. Eligibility criteria of the use of the CAR 27 were anastomoses between the colon and at or above the intraperitoneal rectum. The primary short-term clinical endpoint, rate of anastomotic leakage, and other clinical outcomes, including intra- and postoperative complications, length of operation time and hospital stay, and the ring elimination time were evaluated. RESULTS: A total of 79 patients (male, 43; median age, 64 years) underwent an elective left-sided colon resection, followed by an anastomosis using the CAR 27. Colectomy was performed laparoscopically in 70 patients, in whom two patients converted to open procedure (2.9%). There was no surgical mortality. As an intraoperative complication, total disruption of the anastomosis occurred by premature enforced tension on the proximal segment of the anastomosis in one patient. The ring was removed and another new CAR 27 anastomosis was constructed. One patient with sigmoid colon cancer showed postoperative anastomotic leakage after 6 d postoperatively and temporary diverting ileostomy was performed. Exact date of expulsion of the ring could not be recorded because most patients were not aware that the ring had been expelled. No patients manifested clinical symptoms of anastomotic stricture. CONCLUSION: Short-term evaluation of the CAR 27 anastomosis in elective left colectomy suggested it to be a safe and efficacious alternative to the standard hand-sewn or stapling technique.
Characteristics of HIV seroprevalence of visitors to public health centers under the national HIV surveillance system in Korea: cross sectional study
Mee-Kyung Kee, Jin-Hee Lee, Chaeshin Chu, Eun-Ju Lee, Sung-Soon Kim
BMC Public Health , 2009, DOI: 10.1186/1471-2458-9-123
Abstract: We used HIV-testing data from 246 PHCs in 2005 through the Health Care Information System. The number of test taker was calculated using the code distinguished by the residential identification number. The subjects were classified into four groups by reason for testing; General group, HIV infection suspected group (HIV ISG), HIV test recommended group (HIV TRG), and sexually transmitted infection (STI) risk group.People living with HIV/AIDS were 149 (124 male and 25 female) among 280,456 individuals tested at PHCs. HIV seroprevalence was 5.3 per 10,000 individuals. Overall, the male revealed significantly higher seroprevalence than the female (adjusted Odds Ratio (adj. OR): 6.2; CI 3.8–10.2). Individuals aged 30–39 years (adj. OR: 2.6; CI 1.7–4.0), and 40–49 years (adj. OR: 3.8; CI 2.4–6.0) had higher seroprevalence than 20–29 years. Seroprevalence of HIV ISG (voluntary test takers and cases referred by doctors) was significantly higher than those of others. Foreigners showed higher seroprevalence than native Koreans (adj. OR: 3.8; CI 2.2–6.4). HIV ISG (adj. OR: 4.9; CI 3.2–7.5), and HIV TRG (adj. OR: 2.6; CI 1.3–5.4) had higher seroprevalence than General group.A question on the efficiency of current mandatory test is raised because the seroprevalence of mandatory test takers was low. However, HIV ISG included voluntary test takers was high in our result. Therefore, we suggest that Korea needs to develop a method encouraging more people to take voluntary tests at PHCs, also to expand the anonymous testing centers and Voluntary Counselling and Testing Program (VCT) for general population to easily access to HIV testing.The first case of acquired immunodeficiency syndrome (AIDS) in Korea was a foreign resident, and the first human immunodeficiency virus (HIV)-infected Korean contracted the virus during overseas travel in 1985 [1]. This stimulated a national preventative system for this emerging infection in Korea, which became prevalent in the United States and Europ
Estimation of hospital-based HIV seroprevalence as a nationwide scale by novel method; 2002-2008 in Korea
Jin-Hee Lee, Kee-Jong Hong, Jin-Sook Wang, Sung Kim, Mee-Kyung Kee
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-739
Abstract: Between 2002 and 2008, data included HIV tests on insurance claims in hospitals and the proportion of computerized insurance claims from the Health Insurance Review and Assessment Services. The number of HIV tests from the survey in the External Quality Assurance Scheme for hospital laboratories was collected to calculate the insurance claim proportion. HIV seroprevalence was estimated using data of tested individuals, including infected individuals. Statistical analysis was confirmed with the 95% confidence interval. Statistical significance was defined at p-values < 0.05.The number of HIV tests in hospitals increased from 2.7 million in 2002 to 5.0 million in 2008. The trend of HIV seroprevalence was decrease (1.5-1.3 per 10,000 individuals, P < 0.0028), except in 2002. The number of women tested was greater than men, and the proportion increased in older individuals and in small towns. Men had a higher annual HIV seroprevalence than women (P < 0.0001). The annual seroprevalence decreased in men (P = 0.0037), but was stable in women. The seroprevalence in the 30-39 year age group demonstrated higher than other age groups except 2008.The nationwide hospital-based number of HIV tests and seroprevalence were estimated using a new method and seroprevalence trends were identified. This information will facilitate improvement in national HIV prevention strategies.UNAIDS has provided basic information about the HIV/AIDS epidemic by predicting the number of HIV-infected individuals in each country, in addition to the worldwide data [1,2]. The AIDS Epidemic software (EPIMODEL) was developed by the WHO in the late 1980 s to estimate the past and current HIV prevalence, and to make short-term projections of AIDS cases and deaths in areas where AIDS case reporting was largely incomplete and unreliable [3,4]. UNAIDS reported that there are 33.4 million people living with HIV/AIDS (PLWHA) worldwide, and 4.7 million HIV-positive individuals were alive in Asia in 2008 [5]. There
Improvement in survival among HIV-infected individuals in the Republic of Korea: Need for an early HIV diagnosis
Mee-Kyung Kee, Jin-Hee Lee, Eun-Jin Kim, Jiae Lee, Jeong-Gu Nam, Byung-Hee Yoo, Sung Kim
BMC Infectious Diseases , 2009, DOI: 10.1186/1471-2334-9-128
Abstract: A total of 5,323 HIV-infected individuals were registered with the government and followed until the end of 2007. Survival following HIV diagnosis was estimated based on epidemiological characteristics. We examined 3,369 individuals with available initial CD4+ T-cell counts within 6 months of HIV diagnosis to estimate survival based on immune status at diagnosis. The association between epidemiological variables and survival times was analyzed with univariate and multivariate Cox's proportional hazards model.Individuals died during the study period (n = 980), and 45% of the individuals died within 6 months of HIV diagnosis. The median survival following HIV diagnosis was 16.7 years. Survival were longer in women, in younger persons, in individuals diagnosed at blood centers, and in individuals diagnosed later in the study period. Survival were shortest in individuals with CD4+ T-cell counts <200 cells/mm3 at HIV diagnosis. These results suggest that early HIV diagnosis in Korea is imperative to increase survival and to promote the quality of life for HIV-infected individuals with governmental support.The median survival time of HIV-infected individuals following HIV diagnosis was 16.7 years in Korea. The survival was significantly lower in individuals with CD4+ T-cell counts <200 cells/mm3 at HIV diagnosis and higher by introduction of drugs and development of therapy.There are nearly 60 million individuals infected with Human Immunodeficiency Virus (HIV) since the early 1980s, and at least 25 million HIV-infected individuals have died of Acquired Immunodeficiency Syndrome (AIDS) since the beginning of the epidemic [1]. AIDS has decreased life expectancies by 20 years, and the high rates of HIV infection in adolescents and women of reproductive age have resulted in community destruction, family dissolution, and economic loss in many sub-Saharan African countries. AIDS prevention program has been actively performed, and there has been significant ongoing research foc
High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis
Chang-Hwan Yeom, Gunsup Lee, Jin-Hee Park, Jaelim Yu, Seyeon Park, Sang-Yeop Yi, Hye Lee, Young Hong, Joosung Yang, Sukchan Lee
Journal of Translational Medicine , 2009, DOI: 10.1186/1479-5876-7-70
Abstract: Despite advances in medical science, both the number of cancer patients and the death rate due to cancer is increasing. Although new approaches and new carcinostatic agents have been developed, their effects on cancer patients are not sufficient [1]. Since Klenner and colleagues applied vitamin C (ascorbic acid) to cure cancer patients in 1949, cell experiments, model animal experiments and clinical trials have been carried out [2,3]. Linus Pauling and Ewan Cameron reported that the administration of high dose concentrations of ascorbic acid (1.7 × 10-4 mol) to cancer patients in the terminal stage improved the quality of life and extended their lives [4]. Although there are experimental results supporting the carcinostatic effects of ascorbic acid and its use as a therapeutic agent to prevent the growth of cancer cells, there is still controversy over the effects of ascorbic acid. According to the work done by Levin's group [5,6], ascorbic acid has definite effect as an antitumor agent when administrated at a high dose concentration. They reported that high dose concentrations of ascorbic acid, provided intravenously, work as a pro-oxidant therapeutic agent in cancer by generating ascorbate radicals and hydrogen peroxide in extracellular fluid in vivo. In addition, clinical case reports (from kidney cancer and bladder tumors) strongly indicate that high dose concentration ascorbic acid therapy in cancer treatment should be reassessed. These studies were confirmed by histopathologic review and examined in accordance with National Cancer Institute (NCI) Best Case Series guidelines [7].Ascorbic acid mediated direct cytotoxicity effects on cancer cells by hydrogen peroxide have been numerously reviewed [8,9] but in some cases the concentration of ascorbic acid radicals and hydrogen peroxide have not been sufficiently induced tumor cell death [6]. Therefore other action mechanism of ascorbic acid as an anticancer drug has been investigated. The one possibility of ascorb
Angiosarcoma of the Retroperitoneum: Report on a Patient Treated with Sunitinib
Changhoon Yoo,Jeong-Eun Kim,Shin-Kyo Yoon,Song Cheol Kim,Jin-Hee Ahn,Tae Won Kim,Cheolwon Suh,Jae-Lyun Lee
Sarcoma , 2009, DOI: 10.1155/2009/360875
Abstract: A 52 year-old woman presented with an incidentally detected retroperitoneal angiosarcoma and multiple hepatic metastases. After chemotherapy with weekly paclitaxel and doxorubicin, angiosarcoma had progressed rapidly. Because few chemotherapeutic options were available for her, sunitinib (37.5 mg/day, daily) as a salvage regimen was administered. Although sunitinib was interrupted after two weeks due to hematologic abnormalities, some metastatic nodules were regressed. Therefore, sunitinib was recommenced at a reduced dose (25 mg/day, daily). Serial computed tomography scans showed variable response in each tumor, however, sunitinib at least delayed tumor progression, compared to previous chemotherapy. With this case report, we suggest sunitinib may be effective against angiosarcomas. When sunitinib is administered to patients with angiosarcomas, hematologic abnormalities should be monitored frequently as severe hematologic toxicity may be caused either by sunitinib per se or angiosarcoma.
Increasing late diagnosis in HIV infection in South Korea: 2000-2007
Jin-Hee Lee, Gab Kim, Byeong-Sun Choi, Kee-Jong Hong, Mi-Kyung Heo, Sung Kim, Mee-Kyung Kee
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-411
Abstract: Data from 2,299 HIV-infected individuals with initial CD4+ T-cell counts measured within 6 months of HIV diagnosis and reason for HIV testing were recorded and measured from 2000 to 2007. Data were selected from the database of the Korea Centers for Disease Control and Prevention. Late diagnosis was defined by CD4+ T-cell counts <200 cells/mm3. Reasons for HIV testing were analyzed using logistic regression including epidemiologic variables.A total of 858 individuals (37.3%) were included in the late diagnosis group. Individuals with a late diagnosis were older, exposed through heterosexual contact, and demonstrated clinical manifestations of acquired immunodeficiency syndrome (AIDS). The primary reason for HIV testing was a routine health check-up (41%) followed by clinical manifestations (31%) of AIDS. The proportion of individuals with a late diagnosis was higher in individuals tested due to clinical symptoms in public health centers (adjusted odds ratio [AOR], 17.3; 95% CI, 1.7-175) and hospitals (AOR, 4.9; 95% CI, 3.4-7.2) compared to general health check-up. Late diagnosis annually increased in individuals diagnosed by voluntary testing both in public health centers (PHCs, P = 0.017) and in hospitals (P = 0.063). Routine testing due to risky behaviors resulted in earlier detection than testing secondary to health check-ups, although this difference was not statistically significant (AOR, 0.7; P = 0.187). Individuals identified as part of hospital health check-ups more frequently had a late diagnosis (P = 0.001)HIV infection was primarily detected by voluntary testing with identification in PHCs and by testing due to clinical symptoms in hospitals. However, early detection was not influenced by either voluntary testing or general health check-up. It is important to encourage voluntary testing for early detection to decrease the prevalence of HIV infection and AIDS progression.Survival in human immunodeficiency virus (HIV)-infected individuals has improved with
QTL Analysis of Yield Components in Rice Using a Cheongcheong/Nagdong Doubled Haploid Genetic Map  [PDF]
Gyu Hwan Park, Jin-Hee Kim, Kyung-Min Kim
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.59130

In this study, only two of 12 quantitative trait loci (QTLs) affecting yield and yield components were identified in a single year, indicating that individual QTLs are probably sensitive to the environment. A rice growth survey of “Cheongcheong” and “Nag dong” in a doubled haploid population in 2012 revealed that yield capacity was influenced by climate change. Analysis of yield and yield components indicated that five average traits are high in “Cheongcheong”. Frequency distribution tables indicated that panicles per plant (PPP), spike lets per panicle (SPP), and 1000-grain weight (TGW) were normally distributed. The strongest relationship was identified between SPP and seed set percentage (SSP) among phenotypic correlations related to yield and yield components found on chromosomes 2, 3, 6, 8 in 2012. SPP and SSP was a very relevant requisite about quantity. Analysis of QTL about quantity was total 9. In the present study, a doubled haploid population was used to analyze the epistatic effects on yield and yield components in rice. Although other epistatic QTLs were not included in any of the main-effect QTLs, they significantly influenced the traits. These results indicated that epistatic interaction plays an important role in controlling the expression of complex traits. Thus, the utilization of marker-assisted selection in rice breeding programs should take epistatic effects into consideration. Hence, the QTLs responsible for major effects are more suitable for marker-assisted selection programs to improve yield and related traits across different environments.

$N_pN_n$ scheme and the valence proton-neutron interaction
Youngshin Byun,Guanghao Jin,Jin-Hee Yoon,Dongwoo Cha
Physics , 2008, DOI: 10.3938/jkps.54.792
Abstract: We examine the common belief that the $N_pN_n$ scheme is manifested as a direct consequence of the valence proton-neutron interaction which has proven to be a dominant factor in developing collectivity in nuclei. We show that the simplification of the $N_pN_n$-plot of the lowest $2^+$ excitation energy is introduced merely because the excitation energy always decreases when the valence nucleon number becomes larger.
Spin-dependent empirical formula for the lowest excitation energies of the natural parity states in even-even nuclei
Guanghao Jin,Dongwoo Cha,Jin-Hee Yoon
Physics , 2008, DOI: 10.3938/jkps.53.3483
Abstract: We present an empirical expression which holds for the lowest excitation energy of the natural parity states in even-even nuclei throughout the entire periodic table. This formula contains spin-dependent factors so that it is applied to different multipole states with the same model parameters in contrast to the recently proposed empirical expression where the model parameters had to be fitted for each multipole separately.
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