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Search Results: 1 - 10 of 1448 matches for " Jieun Seo "
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Mineral Chemistry of REE-Rich Apatite and Sulfur-Rich Monazite from the Mushgai Khudag, Alkaline Volcanic-Plutonic Complex, South Mongolia  [PDF]
Dorjpalma Enkhbayar, Jieun Seo, Seon-Gyu Choi, Young Jae Lee, Enkhbayar Batmunkh
International Journal of Geosciences (IJG) , 2016, DOI: 10.4236/ijg.2016.71003
Abstract: The Mushgai khudag volcanic-plutonic complex consists of four REE mineralization zones: carbonatite zone, apatite zone, magnetite zone, and monazite zone. REE mineralization occurs within peripheries of alkaline magmatic rocks which consist of porphyritic syenite, microsyenite and quartz syenites. Three types of LREE-rich apatite can be found in the carbonatite, apatite, and monazite zones. Crystal-1 type of apatite exists as hexagonal prismatic shape and is mostly found in the apatite zone, and in syenite. Crystal-2 type of apatite can be exposed also at the apatite zone, and carbonatite zone as brecciated massive crystalline aggregate. Crystal-3 type of apatite demonstrates the compositional zoning texture with monazite as inter-zoning, and is only found in monazite zone. The LREE-bearing apatites from the Mushgai khudag complex are mostly fluorapatite to hydroxyl-bearing fluorapatite with variable REE content. Apatites from the monazite zone present individual sulfur-rich monazite grain, and are formed by comprehensive substitutions.
Clinical and microbiologic characteristics of tcdA-negative variant clostridium difficile infections
Jieun Kim, Hyunjoo Pai, Mi-ran Seo, Jung Oak Kang
BMC Infectious Diseases , 2012, DOI: 10.1186/1471-2334-12-109
Abstract: From September 2008 through January 2010, the clinical characteristics, medication history and treatment outcomes of CDI patients were recorded prospectively. Toxin characterization and antibiotic susceptibility tests were performed on stool isolates of C. difficile.During the study period, we identified 22 cases of CDI caused by tcdA-negative tcdB-positive (A-B+) strains and 105 cases caused by tcdA-positive tcdB-positive (A+B+) strains. There was no significant difference in disease severity or clinical characteristics between the two groups. Previous use of clindamycin and young age were identified as significant risk factors for the acquisition of A-B+ CDI (OR?=?4.738, 95% CI 1.48–15.157, p?=?0.009 and OR?=?0.966, 95% CI 0.935–0.998, p?=?0.038, respectively) in logistic regression.Rates of resistance to clindamycin were 100% and 69.6% in the A-B+ and A+B+ isolates, respectively (p?=?0.006), and the ermB gene was identified in 17 of 21 A-B+ isolates (81%). Resistance to moxifloxacin was also more frequent in the A-B+ than in the A+B+ isolates (95.2% vs. 63.7%, p?=?0.004).The clinical course of A-B+ CDI is not different from that of A+B+ CDI. Clindamycin use is a significant risk factor for the acquisition of tcdA-negative variant strains.
On Cycles in the Transcription Network of Saccharomyces cerevisiae
Jieun Jeong
Quantitative Biology , 2007,
Abstract: We investigate the cycles in the transcription network of S. cerevisiae. Unlike a similar network of E. coli, it contains many cycles. We characterize properties of these cycles and their place in the regulatory mechanism of the cell. Almost all cycles in the transcription network of S. cerevisiae are contained in a single strongly connected component, which we call LSCC (L for ``largest''), except for a single cycle of two transcription factors. Among different physiological conditions, cell cycle has the most significant relationship with LSCC, as the set of 64 transcription interactions that are active in all phases of the cell cycle has overlap of 27 with the interactions of LSCC (of which there are 49). Conversely, if we remove the interactions that are active in all phases of the cell cycle (fewer than 1% of the total), the LSCC would have only three nodes and 5 edges, 4 of which are active only in the stress response subnetwork. LSCC has a special place in the topology of the network and it can be used to define a natural hierarchy in the network; in every physiological subnetwork LSCC plays a pivotal role. Apart from those well-defined conditions, the transcription network of S. cerevisiae is devoid of cycles. It was observed that two conditions that were studied and that have no cycles of their own are exogenous: diauxic shift and DNA repair, while cell cycle, sporulation are endogenous.
Spontaneous Spinal Subdural Hematoma Developed After Weightlifting: A case Report and Review of Literature  [PDF]
JiEun Park, SooMi Lim, Jeong Hyun Yoo
Open Journal of Clinical Diagnostics (OJCD) , 2011, DOI: 10.4236/ojcd.2011.12002
Abstract: Spontaneous spinal subdural hematoma is a rare disease. Several predisposing factors are reported including impaired clotting due to therapeutic anti-coagulation or hematologic disorder, vascular anom-aly, intraspinal tumor, and iatrogenic causes such as lumbar puncture or spinal anesthesia.We report a rare case of spontaneous spinal subdural hematoma developed after weightlifting in a healthy young man treated with conservative treatment.
On cycles in the transcription network of Saccharomyces cerevisiae
Jieun Jeong, Piotr Berman
BMC Systems Biology , 2008, DOI: 10.1186/1752-0509-2-12
Abstract: Almost all cycles in the transcription network of Saccharomyces cerevisiae are contained in a single strongly connected component, which we call LSCC (L for "largest"), except for a single cycle of two transcription factors. The fact that LSCC includes almost all cycles is well explained by the properties of a random graph with the same in- and out-degrees of the nodes.Among different physiological conditions, cell cycle has the most significant relationship with LSCC, as the set of 64 transcription interactions that are active in all phases of the cell cycle has overlap of 27 with the interactions of LSCC (of which there are 49).Conversely, if we remove the interactions that are active in all phases of the cell cycle (25% of interactions to transcription factors), the LSCC would have only three nodes and 5 edges, many fewer than expected. This subgraph of the transcription network consists mostly of interactions that are active only in the stress response subnetwork.We also characterize the role of LSCC in the topology of the network. We show that LSCC can be used to define a natural hierarchy in the network and that in every physiological subnetwork LSCC plays a pivotal role.Apart from those well-defined conditions, the transcription network of Saccharomyces cerevisiae is devoid of cycles. It was observed that two conditions that were studied and that have no cycles of their own are exogenous: diauxic shift and DNA repair, while cell cycle and sporulation are endogenous. We claim that in a certain sense (slow recovery) stress response is endogenous as well.Cycles have a central role in control of continuing processes (for an example, see Hartwell [1]). Therefore we expect the regulatory mechanism of a cell to have many cycles of interactions. Only some of these interactions have the form of a transcription factor (TF for short) regulating expression of a target gene. Our question is: given that there are cycles of transcription interactions, are they important in
Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism
Lee Jieun,Wolfgang Michael J
BMC Biochemistry , 2012, DOI: 10.1186/1471-2091-13-23
Abstract: Background Carnitine Palmitoyltransferase-1c (CPT1c) is a neuron specific homologue of the carnitine acyltransferase family of enzymes. CPT1 isoenzymes transfer long chain acyl groups to carnitine. This constitutes a rate setting step for mitochondrial fatty acid beta-oxidation by facilitating the initial step in acyl transfer to the mitochondrial matrix. In general, neurons do not heavily utilize fatty acids for bioenergetic needs and definitive enzymatic activity has been unable to be demonstrated for CPT1c. Although there are studies suggesting an enzymatic role of CPT1c, its role in neurochemistry remains elusive. Results In order to better understand how CPT1c functions in neural metabolism, we performed unbiased metabolomic profiling on wild-type (WT) and CPT1c knockout (KO) mouse brains. Consistent with the notion that CPT1c is not involved in fatty acid beta-oxidation, there were no changes in metabolites associated with fatty acid oxidation. Endocannabinoids were suppressed in the CPT1c KO, which may explain the suppression of food intake seen in CPT1c KO mice. Although products of beta-oxidation were unchanged, small changes in carnitine and carnitine metabolites were observed. Finally, we observed changes in redox homeostasis including a greater than 2-fold increase in oxidized glutathione. This indicates that CPT1c may play a role in neural oxidative metabolism. Conclusions Steady-state metabolomic analysis of CPT1c WT and KO mouse brains identified a small number of metabolites that differed between CPT1c WT and KO mice. The subtle changes in a broad range of metabolites in vivo indicate that CPT1c does not play a significant or required role in fatty acid oxidation; however, it could play an alternative role in neuronal oxidative metabolism.
Analysis of Awareness and Utilization of BIM in Civil Engineering  [PDF]
MyoungBae Seo, JinUk Kim
Open Journal of Applied Sciences (OJAppS) , 2012, DOI: 10.4236/ojapps.2012.24B038
Abstract: Recently, Building Information Modeling (BIM) has emerged as a hot topic in the construction industry. However, the application of civil engineering, both domestic and foreign, is minor because of the distribution in a wide area, highly liner dependence and difficulty to take advantage of the standard library.? Civil engineering requires a lot of time and financial resources compared to architectural engineering. If BIM is completely applied to civil engineering, it will be possible to manage the schedule and cost using 3D and facilitates effective communication between various stakeholders. For the application of BIM in civil engineering, we surveyed the awareness, utilization and effectiveness of BIM on the civil engineering companies. Also, we derived necessary improvements and analyzed new business areas for BIM application. The results of the study will be used as a reference of development for SOC civil engineering BIM ordering guide and related standard.
Korea’s Construction Business Informatization Overview  [PDF]
MyoungBae Seo, NamGon Kim
Open Journal of Applied Sciences (OJAppS) , 2012, DOI: 10.4236/ojapps.2012.24B004
Abstract: South Korea’s construction industry won orders worth USD 58 billion in 2011, and as such, it has achieved a remarkable growth. However, despite such an impressive quantitative growth, value-added quality growth has been very slow. Thus, the Ministry of Land, Transport and Marine Affairs (MLTM) is pushing ahead with the construction informatization initiative (Construction Continuous Acquisition & Life-cycle Support - CALS) in order to systematically manage a wide range of construction information by stage and to enhance the efficiency of construction costs. This study aims to review the country’s construction CALS to explore a construction development direction.
Effectiveness of Endovascular Coil Embolization of Ruptured Hepatic Artery Pseudoaneurysm  [PDF]
Jung Wook Seo
Advances in Computed Tomography (ACT) , 2017, DOI: 10.4236/act.2017.62002
Abstract: Purpose: To assess the efficacy of endovascular management for ruptured hepatic artery pseudoaneurysm (HAP). Methods: Six cases of HAP in five patients (four men and one women; mean age, 50; range, 28 - 62) were treated with transcatheter arterial coil embolization using microcoil (Boston Scientific, Watertown, MA, USA) and Tornado Coil (Cook, Bloomington, IN, USA) with or without stent graft between January 2007 and September 2008. They were analyzed with regard to the clinical presentation, radiological findings with procedure, and clinical and radiologic outcomes. Results: All patients presented with epigastric pain or gastrointestinal bleeding. The pseudoaneurysms were ranged from 0.6 to 4.4 cm in size and located in the common hepatic artery (n = 1), junction between proper and right hepatic artery (n = 1), proper hepatic artery (n = 2), the left hepatic artery (n = 1), right hepatic artery (n = 1). Embolization was performed with microcoils in all pseudoaneurysmal sac with or without both afferent and efferent segment. A self-expandable stent (n = 1) was also used. Overall technical success was 100% (6 of 6) and complete occlusions of HAPs were achieved in 5 out of 6 cases, 83.3% of clinical success rate. Re-bleeding occurred in one case of stent graft at proper hepatic artery following coil packing for pseudoaneurysmal sac. Clinical success rate of embolization for both afferent and efferent segment was 100% (3 of 3). Procedure-related minor complications happened in 2 of 5 patients, and they were treated conservatively. Conclusion: Transcatheter coil embolization for ruptured HAP is sufficiently effective and additional embolization in both afferent segment and efferent segment can improve clinical success rate.
Acute Epiploic Appendagitis of the Vermiform Appendix: Typical Computed Tomographic Image with Pathologic Correlation  [PDF]
Jung Wook Seo
Advances in Computed Tomography (ACT) , 2017, DOI: 10.4236/act.2017.64004
Abstract:
Epiploic appendages can become ischemic and infarcted, which can present acute abdominal pain that mimics other diseases, such as diverticulitis or appendicitis. Particularly, inflammation of an epiploic appendage attached to the vermiform appendix is a very rare cause of acute abdominal pain, and it is difficult to diagnose this condition preoperatively. We present a case of epiploic appendagitis of the vermiform appendix that was identified with a typical radiologic image and was pathologically confirmed. In addition, we review the literature of similar cases and analyze the clinical and radiologic features of EA of the vermiform appendix.
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