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Search Results: 1 - 10 of 28238 matches for " Jiaxue Zhu "
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The Analysis of Tendency of Transition from Collectivism to Individualism in China
Jiaxue CAO
Cross-Cultural Communication , 2009, DOI: 10.3968/772
Abstract: This essay introduces Individualism and Collectivism dimension of a culture and the differences between the two patterns, indicating possible factors promoting the shift from collectivism to individualism, and describes as well as analyses the current changes in China in different fields and tendency of China to transfer from collectivism to individualism. Key words: Collectivism; Individualism; Post-80s Generation in China Résumé: Cet essai introduit la dimension de l’individualisme et du collectivisme d'une culture et les différences entre ces deux modèles en indiquant les facteurs possibles de promouvoir le passage du collectivisme à l'individualisme, décrit et analyse les changements actuels en Chine dans de différents domaines et la tendance de la transition du collectivisme à l'individualisme. Mots-clés : collectivisme ; individualisme ; la génération post-80 en Chine
RNAi-mediated knockdown of cyclooxygenase2 inhibits the growth, invasion and migration of SaOS2 human osteosarcoma cells: a case control study
Qinghua Zhao, Chuan Wang, Jiaxue Zhu, Lei Wang, Shuanghai Dong, Guoqiao Zhang, Jiwei Tian
Journal of Experimental & Clinical Cancer Research , 2011, DOI: 10.1186/1756-9966-30-26
Abstract: We employed lentivirus mediated-RNA interference technology to knockdown endogenous gene COX-2 expression in human osteosarcoma cells (SaOS2) and analyzed the phenotypical changes. The effect of COX-2 treatment on the proliferation, cell cycle, invasion and migration of the SaOS2 cells were assessed using the MTT, flow cytometry, invasion and migration assays, respectively. COX-2, vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), basic fibroblast growth factor (bFGF) mRNA and protein expression were detected by RT-PCR and western blotting.Our results indicate that a decrease of COX-2 expression in human osteosarcoma cells significantly inhibited the growth, decreased the invasion and migration ability of SaOS2 cells. In addition, it also reduced VEGF, EGF and bFGF mRNA and protein expression.The COX-2 signaling pathway may provide a novel therapeutic target for the treatment of human osteosarcoma.Osteosarcoma is the most common primary malignant tumor arising in bone predominantly affecting children and adolescents [1]. It is also one of the most heterogeneous of human tumors [2]. The 5-year survival rate has increased up to 70% in patients with localized disease, however, the prognosis is very poor and the 5-year survival rate is only 20-30% in patients with metastatic disease at diagnosis [3]. Although an adjuvant treatment regimen after surgical resection seems to prolong survival, the precise treatment protocol of drug-of-choice is still debated because the exact mechanisms the development and progression of osteosarcoma are still largely unknown [4]. Effective systemic therapy capable of reversing the aggressive nature of this disease is currently not available [5]. Therefore, an understanding of the molecular mechanisms of osteosarcoma is one of the most important issues for treatment. New therapeutic strategies are necessary to increase survival rates in patients with osteosarcoma.Cyclooxygenases are key enzymes in the conversion of ar
The Two-Component Signal Transduction System ArlRS Regulates Staphylococcus epidermidis Biofilm Formation in an ica-Dependent Manner
Yang Wu, Jiaxue Wang, Tao Xu, Jingran Liu, Wenqi Yu, Qiang Lou, Tao Zhu, Nianan He, Haijing Ben, Jian Hu, Friedrich G?tz, Di Qu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040041
Abstract: Due to its ability to form biofilms on medical devices, Staphylococcus epidermidis has emerged as a major pathogen of nosocomial infections. In this study, we investigated the role of the two-component signal transduction system ArlRS in regulating S. epidermidis biofilm formation. An ArlRS-deficient mutant, WW06, was constructed using S. epidermidis strain 1457 as a parental strain. Although the growth curve of WW06 was similar to that of SE1457, the mutant strain was unable to form biofilms in vitro. In a rabbit subcutaneous infection model, sterile disks made of polymeric materials were implanted subcutaneously followed with inoculation of WW06 or SE1457. The viable bacteria cells of WW06 recovered from biofilms on the embedded disks were much lower than that of SE1457. Complementation of arlRS genes expression from plasmid in WW06 restored biofilm-forming phenotype both in vivo and in vitro. WW06 maintained the ability to undergo initial attachment. Transcription levels of several genes involved in biofilm formation, including icaADBC, sigB, and sarA, were decreased in WW06, compared to SE1457; and icaR expression was increased in WW06, detected by real-time reverse-transcription PCR. The biofilm-forming phenotype was restored by overexpressing icaADBC in WW06 but not by overexpressing sigB, indicating that ArlRS regulates biofilm formation through the regulation of icaADBC. Gel shift assay showed that ArlR can bind to the promoter region of the ica operon. In conclusion, ArlRS regulates S. epidermidis biofilm formation in an ica-dependent manner, distinct from its role in S. aureus.
A Decision Making Method that Has Favouritism Information for the Index Attribute
对指标属性有偏好信息的一种决策方法

Liu Jiaxue,
刘家学

系统工程理论与实践 , 1999,
Abstract: In this paper, we discussed the multiple attribute decision problem that has favouritism information for the index. We used least square method as a tool and established the optimization model that determine the weight of index. Meanwhile, we gave the five scale valuation method of determining the index's weight subjectively. Thus we provided an effective decision method for the multiple attribute decision problem.
THE EFFECT OF VACUUM ANNEALING ON THE ABILITY OF ANTIOXIDATION OF GLASSY Cu-Zr ALLOYS

LIU Zuoquan,ZOU Gang,LI DexiuZHONG Jiaxue,

材料研究学报 , 1988,
Abstract: The effect of annealing on anti-oxidation of glassy alloys Cu50Zr50,Cu55Zr45 and Cu60Zr40 has been studied by differential scanning calorime-try(DSC)and X-ray diffraction.The alloys were prepared by using meltspinning techique in vacuum.Experimental resul
Interface instability modes in freezing colloidal suspensions - revealed from onset of planar instability
Lilin Wang,Jiaxue You,Zhijun Wang,Jincheng Wang,Xin Lin
Physics , 2015,
Abstract: Freezing colloidal suspensions widely exists in nature and industry. Interface instability has attracted much attention for the understandings of the pattern formation in freezing colloidal suspensions. However, the interface instability modes, the origin of the ice banding or ice lamellae, are still unclear. In-situ experimental observation of the onset of interface instability is still absent up to now. Here, by directly imaging the initial transient stage of planar interface instability in directional freezing colloidal suspensions, we proposed three interface instability modes, Mullins-Sekerka instability, global split instability and local split instability. All the three instability modes come from the competition of the solute boundary layer and the particle boundary layer, which only can be revealed from the initial transient stage of planar instability in directional freezing.
Can secondary nucleation exist in ice banding of freezing colloidal suspensions?
Jiaxue You,Jincheng Wang,Lilin Wang,Zhijun Wang,Xiaobing Hu,Junjie Li,Xin Lin
Physics , 2015,
Abstract: The formation mechanism of ice banding in the system of freezing colloidal suspensions, which is of significance in frost heaving, ice-templating porous materials and biological materials, still remains a mystery. Recently, the theory of secondary nucleation and growth of ice has been proposed to explain the emergence of a new ice lens. However, this theory has not been quantitatively examined. Here, we quantitatively measured the initial interfacial undercooling of a new ice lens and the nucleation undercoolings of suspensions. We found that the interfacial undercooling can not satisfy the nucleation undercooling of ice and hence disprove the secondary nucleation mechanism for ice banding.
Interfacial undercooling in the solidification of colloidal suspensions
Jiaxue You,Lilin Wang,Zhijun Wang,Junjie Li,Jincheng Wang,Xin Lin,Weidong Huang
Physics , 2015,
Abstract: Interfacial undercooling is of significant importance on microscopic pattern formation in the solidification of colloidal suspensions. Two kinds of interfacial undercooling are supposed to be involved in freezing colloidal suspensions, i.e. solute constitutional supercooling (SCS) caused by additives in the solvent and particulate constitutional supercooling (PCS) caused by particles. However, quantitatively identification of the interfacial undercooling of freezing colloidal suspensions is still absent and it is still unknown which undercooling is dominant. The revealing of interfacial undercooling is closely related to the design of ice-templating porous materials. Based on quantitative experimental measurements, we show that the interfacial undercooling mainly comes from SCS caused by the additives in the solvent, while the PCS can be ignored. This finding implies that the PCS theory is not the fundamental physical mechanism for patterning in the solidification of colloidal suspensions. Instead, the patterns in ice-templating method can be controlled effectively by adjusting the additives.
In situ observation the interface undercooling of freezing colloidal suspensions with differential visualization method
Jiaxue You,Lilin Wang,Zhijun Wang,Junjie Li,Jincheng Wang,Xin Lin,Weidong Huang
Physics , 2015, DOI: 10.1063/1.4928108
Abstract: Interface undercooling is one of the most significant parameters in the solidification of colloidal suspensions. However, quantitative measurement of interface undercooling of colloidal suspensions is still a challenge. Here, a new experimental facility and gauging method are designed to directly reveal the interface undercooling on both static and dynamic cases. The interface undercooling is visualized through the discrepancy of solid/liquid interface positions between the suspensions and its solvent in a thermal gradient apparatus. The resolutions of the experimental facility and gauging method are proved to be 0.01 K. The high precision of the method comes from the principle of converting temperature measurement into distance measurement in the thermal gradient platform. Moreover, both static and dynamic interface undercoolings can be quantitatively measured.
A Study on the Driving Factors of Tourism Destination Brand Equity Based on Internet Sharing Content: A Case Study of Shenzhen Happy Valley  [PDF]
Ju Zhu, Mingfang Zhu
Journal of Service Science and Management (JSSM) , 2018, DOI: 10.4236/jssm.2018.116039
Abstract: Thanks to increasing mature tourists, continuous innovation on science and technology, improved accessibility of attractions, the destination has to confront the growing competition tourism destinations leading to the importance of consumer based brand equity. The paper, taking the tourists’ evaluation and sharing contents of Shenzhen Happy Valley obtained on Mafengwo website as the text material, constructs a tourism destination brand equity driving factor model with “product”, “experience” and “marketing” as the core category based on the grounded theory Through the study, the driving factors of brand equity of destination are identified, and corresponding suggestions are provided for the management of destination brand equity.
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