Frozen Blastocyst Transfer during in Vitro Fertilization/Intracytoplasmic Sperm Injection Cycle Lowers the Rate of Ectopic Pregnancy
Open Journal of Obstetrics and Gynecology (OJOG)
A total of 1577 in
vitro fertilization/ intra-cytoplasmic cycles were analyzed,
including 757 fresh D3-ET cycles, 429 frozen D3-ET cycles, and 391 frozen D5-ET
differences of ages, the proportion of IVF cycles, the proportion of primary
infertility, and the proportion of tubal factor between three groups were not
clinical pregnancy rate in Frozen D5-ET Group was 62.15%, which was significantly
higher than other two groups (46.10%; 38.93%; P < 0.05). The miscarriage rates of three groups were similar.
The ectopic pregnancy rate in Frozen D5-ET Group was 0.41%, which was
significantly lower than that in Frozen D3-ET Group (2.99%, P < 0.05) and slightly lower than
that in Fresh D3-ET Group (2.29%, P =
0.089). Results from this study show that the transfer of frozen D5 blastocysts
can significantly decrease the incidence rate of ectopic pregnancy.