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Search Results: 1 - 10 of 326381 matches for " Jesús Pastor "
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Reflexión sobre el fin último de la gestión en el sector hospitalario espa?ol
Tejedor,Jesús Pastor;
Gaceta Sanitaria , 2009, DOI: 10.1590/S0213-91112009000200014
Abstract: the european foundation for quality management (efqm) is the most introduced model in spanish hospitals. the main target of this model is the internal and external client's satisfaction. the model of strategic management balanced scorecard (bsc) facilitates the alignment between management and the mission and vision of hospitals. for this reason, we propose a model of integrated management: efqm-bsc. in order to obtain the items of this research, a survey was conducted among managers of spanish hospitals on a battery of 46 indicators, selected from the efqm model, and prioritised and included in the four perspectives of the bsc model. the research shows two possible models of hypothesis: the client model, where the final effect would be the client perspective (patient, staff and society's satisfaction), or the financial model, where the final effect would be the economic and financial results. after a reliability, dimension analysis and a discriminant analysis, it was obtained more consistent indicators which better explain each perspective. the relationship among these perspectives are determined by structural equations based on methods of partial least squares. the research confirms that the client model reflects a better consistency in its hypothesis.
Influence of paroxysmal activity on background synchronization in epileptic records
Jesús Pastor,Guillermo Ortega
Physics , 2012,
Abstract: The presence of spikes and sharp waves in the recordings of epileptic patients may contaminate background signal synchronization in different ways. In this Technical Note, we present a simple procedure for assessing whether a particular synchronization method should be used (or not) with data from neurophysiological recordings commonly used to evaluate epilepsy. The information provided by this procedure makes it possible to differentiate true background synchronization from spike synchronization. This issue is particularly relevant when differentiating between the mechanisms underlying the onset of interictal epileptiform discharges and limbic network dynamics.
New network and synchronization approaches in focal epilepsy research and treatment  [PDF]
Jesús Pastor, Rafael G. Sola, Lorena Vega Zelaya, Oscar Garnés, Guillermo Ortega
Health (Health) , 2013, DOI: 10.4236/health.2013.56A1001
Abstract:

Traditional approaches to focal epileptic surgery rely in the identification and resection of the epileptic zone. However, a significant minority of epileptic patients continue to experience seizures after surgery, a fact that shows how difficult it is to define this concept. In this work we will review some of the recent advances in the use of complex network theory and synchronization analysis in the study of neurophysiological epileptic records which shed new light on fragmented understanding of the epilepsy dynamic we have today. More important would be the potential treatments which could be implemented from the new information and change of perspective gathered by using this methodology, particularly the substitution of the traditional resective surgery in temporal lobe epilepsy patients.

Productive and Reproductive Parameters of Does as a Function of Sex of Siblings During Gestation
Miguel Mellado,Francisco Pastor,Jes?s Mellado
Journal of Animal and Veterinary Advances , 2012,
Abstract: This study examined the influence of sex ratio during multiple pregnancies on some reproductive and reproductive parameters of adult goats under intensive conditions. Goats were grouped according to sex of fetuses of the litter: females (F,FF or FFF; n= 356) and females and males (FM, FFM or FMM; n=270). Birth weight (3.11 ? 0.04 vs 2.95 ? 0.06 kg), weight at 25 days of age (7.36 ? 0.16 vs 7.27 ? 0.25 kg) and average daily gain from 1 to 25 days of age (170 ? 6 vs 174 ? 9 g) were similar between does born with a female twin and does born co-twin to a male. No effects of sex of adjacent littermate were found on pregnancy rate (0.71 vs 0.72; 1855 total services), prolificacy (1.63 ? 0.02 vs 1.66 ? 0.03) and age at first kidding (700 ? 12 vs 721 ?18). These findings indicate that the coexistence of a female with one or two males during the gestation period do not alter the growth and some reproductive performance of adult does.
Extrahippocampal Desynchronization in Nonlesional Temporal Lobe Epilepsy
Jesús Pastor,Eduardo G. Navarrete,Rafael G. Sola,Guillermo J. Ortega
Epilepsy Research and Treatment , 2012, DOI: 10.1155/2012/823683
Abstract: Although temporal lobe epilepsy (TLE) is traditionally associated with both hypersynchronous activity in the form of interictal epileptic discharges and hippocampal sclerosis, recent findings suggest that desynchronization also plays a central role in the dynamics of this pathology. The objective of this work is to show the imbalance existing between mesial activities in patients suffering from mesial TLE, with normal mesial structures. Foramen ovale recordings from six patients with mesial TLE and one with lateral TLE were analyzed through a cluster analysis and synchronization matrices. None of the patients present findings in the MRI presurgical evaluation. Numerical analysis was carried out in three different situations: awake and sleep interictal and also during the preictal stage. High levels of desynchronization ipsilateral to the epileptic side were present in mesial TLE patients. Low levels of desynchronization were present in the lateral TLE patient during the interictal stage and almost zero in the preictal stage. Implications of these findings in relation with seizure spreading are discussed. 1. Introduction Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy, where the epileptogenic area is located at some part of the temporal lobe. Mesial TLE (MTLE) refers to those cases where the suspected source of epileptogenic activity is located in the mesial area of the temporal lobe [1], and lateral TLE (LTLE), instead, where the focus is located in the lateral side. MTLE is often associated with structural lesions and/or functional deficiency in one or several (dual pathology) mesial structures of the temporal lobe, with hippocampal sclerosis (HS) as the most common underlying abnormality [2]. However, pathological findings of damage in the amygdala and parahippocampal region, which in turn is subdivided into the entorhinal cortex (EC), perirhinal cortex (PC), and parahippocampal cortex (PPC), are also reported [3, 4]. A significant minority of MTLE patients have no pathological findings on magnetic resonance imaging (MRI), even though lateralization may be correctly performed by neurophysiological methods [5, 6]. Normal underlying mesial structures play a key role in our understanding of the pathogenesis of MTLE, as they oblige us to ask whether mesial sclerosis (MS) is either the cause or the effect in MTLE [7]. Pathophysiology in MTLE can be explained according to two models: (1) the “focal” model suggests that a single pathological region in the mesial temporal lobe is responsible for seizure origin, establishing a link
Stability of Synchronization Clusters and Seizurability in Temporal Lobe Epilepsy
Agostina Palmigiano, Jesús Pastor, Rafael García de Sola, Guillermo J. Ortega
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0041799
Abstract: Purpose Identification of critical areas in presurgical evaluations of patients with temporal lobe epilepsy is the most important step prior to resection. According to the “epileptic focus model”, localization of seizure onset zones is the main task to be accomplished. Nevertheless, a significant minority of epileptic patients continue to experience seizures after surgery (even when the focus is correctly located), an observation that is difficult to explain under this approach. However, if attention is shifted from a specific cortical location toward the network properties themselves, then the epileptic network model does allow us to explain unsuccessful surgical outcomes. Methods The intraoperative electrocorticography records of 20 patients with temporal lobe epilepsy were analyzed in search of interictal synchronization clusters. Synchronization was analyzed, and the stability of highly synchronized areas was quantified. Surrogate data were constructed and used to statistically validate the results. Our results show the existence of highly localized and stable synchronization areas in both the lateral and the mesial areas of the temporal lobe ipsilateral to the clinical seizures. Synchronization areas seem to play a central role in the capacity of the epileptic network to generate clinical seizures. Resection of stable synchronization areas is associated with elimination of seizures; nonresection of synchronization clusters is associated with the persistence of seizures after surgery. Discussion We suggest that synchronization clusters and their stability play a central role in the epileptic network, favoring seizure onset and propagation. We further speculate that the stability distribution of these synchronization areas would differentiate normal from pathologic cases.
Etapa familiar que se inicia con el nacimiento del primer hijo
Pérez Cárdenas,Clara; Rodríguez Quintana,Tamara; Aguiar Pastor,Cecilia de Jesús;
Revista Cubana de Medicina General Integral , 2000,
Abstract: as the evolutive stages of the family as a group are little appoached by medical literature, we decided to deepen in that one that starts with the birth of the first child for considering it as a period of many expectations and new tasks to undertake in the family and personal life. a descriptive, longitudinal and retrospective evaluation of the fundamental conflict perceived by the parents in this stage, of the feelings resulting from facing that event that defines it and of the attempts to solve the problems arising during that period was made. we worked with 2 groups: one with the child enrolled in the day care center and the other with children that developed in the family environment only. among the results, we found that besides being desired children, fathers recognized their participation in their attention and considered that mothers played a fundamental role in the decision-making. the economic affectation was the main conflict observed in both parents from the 2 studied groups. no significant differences were found at least in most of the variables explored in the 2 groups of families that participated in the study
Etapa familiar que se inicia con el nacimiento del primer hijo
Clara Pérez Cárdenas,Tamara Rodríguez Quintana,Cecilia de Jesús Aguiar Pastor
Revista Cubana de Medicina General Integral , 2000,
Abstract: Las etapas evolutivas de la familia como grupo, son un tema poco abordado en la literatura médica, de ahí que nos entusiasmara la idea de profundizar en aquella que se inicia con el nacimiento del primer hijo, por considerarla un período en la vida familiar y personal de muchas expectativas y tareas nuevas a afrontar. Con carácter descriptivo, longitudinal y retrospectivo evaluamos cuál es el conflicto fundamental que perciben los padres en esta etapa, sentimientos que genera el afrontar ese evento que la define y los intentos de solución, a los problemas de este período. Trabajamos con 2 grupos: 1 que tuviera a su descendiente matriculado en el Círculo Infantil, y otro con ni os que se desarrollan únicamente en el ambiente familiar. Entre los resultados encontramos que además de ser hijos deseados, los padres refieren participación en la atención de éstos reconociéndose a la madre como figura fundamental en la toma de decisiones. La afectación económica es el conflicto principal percibido por ambos padres en los 2 grupos estudiados, no encontrándose diferencias importantes entre los 2 grupos de familias que participaron en el estudio, al menos en la mayoría de las variables exploradas As the evolutive stages of the family as a group are little appoached by medical literature, we decided to deepen in that one that starts with the birth of the first child for considering it as a period of many expectations and new tasks to undertake in the family and personal life. A descriptive, longitudinal and retrospective evaluation of the fundamental conflict perceived by the parents in this stage, of the feelings resulting from facing that event that defines it and of the attempts to solve the problems arising during that period was made. We worked with 2 groups: one with the child enrolled in the day care center and the other with children that developed in the family environment only. Among the results, we found that besides being desired children, fathers recognized their participation in their attention and considered that mothers played a fundamental role in the decision-making. The economic affectation was the main conflict observed in both parents from the 2 studied groups. No significant differences were found at least in most of the variables explored in the 2 groups of families that participated in the study
Participación espa?ola en los Congresos de la Sociedad Internacional de Urología en el siglo XX
Pérez Albacete,Mariano; Tornero Ruíz,Jesús; Server Pastor,Gerardo; Ponce de León Castell,Ignacio;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000800022
Abstract: objectives: with the occasion of the centenary of the constitution in 1907 of the international society of urology, initially named association, we point at the topics treated and analyze the presence of the spanish urologists in the foundation act as well as their role and contributions in the meetings during the 20th century. methods: we obtained the data from the information in various periodic publications, from the memories of some participant urologists and from the meeting records. results: we obtained notes from the foundation meeting of the international association and two congresses, and also from the 25 congresses of the society. we mainly extract data from the records edited by the meeting secretary, about the assistance of spanish urologists and their contribution with conferences or communications and also about the relevance they have had holding positions within the organization. conclusions: from 1907 the presence of spanish urologists both in the association and the international society of urology has been a constant. during the first half of the century, a time when our urology was in a period of consolidation, the people in charge of the main urology departments in big hospitals in our country where the ones that could transmit their experience, with a level and quality comparable with the rest of europeans. during the second half, once the nations recovered from wars, the scienti.c activity continued with an increasing spanish contribution, which extended all over the country with the creation of the net of social security hospitals. they had hierarchical urology departments that performed study and analysis of their case series and started clinical and experimental research, significantly increasing the number of spanish communications, mainly in congresses celebrated in spanish speaking or european cities. as a consequence of their participation, three of the 25 meetings organized during the 20th century have been held in spain. the spanish
Factors associated with falls among older adults living in institutions
Damián Javier,Pastor-Barriuso Roberto,Valderrama-Gama Emiliana,de Pedro-Cuesta Jesús
BMC Geriatrics , 2013, DOI: 10.1186/1471-2318-13-6
Abstract: Background Falls have enormous impact in older adults. Yet, there is insufficient evidence regarding the effectiveness of preventive interventions in this setting. The objectives were to measure the frequency of falls and associated factors among older people living institutions. Methods Data were obtained from a survey on a probabilistic sample of residents aged ≥65 years, drawn in 1998-99 from institutions of Madrid (Spain). Residents, their caregivers, and facility physicians were interviewed. Fall rates were computed based on the number of physician-reported falls in the preceding 30 days. Adjusted rate ratios were computed using negative binomial regression models, including age, sex, cognitive status, functional dependence, number of diseases, and polypharmacy. Results The final sample comprised 733 residents. The fall rate was 2.4 falls per person-year (95% confidence interval [CI], 2.04-2.82). The strongest risk factor was number of diseases, with an adjusted rate ratio (RR) of 1.32 (95% CI, 1.17-1.50) for each additional diagnosis. Other variables associated with falls were: urinary incontinence (RR = 2.56 [95% CI, 1.32-4.94]); antidepressant use (RR = 2.32 [95% CI, 1.22-4.40]); arrhythmias (RR = 2.00 [95% CI, 1.05-3.81]); and polypharmacy (RR = 1.07 [95% CI, 0.95-1.21], for each additional medication). The attributable fraction for number of diseases (with reference to those with ≤ 1 condition) was 84% (95% CI, 45-95%). Conclusions Number of diseases was the main risk factor for falls in this population of institutionalized older adults. Other variables associated with falls, probably more amenable to preventive action, were urinary incontinence, antidepressants, arrhythmias, and polypharmacy. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3916151157277337
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