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Search Results: 1 - 10 of 3608 matches for " Jens Aberle "
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Complications, Mineral and Vitamin Deficiencies: Comparison between Roux-en-Y Gastric Bypass and Sleeve Gastrectomy  [PDF]
Nina Sauer, Jan Wienecke, Clarissa Schulze zur Wiesfch, Stefan Wolter, Oliver Mann, Jens Aberle
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.412106

Objective: Nutritional deficiencies are known side-effects of bariatric surgeries, specifically in those that bypass the proximal intestine. Therefore, in clinical practice, vitamin and mineral supplementations are often necessary after such operations. It was our intention to evaluate, whether alimentary deficiencies occur with the same frequency in patients following Sleeve-Gastrectomy (SG) compared to Roux-en-Y Gastric Bypass (RYGB) surgeries. Methods: We conducted a retrospective data analysis of 171 patients (121 RYGB, 50 SG). Vitamin levels were compared between SG and RYGB patients over the first post-operative year. Furthermore, regression analysis was performed with regard to vitamin and iron supplementations and their recommended dosages. Complications occurring within the first post-surgical year were documented as well. Results: Other than vitamin B6 deficiency, which was found to be more frequent in SG patients, there was no other significant difference regarding the type of operation and the number of patients who had these deficiencies. There was no significant difference in average vitamin and iron levels between RYGB and SG. A minimum dose of 1000 IU vitamin D per day was necessary to affect vitamin D levels. The intramuscular administration of vitamin B12 was the only route found to be effective. Complications within the first year were rare. Conclusions: Against common assumptions, vitamin and iron deficiencies in SG patients are not less frequent in the first post-surgical year in comparison to RYGB patients. Standard supplementations should include iron in premenopausal women: Vitamin D at least 1000 IU per day and vitamin B12 i.m. administration in case of a deficiency.

Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women
Jens Aberle, Inga Hopfer, Frank Ulrich Beil, Udo Seedorf
International Journal of Medical Sciences , 2006,
Abstract: Background: The +T294C polymorphism in PPARδ represents a functional SNP affecting transcriptional activity of the PPARδ gene. To address whether this polymorphism is associated with the risk for coronary heart disease and/or plasma lipid levels in women, we studied a group of 967 female patients with hyperlipidaemia in the presence (n=453) or absence (n=514) of coronary heart disease. Methods: 967 female patients with or without coronary heart disease were genotyped using mutagenically separated polymerase chain reaction (MS-PCR). Statistical analysis was performed according to genotype with parameters of lipid metabolism as dependant variables. Results: A highly significant association between the rare C allele and lower plasma HDL concentrations was found in female subjects. The effect remained significant after correcting for multiparametric testing according to Bonferoni and was seen only in subjects with a BMI below the median. Moreover, a significant association of the C-allele with coronary heart disease and BMI was obtained. Regarding the entire group, trends towards higher VLDL and LDL levels were observed. Conclusions: Our data show for the first time that the PPARδ +T294C polymorphism is associated with lipid levels and coronary heart disease in women. However, the molecular mechanism of action remains to be elucidated.
Recent Advances in Solar Cells
Armin Aberle
Advances in OptoElectronics , 2008, DOI: 10.1155/2007/60319
Double Quantum Entanglement to Understand Superconductivity  [PDF]
Jens Cordelair
World Journal of Condensed Matter Physics (WJCMP) , 2013, DOI: 10.4236/wjcmp.2013.34032

The feature of quantum entanglement in doublet and multiplet systems is briefly described and used to create a new model for the superconducting phase.

Superconductivity  [PDF]
Jens Cordelair
World Journal of Condensed Matter Physics (WJCMP) , 2014, DOI: 10.4236/wjcmp.2014.44026
Abstract: The feature of quantum entanglement is used to create a new model for the superconducting state.
Entanglement: A Modern Aspect of Nature  [PDF]
Jens Cordelair
World Journal of Condensed Matter Physics (WJCMP) , 2015, DOI: 10.4236/wjcmp.2015.53025
Abstract: The intention of this paper is to provide an easy to understand introduction to the peculiarities of entangled systems. A novel description for strong (mass entanglement) and weak (spin-or-bital and thermal entanglement) quantum entangled particles is discussed and applied to the phenomena of superconductivity, superfluidity and ultracold gases. A brief statement about how to represent the physical reality of quantum-entanglement as Quantum-Field-Theory (QFT) is noted.
Polycrystalline Silicon Thin-Film Solar Cells on AIT-Textured Glass Superstrates
Per I. Widenborg,Armin G. Aberle
Advances in OptoElectronics , 2007, DOI: 10.1155/2007/24584
Abstract: A new glass texturing method (AIT—aluminium-induced texturisation) has recently been developed by our group. In the present work, the potential of this method is explored by fabricating PLASMA poly-Si thin-film solar cells on glass superstrates that were textured with the AIT method. Using an interdigitated metallisation scheme with a full-area Al rear contact, PLASMA cells with an efficiency of up to 7% are realised. This promising result shows that the AIT glass texturing method is fully compatible with the fabrication of poly-Si thin-film solar cells on glass using solid phase crystallisation (SPC) of PECVD-deposited amorphous silicon precursor diodes. As such, there are now two distinctly different glass texturing methods—the AIT method and CSG Solar's glass bead method—that are known to be capable of producing efficient SPC poly-Si thin-film solar cells on glass.
Experimental Assessment of the Role of Acetaldehyde in Alcoholic Cardiomyopathy
Aberle II Nicholas S.,Ren Jun
Biological Procedures Online , 2003, DOI: 10.1251/bpo41
Abstract: Alcoholism is one of the major causes of non-ischemic heart damage. The myopathic state of the heart due to alcohol consumption, namely alcoholic cardiomyopathy, is manifested by cardiac hypertrophy, compromised ventricular contractility and cardiac output. Several mechanisms have been postulated for alcoholic cardiomyopathy including oxidative damage, accumulation of triglycerides, altered fatty acid extraction, decreased myofilament Ca2+ sensitivity, and impaired protein synthesis. Despite intensive efforts to unveil the mechanism and ultimate toxin responsible for alcohol-induced cardiac toxicity, neither has been clarified thus far. Primary candidates for the specific toxins are ethanol, its first and major metabolic product - acetaldehyde (ACA) and fatty acid ethyl esters. Evidence from our lab suggests that ACA directly impairs cardiac function and promotes lipid peroxidation resulting in oxidative damage. The ACA-induced cardiac contractile depression may be reconciled with inhibitors of Cytochrome P-450 oxidase, xanthine oxidase and lipid peroxidation Unfortunately, the common methods to investigate the toxicity of ACA have been hampered by the fact that direct intake of ACA is toxic and unsuitable for chronic study, which is unable to provide direct evidence of direct cardiac toxicity for ACA. In order to overcome this obstacle associated with the chemical properties of ACA, our laboratory has used the chronic ethanol feeding model in transgenic mice with cardiac over-expression of alcohol dehydrogenase (ADH) and an in vitro ventricular myocyte culture model. The combination of both in vivo and in vitro approaches allows us to evaluate the role of ACA in ethanol-induced cardiac toxicity and certain cellular signaling pathways leading to alcoholic cardiomyopathy.
Detailed Micro Raman Spectroscopy Analysis of Doped Silicon Thin Film Layers and Its Feasibility for Heterojunction Silicon Wafer Solar Cells  [PDF]
Z. P. Ling, J. Ge, R. Stangl, A. G. Aberle, T. Mueller
Journal of Materials Science and Chemical Engineering (MSCE) , 2013, DOI: 10.4236/msce.2013.15A001

Hydrogenated doped silicon thin films deposited using RF (13.56 MHz) PECVD were studied in detail using micro Raman spectroscopy to investigate the impact of doping gas flow, film thickness, and substrate type on the film characteristics. In particular, by deconvoluting the micro Raman spectra into amorphous and crystalline components, qualitative and quantitative information such as bond angle disorder, bond length, film stress, and film crystallinity can be determined. By selecting the optimum doped silicon thin film deposition conditions, and combining our p-doped and n-doped silicon thin films in different heterojunction structures, we demonstrate both (i) an efficient field effect passivation and (ii) further improvement to c-Si/a-Si:H(i) interface defect density with observed improvement in implied open-circuit voltage VOC and minority carrier lifetimes across all injections levels of interest. In particular, the heterojunction structure (a-Si:H(p)/a-Si:H(i)/c-Si(n)/a-Si:H(i)/a-Si:H(p)) demonstrates a minority carrier lifetime of 2.4 ms at an injection level of 1015 cm-3, and a high implied open-circuit voltage of 725 mV. Simulation studies reveal a strong dependence of the interface defect density Dit on the heterojunction silicon wafer solar cell performance, affected by the deposition conditions of the overlying doped silicon thin film layers. Using our films, and a fitted Dit of 5 × 1010 cm-2·eV-1

Rapid Thermal Annealing and Hydrogen Passivation of Polycrystalline Silicon Thin-Film Solar Cells on Low-Temperature Glass
Mason L. Terry,Daniel Inns,Armin G. Aberle
Advances in OptoElectronics , 2007, DOI: 10.1155/2007/83657
Abstract: The changes in open-circuit voltage (Voc), short-circuit current density (Jsc), and internal quantum efficiency (IQE) of aLuminum induced crystallization, ion-assisted deposition (ALICIA) polycrystalline silicon thin-film solar cells on low-temperature glass substrates due to rapid thermal anneal (RTA) treatment and subsequent remote microwave hydrogen plasma passivation (hydrogenation) are examined. Voc improvements from 130 mV to 430 mV, Jsc improvements from 1.2 mA/cm2 to 11.3 mA/cm2, and peak IQE improvements from 16% to > 70% are achieved. A 1-second RTA plateau at 1000°C followed by hydrogenation increases the Jsc by a factor of 5.5. Secondary ion mass spectroscopy measurements are used to determine the concentration profiles of dopants, impurities, and hydrogen. Computer modeling based on simulations of the measured IQE data reveals that the minority carrier lifetime in the absorber region increases by 3 orders of magnitude to about 1 nanosecond (corresponding to a diffusion length of at least 1 μm) due to RTA and subsequent hydrogenation. The evaluation of the changes in the quantum efficiency and Voc due to RTA and hydrogenation with computer modeling significantly improves the understanding of the limiting factors to cell performance.
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