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Search Results: 1 - 10 of 408 matches for " Jeanette Osban "
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Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity
Mark Frank, Qing Yang, Jeanette Osban, Joseph T Azzarello, Marcia R Saban, Ricardo Saban, Richard A Ashley, Jan C Welter, Kar-Ming Fung, Hsueh-Kung Lin
BMC Complementary and Alternative Medicine , 2009, DOI: 10.1186/1472-6882-9-6
Abstract: Frankincense oil-induced cell viability was investigated in human bladder cancer J82 cells and immortalized normal bladder urothelial UROtsa cells. Temporal regulation of frankincense oil-activated gene expression in bladder cancer cells was identified by microarray and bioinformatics analysis.Within a range of concentration, frankincense oil suppressed cell viability in bladder transitional carcinoma J82 cells but not in UROtsa cells. Comprehensive gene expression analysis confirmed that frankincense oil activates genes that are responsible for cell cycle arrest, cell growth suppression, and apoptosis in J82 cells. However, frankincense oil-induced cell death in J82 cells did not result in DNA fragmentation, a hallmark of apoptosis.Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Microarray and bioinformatics analysis proposed multiple pathways that can be activated by frankincense oil to induce bladder cancer cell death. Frankincense oil might represent an alternative intravesical agent for bladder cancer treatment.Frankincense resin is obtained from trees of the genus Boswellia (family Burseraceae). Incisions are made in the trunks of the trees to produce exuded gum, which appears as milk like resin. The resin hardens into orange-brown gum resin known as frankincense. There are numerous species and varieties of frankincense trees, including Boswellia serrata in India, Boswellia carteri in East Africa and China, Boswellia frereana in Somalia, and Boswellia sacra in Arabia, each producing a slightly different type of resin. Differences in soil and climate create more diversity in the resins, even within the same species. The aroma from these resins is valued for its presumed healing properties and superior qualities for religious rituals since the time of the ancient Egyptians [1], and has been used in incense, fumigants, and as a fixative in perfumes.Frankincense resin has been considered throughout th
Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment
Mark Frank, Shirley Wang, Amita Aggarwal, Nicholas Knowlton, Kaiyu Jiang, Yanmin Chen, Ryan McKee, Brad Chaser, Timothy McGhee, Jeanette Osban, James N Jarvis
BMC Medical Genomics , 2009, DOI: 10.1186/1755-8794-2-9
Abstract: RNA was separately extracted from peripheral blood neutrophils and mononuclear leukocytes, labeled, and hybridized to genome level microarrays to generate expression profiles of children with polyarticular juvenile idiopathic arthritis, juvenile dermatomyositis relative to childhood controls. Statistically significantly differentially expressed genes were identified from samples of each disease relative to controls. Functional network analysis identified interactions between products of these differentially expressed genes.In silico models of both diseases demonstrated similar features with properties of scale-free networks previously described in physiologic systems. These networks were observable in both cells of the innate immune system (neutrophils) and cells of the adaptive immune system (peripheral blood mononuclear cells).Genome-level transcriptional profiling from childhood onset rheumatic diseases suggested complex interactions in two arms of the immune system in both diseases. The disease associated networks showed scale-free network patterns similar to those reported in normal physiology. We postulate that these features have important implications for therapy as such networks are relatively resistant to perturbation.Genome-based technologies provide us with an unprecedented capacity to understand complex biological systems and their relationship to health and disease. This is especially true for complex biological traits (e.g., atherosclerosis, hypertension), which have largely eluded our understanding using conventional, reductionist approaches. Indeed, even single-gene traits have demonstrated previously unsuspected levels of complexity when scrutinized through the lens of whole-genome technologies [1-3]Chronic inflammatory diseases such as rheumatoid arthritis (RA) and juvenile dermatomyositis (JDM) are examples of human diseases whose etiologies and pathogenic mechanisms remain incompletely understood. Once thought to be purely "autoimmune" diseases
The narratives behind the numbers: An approach to mixed methods research within the alcohol research field
Jeanette stergaard
Nordic Studies on Alcohol and Drugs , 2011, DOI: 10.2478/v10199-011-0041-0
Abstract: AIM - This article introduces a conceptual framework for conducting mixed methods within the alcohol research field by suggesting that any data analysis - qualitative or quantitative - is also a narrative or social representation. Theoretically, the paper draws on Andrew Abbott (1997; 1998) and Howard Becker (2007), arguing that three ordered forms of representation are performed in quantitative analyses based on survey studies: The first order of representation refers to how participants respond to or interpret a survey question; the second to the arrangement and interpretation of variables in quantitative analysis and shows that measurements can have networks of meanings and the third to ways of merging quantitative analysis with other material, such as qualitative data. DATA AND METHOD - Empirically, the paper illustrates the first order of representation through an analysis of 13 focus group interviews. In these young people discussed selected international survey questions, which later were used in two representative surveys on alcohol and illegal drug use, conducted in 2005 amongst 2 000 15-16-year-olds and in 2008 amongst 5 000 17-19-year-olds. CONCLUSION - The article discusses how insights of the first order of representation are useful when researchers wish to carry out the second and third orders of representation.
Jeanette Weideman
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad , 2012,
Abstract: An increase in economic globalisation and international trade has amounted to an increase in the number of multinational enterprises that have debt, own assets and conduct business in various jurisdictions around the world. This, coupled with the recent worldwide economic recession, has inevitably caused the increased occurrence of multinational financial default, also known as cross-border insolvency (CBI). The legal response to this trend has, inter alia, produced two important international instruments that were designed to address key issues associated with CBI. Firstly, the United Nations Commission on International Trade Law (UNCITRAL) adopted the UNCITRAL Model Law on Cross-Border Insolvency (the Model Law) in 1997, which has been adopted by nineteen countries including the United States of America and South Africa. Secondly, the European Union (EU) adopted the European Council Regulation on Insolvency Proceedings (EC Regulation) in 2000. Both the EC Regulation and Chapter 15 adopt a “modified universalist” approach towards CBI matters. Europe and the United States of America are currently the world leaders in the area of CBI and the CBI legislation adopted and applied in these jurisdictions seems to be effective. As South Africa’s Cross-Border Insolvency Act is not yet effective, there is no local policy guidance available to insolvency practitioners with regard to the application of the Model Law. At the basis of this article is the view that an analysis of the European and American approaches to CBI matters will provide South African practitioners with valuable insight, knowledge and lessons that could be used to understand and apply the principles adopted and applied in terms of the EC Regulation and Chapter 15, specifically the COMI concept, the “establishment” concept in the case of integrated multinational enterprises and related aspects.
Development of a Music Therapy Service in an Australian Public Rehabilitation Hospital
Jeanette Tamplin
Voices: A World Forum for Music Therapy , 2006,
Abstract: It is often challenging to find information about the details and development of clinical music therapy programs in other parts of the world. This article addresses a gap in the literature by describing the evolution of a neurological rehabilitation program over the past two years in Melbourne, Australia. After providing some local details on the development of rehabilitation music therapy in this part of the world, a brief rationale is offered for the place of music therapy in clinical rehabilitation services. This is followed by a detailed description of the implementation, operation and evaluation of the music therapy program established at the Royal Talbot Rehabilitation Centre in 2004. Music therapy in adult neurological rehabilitation is still an emerging area of practice in Australia. Although the first music therapy service for adult rehabilitation was piloted and developed here over 13 years ago, few rehabilitation facilities currently employ music therapy as a standard part of rehabilitation service. Although research and practice of music therapy in rehabilitation internationally is relatively new, it has been practiced for around 20 to 30 years in the United Kingdom and the United States of America respectively. The scarcity of music therapy positions in rehabilitation facilities in Australia is possibly a reflection of the lack of understanding of music therapy on the part of funding bodies and the shortage of rigorous music therapy research in this field. The establishment of new music therapy positions in rehabilitation facilities reflects the development of music therapy in neurorehabilitation internationally in terms of research, clinical practice and publications.
Preparing for the Online Catalog
  Jeanette Mosey
Journal of Library and Information Science , 1982,
Abstract: 頁次:54-61
Deformations of Quantum Symmetric Algebras Extended by Groups
Jeanette Shakalli
Mathematics , 2012,
Abstract: We discuss a general construction of a deformation of a smash product algebra coming from an action of a particular Hopf algebra. This Hopf algebra is generated by skew-primitive and group-like elements, and depends on a complex parameter. The smash product algebra is defined on the quantum symmetric algebra of a finite-dimensional vector space and a group. In particular, an application of this result has enabled us to find a deformation of such a smash product algebra which is, to the best of our knowledge, the first known example of a deformation in which the new relations in the deformed algebra involve elements of the original vector space. Using Hochschild cohomology, we show that the resulting deformations are nontrivial by giving the precise characterization of the infinitesimal.
Improving First Year Nursing Student’s Test Scores through Pediatric Simulation  [PDF]
Jeanette Harris, Tamara Berghout, Pamela Anderson
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.58076
Abstract: Background: Student test scores in the pediatric portion were at a national percentile rank of 30, which was concerning. It was theorized that the main contributor to this dilemma was that the majority of students were not able to have a pediatric clinical experience. Objective: The purpose of this project was to determine if the addition of pediatric simulation scenarios would have an impact on student learning as evidenced by end of level test scores. Method: A convenience sample (n = 100) of first year nursing students attending a university in the western United States participated in this project. This was a mixed methods study. A quasi-experimental design was used to compare test scores of both a non-intervention group and an intervention group of students. A 5 point Likert scale questionnaire was also using post-intervention to assess for changes in perceptions of self-confidence. Results: After implementation of the pediatric focused scenarios, students’ test scores increased to the 95th percentile. This 65 percentile increase is a significant change that suggests that pediatric simulation is effective in improving student exam performance. In addition, 81% of students also reported perceptions of increased levels of self-confidence after implementation of simulation scenarios. Conclusion: The findings suggest that simulation is an effective way to create alternative pediatric clinical experiences which can, in turn, increase student comprehension, test scores, and self-confidence.
Mapping Groundwater Dependent Ecosystems in California
Jeanette Howard,Matt Merrifield
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0011249
Abstract: Most groundwater conservation and management efforts focus on protecting groundwater for drinking water and for other human uses with little understanding or focus on the ecosystems that depend on groundwater. However, groundwater plays an integral role in sustaining certain types of aquatic, terrestrial and coastal ecosystems, and their associated landscapes. Our aim was to illuminate the connection between groundwater and surface ecosystems by identifying and mapping the distribution of groundwater dependent ecosystems (GDEs) in California.
The perceptions of danish physiotherapists on the ethical issues related to the physiotherapist-patient relationship during the first session: a phenomenological approach
Jeanette Praestegaard, Gunvor Gard
BMC Medical Ethics , 2011, DOI: 10.1186/1472-6939-12-21
Abstract: A qualitative approach was chosen and semi-structured interviews with 21 physiotherapists were carried out twice and analysed by using a phenomenological framework.Four descriptive themes emerged: general reflections on ethics in physiotherapy; the importance of the first physiotherapy session; the influence of the clinical environment on the first session and; reflections and actions upon beneficence towards the patient within the first session. The results show that the first session and the clinical context in private practice are essential from an ethical perspective.Ethical issues do occur within the first session, the consciousness about ethical issues differs in Danish physiotherapy private practice, and reflections and acts are to a lesser extent based on awareness of ethical theories, principles and ethical guidelines. Beneficence towards the patient is a fundamental aspect of the physiotherapists' understanding of the first session. However, if the physiotherapist lacks a deeper ethical awareness, the physiotherapist may reason and/or act ethically to a varying extent: only an ethically conscious physiotherapist will know when he or she reflects and acts ethically. Further exploration of ethical issues in private practice is recommendable, and as management policy is deeply embedded within the Danish public sector there are reasons to explore public contexts of physiotherapy as well.Physiotherapy in private practice involves mainly a meeting between two partners: the physiotherapist and the patient. In the meeting, power asymmetry between the two partners is a condition that the physiotherapist has to handle. The asymmetry of power is based on the partner's power inequality in defining and setting the situation: generally, the one needs help and the other has the adequate skills to offer assistance [1]. In addition to laws and guidelines as regulation of the professional interaction, it is the physiotherapist who is in power to define the setting, ask ques
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