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Search Results: 1 - 10 of 243 matches for " Jayesh Gala "
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Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]
Mark JS Miller, Komal Mehta, Sameer Kunte, Vidyanand Raut, Jayesh Gala, Ramesh Dhumale, Anil Shukla, Hemant Tupalli, Himanshu Parikh, Paul Bobrowski, Jayesh Chaudhary
Journal of Inflammation , 2005, DOI: 10.1186/1476-9255-2-11
Abstract: Patients (n = 107) with mild to moderate osteoarthritis of the knee were randomly assigned to one of 4 groups; high dose sierrasil (3 g/day), low dose sierrasil (2 g/day), low dose sierrasil (2 g/day) + cat's claw extract (100 mg/day) or placebo, administered for 8 weeks. Treatment was double blinded. Primary efficacy variables were WOMAC scores (A, B, C and total). Visual analog score (VAS) for pain, consumption of rescue medication (paracetamol), and tolerability were secondary variables. Safety measures included vital signs and laboratory-based assays.Ninety-one of the 107 patients successfully completed the protocol. All four groups showed improvement in WOMAC and VAS scores after 8 weeks (p < 0.001), in all 3 groups receiving sierrasil the magnitude of benefits were greater vs. placebo (WOMAC Total 38–43% vs. 27%) but this was not statistically significant. In reference to baseline values sierrasil treated groups had a considerably faster onset of benefits. Placebo-treated individuals failed to show significant benefits at 4 weeks (11% reduction in total WOMAC). In contrast, after 1 or 2 weeks of therapy all the sierrasil groups displayed significant reductions in WOMAC scores (p < 0.05) and at week 4 displayed a 38–43% improvement. VAS was significantly improved at 4 weeks in all groups (p < 0.001) but was significantly greater in all sierrasil groups compared to placebo (p < 0.05). Rescue medication use was 28-23% lower in the herbomineral combination and high dose sierrasil groups although not statistically different from placebo (P = 0.101 and P = 0.193, respectively). Tolerability was good for all groups, no serious adverse events were noted and safety parameters remained unchanged.The natural mineral supplement, sierrasil alone and in combination with a cat's claw extract, improved joint health and function within 1–2 weeks of treatment but significant benefits over placebo were not sustained, possibly due to rescue medication masking. Sierrasil may offer
Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]
Komal Mehta, Jayesh Gala, Surendra Bhasale, Sattayasheel Naik, Millind Modak, Harshad Thakur, Nivedita Deo, Mark JS Miller
BMC Complementary and Alternative Medicine , 2007, DOI: 10.1186/1472-6882-7-34
Abstract: Subjects (n = 95) were screened and randomized to receive glucosamine sulfate (n = 47, 1500 mg/day) or reparagen (n = 48, 1800 mg/day), a polyherbal consisting of 300 mg of vincaria (Uncaria guianensis) and 1500 mg of RNI 249 (Lepidium meyenii) administered orally, twice daily. Primary efficacy variable was response rate based on a 20% improvement in WOMAC pain scores. Additional outcomes were WOMAC scores for pain, stiffness and function, visual analog score (VAS) for pain, with assessments at 1, 2, 4, 6 and 8 weeks. Tolerability, investigator and subject global assessments and rescue medication consumption (paracetamol) were measured together with safety assessments including vital signs and laboratory based assays.Subject randomization was effective: age, gender and disease status distribution was similar in both groups. The response rates (20% reduction in WOMAC pain) were substantial for both glucosamine (89%) and reparagen (94%) and supported by investigator and subject assessments. Using related criteria response rates to reparagen were favorable when compared to glucosamine. Compared to baseline both treatments showed significant benefits in WOMAC and VAS outcomes within one week (P < 0.05), with a similar, progressive improvement over the course of the 8 week treatment protocol (45–62% reduction in WOMAC or VAS scores). Tolerability was excellent, no serious adverse events were noted and safety parameters were unchanged. Rescue medication use was significantly lower in the reparagen group (p < 0.01) at each assessment period. Serum IGF-1 levels were unaltered by treatments.Both reparagen and glucosamine sulfate produced substantial improvements in pain, stiffness and function in subjects with osteoarthritis. Response rates were high and the safety profile was excellent, with significantly less rescue medication use with reparagen. Reparagen represents a new natural productive alternative in the management of joint health.Current Controlled Trials ISRCTN2543
Simple Non-aqueous Fabrication Route for Oleic Acid Capped Luminescent Cadmium Sulphide Quantum Dots at Relatively Low Temperature  [PDF]
Jayesh Patel, Frej Mighri, Abdellah Ajji
Soft Nanoscience Letters (SNL) , 2011, DOI: 10.4236/snl.2011.13011
Abstract: In this communication, we report a simplistic non-aqueous fabrication route for oleic-acid capped luminescent cadmium sulphide quantum dots at low temperature. The resulting quantum dots, obtained without using any complicated reagents, are cubic in phase, monodispersed and have excellent optical properties. The simplicity of this fabrication route is also promising to develop other oleic acid-capped metal sulphide quantum dots at relatively low temperature.
Dois padr?es de política cambial: América Latina e Sudeste Asiático
Gala, Paulo;
Economia e Sociedade , 2007, DOI: 10.1590/S0104-06182007000100004
Abstract: some authors argue in favor of a real exchange rate targeting strategy for developing countries in what could be called a development approach to exchange rates. according to the argument, relatively undervalued exchange rates have been a key factor in most east and southeast asian successful growth strategies. following this so-called development approach, the objective of the paper is to compare the path of exchange rate levels in asia and latin america from 1970 to 1999. the work reviews some aspects of exchange rate management for some countries in those regions based on several case studies. it also presents an evolution of real exchange rate levels for a set of 20 countries based on world bank data and on an index of exchange rate distortion.
Capacidad de respuesta a emergencias epidémicas: recomendaciones para la autoevaluación nacional
Revista Panamericana de Salud Pública , 2005, DOI: 10.1590/S1020-49892005000700012
Abstract: communicable diseases that have appeared or reappeared in recent years have demonstrated their great potential for spreading and their capacity to overwhelm a country's resources, causing major emergencies. the recent sars epidemic showed that only health systems that have been strengthened and that have the response capacity for events of this kind will be able to handle future contingencies. governments have recognized the need to support initiatives to strengthen their countries' capacities in surveillance, prevention, and the control of emergencies caused by epidemics. this piece identifies essential components that will make it possible to guide the efforts of governments, with the support of the pan american health organization and other international organizations, toward achieving a common goal: establishing for countries warning and epidemic-emergency response systems that are appropriate and effective.
Quasi-geostrophic equations with initial data in Banach spaces of local measures
Sadek Gala
Electronic Journal of Differential Equations , 2005,
Abstract: This paper studies the well posedness of the initial value problem for the quasi-geostrophic type equations $$displaylines{ partial_{t}heta+u ablaheta+( -Delta) ^{gamma}heta =0 quad hbox{on }mathbb{R}^{d}imes] 0,+infty[cr heta( x,0) =heta_{0}(x), quad xinmathbb{R}^{d} }$$ where 0 less than $gammaleq 1$ is a fixed parameter and the velocity field $u=(u_{1},u_{2},dots,u_{d}) $ is divergence free; i.e., $ abla u=0)$. The initial data $heta_{0}$ is taken in Banach spaces of local measures (see text for the definition), such as Multipliers, Lorentz and Morrey-Campanato spaces. We will focus on the subcritical case 1/2 less than $gammaleq1$ and we analyse the well-posedness of the system in three basic spaces: $L^{d/r,infty}$, $dot {X}_{r}$ and $dot {M}^{p,d/r}$, when the solution is global for sufficiently small initial data. Furtheremore, we prove that the solution is actually smooth. Mild solutions are obtained in several spaces with the right homogeneity to allow the existence of self-similar solutions.
A remark on the regularity for the 3D Navier-Stokes equations in terms of the two components of the velocity
Sadek Gala
Electronic Journal of Differential Equations , 2009,
Abstract: In this note, we study the regularity of Leray-Hopf weak solutions to the Navier-Stokes equation, with the condition $$ abla (u_{1},u_{2},0) in L^{frac{2}{1-r}}(0,T; dot{mathcal{M}}_{2,3/r} (mathbb{R}^3) , $$ where $dot{mathcal{M}}_{2,3/r}(mathbb{R}^3)$ is the Morrey-Campanato space for $0
Regularity for 3D Navier-Stokes equations in terms of two components of the vorticity
Sadek Gala
Electronic Journal of Differential Equations , 2010,
Abstract: We establish regularity conditions for the 3D Navier-Stokes equation via two components of the vorticity vector. It is known that if a Leray-Hopf weak solution $u$ satisfies $$ ilde{omega}in L^{2/(2-r)}(0,T;L^{3/r}(mathbb{R}^3))quad hbox{with }0
Navier-Stokes equations and Banach spaces of local measures
Sadek Gala
Mathematics , 2005,
Abstract: This paper was removed by arXiv admin because it plagiarizes "Kozono, Hideo; Shimada, Yukihiro Bilinear estimates in homogeneous Triebel-Lizorkin spaces and the Navier-Stokes equations. Math. Nachr. 276 (2004), 63--74."
Solutions for the quasi-linear equations in multipliers space
Sadek Gala
Mathematics , 2005,
Abstract: This paper has been removed by arXiv administrators because it plagiarizes math.AP/0501483, "Quasilinear and Hessian equations of Lane-Emden type" by Nguyen Cong Phuc and Igor E. Verbitsky.
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