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Search Results: 1 - 10 of 11355 matches for " Jang-Sang Park "
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Incidence and Clinical Characteristics of Deep Vein Thrombosis (DVT) after Total Knee Arthroplasty (TKA) with DVT Chemoprophylaxis  [PDF]
Yong Sung Won, Mihyeong Kim, Kang Woong Jun, Woo Seok Nam, Sanghyun Ahn, Jeong-Kye Hwang, Sang-Dong Kim, Sun-Cheol Park, Sang Seob Yun, Won-Chul Lee, Jang-Sang Park, Jang Yong Kim
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.411064
Abstract: Objective: Deep vein thrombosis (DVT) after total knee arthroplasty (TKA) is very common and leading cause of death due to this procedure. The objective of this study was to investigate the incidence and clinical characteristics of DVT after TKA with DVT chemoprophylaxis. Methods: This is a prospective cohort study in single institution. The patients received postoperative DVT chemoprophylaxis (low molecular weight heparin (LMWH) or Fondaparinux), followed by duplex ultrasonography to check for DVT 1 - 2 weeks after TKA. The clinical characteristics were summarized and analysed by chi-square test and regression analysis. Results: Five hundred and thirty four patients were enrolled from January 2007 to December 2010. DVT chemoprophylaxis was administered in 524 (98.1%) of the 534 patients. DVT occurred in 9 subjects (1.69%); 8 subjects had DVT in the leg, and 1 subject had a pulmonary embolism. Among them, asymptomatic DVT was observed in 5 patients (0.94%). Univariate analysis showed that surgical methods (revision, P = 0.0007), body mass index (BMI) (>25, P = 0.0028), low platelet count (less than 150 × 103, P = 0.0219), time in the intensive care unit (ICU) (P < 0.0001), no administration of prophylactic LMWH (P = 0.0392), and a history of DVT (P < 0.0001) were significant risk factors of DVT. Conclusions: The incidence of DVT was 1.69% after TKA with prophylactic antithrombotic therapy. Revision surgery, BMI, low platelet count, time in ICU, absence of prophylactic LMWH and history of DVT were significant risk factors of DVT.
Perception-based Feature Weight Refinement for Boosting Image Retrieval Performance
Hun-Woo Yoo,Sang-Sung Park,Dong-Sik Jang
Asian Journal of Information Technology , 2012,
Abstract: Image similarity is often measured by computing the distance between two feature vectors. Unfortunately, the feature space cannot always capture the notion of similarity in human perception. Therefore, most current image retrieval systems use weights measuring the importance of each feature. In this paper new weight update rules are proposed for image retrieval purpose. In order to obtain optimal feature weights, database images are first divided into groups based on human perception, and then optimal feature weights for each database images are computed by using internal and outer query results. Experimental results show the proposed algorithm obtains more similar images to the query as the query process continues.
Effect of composite yogurt enriched with acacia fiber and Bifidobacterium lactis
Yang Won Min,Sang Un Park,Yeon Sil Jang,Young-Ho Kim
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i33.4563
Abstract: AIM: To investigate whether composite yogurt with acacia dietary fiber and Bifidobacterium lactis (B. lactis) has additive effects in irritable bowel syndrome (IBS). METHODS: A total of 130 patients were randomly allocated to consume, twice daily for 8 wk, either the composite yogurt or the control product. The composite yogurt contained acacia dietary fiber and high-dose B. lactis together with two classic yogurt starter cultures. Patients were evaluated using the visual analog scale via a structured questionnaire administered at baseline and after treatment. RESULTS: Improvements in bowel habit satisfaction and overall IBS symptoms from baseline were significantly higher in the test group than in the control group (27.16 vs 15.51, P = 0.010, 64.2 ± 17.0 vs 50.4 ± 20.5, P < 0.001; respectively). In constipation-predominant IBS, improvement in overall IBS symptoms was significantly higher in the test group than in the control group (72.4 ± 18.4 vs 50.0 ± 21.8, P < 0.001). In patients with diarrhea-predominant IBS, improvement in bowel habit satisfaction from baseline was significantly higher in the test group than in the control group (32.90 vs 7.81, P = 0.006). CONCLUSION: Our data suggest that composite yogurt enriched with acacia fiber and B. lactis has greater therapeutic effects in patients with IBS than standard yogurt.
Cutaneous T-Cell Lymphoma in Asians
Min Soo Jang,Dong Young Kang,Jong Bin Park,Sang Tae Kim
ISRN Dermatology , 2012, DOI: 10.5402/2012/575120
Cutaneous T-Cell Lymphoma in Asians
Min Soo Jang,Dong Young Kang,Jong Bin Park,Sang Tae Kim,Kee Suck Suh
ISRN Dermatology , 2012, DOI: 10.5402/2012/575120
Abstract: Cutaneous T-cell lymphoma describes a heterogeneous group of neoplasms of skin homing T cells that vary considerably in clinical presentation, histologic appearance, immunophenotype, and prognosis. This paper addresses the cutaneous T-cell lymphoma in Asians with respect to clinical-epidemiologic and histopathological features. Compared with Western countries, Asia usually has higher rates of cutaneous T-cell lymphomas such as extranodal NK/T-cell lymphoma, hydroa vacciniforme-like lymphoma, subcutaneous panniculitis T-cell lymphoma, and adult T-cell leukemia/lymphoma and lower rates of cutaneous B-cell lymphomas. Among many variants of mycosis fungoides, hypopigmented lesions, pityriasis lichenoides-like lesions, and ichthyosiform lesions are more prevalent in Asia than in the West. Adult T-cell leukemia/lymphoma is endemic in southwestern Japan especially in the Kyushu island. The clinicopathologic characteristics of cutaneous lymphoma vary according to geography, and this may be ascribed to genetic and environmental etiologic factors. 1. Introduction Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin lymphomas characterized by a dominant skin-homing T-cell clone with differing clinical presentations, histologic features, and therapeutic considerations. The reported incidence of these cancers has risen sharply over the past 15 years, which may be due to a combination of real increases in cases and improved access to and detection by medical practitioners [1]. The Korean dermatopathology research group reviewed nationwide collection of 80 cutaneous lymphoma cases in Korea. In this study, the most frequent cutaneous lymphoma was mycosis fungoides (42.5%), followed by anaplastic large cell lymphoma (19%), NK/T-cell lymphoma (15%), subcutaneous panniculitis-like T-cell lymphoma (11%), and cutaneous B-cell lymphomas (4%) [2]. Fujita et al. [3] reviewed 106 primary cutaneous lymphoma cases from a single Japanese medical center according to the revised 2008 WHO classification: cutaneous lymphomas comprised mycosis fungoides (52%), CD30 positive T-cell lymphoproliferative disorder (16%), adult T-cell leukemia/lymphoma (6%), NK/T-cell lymphoma (4%), subcutaneous panniculitis-like T-cell lymphoma (3%), and mature B-cell neoplasms (13%). As a whole, mature T-cell and NK-cell neoplasms were frequent (87%) because of the occurrence of adult T-cell leukemia/lymphoma and extranodal NK/T-cell lymphoma, nasal type, with less frequent occurrence of mature B-cell neoplasms (13%). Therefore, compared with Western countries, Korea and Japan usually had higher rates of
A Linear-Time Approximation of the Earth Mover's Distance
Min-Hee Jang,Sang-Wook Kim,Christos Faloutsos,Sunju Park
Computer Science , 2011,
Abstract: Color descriptors are one of the important features used in content-based image retrieval. The Dominant Color Descriptor (DCD) represents a few perceptually dominant colors in an image through color quantization. For image retrieval based on DCD, the earth mover's distance and the optimal color composition distance are proposed to measure the dissimilarity between two images. Although providing good retrieval results, both methods are too time-consuming to be used in a large image database. To solve the problem, we propose a new distance function that calculates an approximate earth mover's distance in linear time. To calculate the dissimilarity in linear time, the proposed approach employs the space-filling curve for multidimensional color space. To improve the accuracy, the proposed approach uses multiple curves and adjusts the color positions. As a result, our approach achieves order-of-magnitude time improvement but incurs small errors. We have performed extensive experiments to show the effectiveness and efficiency of the proposed approach. The results reveal that our approach achieves almost the same results with the EMD in linear time.
Integral T-Shaped Phantom-Dosimeter System to Measure Transverse and Longitudinal Dose Distributions Simultaneously for Stereotactic Radiosurgery Dosimetry
Wook Jae Yoo,Jinsoo Moon,Kyoung Won Jang,Ki-Tek Han,Sang Hun Shin,Dayeong Jeon,Jang-Yeon Park,Byung Gi Park,Bongsoo Lee
Sensors , 2012, DOI: 10.3390/s120506404
Abstract: A T-shaped fiber-optic phantom-dosimeter system was developed using square scintillating optical fibers, a lens system, and a CMOS image camera. Images of scintillating light were used to simultaneously measure the transverse and longitudinal distributions of absorbed dose of a 6 MV photon beam with field sizes of 1 × 1 and 3 × 3 cm2. Each optical fiber has a very small sensitive volume and the sensitive material is water equivalent. This allows the measurements of cross-beam profile as well as the percentage depth dose of small field sizes. In the case of transverse dose distribution, the measured beam profiles were gradually become uneven and the beam edge had a gentle slope with increasing depth of the PMMA phantom. In addition, the maximum dose values of longitudinal dose distribution for 6 MV photon beam with field sizes of 1 × 1 and 3 × 3 cm2 were found to be at a depth of approximately 15 mm and the percentage depth dose of both field sizes were nearly in agreement at the skin dose level. Based on the results of this study, it is anticipated that an all-in-one phantom-dosimeter can be developed to accurately measure beam profiles and dose distribution in a small irradiation fields prior to carrying out stereotactic radiosurgery.
Extended Star Clusters in the Remote Halo of the Intriguing Dwarf Galaxy NGC 6822
Narae Hwang,Myung Gyoon Lee,Jong Chul Lee,Won-Kee Park,Hong Soo Park,Sang Chul Kim,Jang-Hyun Park
Physics , 2011, DOI: 10.1088/0004-637X/738/1/58
Abstract: We present a study on four new star clusters discovered in the halo of the intriguing dwarf irregular galaxy NGC 6822 from a wide field survey covering 3 deg x 3 deg area carried out with MegaCam at Canada-France-Hawaii Telescope (CFHT). The star clusters have extended structures with half-light radii R_h ~ 7.5 -- 14.0 pc, larger than typical Galactic globular clusters and other known globular clusters in NGC 6822. The integrated colors and color magnitude diagrams (CMD) of resolved stars suggest that the new star clusters are 2 -- 10 Gyr old and relatively metal poor with Z=0.0001--0.004 based on the comparison with theoretical models. The projected distance of each star cluster from the galaxy center ranges from 10.7 arcmin (~ 1.5 kpc) to 77 arcmin (~ 11 kpc), far beyond the optical body of the galaxy. Interestingly, the new star clusters are aligned along the elongated old stellar halo of NGC 6822, which is almost perpendicular to the HI gas distribution where young stellar populations exist. We also find that the colors and half-light radii of the new clusters are correlated with the galactocentric distance: clusters farther from the galaxy center are larger and bluer than those closer to the galaxy center. We discuss the stellar structure and evolution of NGC 6822 implied by these new extended star clusters in the halo. We also discuss the current status of observational and theoretical understandings regarding the origin of extended star clusters in NGC 6822 and other galaxies.
Enhancement in electron transport and light emission efficiency of a Si nanocrystal light-emitting diode by a SiCN/SiC superlattice structure
Chul Huh, Bong K Kim, Byoung-Jun Park, Eun-Hye Jang and Sang-Hyeob Kim
Nanoscale Research Letters , 2013, DOI: 10.1186/1556-276X-8-14
Abstract: We report an enhancement in light emission efficiency of Si nanocrystal (NC) light-emitting diodes (LEDs) by employing 5.5 periods of SiCN/SiC superlattices (SLs). SiCN and SiC layers in SiCN/SiC SLs were designed by considering the optical bandgap to induce the uniform electron sheet parallel to the SL planes. The electrical property of Si NC LED with SiCN/SiC SLs was improved. In addition, light output power and wall-plug efficiency of the Si NC LED with SiCN/SiC SLs were also enhanced by 50% and 40%, respectively. This was attributed to both the formation of two-dimensional electron gas, i.e., uniform electron sheet parallel to the SiCN/SiC SL planes due to the conduction band offset between the SiCN layer and SiC layer, and an enhanced electron transport into the Si NCs due to a lower tunneling barrier height. We show here that the use of the SiCN/SiC SL structure can be very useful in realizing a highly efficient Si NC LED.
Elevated c-Src and c-Yes expression in malignant skin cancers
Jang Lee, Jae-Kyung Pyon, Dong Kim, Sang Lee, Hae Nam, Chul Kim, Sang Kang, Yoon Lee, Mi Park, Dong Jeong, Moon Cho
Journal of Experimental & Clinical Cancer Research , 2010, DOI: 10.1186/1756-9966-29-116
Abstract: To investigate the expression of c-Src and c-Yes in cutaneous carcinomas to include malignant melanoma (MM), squamous cell carcinoma (SCC) and basal cell carcinoma (BCC).We examined 6 normal skin tissues and 18 malignant skin tumor tissues using western blotting for the expression of c-Src and c-Yes. In another set, 16 specimens of MM, 16 SCCs and 16 BCCs were analyzed for the expression of c-Src and c-Yes using immunohistochemical staining.Western blotting showed that c-Src was expressed in all malignant skin tumors, but not in normal skin, while c-Yes was expressed in MM and SCC, but not in BCC and normal skin. Immunohistochemical staining results of c-Src and c-Yes in MM, SCC, and BCC mirrored those of the western blot analysis.c-Src, rather than c-Yes, plays a key role in the proliferation and progression of malignant skin cancers.Skin tumors have become one of the most common cancers in many countries, with rapid increasing incidence during the last half century. Nonmelanoma skin cancers including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) now make up more than one third of all cancers in the United States [1]. A large number of studies regarding the role of oncogenes and hormones, as well as environmental and predisposing factors, have been reported.Oncogenes, especially Src family kinases (SFKs), which are activated in colon and breast cancers, are drawing attention for their involvement in malignant melanoma (MM) [2]. SFKs are non-receptor tyrosine kinases that participate in variable cellular signal transduction pathways, with the capacity to trigger cancer with its continuous activation. SFKs are composed of 9 members, c-Src, c-Yes, Fyn, Lyn, Lck, Hck, Blk, Rgr, and Yrk. SFKs play integral roles in cancer development to include proliferation, survival, motility, invasiveness, metastasis, and angiogenesis. Most SFKs are primarily expressed from a hematopoietic cell origin, but c-Src, c-Yes, and Fyn are expressed at high levels by platelets
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