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Search Results: 1 - 10 of 302615 matches for " J. Wilson "
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Contemporary Issues in Protein Requirements and Consumption for Resistance Trained Athletes
Jacob Wilson, Gabriel J Wilson
Journal of the International Society of Sports Nutrition , 2006, DOI: 10.1186/1550-2783-3-1-7
Abstract: In recent years an explosion of information concerning sports nutrition has surfaced. This research has sought to analyze the optimization of whole food diets, as well as the efficacy of adding various supplements to the non supplemented diet. Particular subjects which have generated great debate and interest have concerned both the proper consumption of whole food and supplemental forms of proteins. In this context, a number of topics, such as protein requirements have been reexamined through extensive experimentation. In particular numerous variables have been identified which make the determination of protein requirements for resistance trained athletes particularly difficult [1]. Variables which have been demonstrated to affect the efficacy of any given protein intake include the timing of protein ingestion [1-4], the pattern of protein ingestion [1], the rate of digestion [5], the effect of added energy such as carbohydrates to a protein containing meal [6], and the quality of protein intake [7]. The interaction of these variables is absolutely essential for professionals attempting to prescribe a diet that optimizes muscular protein balance and indexes of performance in resistance trained athletes. As a result the need to consolidate this information has become critical. Therefore, the purpose of this review article is to critically examine these contemporary issues in protein consumption and how they interact with protein requirements for resistance trained athletes.In a recent Meta Analysis on protein requirements Rand et al. defined the protein requirement in healthy adults as "the continuing intake of dietary protein that is sufficient to achieve body nitrogen equilibrium (zero balance) in an initially healthy person of acceptable body composition at energy balance and under conditions of moderate physical activity...[8]" An individual's protein needs are assumed to have been met when the amount of nitrogen consumed is equal to the amount of nitrogen excre
The Role of Prolactin in the Evolution of Prostate Cancer  [PDF]
Maria Elena Hernandez, Michael J. Wilson
Open Journal of Urology (OJU) , 2012, DOI: 10.4236/oju.2012.223034
Abstract: Today there is significant information indicating an effect of prolactin on the prostate gland. It has been shown to be involved in mechanisms leading to the synthesis of some proteins such as PSA and cathepsin D, synthesis of citrate and accumulation of zinc. Also, at the behavioral level, prolactin is known to control some aspects of reproduction, including documentation on the physiology of the prostate and the possibility to trigger pathologies in this sex gland. Although the later still is not clear, there is a correlation between the level of prolactin and the presence of prostate pathologies. Thus, the aim of this review is to show how prolactin is involved in the progression of some pathologies of this male sexual gland.
Ion Exclusion at the Ice-Water Interface Differs from That at the Hydrate-Water Interface: Consequences for Methane Hydrate Exploration  [PDF]
P. W. Wilson, A. D. J. Haymet
International Journal of Geosciences (IJG) , 2017, DOI: 10.4236/ijg.2017.810070
Abstract:
When water-ice grows into salt solutions ion species are excluded by the ice differentially due to non-identical solubility in the ice lattice. This causes an electrical potential across the interface during the ice growth process, initially named the Workman Reynolds Freezing Potential, and may be one of the causes for lightning. However, by measuring the voltage between the ice and water, we have found that when tetrahydrofuran hydrate crystals are grown into salt solutions all ion species are excluded equally and the potential does not manifest. When considered together, this marked difference in ion exclusion scenarios may have ramifications for hydrate exploration because of the chlorine anomaly, which is often used as an indicator of the presence of hydrate reserves.
Insights from Genomics into Bacterial Pathogen Populations
Daniel J. Wilson
PLOS Pathogens , 2012, DOI: 10.1371/journal.ppat.1002874
Abstract: Bacterial pathogens impose a heavy burden of disease on human populations worldwide. The gravest threats are posed by highly virulent respiratory pathogens, enteric pathogens, and HIV-associated infections. Tuberculosis alone is responsible for the deaths of 1.5 million people annually. Treatment options for bacterial pathogens are being steadily eroded by the evolution and spread of drug resistance. However, population-level whole genome sequencing offers new hope in the fight against pathogenic bacteria. By providing insights into bacterial evolution and disease etiology, these approaches pave the way for novel interventions and therapeutic targets. Sequencing populations of bacteria across the whole genome provides unprecedented resolution to investigate (i) within-host evolution, (ii) transmission history, and (iii) population structure. Moreover, advances in rapid benchtop sequencing herald a new era of real-time genomics in which sequencing and analysis can be deployed within hours in response to rapidly changing public health emergencies. The purpose of this review is to highlight the transformative effect of population genomics on bacteriology, and to consider the prospects for answering abiding questions such as why bacteria cause disease.
Meta-analysis of SUMO1
Brian J Wilson
BMC Research Notes , 2008, DOI: 10.1186/1756-0500-1-60
Abstract: Oncomine [1] meta-analysis was performed as previously described [2,3]. Briefly, 15 multi-array studies were analyzed for common overlapping co-expressed genes of SUMO1, using muti-array studies within the Oncomine integrated cancer database. This technique gives insight into which pathways the searched gene (in this case SUMO1) are involved in, although it is impossible to tell if co-expressed gene products are complexed to SUMO1, act upstream of SUMO1 or downstream of SUMO1. Therefore, while limited, this technique is important for generating leads to assess both the pathways SUMO1 is important for, and regulation of SUMO1 itself.After meta-analysis there were over 400 consistently co-expressed genes at the cutoff of 3 studies (Additional File 1). Table 1 shows the genes with the higher cutoff of 4 studies. This high number may be expected as SUMO1 is a general factor and involved in many processes. I note that the archetype SUMO1-modified promyelocytic leukemia (PML) was co-expressed with SUMO1, acting as validation of the results [4]. While the Ubc9 conjugation enzyme was not found to be co-expressed many other ubiquitin-conjugating enzymes were (UBE2N, UBE4A, UBE2G1, UBE2V2, UBE2E1, UBE2D2, UBE2A, UBE1C, CUL4A), as was the SUMO1 activating enzyme subunit 2 (UBA2). Transcription factors shown to be modified by SUMO were also co-expressed, such as HIF1α, Rb, YY1, and SMAD4 [5-9]. Interestingly RARα is also co-expressed and while it has never been shown to be a target of SUMO1 the PML-RARα fusion has been shown to be a target of SUMO1 mediated degradation [10]. It would be interesting to investigate if RARα itself is a SUMO1 target. Also co-expressed is the NF-κB subunit RelA. While RelA also is not a proven target of SUMO1 NF-κB is regulated indirectly by SUMO1 modification of Iκ Kgamma/NEMO or IκB [11,12].A similar meta-analysis was attempted for SUMO2 and SUMO3. However, SUMO2 was not expressed to levels that allowed for meta-analysis, and the results of SUMO3
Estudo molecular dos alelos DI A/DI B e da banda 3-Memphis na popula o brasileira
B. Júnior Wilson
Revista Brasileira de Hematologia e Hemoterapia , 2002,
Abstract:
Differentials of the 2nd kind on a product surface
J. C. Wilson
International Journal of Mathematics and Mathematical Sciences , 1979, DOI: 10.1155/s0161171279000466
Abstract: This paper deals with the problems of representing an arbitrary double differential of the second kind, defined on a surface which is the topological product of two curves, in terms of the products of simple differentials of the second kind on the two curves. The curves are assumed to be non-singular and irreducible in a complex projective 2-space.
História da educa o musical e a experiência do canto orfe nico no Brasil
Wilson Lemos Júnior
Eccos Revista Científica , 2012,
Abstract: The teaching of music was always present during the periods of the history of the Brazilian education, but during the first half of the twentieth century, had a boom especially after the defense of the movement of educators of the new school, as the teachers Fernando de Azevedo and Anísio Teixeira and as the musician and conductor Heitor Villa-Lobos. In this article are discussed the process of recovery and the deployment of teaching music and chorus singing in the Brazilian schools. It tries to analyze the discourse of these characters, their ideas concerning music education, as well as their purposes, their advantages and their relations with the modern school.
The Male Genital Tube of the Amphizoid
J. W. Wilson
Psyche , 1928, DOI: 10.1155/1928/38082
Abstract:
The Male Genital Tube of Some of the Species of the Genus Scymnus (Coleoptera, Fam. Coccinellid )
J. W. Wilson
Psyche , 1927, DOI: 10.1155/1927/59839
Abstract:
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