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Agenesis of Internal Carotid Artery and Ischemic Stroke, One Case Report: A Review of Literature  [PDF]
Mapaga Nyangui Jennifer, M. Martinez, P. Desbordes, A. Diawara, R. Houeze, C. Laurent, J. Jacquin
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104947
Abstract:
Background: Agenesis of the internal carotid artery (ICA) is a rare anatomic variation of the cerebral circulation. A malfunction during the embryonic peri-od is at stake. It is very often asymptomatic and therefore discovered inci-dentally. Association with ischemic stroke is exceptional. Physiopathology is uncertain; the hypothesis of a blood flow reversal is reported in the literature. The diagnosis is based on the absence of a carotid canal as revealed by CT scans at skull base level with bone settings. Other non-invasive techniques, in-cluding echo-Doppler of the neck vessels, can now make the diagnosis. Objec-tive: Discuss the association between occurrence of an ischemic stroke in the left posterior sylvian territory and discovery of ipsilateral carotid agenesis. Case report: A 24-year-old female patient was prospectively recruited at DAX hospital center (France). Vascular risk factors involved active smoking of 8 pack-years and a combined estrogen/progestin contraceptive. Her family history included an uncle with heterozygote Factor V Leiden mutation. She presented a left upper limb sensorimotor deficit. Nuclear Magnetic Resonance Angiography (MRA) revealed a right superficial sylvian ischemic stroke asso-ciated with agenesis of the right internal carotid artery. CT scan at skull base level with bone settings showed absence of a right carotid canal, thus confirm-ing agenesis. An opinion was then requested for an arteriography which showed an operative polygon of Willis, a sylvian artery or middle cerebral ar-tery (MCA) irrigated by a very large right posterior communicating artery (PCOM) and the left anterior cerebral artery (ACA) supplied by the anterior communicating artery (ACOM), through the left carotid system. The right syl-vian territory where stroke occurred was therefore supplied by the functional vertebrobasilar system. ECG and four-day meticulous monitoring detected no cardiac rhythm disorders. Transesophageal echocardiography was normal. Blood tests results showed normal blood coagulation with glycohemoglobin level at 4.6%. Total cholesterol was 1.42 g/l including LDL-C at 0.82 g/l and HDL-C at 0.36 g/l; triglycerides levels were 1.23 g/l. VDRL-TPHA serodiagnosis for syphilis, and HIV serology were all negative. Thrombophilia testing was performed and showed absence of Factor V Leiden mutation. Homocyste-inemia level was normal. The patient was discharged under KARDEGIC 160 mg, one daily with home rehabilitation. Currently she’s doing well and no re-currence is observed.
Slow Spinal Cord Compression Inducing by Malignant Peripheral Nerve Sheath Tumors in Cotonou  [PDF]
D. Gnonlonfoun, C. Adjien, J. Nyangui Mapaga, L. Hode, G. Goudjinou, A. Sowanou, R. Domingo, P. Gnigone, G. Mambila, D. Affanou, P. H. Kouna Ndouongo, D. Houinato
Neuroscience & Medicine (NM) , 2018, DOI: 10.4236/nm.2018.91004
Abstract: MPNST is a very uncommon malignant type of neoplasm. It is often associated with neurofibromatosis type 1 (von Recklinghausen disease). It involves large anatomical regions, and thus takes on varied clinical presentations. However, bone location of MPNST, particularly in the spinal canal has been poorly described in the literature. We hereby report the case of a 29-year old young man with MPNST in the spinal canal. He presented a slow spinal cord compression confirmed by spinal MRI. MPNST was revealed through histologic and immune histochemical features after tumor resection.
Post-Stroke Depression at Teaching Hospital Center of Libreville  [PDF]
I. A. Camara, C. M. Coulibaly, N. Diouf Mbourou, P. M. Gnigone, G. A. G. Mambila Matsalou, A. Nsounda Mandzela, L. Oura, J. Nyangui Mapaga, U. D. Kombila, M. M. Moubecka, P. N. Kouna
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1105049
Abstract:
Introduction: Post-stroke depression occurs in a context of stroke characterized by sadness, loss of interest, feelings of guilt, loss of appetite, a feeling of tiredness, and a lack of concentration. Material and Methods: We conducted a descriptive cross-sectional study from January 1, 2013 to September 30, 2016. For the diagnosis of post-stroke depression, neuropsychological tests (DSM-IV and MADRS) were used. The collection approach was a maintenance survey followed by an examination. Results: From 153 stroke patients, 48.4% (n = 74) had post-stroke depression. Depressed mood was noted in 50.3% and 43.8% had a marked decrease in interest. 67.9% of these patients had a primary level of education. Widows had 4.2 times the risk of post-stroke depression, and married and retired patients were 3 times more likely than public servants. The occurrence of post-stroke depression was significantly related to the presence of motor deficit in our patients, p < 0.0001. Conclusion: These results suggest that the risk of developing depression after stroke increases with the motor deficit. The DSM-IV and MADRS scores remain neuropsychological examinations of choice for the diagnostic approach.
High-Field MRI Contribution in Tolosa-Hunt Syndrome (THS). Report of Two Cases and Review of Literature  [PDF]
Chérif Mohamadou Aidara, Philomène Kouna, Jennifer Nyangui Mapaga, Nfally Badji, Hamidou Deme, Abdoulaye Dione Diop, Abdoulaye Ndoye Diop, Sokhna Ba, El Hadj Niang
Open Journal of Radiology (OJRad) , 2018, DOI: 10.4236/ojrad.2018.83016
Abstract: Background: Tolosa Hunt Syndrome is an inflammatory condition of unknown etiology of the cavernous sinus and superior orbital fissure. Because of the difficulty in establishing histological evidence, his diagnosis is based on a set of arguments established by the International Headache Society. MRI allows indirect visualization of the granuloma and plays a key role in diagnosis and follow-up. Aim: To illustrate High-field MRI contribution in Tolosa-Hunt Syndrome (THS). Cases Presentation: Two patients, a 25-year-old female and a 40-year-old male were recruited in this retrospective case report study at the Radiology service of Fann University Hospital (Dakar Senegal). The first patient has been suffering from a right retro-orbital pain and diplopia for 2 months and the second from a painful oculomotor nerve palsy for 3 months. Blood tests, lumbar puncture, thyroid hormone levels and an infectious screen were done. Screening for converting enzymes, and serum antibodies were also done. They underwent a high field MRI (Siemens 1.5T) with T1, T2, FLAIR, T2*, diffusion B1000, TOF polygon, CISS 3D and T1 gadolinium sequences in the 3 planes space. No significant abnormality was detected in blood tests or CSF analysis. Screening for converting enzymes and serum antibodies screen were also negative. For each patient, MRI examinations showed a non tumoral thickening of the right cavernous sinus, suggesting a granulomatous involvement. Tolosa Hunt Syndrome was evoked firstly. They were put on corticotherapy at high doses with a spectacular regression of symptoms. The Criteria of the International Headache Society of THS were met in both patients. Conclusion: High-field MRI is a significant diagnostic tool in the assessment of painful ophthalmoplegia. It allows a direct visualization of the granuloma of the cavernous sinus and assesses its course throughout the disease.
Post-Stroke Epilepsy within a Teaching Hospital in Cotonou, Benin  [PDF]
Dieu Donné Gnonlonfoun, Constant Adjien, Mendinatou Agbetou, Thierry Adoukonou, Jennifer Mapaga, Gérard Goudjinou, Dismand Houinato
Neuroscience & Medicine (NM) , 2017, DOI: 10.4236/nm.2017.84007
Abstract: Seizures occurring after stroke are risk factors for the onset of ensuing epilepsy. However, the incidence of vascular epilepsy is low. The purpose of this study was to study vascular epilepsy features in a teaching university. It was a retrospective, descriptive and analytical study, conducted from 1st January 2015 to 31st December 2016 in Cotonou Teaching Hospital (CNHU-HKM), Benin. It involved 35 patients brought together through comprehensive sampling. Vascular epilepsy hospital attendance rate was 2%. There were simple partial seizures in 74.28% of cases while cerebral ischemia was recorded in 44.44% of patients. Neurological consultation after stroke occurrence was a protective factor against the occurrence of vascular epilepsy with significant p at 0.001.
New components of the mercury’s perihelion precession  [PDF]
J. J. Smulsky
Natural Science (NS) , 2011, DOI: 10.4236/ns.2011.34034
Abstract: The velocity of perihelion rotation of Mercury's orbit relatively motionless space is computed. It is prove that it coincides with that calculated by the Newtonian interaction of the planets and of the compound model of the Sun’s rotation.
Simple General Purpose Ion Beam Deceleration System Using a Single Electrode Lens  [PDF]
J. Lopes, J. Rocha
World Journal of Engineering and Technology (WJET) , 2015, DOI: 10.4236/wjet.2015.33014
Abstract: Ion beam deceleration properties of a newly developed low-energy ion beam implantation system were studied. The objective of this system was to produce general purpose low-energy (5 to 15 keV) implantations with high current beam of hundreds of μA level, providing the most wide implantation area possible and allowing continuously magnetic scanning of the beam over the sample(s). This paper describes the developed system installed in the high-current ion implanter at the Laboratory of Accelerators and Radiation Technologies of the Nuclear and Technological Cam-pus, Sacavém, Portugal (CTN).
Constraints on velocity anisotropy of spherical systems with separable augmented densities
J. An
Physics , 2011, DOI: 10.1088/0004-637X/736/2/151
Abstract: If the augmented density of a spherical anisotropic system is assumed to be multiplicatively separable to functions of the potential and the radius, the radial function, which can be completely specified by the behavior of the anisotropy parameter alone, also fixes the anisotropic ratios of every higher-order velocity moment. It is inferred from this that the non-negativity of the distribution function necessarily limits the allowed behaviors of the radial function. This restriction is translated into the constraints on the behavior of the anisotropy parameter. We find that not all radial variations of the anisotropy parameter satisfy these constraints and thus that there exist anisotropy profiles that cannot be consistent with any separable augmented density.
On the augmented density of a spherical anisotropic dynamic system
J. An
Physics , 2010, DOI: 10.1111/j.1365-2966.2011.18324.x
Abstract: This paper presents a set of new conditions on the augmented density of a spherical anisotropic system that is necessary for the underlying two-integral phase-space distribution function to be non-negative. In particular, it is shown that the partial derivatives of the Abel transformations of the augmented density must be non-negative. Applied for the separable augmented densities, this recovers the result of van Hese et al. (2011).
Fractional calculus, completely monotonic functions, a generalized Mittag-Leffler function and phase-space consistency of separable augmented densities
J. An
Physics , 2012,
Abstract: Under the separability assumption on the augmented density, a distribution function can be always constructed for a spherical population with the specified density and anisotropy profile. Then, a question arises, under what conditions the distribution constructed as such is non-negative everywhere in the entire accessible subvolume of the phase-space. We rediscover necessary conditions on the augmented density expressed with fractional calculus. The condition on the radius part R(r^2) -- whose logarithmic derivative is the anisotropy parameter -- is equivalent to R(1/w)/w being a completely monotonic function whereas the condition on the potential part is stated as its derivative up to the order not greater than 3/2-b being non-negative (where b is the central limiting value for the anisotropy parameter). We also derive the set of sufficient conditions on the separable augmented density for the non-negativity of the distribution, which generalizes the condition derived for the generalized Cuddeford system by Ciotti & Morganti to arbitrary separable systems. This is applied for the case when the anisotropy is parameterized by a monotonic function of the radius of Baes & Van Hese. The resulting criteria are found based on the complete monotonicity of generalized Mittag-Leffler functions.
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