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Search Results: 1 - 10 of 435148 matches for " J D Amin "
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HAEMOGRAM OF NIGERIAN MONGREL BITCH AT DIFFERENT STAGES OF THE REPRODUCTIVE CYCLE
G. D. Mshelia, J. D. Amin and S. U. R. Chaudhari
Pakistan Veterinary Journal , 2005,
Abstract: The haematologic parameters of the Nigerian Mongrel bitch were investigated at different stages of the reproductive cycle to determine their clinical values. Results showed that red blood cell (RBC) counts were highest during anoestrus, with a mean of 5.09 0.62 x 106/μL, while lowest values were recorded during pregnancy, the difference was significant (P<0.05). White blood cell (WBC) counts, packed cell volume (PCV) and haemoglobin concentration (Hb) showed an increasing pattern from anoestrus to proestrus and then decreased with transition from proestrus to oestrus. Total WBC counts were highest during dioestrus and almost twice the value recorded in pregnancy. It appears that WBC count may be used for pregnancy diagnosis in the Nigerian Mongrel bitch.
OESTRUS DETECTION IN THE NIGERIAN MONGREL BITCH: APPLICATION OF VAGINAL CYTOLOGY
G. D. Mshelia, J. D. Amin and S. U. R. Chaudhari
Pakistan Veterinary Journal , 2001,
Abstract: Vaginal smears from 45 multiparous Nigerian Mongrel bitches in proestrus (n=10), oestrus (n=22) and pregnancy (n=13) were examined, Differential cell count of exfoliated vaginal epithelial cells showed that the mean percentage of superficial cells was 95 in oestrus, 65.5 in proestrus and 15 in pregnant bitches. Oestrus smears were characterized by the presence of predominant superficial cells. The phase of predominance of superficial cells (>90%) was consistent with the phase of high vaginal mucus electrical resistance .measurements and sexual activity. It is therefore concluded that vaginal cytology can be applied in the detection of oestrus in the Nigerian Mongrel bitch.
Modeling the effects of stretch-dependent surfactant secretion on lung recruitment during variable ventilation  [PDF]
Samir D. Amin, Arnab Majumdar, Phil Alkana, Allan J. Walkey, George T. O’Connor, Béla Suki
Journal of Biomedical Science and Engineering (JBiSE) , 2013, DOI: 10.4236/jbise.2013.612A008
Abstract:

Variable ventilation (VV) is a novel strategy of ventilatory support that utilizes random variations in the delivered tidal volume (VT) to improve lung function. Since the stretch pattern during VV has been shown to increase surfactant release both in animals and cell culture, we hypothesized that there were combinations of PEEP and VT during VV that led to improved alveolar recruitment compared to conventional mechanical ventilation (CV). To test this hypothesis, we developed a computational model of stretch-induced surfactant release combined with abnormal alveolar mechanics of the injured lung under mechanical ventilation. We modeled the lung as a set of distinct acini with independent surfactant secretion and thus pressure-volume relationships. The rate of surfactant secretion was modulated by the stretch magnitude that an alveolus experienced per breath. Mechanical ventilation was simulated by delivering a prescribed VT at each breath. The fractional VT that each acinus received depended on its local compliance relative to the total system compliance. Regional variability in VT thus developed through feedback between stretch and surfactant release and coupling of regional VT to ventilator settings. The model allowed us to simulate patient-ventilator interactions over a wide range of PEEPs and VT

Single Core Hardware Modeling of Built-in-Self-Test for System on Chip Design
M.D. Mamun,M.S. Amin,J. Jalil
Research Journal of Applied Sciences, Engineering and Technology , 2012,
Abstract: This study describes a hardware modeling environment of built-in-self-test (BIST) for System on Chip (SOC) testing to ease the description, verification, simulation and hardware realization on Altera FLEX10K FPGA device. The very high speed hardware description language (VHDL) model defines a main block, which describe the BIST for SOC through a behavioral and structural description. The three modules test vector generator, circuit under test and response analyzer is connected using its structural description. 8-bit pseudorandom test vector generator is a linear feedback shift register circuit consists of D latches and XOR gates produces 255 different patterns of test vectors for CUT which consists of a 3 to 8 line decoder and a 4 bit adder circuit. In response analyzer, the multiple-input pattern compressor circuit is used to produce signature and a comparator circuit is used for signature analysis. The design is modularized and each module is modeled individually using hardware description language VHDL. This is followed by the timing analysis and circuit synthesis for the validation, functionality and performance of the designated circuit, which supports the practicality, advantages and effectiveness of the proposed hardware realization for the applications with a maximum clock frequency of 31.4 MHz.
Surface critical exponents for a three-dimensional modified spherical model
D. M. Danchev,J. G. Brankov,M. E. Amin
Physics , 1997, DOI: 10.1088/0305-4470/30/16/009
Abstract: A modified three-dimensional mean spherical model with a L-layer film geometry under Neumann-Neumann boundary conditions is considered. Two spherical fields are present in the model: a surface one fixes the mean square value of the spins at the boundaries at some $\rho > 0$, and a bulk one imposes the standard spherical constraint (the mean square value of the spins in the bulk equals one). The surface susceptibility $\chi_{1,1}$ has been evaluated exactly. For $\rho =1$ we find that $\chi_{1,1}$ is finite at the bulk critical temperature $T_c$, in contrast with the recently derived value $\gamma_{1,1}=1$ in the case of just one global spherical constraint. The result $\gamma_{1,1}=1$ is recovered only if $\rho =\rho_c= 2-(12 K_c)^{-1}$, where $K_c$ is the dimensionless critical coupling. When $\rho > \rho_c$, $\chi_{1,1}$ diverges exponentially as $T\to T_c^{+}$. An effective hamiltonian which leads to an exactly solvable model with $\gamma_{1,1}=2$, the value for the $n\to \infty $ limit of the corresponding O(n) model, is proposed too.
Decoding pooled RNAi screens by means of barcode tiling arrays
Michael Boettcher, Johannes Fredebohm, Amin Gholami, Yafit Hachmo, Iris Dotan, Dan Canaani, J?rg D Hoheisel
BMC Genomics , 2010, DOI: 10.1186/1471-2164-11-7
Abstract: We synthesized DNA microarrays with six overlapping 25 nt long tiling probes complementary to each unique 60 nt molecular barcode sequence associated with every shRNA expression construct. By analyzing dilution series of expression constructs we show how our approach allows quantification of shRNA abundance from a pool and how it clearly outperforms the commonly used analysis via the shRNA's half hairpin sequences. We further demonstrate how barcode tiling arrays can be used to predict anti-proliferative effects of individual shRNAs from pooled negative selection screens. Out of a pool of 305 shRNAs, we identified 28 candidate shRNAs to fully or partially impair the viability of the breast carcinoma cell line MDA-MB-231. Individual validation of a subset of eleven shRNA expression constructs with potential inhibitory, as well as non-inhibitory, effects on the cell line proliferation provides further evidence for the accuracy of the barcode tiling approach.In summary, we present an improved method for the rapid, quantitative and statistically robust analysis of pooled RNAi screens. Our experimental approach, coupled with commercially available lentiviral vector shRNA libraries, has the potential to greatly facilitate the discovery of putative targets for cancer therapy as well as sensitizers of drug toxicity.Breast cancer is caused by genetic and epigenetic alterations of the genome, resulting in changes in expression levels of certain genes [1]. In the past two decades, extensive efforts have been undertaken to characterize genes involved in breast cancer development. Genomic alterations and gene expression signatures associated with breast cancer and chemotherapy response have been identified [2-4]. However, genes that are neither mutated nor changed in their levels of expression may also play crucial roles in the progression of breast cancer. One way to identify such essential genes is the inhibition of their expression via RNA interference (RNAi) followed by the
Bacteria Flora Of The Anterior Genitalia Of The Sahelian Doe In Maiduguri-Borno State, Nigeria
Y M Bukar-Kolo, J D Amin, L T Zaria
Nigerian Veterinary Journal , 2007,
Abstract: The genital tract of animals especially the posterior part is known to harbour non-specific bacteria that are sometimes called the “normal flora”. Although the type of bacteria present and the role they play is not well understood, under stressful conditions they may cause disease (Hirsh, 1990). A variety of bacteria have been isolated from the genitalia of the doe and these include Staphylococci, Streptococci, Actinomyces, Pseudomonas, E. coli, Mycoplasma and Brucella species (Amin, 1988; Fasanya et al.,1987; Ababneh and Degefa,2006; Safiriyu et al., 2006). These organisms have been associated with disease conditions of the genitalia of animals. Adams, 1975 reported that isolation of pathogenic Staphylococci under normal and disease conditions of the genital tract revealed that they may be natural inhabitants of these organs but under conditions of stress such as following lambing, abortions etc they may cause metritis and infertility. Isolation of potentially pathogenic organisms from the normal genitalia of live and dead ewes has been reported previously (Hopwood, 1956; Amin 1988). Most of the reported cases were made from apparently healthy animals and in the absence of experimental infection; the true role of many of the isolates in reproductive disease has remained in doubt. Thus, this study was carried out to determine the ‘normal\' aerobic bacterial flora of the genitalia of apparently healthy sahelian does during different phases of the reproductive cycle.
Role of Single Qubit Decoherence Time in Adiabatic Quantum Computation
M. H. S. Amin,C. J. S. Truncik,D. V. Averin
Physics , 2008, DOI: 10.1103/PhysRevA.80.022303
Abstract: We have studied numerically the evolution of an adiabatic quantum computer in the presence of a Markovian ohmic environment by considering Ising spin glass systems with up to 20 qubits independently coupled to this environment via two conjugate degrees of freedom. The required computation time is demonstrated to be of the same order as that for an isolated system and is not limited by the single-qubit decoherence time $T_2^*$, even when the minimum gap is much smaller than the temperature and decoherence-induced level broadening. For small minimum gap, the system can be described by an effective two-state model coupled only longitudinally to environment.
Orientación sobre lactancia materna en un hospital para enfermedades diarreicas
Haider,R.; Islam,A.; Hamadani,J.; Amin,N. J.; Kabir,I.; Malek,M. A.; Mahalanabis,D.; Habte,D.;
Revista Panamericana de Salud Pública , 1997, DOI: 10.1590/S1020-49891997000500004
Abstract: lactation counsellors were trained to advise mothers of partially breast-fed infants who were admitted to hospital because of diarrhoea, so that they could start exclusive breast-feeding during their hospital stay. infants (n = 250) up to 12 weeks of age were randomized to intervention and control groups. mothers in the intervention group were individually advised by the counsellors while mothers in the control group received only routine group health education. during follow-up at home by the counsellors a week later, only the mothers in the intervention group were counselled. all the mothers were evaluated for infant feeding practices at home two weeks after discharge. among the 125 mother-infant pairs in each group, 60% of mothers in the intervention group were breast-feeding exclusively at discharge compared with only 6% in the control group (p < 0.001); two weeks later, these rates rose to 75% and 8% in the intervention and control groups, respectively (p < 0.001). however, 49% of mothers in the control group reverted back to bottle-feeding compared with 12% in the intervention group (p < 0.001). thus, individual counselling had a positive impact on mothers to start exclusive breast-feeding during hospitalization and to continue the practice at home. maternal and child health facilities should include lactation counselling as an integral part of their programmes to improve infant feeding practices.
Microencapsulation by Spray Drying of Vitamin A Palmitate from Oil to Powder and Its Application in Topical Delivery System  [PDF]
Avinash B. Gangurde, Purnima D. Amin
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2017, DOI: 10.4236/jeas.2017.71002
Abstract: Vitamin A palmitate (VAP) contains retinol and palmitic acid which is easily absorbed by body and widely used in skin care products. But, it is a hydrophobic and oxidation sensitive molecule which undergoes rapid degradation especially in an aqueous environment. The purpose of this study was to prepare microcapsules of VAP using combination maltodextrin and modified starches. Emulsion of VAP was prepared using cremophore RH 40 with Tween 80 in a homogenizer and formed emulsion was spray-dried. The spray process was optimized using a central composite design for two variables to obtain microcapsules with desirable characteristics. Microcapsules containing 30% of VAP were produced using different concentration of wall materials. The prepared microcapsules were evaluated for their physical, morphological, in-vitro drug release and SEM study. The results showed that obtained microcapsules are nearly spherical in shape with a particle size ranged from 1 to 12 μm. The drug content and encapsulation efficiency (53% - 63%) of different batches were found within acceptable range. These stabilized drug loaded microcapsules were incorporated into silicone cream based formulation for convenient topical application and evaluated for its physicochemical parameters. The drug release study showed 80.18% to 83.43% of drug release from VAP microcapsules while topical formulations prepared by VAP microcapsules showed 67.09% to 71.45% drug release at the end of 24 hrs. The formulations were kept for 3 months stability study as per ICH guidelines and found to be stable.
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