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Search Results: 1 - 10 of 463342 matches for " Ivo A; "
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Choices, dogmatisms and bets: justifying Peirce’s realism = Escolhas, dogmatismos e apostas: justificando o realismo de Peirce
Ibri, Ivo A.
Veritas , 2012,
Abstract: O eixo conceitual deste artigo constitui-se em uma reflex o sobre o realismo de Charles Peirce, buscando mostrá-lo como a base da qual se derivam muitas outras de suas doutrinas filosóficas. Na primeira parte do artigo, s o analisados os problemas colocados pelo clássico ensaio peirciano Quest es referentes a certas faculdades reivindicadas pelo homem, propondo extrair das consequências dessa análise as diretrizes de um realismo que gradualmente se torna mais radical na obra madura de Peirce. Tais consequências ser o consolidadas em sua fenomenologia, uma ciência que fundamentará a semiótica e uma concep o de simetria relacionada às categorias do autor. Essa simetria associada à sua epistemologia e ontologia será, a propósito, onipresente em todo o sistema filosófico peirciano. Na segunda parte do artigo, s o discutidos os conceitos de media o e representa o, também sob um viés realista, concluindo que esses conceitos n o podem ser coerentemente relacionados nas filosofias nominalistas. Nessas filosofias, encontram-se frequentemente consequências de alguma forma comprometidas com posturas dogmáticas e n o dialógicas, se confrontadas com uma análise do significado tal como proposto pelo pragmatismo clássico peirciano. The conceptual axis of this paper is a reflection on Charles Peirce’s realism, trying to show it as the ground from which many others of his philosophical doctrines are derived. In its first part, the paper analyses the problems posed by the classical Peircean paper Questions Concerning Certain Faculties Claimed for Man, proposing to extract from the consequences of this analysis the guidelines of a realism that gradually become more radical in Peirce’s mature work. Such consequences will be consolidated in his Phenomenology, a science that will ground Semiotics and a conception of symmetry related to Peirce’s categories. This symmetry regarding his epistemology and ontology will be, by the way, omnipresent in all Peircean philosophical system. The second part of the paper discusses the concepts of mediation and representation, also under a realistic background, concluding that these concepts cannot be coherently interlaced in nominalistic philosophies, in which is often found theoretical consequences somehow committed with dogmatic and no dialogic postures, in the sense of a meaning analysis proposed by the classical Peircean pragmatism.
Breast Core-Needle Biopsy in a Large Tertiary Oncologic Centre—1-Year Experience after the Introduction of the Method  [PDF]
Zoran Brni?, Maja Marinki?, Sa?a Schmidt, Ivo Pedi?i?, Karolina Bolan?a-?ulo
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.710075
Abstract: Ultrasound (US)-guided core-needle biopsy (CNB) is currently the procedure of choice for work-up of suspicious breast lesion. It is mainly used for evaluation of suspicious breast lesions categorized as BI-RADS 4 and 5 (Breast Imaging-Reporting and Data System). The conducted study included 56 female patients with detected suspicious breast leasions, and they underwent US-guided CNB during 1-year period with the aim to investigate the value of US-guided CNB of the breast in a tertiary-level large-volume oncological centre setting with respect of indications, technical adequacy and safety. 2 patients who entered the study were previously diagnosed as BIRADS 2, 3 patients as BIRADS 3, 18 patients as BIRADS 4 and 33 patients as BIRADS 5. In 14 patients with BC (breast cancer), both FNA (fine-needle aspiration) and CNB were performed, and the malignancy was accurately diagnosed by cytology in 9 patients, confirmed by subsequent CNB in all of them. ADH (atypical ductal hyperplasia) was initialy diagnosed by FNA in 5 patients, and in 2 of them, BC was initialy missed by FNA, but deteced by CNB. As it is known, the cytology has lower sensitivity for detection of BC than hystology, with false-negative rate ranging from 2.5% to 17.9%. In our material, 18.7% of carcinomas were initialy left undetected by FNAC, and subsequently confirmed by CNB. All confirmed carcinomas were correctly suspected on imaging, and categorized as BI-RADS 4 or 5, while all BI-RADS 2 and 3 findings were confirmed as benign on hystology. False-positive rate of imaging was 8%. An average number of 4 tissue cores (range: 2 - 7) was taken in our experience if good quality of the first 3 core was achieved, and there was no consistent reason to proceed with sampling.
Modelos de remunera??o e rendibilidade nas empresas familiares portuguesas
Pereira,Ivo; Esperan?a,José Paulo;
Revista Portuguesa e Brasileira de Gest?o , 2009,
Abstract: variable compensation is usually supported by the belief that it is efficient in interest alignment between principals and agents. in public corporations, in particular, the solution of agency problems lies with the introduction of a variable compensation model, including stock options. this issue is still ignored in firms where the principal is also in charge of management. the empirical study of this phenomenon is exiguous and the background theory has suffered developments, like the introduction of family firms? agency problems. this study is based on a comparative analysis of 102 of the biggest portuguese firms and confirms the larger use of variable compensation by public firms, but shows also that the older family firms tend to use more variable compensation.
Modelos de remunera o e rendibilidade nas empresas familiares portuguesas Modelos de remuneración y rentabilidad en las empresas familiares portuguesas Compensation and profitability in Portuguese family firms
Ivo Pereira,José Paulo Esperan?a
Revista Portuguesa e Brasileira de Gest?o , 2009,
Abstract: A remunera o variável é habitualmente justificada pelo seu efeito de alinhamento dos interesses dos gestores e dos accionistas. Nas empresas de capitais dispersos, em particular, a resolu o de problemas de agência passaria pela introdu o de um modelo de remunera o variável, incluindo stock options. Este aspecto é ainda ignorado, no ambito das empresas em que os proprietários também exercem a gest o. N o só é exíguo o estudo empírico deste fenómeno, como a própria fundamenta o teórica tem vindo a sofrer desenvolvimentos profundos, com a inclus o dos problemas de agência específicos das empresas familiares. Este estudo baseia-se na análise comparativa de 102 das maiores empresas portuguesas e confirma a maior propens o para a remunera o variável por parte das empresas de capitais dispersos, e que só as empresas familiares mais antigas beneficiam com a adop o de modelos de remunera o variável. La retribución variable se justifica normalmente por el efecto de alinear los intereses de los directivos y accionistas. En las empresas de capitales dispersos, en particular, la resolución de los problemas de la agencia pasaría por la introducción de un modelo de remuneración variable, incluidas las opciones sobre acciones (stock options). Esto es ignorado en el contexto de las empresas donde los propietarios también tienen la gestión. No solo es escaso el estudio empírico de este fenómeno, como la base teórica ha sido objeto de profunda evolución, con la inclusión de problemas de agencia específicos de las empresas familiares. Este estudio se basa en el análisis comparativo de las 102 mayores empresas portuguesas y confirma la mayor propensión a pagar una remuneración variable por las empresas de capitales dispersos, y que sólo las más antiguas empresas familiares se benefician de la adopción de modelos de remuneración variable. Variable compensation is usually supported by the belief that it is efficient in interest alignment between principals and agents. In public corporations, in particular, the solution of agency problems lies with the introduction of a variable compensation model, including stock options. This issue is still ignored in firms where the principal is also in charge of management. The empirical study of this phenomenon is exiguous and the background theory has suffered developments, like the introduction of family firms’ agency problems. This study is based on a comparative analysis of 102 of the biggest Portuguese firms and confirms the larger use of variable compensation by public firms, but shows also that the older family firms tend t
A Process for Extracting Non-Taxonomic Relationships of Ontologies from Text  [PDF]
Ivo Serra, Rosario Girardi
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.34014
Abstract: Manual construction of ontologies by domain experts and knowledge engineers is an expensive and time consuming task so, automatic and/or semiautomatic approaches are needed. Ontology learning looks for identifying ontology elements like non-taxonomic relationships from information sources. These relationships correspond to slots in a frame-based ontology. This article proposes an initial process for semiautomatic extraction of non-taxonomic relationships of ontologies from textual sources. It uses Natural Language Processing (NLP) techniques to identify good candidates of non-taxonomic relationships and a data mining technique to suggest their possible best level in the ontology hierarchy. Once the extraction of these relationships is essentially a retrieval task, the metrics of this field like recall, precision and f-measure are used to perform evaluation.
The Limits of the Balanced Scorecard  [PDF]
Ivo Hristov, Antonio Chirico
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.411004
Abstract:
Our research focuses on the limits of the Balanced Scorecard. The aim of the work is to provide a basis for in-depth study on the limits of the balanced scorecard. According to Tranfield et al. (2003) [1] we are tackling the topic through a systematic review of the literature. We reviewed articles published in 48 journals, in 3 different subject area of Academic Journal Guide (ABS) 2015: 27 Accounting journals, 17 General Management and Employment Study journals and 4 Strategy journals. This ensured an academic quality of these articles and for each subject area we chose amongst some of the 3, 4 and 4* journals. The contributions of research to the field and the lessons learned from these studies are discussed. Knowledge gaps in existing balanced scorecard research are identified, leading to consideration of several ideas for future research.
MotifAdjuster: a tool for computational reassessment of transcription factor binding site annotations
Jens Keilwagen, Jan Baumbach, Thomas A Kohl, Ivo Grosse
Genome Biology , 2009, DOI: 10.1186/gb-2009-10-5-r46
Abstract: The regulation of gene expression involves a complex system of interacting components in all living organisms [1] and is of fundamental interest, for instance, for cell maintenance and development. One level of regulation is realized by DNA-binding transcription factors (TFs). The DNA-binding domain of a TF is capable of recognizing specific binding sites (BSs) in the promoter regions of its target genes [2]. Binding of a TF can induce (activator) or inhibit (repressor) the transcription of its target genes. The general ability to control a target gene may depend on the BS itself, its strand orientation, and its position with respect to the transcription start site. If other BSs are present, the ability of a TF to bind the DNA may additionally depend on strand orientations and positions of these BSs.One important prerequisite for research on gene regulation is the reliable annotation of BSs. The approximate regions on the double-stranded DNA sequence bound by TFs can be determined by wet-lab experiments such as electrophoretic mobility shift assays (EMSAs) [3], DNAse footprinting [4], enzyme-linked immunosorbent assay (ELISA) [5,6], ChIP-chip [7], or mutations of the putative BS and subsequent expression studies. Because TFs bind to double-stranded DNA, the strand annotations of nonpalindromic BSs in the databases are either missing or added, based on manual inspection or predictions from bioinformatics tools such as MEME [8], Gibbs Sampler [9,10], Improbizer [11], SeSiMCMC [12], or A-GLAM [13].After wet-lab identification, data about transcriptional gene regulatory interactions, including the annotated BSs, are published in the scientific literature. Subsequently, these data are extracted by curation teams and manually entered into databases on transcriptional gene regulation such as CoryneRegNet [14], PRODORIC [15], or RegulonDB [16] for prokaryotes, and AGRIS [17], AthaMap [18], CTCFBSDB [19], JASPAR [20], OregAnno [21], SCPD [22], TRANSFAC [23], TRED [24], or TR
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Jo A Helmuth, Grégory Paul, Ivo F Sbalzarini
BMC Bioinformatics , 2010, DOI: 10.1186/1471-2105-11-372
Abstract: We first reinvestigate the classical co-localization measure in the context of spatial point pattern analysis. This allows us to unravel the set of implicit assumptions inherent to this measure and to identify potential confounding factors commonly ignored. We generalize object-based co-localization analysis to a statistical framework involving spatial point processes. In this framework, interactions are understood as position co-dependencies in the observed localization patterns. The framework is based on a model of effective pairwise interaction potentials and the specification of a null hypothesis for the expected pattern in the absence of interaction. Inferred interaction potentials thus reflect all significant effects that are not explained by the null hypothesis. Our model enables the use of a wealth of well-known statistical methods for analyzing experimental data, as demonstrated on synthetic data and in a case study considering virus entry into live cells. We show that the classical co-localization measure typically under-exploits the information contained in our data.We establish a connection between co-localization and spatial interaction of sub-cellular structures by formulating the object-based interaction analysis problem in a spatial statistics framework based on nearest-neighbor distance distributions. We provide generic procedures for inferring interaction strengths and quantifying their relative statistical significance from sets of discrete objects as provided by image analysis methods. Within our framework, an interaction potential can either refer to a phenomenological or a mechanistic model of a physico-chemical interaction process. This increased flexibility in designing and testing different hypothetical interaction models can be used to quantify the parameters of a specific interaction model or may catalyze the discovery of functional relations.A general biological principle states that cellular function results from the combined interaction
Comportamento migratório da lagosta Panulirus argus (Latreille), em frente ao Estado do Ceará, Brasil
Fonteles-Filho, Antonio Adauto;Ivo, Carlos Tassito Corrêa;
Boletim do Instituto Oceanográfico , 1980, DOI: 10.1590/S0373-55241980000200035
Abstract: tagging experiments have been used to study the migratory behaviour of the spiny lobster panulirus argus (latreille), off ceará state, brazil. an analysis based on vectorial theory has provided the calculation of the coefficient of directional dispersion ( v), the coefficient of randon disperson (a2 ) and the centre of density, by quarters of the year. the lobsters were found to engage in breeding migration in the second quarter, when there is a low random dispersion and in feeding migration in the third and fourth quarters, when there is high randon dispersion. the spawning areas are located in offshore regions and the lobsters reach them by moving seawardly, from positions occupied nearer the cost, in the fourth quarter.
Comportamento migratório da lagosta Panulirus argus (Latreille), em frente ao Estado do Ceará, Brasil
Fonteles-Filho, Antonio Adauto;Ivo, Carlos Tassito Corrêa;
Brazilian Journal of Oceanography , 1980, DOI: 10.1590/S1679-87591980000200035
Abstract: tagging experiments have been used to study the migratory behaviour of the spiny lobster panulirus argus (latreille), off ceará state, brazil. an analysis based on vectorial theory has provided the calculation of the coefficient of directional dispersion ( v), the coefficient of randon disperson (a2 ) and the centre of density, by quarters of the year. the lobsters were found to engage in breeding migration in the second quarter, when there is a low random dispersion and in feeding migration in the third and fourth quarters, when there is high randon dispersion. the spawning areas are located in offshore regions and the lobsters reach them by moving seawardly, from positions occupied nearer the cost, in the fourth quarter.
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