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Search Results: 1 - 10 of 462637 matches for " Isabella A. Quakyi "
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Characterization of malaria transmission by vector populations for improved interventions during the dry season in the Kpone-on-Sea area of coastal Ghana
Tchouassi David P,Quakyi Isabella A,Addison Ebenezer A,Bosompem Kwabena M
Parasites & Vectors , 2012, DOI: 10.1186/1756-3305-5-212
Abstract: Background Malaria is a major public health problem in Ghana. We present a site-specific entomological study of malaria vectors and transmission indices as part of an effort to develop a site for the testing of improved control strategies including possible vaccine trials. Methods Pyrethrum spray catches (PSC), and indoor and outdoor human landing collections of adult female anopheline mosquitoes were carried out over a six-month period (November 2005 - April 2006) at Kpone-on-Sea, a fishing village in southern Ghana. These were morphologically identified to species level and sibling species of the Anopheles gambiae complex further characterized by the polymerase chain reaction (PCR). Enzyme-linked immunosorbent assay was used to detect Plasmodium falciparum mosquito infectivity and host blood meal sources. Parity rate was examined based on dilatation of ovarian tracheoles following dissection. Results Of the 1233 Anopheles mosquitoes collected, An. gambiae s.l. was predominant (99.5%), followed by An. funestus (0.4%) and An. pharoensis (0.1%). All An. gambiae s.l. examined (480) were identified as An. gambiae s.s. with a majority of M molecular form (98.2%) and only 1.8% S form with no record of M/S hybrid. A significantly higher proportion of anophelines were observed outdoors relative to indoors (χ2 = 159.34, df = 1, p < 0.0000). Only An. gambiae M molecular form contributed to transmission with a high degree of anthropophily, parity rate and an estimated entomological inoculation rate (EIR) of 62.1 infective bites/person/year. The Majority of the infective bites occurred outdoors after 09.00 pm reaching peaks between 12.00-01.00 am and 03.00-04.00 am. Conclusion Anopheles gambiae M molecular form is responsible for maintaining the status quo of malaria in the surveyed site during the study period. The findings provide a baseline for evidence-based planning and implementation of improved malaria interventions. The plasticity observed in biting patterns especially the combined outdoor and early biting behavior of the vector may undermine the success of insecticide-based strategies using insecticide treated nets (ITN) and indoor residual spray (IRS). As such, novel or improved vector interventions should be informed by the local malaria epidemiology data as it relates to vector behavior.
The Antibody Response of Pregnant Cameroonian Women to VAR2CSA ID1-ID2a, a Small Recombinant Protein Containing the CSA-Binding Site
Anna Babakhanyan, Rose G. F. Leke, Ali Salanti, Naveen Bobbili, Philomina Gwanmesia, Robert J. I. Leke, Isabella A. Quakyi, John J. Chen, Diane Wallace Taylor
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088173
Abstract: In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally acquire antibodies to ID1-ID2a and if antibodies to ID1-ID2a correlate with absence of placental malaria at delivery. Antibody levels to full-length VAR2CSA and ID1-ID2a were measured in plasma samples from 745 pregnant Cameroonian women, 144 Cameroonian men, and 66 US subjects. IgM levels and IgG avidity to ID1-ID2a were also determined. As expected, antibodies to ID1-ID2a were absent in US controls. Although pregnant Cameroonian women developed increasing levels of antibodies to full-length VAR2CSA during pregnancy, no increase in either IgM or IgG to ID1-ID2a was observed. Surprisingly, no differences in antibody levels to ID1-ID2a were detected between Cameroonian men and pregnant women. For example, in rural settings only 8–9% of males had antibodies to full-length VAR2CSA, but 90–96% had antibodies to ID1-ID2a. In addition, no significant difference in the avidity of IgG to ID1-ID2a was found between pregnant women and Cameroonian men, and no correlation between antibody levels at delivery and absence of placental malaria was found. Thus, the response to ID1-ID2a was not pregnancy specific, but predominantly against cross-reactivity epitopes, which may have been induced by other PfEMP1 antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a.
Profiles of HIV-Affected Households in Ghana  [PDF]
Amos Laar, Daniel Fiaveh, Matilda Laar, Sandra Boatemaa, James Abugri, Richard Amenyah, Kyeremeh Atuahene, Andrew Anthony Adjei, Isabella Quakyi, Angela El-Adas
Health (Health) , 2014, DOI: 10.4236/health.2014.615235
Abstract: Background: To contribute to a fuller appreciation of Ghana’s HIV epidemic, this paper presents various profiles of the Ghanaian HIV-affected household. To comprehensively tackle the HIV epidemic in Ghana, the profiles would provide stakeholders with ready information for policy formulation. Methods: We used data from a nationally representative survey that measured livelihood activities, household asset wealth, household composition, health, and nutrition variables of 1745 HIV-affected households. From these emerged various profiles. Results: About 50% of the households are headed by females. Households headed by men have an average size of three members, compared to two for female-headed households. There are far more AIDS widows than widowers. The annual death rate among the surveyed households was about 1000 per 100,000-households. Relatively more deaths occurred in male-headed households. Two-thirds of the households were asset poor. Various coping strategies were instituted by the households in reaction to threat of food insecurity. The national prevalence of chronic energy deficiency is 16%. Conclusions: Our data show that age of household head, hosting of a chronically ill member, and average size of household differed by sex of household head. The annual death rate of 1000 per 100,000 households is very high.
Study Paper on Test Case generation for GUI Based Testing
A. Isabella,Emi Retna
Computer Science , 2012,
Abstract: With the advent of WWW and outburst in technology and software development, testing the software became a major concern. Due to the importance of the testing phase in a software development life cycle, testing has been divided into graphical user interface (GUI) based testing, logical testing, integration testing, etc.GUI Testing has become very important as it provides more sophisticated way to interact with the software. The complexity of testing GUI increased over time. The testing needs to be performed in a way that it provides effectiveness, efficiency, increased fault detection rate and good path coverage. To cover all use cases and to provide testing for all possible (success/failure) scenarios the length of the test sequence is considered important. Intent of this paper is to study some techniques used for test case generation and process for various GUI based software applications.
I confini della lettera. Pratiche epistolari e reti di comunicazione nell'Italia tardomedievale
Isabella Lazzarini (a cura di)
Reti Medievali Rivista , 2009,
Abstract: Atti della giornata di studi, Isernia, 9 maggio 2008. Proceedings of the study day, Isernia, 9 maggio 2008.
Representaciones Sociales de los Chilenos Acerca del 11 de Septiembre de 1973 y su Relación con la Convivencia Cotidiana y con la Identidad Chilena
Prado,María Isabella; Krause,Mariane;
Psykhe (Santiago) , 2004, DOI: 10.4067/S0718-22282004000200005
Abstract: september eleventh of 1973 is a very important historical date in chile. its standing in social life shows that by talking about social representations and today effects of september eleventh, we are talking about a specific moment of a current process. the theory of social representations was chosen for this project, understanding those as a collective, intersubjective construction, made possible through communication and becoming a way of interpreting and understanding reality (jodelet, 1984; wagner & elejabarrieta, 1994). the valorative, affective, symbolic and cognitive elements through which september eleventh is looked at, help building intersubjective realities that influence not only the way people relate to each other, affecting how they live together, but also influence the way of being and feeling chilean.
Representaciones Sociales de los Chilenos Acerca del 11 de Septiembre de 1973 y su Relación con la Convivencia Cotidiana y con la Identidad Chilena Chileans Social Representations About September Eleventh 1973 and its Relationship With Daily Living Together and Chilean Identity
María Isabella Prado,Mariane Krause
Psykhe (Santiago) , 2004,
Abstract: El 11 de septiembre de 1973 es una fecha de profunda significación en Chile. Su vigencia muestra que, al hablar de las representaciones sociales y los efectos actuales del 11, se está haciendo referencia a contenidos de un momento específico dentro de un proceso. Se abordó este trabajo desde la perspectiva teórica de las representaciones sociales, entendidas como una elaboración colectiva, intersubjetiva, posible a través de la comunicación y que se constituye en una manera de interpretar y aprehender la realidad cotidiana (Jodelet, 1984; Wagner & Elejabarrieta, 1994). Los elementos valorativos, afectivos, simbólicos y cognitivos con que se mira el 11, construyen realidades intersubjetivas que influyen en el modo de relacionarse de las personas, afectando la convivencia cotidiana e interviniendo en el modo de ser y de sentirse chileno. September eleventh of 1973 is a very important historical date in Chile. Its standing in social life shows that by talking about social representations and today effects of September eleventh, we are talking about a specific moment of a current process. The theory of social representations was chosen for this project, understanding those as a collective, intersubjective construction, made possible through communication and becoming a way of interpreting and understanding reality (Jodelet, 1984; Wagner & Elejabarrieta, 1994). The valorative, affective, symbolic and cognitive elements through which September eleventh is looked at, help building intersubjective realities that influence not only the way people relate to each other, affecting how they live together, but also influence the way of being and feeling Chilean.
School Violence as a Cause of Non-Peaceful Coexistence in Public Secondary Schools in Nairobi, Kenya  [PDF]
Olivia A. Opere, Isabella Kamere, Violet Wawire
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.79010
Abstract: Public secondary schools in Kenya have in the recent past experienced several unrests, a situation that has threatened the fabric that holds them together. For quite some time, there have been reported cases of arson attacks and other forms of school violence in public secondary schools in Kenya. The incidences of violence have resulted into injuries, loss of property and sometimes loss of lives. In spite of the tough measures meted out on the students who are found to be involved in such acts, not much has been achieved. Using data collected from a sample of 341 public secondary school students and 88 teachers drawn from a survey of 22 public secondary schools in Nairobi County, the paper has identified various forms, causes and perpetrators of violence in public secondary schools in Kenya. The paper has argued that the earlier the perpetrators, forms and causes of violence are identified and mitigated through acquisition of knowledge and skills on peace education, the more likely the risks will be eliminated to enable the learners to embrace peace values and peaceful coexistence in the community. The study found out that school violence occurs in the form of verbal abuses, physical fights, bullying, and arson attacks. It also emerged that violence occurred during meals, social events and on the way going home from school and that the main perpetrators included classmates, prefects and even teachers. Key contributing factors to school violence were competition for resources, political differences, sexual discrimination and non-tolerance to cultural diversity. The paper concluded that the more effectively the peace values are inculcated into students in public secondary schools, the better well behaved the students are likely to become; hence no or limited school unrests will be experienced.
Dental Apps for Smartphones: New Way of Providing Services and Education  [PDF]
Isabella Marques Faria, Mariana Coutinho Sancas, Andréa Vaz Braga Pintor, Laura Salignac Guimar?es Primo
Creative Education (CE) , 2018, DOI: 10.4236/ce.2018.95050
Abstract: Objective: To review the literature about dental applications (DAPP) for smartphones (SP) and search/describe DAPP available in Portuguese, in 3 operating systems. Methods: Aiming the review, the terms “smartphones”, “app” and “dentistry” were searched in the databases Pubmed, Virtual Health Library (BVS) and Google Scholar. Based on the review results, DAPP were searched for teaching and learning (TL), clinical practice (CP), patient orientation (PO) and professional update (PU), in Portuguese, in the Android, iOS and Windows systems. In 3 SP (iPhone 5S with iOS 9.3.5; Samsung Galaxy A5 6 2016 with Android; Microsoft-RM-1109 with Windows Phone 8.1 Update2) the term “dentistry” was inserted in APP searches. Results: Forty-three papers were included in the review and 215 DAPP were selected: 120 on Android, 90 on iOS, and 5 on Windows. DAPP were classified according to the focus in: CP (n = 99); PO (n = 6); CP/PO (n = 64); TL/CP (n = 6); TL (n = 38); TL/CP/PO (n = 1) And PU and TL (n = 1). The majority of the DAPP was not validated by any Dental institution (93.02%) and was no cost way for users (81.86%), although only 58.14 were updated. Conclusion: Most of the papers showed as main focus CP, TL and PO. The DAPP available in Portuguese for Dentistry were mostly developed for clinical practice, with a lack of
Trust between Boundary-Spanning Agents: The Role of Relational Competencies  [PDF]
Isabella Hatak, Dietmar Roessl
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.33001
Abstract:

Against the background of principal-agent and transaction-cost theoretical considerations, this study addresses the question whether relational competencies relate to trust within cooperative relationships, taking into account also situational and personal factors. In its conclusion, the study presents an experimentally confirmed model (n = 282) that shows the strong causal relationship between relational competencies and trust allowing boundary-spanning agents to exert influence on the development and maintenance of complex cooperative relationships characterized by long-term objectives.

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