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Search Results: 1 - 10 of 150040 matches for " Iris B.;Gonzalez "
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Biology of Bonagota cranaodes (Meyrick) (Lepidoptera: Tortricidae) on seven natural foods
Bentancourt, Carlos M.;Scatoni, Iris B.;Gonzalez, Alvaro;Franco, Jorge;
Neotropical Entomology , 2004, DOI: 10.1590/S1519-566X2004000300004
Abstract: the effect of seven natural diets on the development and reproduction of bonagota cranaodes (meyrick) was evaluated under laboratory conditions. the experiments were carried out at the temperature of 23 ± 1oc, with 70 ± 10% of rh and a photoperiod of 16:8h (l:d). the larvae were reared on apple, grapevine and honeysuckle (lonicera japonica). on the first two foods three types of diet were used: spring leaves, summer leaves and fruits. the number of instars varied from five to seven. the larvae reared on apple leaves had, in general, fewer instars than those reared on grapevine and honeysuckle leaves. the duration of larval development differed between diets. the larvae reared on spring apple leaves showed the shortest duration, and those on fruit the longest. the larvae survival was lower on fruit than on leaves, and on apples it was particularly low (17.8%). the female pupae reared on honeysuckle were heavier than those reared on the other diets. the cycle from the egg to the emergence of adults varied between 41 days on spring apple leaves and 60 days on apples. the females reared on honeysuckle and spring apple leaves were the most fecund, whereas the females on apples did not oviposit. honeysuckle and spring leaves were the most suitable foods. apples, on the other hand, were the least suitable diet, which leads one to think that larvae could hardly complete their whole cycle on this fruit.
Effects of larval diet on the development and reproduction of Argyrotaenia sphaleropa (Meyrick) (Lepidoptera: Tortricidae)
Bentancourt, Carlos M.;Scatoni, Iris B.;Gonzalez, Alvaro;Franco, Jorge;
Neotropical Entomology , 2003, DOI: 10.1590/S1519-566X2003000400004
Abstract: the effect of six natural diets on the development and reproduction of argyrotaenia sphaleropa (meyrick) was measured under laboratory conditions, at 23 ±1oc temperature, 70 ± 10% rh, and photoperiod of 16l:8d. larvae were reared on three types of diet (spring leaves, summer leaves and fruits) from two different host plants (apple tree and grapevine). larval development, number of instars, survival, weight of pupae, fecundity, and fertility varied as a function of diets. the shortest time span of larval development, the greatest pupal weight, and the greatest adult fecundity and fertility was observed on insects feeding on spring apple leaves. the duration of larval development was longer on fruits than on leaves. the lowest larval survival occurred on apple fruits. larvae with a higher number of instars generally had an increase in the time span of larval development. larval development time span (4 out of 6 treatments) as well as pupal development time span (5 out of 6 treatments) was sex dependant. on all diets the females deposited the highest number of eggs on the first day of oviposition. the results obtained reinforce the hypothesis that the larvae of a. sphaleropa first feed on both apple and grapevine leaves, and then move to the fruits, where they cause serious damage.
Cathepsin B in Antigen-Presenting Cells Controls Mediators of the Th1 Immune Response during Leishmania major Infection
Iris J. Gonzalez-Leal,Bianca R?ger,Angela Schwarz,Tanja Schirmeister,Thomas Reinheckel,Manfred B. Lutz,Heidrun Moll
PLOS Neglected Tropical Diseases , 2014, DOI: 10.1371/journal.pntd.0003194
Abstract: Resistance and susceptibility to Leishmania major infection in the murine model is determined by the capacity of the host to mount either a protective Th1 response or a Th2 response associated with disease progression. Previous reports involving the use of cysteine cathepsin inhibitors indicated that cathepsins B (Ctsb) and L (Ctsl) play important roles in Th1/Th2 polarization during L. major infection in both susceptible and resistant mouse strains. Although it was hypothesized that these effects are a consequence of differential patterns of antigen processing, the mechanisms underlying these differences were not further investigated. Given the pivotal roles that dendritic cells and macrophages play during Leishmania infection, we generated bone-marrow derived dendritic cells (BMDC) and macrophages (BMM) from Ctsb?/? and Ctsl?/? mice, and studied the effects of Ctsb and Ctsl deficiency on the survival of L. major in infected cells. Furthermore, the signals used by dendritic cells to instruct Th cell polarization were addressed: the expression of MHC class II and co-stimulatory molecules, and cytokine production. We found that Ctsb?/? BMDC express higher levels of MHC class II molecules than wild-type (WT) and Ctsl?/? BMDC, while there were no significant differences in the expression of co-stimulatory molecules between cathepsin-deficient and WT cells. Moreover, both BMDC and BMM from Ctsb?/? mice significantly up-regulated the levels of interleukin 12 (IL-12) expression, a key Th1-inducing cytokine. These findings indicate that Ctsb?/? BMDC display more pro-Th1 properties than their WT and Ctsl?/? counterparts, and therefore suggest that Ctsb down-regulates the Th1 response to L. major. Moreover, they propose a novel role for Ctsb as a regulator of cytokine expression.
Regulation of DMD pathology by an ankyrin-encoded miRNA
Matthew S Alexander, Juan Casar, Norio Motohashi, Jennifer A Myers, Iris Eisenberg, Robert T Gonzalez, Elicia A Estrella, Peter B Kang, Genri Kawahara, Louis M Kunkel
Skeletal Muscle , 2011, DOI: 10.1186/2044-5040-1-27
Abstract: Inhibition of miR-486 in normal muscle myoblasts results in inhibited migration and failure to repair a wound in primary myoblast cell cultures. Conversely, overexpression of miR-486 in primary myoblast cell cultures results in increased proliferation with no changes in cellular apoptosis. Using bioinformatics and miRNA reporter assays, we have identified platelet-derived growth factor receptor β, along with several other downstream targets of the phosphatase and tensin homolog deleted on chromosome 10/AKT (PTEN/AKT) pathway, as being modulated by miR-486. The generation of muscle-specific transgenic mice that overexpress miR-486 revealed that miR-486 alters the cell cycle kinetics of regenerated myofibers in vivo, as these mice had impaired muscle regeneration.These studies demonstrate a link for miR-486 as a regulator of the PTEN/AKT pathway in dystrophin-deficient muscle and an important factor in the regulation of DMD muscle pathology.Duchenne muscular dystrophy (DMD) is a progressive, X-linked, muscle-wasting disease that occurs in 1 in 3,500 live male births [1]. Males with inactivating mutations in the DMD (dystrophin) gene make a nonfunctional protein which results in degenerating skeletal muscles, severely elevated creatine kinase (CK) levels, cardiac arrhythmias and secondary infections and subsequent respiratory failure due to the degeneration of the diaphragm muscles [2,3]. By contrast, patients with Becker muscular dystrophy (BMD) also have mutations in the DMD gene, but produce a partially functional dystrophin protein [3]. Patients with BMD have mildly progressive muscle weakness and elevated CK serum levels as well as variable longevity and mobility [3]. While the genetic mutations that cause DMD are now well established, the subsequent steps that lead to the disease pathogenesis are still emerging [4]. In dystrophin-deficient muscles, it has been demonstrated that the platelet-derived growth factor (PDGF) receptor (PDGFR) signaling pathway is signif
Infrastructure Enhancement to Support Value-Added Bioproduct Recovery  [PDF]
Jason S. Gordon, John B. Auel, Nia Blair-Agyeman, Iris B. Montague, Rubin Shmulsky
Natural Resources (NR) , 2018, DOI: 10.4236/nr.2018.94009
The purpose of this research was to identify and make available new and existing information to facilitate more effective response by individuals, organizations, and government entities when storms and other forms of catastrophic disturbance lead to unplanned influxes of downed timber and woody debris across the southeastern United States. To this end, this project explored attitudes and behaviors of stakeholders regarding their post disaster timber salvage experiences. Findings are reported from twelve focus group sessions with forestry decision makers, including landowners, loggers, foresters, and agency representatives. Data were analyzed using an iterative coding process that organized large quantities of text into fewer categories and identified emergent themes. Relationships between themes and categories were described within and across cases based on their concurrence, antecedents, or consequences. This technique was followed by a content analysis focusing on discovering underlying meanings and understanding explicit versus euphemistic terms. Findings center around economic limitations and opportunities, social networks in resource utilization, and diverse interpretations of the disaster event. As well, findings demonstrate how risk perceptions and disaster experience interact to construct social meanings for disaster and associated preparedness activities. Implications include value-added utilization options for woody storm debris that have been pursued in past storm events and lessons learned that can inform future decisions.
Use of Pristis spp. (Elasmobranchii: Pristidae) by Hunter-Gatherers on the Coast of S?o Paulo, Brazil
Gonzalez, Manoel M. B.;
Neotropical Ichthyology , 2005, DOI: 10.1590/S1679-62252005000300010
Abstract: artifacts made from rays (rostral teeth and spine) are very common in shell mounds on the coast of s?o paulo, brazil. the presence of the genus pristis among the studied species of elasmobranch fishes in this shell mounds reinforces the hypothesis these animals occurred in southeastern brazil, and were used by hunter-gatherers. i analyzed twelve rostral teeth of the genus pristis from shell mounds. the teeth have artificial marks left from making arrows and harpoons. the basic function of the teeth found in these shell mounds was the production of tools and ornaments. from the analyzed teeth, ten (83%) were associated to the faunal remain and two (17%) were associated with burials, and they can be considered as ceremonial or votive elements. there had been no new records of occurrence of the genus pristis on the coast of s?o paulo state in brazil, and there are a few studies on the use of their products in many ancient and contemporary human communities. this paper provide data about the distribution of rays of this genus in archaeological sites and the use of this resource by hunter-gatherers on the coast of s?o paulo.
Nascimento da Raia-viola, Zapteryx brevirostris (Müller & Henle) (Chondrichthyes, Rhinobatidae), em cativeiro
Gonzalez, Manoel M. B.;
Revista Brasileira de Zoologia , 2004, DOI: 10.1590/S0101-81752004000400010
Abstract: a female of zapteryx brevirostris were caught at queimada grande island, itanhaém, s?o paulo on 19/ii/2002, and transported to núcleo de pesquisa e estudo em chondrichthyes (nupec) captivities. at 21/ii/2002, the female gave birth to six pups (three males and three females). this is a first birth record of z. brevirostris in captivity.
Conical Distributions on the Space of Flat Horocycles
Fulton B. Gonzalez
Mathematics , 2009,
Abstract: Let $G_0=K\ltimes\mathfrak p$ be the Cartan motion group associated with a noncompact semisimple Riemannian symmetric pair $(G, K)$. Let $\frak a$ be a maximal abelian subspace of $\mathfrak p$ and let $\p=\a+\q$ be the corresponding orthogonal decomposition. A flat horocycle in $\p$ is a $G_0$-translate of $\q$. A conical distribution on the space $\Xi_0$ of flat horocycles is an eigendistribution of the algebra $\mathbb D(\Xi_0)$ of $G_0$-invariant differential operators on $\Xi_0$ which is invariant under the left action of the isotropy subgroup of $G_0$ fixing $\q$. We prove that the space of conical distributions belonging to each generic eigenspace of $\mathbb D(\Xi_0)$ is one-dimensional, and we classify the set of all conical distributions on $\Xi_0$ when $G/K$ has rank one.
Solutions of the Nonlinear Schrodinger Equation with Prescribed Asymptotics at Infinity
John B. Gonzalez
Mathematics , 2009,
Abstract: We prove local existence and uniqueness of solutions for the one-dimensional nonlinear Schr\"odinger (NLS) equations $iu_t + u_{xx} \pm |u|^2 u = 0$ in classes of smooth functions that admit an asymptotic expansion at infinity in decreasing powers of $x$. We show that an asymptotic solution differs from a genuine solution by a Schwartz class function which solves a generalized version of the NLS equation. The latter equation is solved by discretization methods. The proofs closely follow previous work done by the author and others on the Korteweg-De Vries (KdV) equation and the modified KdV equations.
Unbounded Solutions of the Modified Korteweg-De Vries Equation
John B. Gonzalez
Mathematics , 2009,
Abstract: We prove local existence and uniqueness of solutions of the focusing modified Korteweg - de Vries equation $u_t + u^2u_x + u_{xxx} = 0$ in classes of unbounded functions that admit an asymptotic expansion at infinity in decreasing powers of $x$. We show that an asymptotic solution differs from a genuine solution by a smooth function that is of Schwartz class with respect to $x$ and that solves a generalized version of the focusing mKdV equation. The latter equation is solved by discretization methods.
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