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Search Results: 1 - 10 of 224654 matches for " Ilka de Fatima Santana Ferreira;Silva Jr "
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A new method for the experimental induction of secundary biliary cirrhosis in wistar rats
Jorge Gracinda De Lourdes,Leonardi Luiz Sergio,Boin Ilka de Fatima Santana Ferreira,Silva Jr Orlando de Castro e
Acta Cirurgica Brasileira , 2001,
Abstract: The aim of this study was to describe a method for the induction of experimental secondary biliary fibrosis (SBF). Forty-seven Wistar rats were submitted to hepatic duct obstruction (OB group) for thirty days without ligature, section or cannulization causing interruption of biliary flow. This technique was carried out by simple traction of the bile duct passing it through the xiphoid appendix. Nine rats were submitted to a sham operation for bile duct stricture and seven rats comprised the control group. Blood samples were collected for the measurement of total bilirubin (TB), alkaline phosphatase (AP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Liver fragments were removed for morphological study. Thirty days after surgery TB, AP, ALT and AST levels were significantly increased in the hepatic duct ligation group compared to the sham operated group and the presence of SBF in the OB group was confirmed by morphological study of the liver. There was technical failure in 31.92% cases. The survival was 100% at fifteen days and 82.97% at the end of the experiment. We concluded that this simple surgical technique may be used to study the consequence of bile duct obstruction which could be a reversible process depending on the obstruction time. This technique can be carried out from cholestasis to fibrosis.
A new method for the experimental induction of secundary biliary cirrhosis in wistar rats
Jorge, Gracinda De Lourdes;Leonardi, Luiz Sergio;Boin, Ilka de Fatima Santana Ferreira;Silva Jr, Orlando de Castro e;Escanhoela, Cecilia Amelia Fazzio;
Acta Cirurgica Brasileira , 2001, DOI: 10.1590/S0102-86502001000200003
Abstract: the aim of this study was to describe a method for the induction of experimental secondary biliary fibrosis (sbf). forty-seven wistar rats were submitted to hepatic duct obstruction (ob group) for thirty days without ligature, section or cannulization causing interruption of biliary flow. this technique was carried out by simple traction of the bile duct passing it through the xiphoid appendix. nine rats were submitted to a sham operation for bile duct stricture and seven rats comprised the control group. blood samples were collected for the measurement of total bilirubin (tb), alkaline phosphatase (ap), alanine aminotransferase (alt) and aspartate aminotransferase (ast). liver fragments were removed for morphological study. thirty days after surgery tb, ap, alt and ast levels were significantly increased in the hepatic duct ligation group compared to the sham operated group and the presence of sbf in the ob group was confirmed by morphological study of the liver. there was technical failure in 31.92% cases. the survival was 100% at fifteen days and 82.97% at the end of the experiment. we concluded that this simple surgical technique may be used to study the consequence of bile duct obstruction which could be a reversible process depending on the obstruction time. this technique can be carried out from cholestasis to fibrosis.
Chemical pleurodesis for hepatic hydrothorax
BOIN, Ilka de Fatima Santana Ferreira;SILVA, Aurea Maria Oliveira;LEONARDI, Luiz Sergio;
Arquivos de Gastroenterologia , 2001, DOI: 10.1590/S0004-28032001000200008
Abstract: background - ascites can occur after hepatic diseases causing dyspnea, coughing and pain. when associated with pleural effusion it can also increase respiratory distress. in a bibliographic survey hydrothorax has been observed in up to 20% of the patients and the kind of treatment is still being discussed. objective ? this case report shows the occurrence of a large volume of ascites and pleural effusion in a cirrhotic patient and his treatment. methods ? report the case of a patient with hepatic cirrhosis due to chronic alcoholism and massive pleural effusion and ascites. he was submitted to several pleural paracenteses without success. scintigraphy showed the presence of ascites and confirmed a possible pleuroperitoneal communication. the thoracic surgery group was called and after evaluation it was decided to submit the patient to a pulmonary decortication and chemical pleurodesis. results ? these procedures were carried out with success. the pleural effusion was solved and the treatment of ascites was decided upon because the patient did not accept any surgical procedure. conclusion - this treatment could be applied to patients with hydrothorax who could not be submitted to a liver transplantation.
Chemical pleurodesis for hepatic hydrothorax
BOIN Ilka de Fatima Santana Ferreira,SILVA Aurea Maria Oliveira,LEONARDI Luiz Sergio
Arquivos de Gastroenterologia , 2001,
Abstract: Background - Ascites can occur after hepatic diseases causing dyspnea, coughing and pain. When associated with pleural effusion it can also increase respiratory distress. In a bibliographic survey hydrothorax has been observed in up to 20% of the patients and the kind of treatment is still being discussed. Objective - This case report shows the occurrence of a large volume of ascites and pleural effusion in a cirrhotic patient and his treatment. Methods - Report the case of a patient with hepatic cirrhosis due to chronic alcoholism and massive pleural effusion and ascites. He was submitted to several pleural paracenteses without success. Scintigraphy showed the presence of ascites and confirmed a possible pleuroperitoneal communication. The thoracic surgery group was called and after evaluation it was decided to submit the patient to a pulmonary decortication and chemical pleurodesis. Results - These procedures were carried out with success. The pleural effusion was solved and the treatment of ascites was decided upon because the patient did not accept any surgical procedure. Conclusion - This treatment could be applied to patients with hydrothorax who could not be submitted to a liver transplantation.
Prognostic Factors, Incidence and Management for Acute Variceal Bleeding in the Liver Transplantation Era  [PDF]
élio Rodrigues da Silva, Ilka de Fátima Santana Ferreira Boin, Eurípedes Soares Filho, Patrícia Alexsandra Nunes Barros Rodrgiues, Benedito Borges da Silva
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.24044
Abstract: Background: Gastroesophageal varices are the most common and clinically important part of the portosys-temic collaterals due to their tendency to rupture and cause massive gastrointestinal bleeding. Objective The aim of this work was to evaluate retrospectively the incidence and the factors of prediction for the treatment of bleeding by gastroesophageal varices in the patients attended in the Emergency Room of the Hospital State University of Campinas (Brazil) from the last ten years. Methods: The method used here consisted of a descriptive and retrospective study carried out from the analyses of the medical records of 769 patients with upper gastrointestinal bleeding of which 220 were admitted because of upper gastrointestinal bleeding caused by gastroesophageal varices during this same period. Results: The results showed that the gastroe-sophageal varices appeared in 28.6% of the patients and they were the second most common cause of upper gastrointestinal bleeding. While evaluating factors such as age, sex and the common individual records, it was proved that this disease occurs mainly among people between the third and the fifth decade of life, with the great majority of cases occurring in the fourth decade (29.2%), of which 76.8% were male. There was an association of hematemesis and melena in the admission of 57.7% of the patients and even ascites was a common diagnosis in 48.2% of them. Most of these patients (40%) were classified as Child class B at admis-sion. The early endoscopic exam was used for 96.8% of them and showed the presence of F3 varices in 38.5%, CB varices in 25.1% and RCS varices in 12.6%. Most of these varices (41.5%) were situated in the distal third of the esophagus. The most used pharmacological treatment was based on octreotide in 45.9% of the patients. They received 0.05 mg of intravenous octreotide and a maintenance dose of 1 mg per day in 98.6% of the cases, with efficacy in 74.2% of the patients. The tamponade with Sengstaken-Blakemore tube was applied in 30.5% of the patients, but it was observed that 69.7% of them did not present any consider-able progress and this situation led to their death. The endoscopic treatment was performed in 41.8% of the patients with efficacy in 81.5% of them. The sclerotherapy was used for 60.9% of the studied cases with Ethamolin® being the most used for sclerosing. Emergency surgery was used in just 8.6% of the patients studied and it controlled the bleeding in 78.9% of the cases. Conclusion: We concluded that gastroesophag-eal bleeding was an important cause of upper
Correla??o do nível de alfa-feto proteína, índice de sobrevida e recidiva tumoral em pacientes submetidosa transplante hepático
Ataide, Elaine Cristina;Machado, Ricardo Rossetto;Ribeiro, Maxwel Boga Capsy;Mattosinho, Thiago Jose Almeida Prado;Romani, Fernando Araujo;Escanhonela, Cecilia Amelia Fazzio;Boin, Ilka de Fatima Santana Ferreira;
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2011, DOI: 10.1590/S0102-67202011000100009
Abstract: background: liver transplantation for hepatocellular carcinoma (hcc) can result in a potential cure and greater survival than other less radical techniques. aim: to analyze the survival and recurrence rate in liver transplant recipients with hepatocellular carcinoma and alpha-fetoprotein over 200 ng/ml. method: analysis, in this retrospective study, 90 cirrhotic patients with hepatocellular carcinoma who underwent orthotopic liver transplantation between 1997 and 2009. liver lesions were diagnosed by preoperative doppler ultrasonography, abdominal computerized tomography and alpha-fetoprotein blood level. two groups were studied according to alpha-fetoprotein level over or below 200 ng/ml. the kaplan-meier method was used to study survival rate. the cox regression analysis was performed to study predictive factor to survival. results: it was observed that risk of death was 1% for each 10 units of alpha-fetoprotein over 200 ng/ml and 1% for each mm over 28 mm (tumor size). in this sample average age, gender, presence of recidivism, vascular invasion, incidental tumor, edmondson-steiner grade and milan criteria were similar when the two groups were submitted to multivarite analysis and the survival rate and the size of great nodule had a significant difference between the two groups. the survival rate was better for those patients with alpha-fetoprotein<200 ng/ml. conclusion: patients who had alpha-fetoprotein >200 showed worst survival and size of tumor was a predictive risk factor for mortality but this did not have influence in relationship to tumor recurrence
Pyruvate kinase activation and lipoperoxidation after selective hepatic ischemia in Wistar rats
Boin, Ilka de Fátima Santana Ferreira;Castro e Silva, Orlando de;Souza, Maria Eliza Jordani de;Santos, Antonio Cardoso;Leonardi, Luiz Sergio;
Acta Cirurgica Brasileira , 2006, DOI: 10.1590/S0102-86502006000700005
Abstract: purpose: hepatic ischemia and reperfusion can cause several problems in hepatic surgery. the aim of this study was to determine pyruvate kinase activation and lipid peroxidation after hepatic ischemia. methods: twenty-four wistar rats were submitted to 90 minutes of selective liver ischemia and 15 minutes of reperfusion. twelve animals were submitted to selective liver ischemia and reperfusion (group a) and the other 12 were submitted to sham operation (group b). after 15 minutes of reperfusion, the following parameters were measured: mean arterial pressure (map), alanine aminotransferase (alt), glycemia (gly), hepatic glycogen (gh), pyruvate kinase (pk) activation, hepatic glutathione (gsh) and malondialdehyde (mda). analysis of the results were made by the student t-test and has been considered significant difference for p<0.05. results: a and b were differents for all parameters analized. conclusion: the animals of group a showed reperfusion syndrome with a fall in map, activation of glycid metabolism through the glycolitic pathway and presence of lipid peroxidation compared to group b.
Rea??o anafilática durante transplante renal intervivos em crian?a alérgica ao látex: relato de caso
Potério, Glória Maria Braga;Braga, Angélica de Fátima de Assun??o;Santos, Regina Maria da Silva Feu;Gomes, Ilka de Fátima Santana Ferreira Boin;Luchetta, Maria Inez;
Revista Brasileira de Anestesiologia , 2009, DOI: 10.1590/S0034-70942009000200009
Abstract: background and objectives: latex allergy is becoming increasingly more frequent, affecting patients and health care professionals. the objective of this report was to present the case of a child with allergy to latex, who developed anaphylaxis during anesthesia for renal transplantation, and emphasize some of the multidisciplinary conducts used to decrease the risk of anaphylactic shock after graft reperfusion. case report: a male child, 5 years and 10 months old, p3 by the asa classification, with a history of allergy to latex diagnosed after contact with balloons and confirmed by rast test specific for latex and prick test, underwent renal transplantation of a live donor graft for end-stage renal disease secondary to urologic malformation. the protocols for patients with latex allergy adopted by the anesthesiology and nursing departments of the hospital das clínicas da unicamp were observed to avoid exposure of the child to latex. they started the day before the surgery by cleaning the operating rooms and substituting of all medical-hospital products by latex-free material. the equipment and materials used during the procedure were latex-free according to a technical report provided by the manufacturers. the surgery was done under general anesthesia and controlled mechanical ventilation. at the end of the surgery, the patient required blood transfusion, which was administered by a pressurizer; he developed cutaneous rash and the blood transfusion was discontinued, hydrocortisone was administered, and the infusion of crystalloids was increased. the child had an immediate and satisfactory response to the treatment. conclusions: latex allergy has become a public health problem and the knowledge of specific therapeutic conducts allows immediate treatment and decreases patient risks.
Avalia??o de métodos para recupera??o de pastagens de braquiária no agreste de Pernambuco: 1. aspectos quantitativos
Silva, Maria da Concei??o;Santos, Mércia Virgínia Ferreira dos;Dubeux Jr., José Carlos Batista;Lira, Mário de Andrade;Santana, Daniel Fernando Ydoyaga;Farias, Iderval;Santos, Venézio Felipe dos;
Revista Brasileira de Zootecnia , 2004, DOI: 10.1590/S1516-35982004000800011
Abstract: the experiment was performed to evaluate the productive response of a degraded b. humidicola pasture to different pasture recovery methods. it was used a split-plot within a confounded randomized block design. the main plot was represented by the combination among managements and fertilization levels and the sub-plot by the deferred periods. the experimental treatments were four recovery managements (no-tillage, harrowing, harrowing + corn as a companion crop, no-tillage + corn as a companion crop), two levels of nitrogen (0 and 100 kg/ha of n), two levels of phosphorus (0 and 100 kg/ha of p2o5) and, different periods of deferment (113, 156, 200 and 240 days), totalizing 64 treatments with three replications each one. it was found a significant interaction between recovery managements and p fertilization. the average dry matter accumulation (dma) was 7.52; 1.68; 1.10 and 4.43 t/ha of b. humidicola for no-tillage, harrowing, harrowing + corn as a companion crop, no-tillage + corn as a companion crop, respectively. the highest deferment period increased dma, plant heigth and b. humidicola participation in the botanical composition, as well reducing percentage of other species in the dma and percentage of uncovered soil. brachiaria humidicola pastures at the initial degradation stage, grown in low available phosphorus soils, may be recovered using a deferment period associated to a phosphorus fertilization.
Surgical Technique Used for Portal Vein Thrombosis when Thrombectomy Is Not Possible During Liver Transplantation  [PDF]
José Roberto Alves, Ilka de Fátima Santana Ferreira Boin, Anaísa Portes Ramos, Catherine Puliti Hermida Reigada, Nelson Caserta, Adilson Roberto Cardoso, Cristina Arrivabene Caruy, Elaine Cristina Ataíde, Jazon Romilson Souza Almeida
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.25055
Abstract: Portal vein thrombosis (PVT) was for a long time considered a barrier to liver transplantation. The aim of this study is to demonstrate the surgical technical options for portal vein reconstruction during liver transplantation in patients with PVT in which thrombectomy was not possible. Between September 1991 and March 2009, 420 liver transplanted patients were retrospectively analyzed, identifying 29 cases with PVT (6.9%). Preoperative diagnosis, preoperative risk factors, surgical technique options to treat various forms (grades) of PVT, postoperative recurrence and actuarial survival rates were studied. In three cases of PVT grade II and in one case PVT grade III the thrombectomy was insufficient, requiring some surgical technique options (13.79%). In two cases placement of iliac vein graft was performed, in one an anastomosis of the portal vein with collateral splenorenal vein and in the other with left gastric varicose. The actuarial survival rate for patients without PVT and patients with PVT and effective thrombectomy was 73.8% while those with PVT who needed some type of surgical option was 75%. Our results suggest that actuarial survival rates were similar among patients with PVT or PVT with effective thrombectomy when compared with PVT that required some surgical options.
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