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Search Results: 1 - 10 of 329673 matches for " Ibrahim S. Musa "
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Assessment of Genetic Relationship and Application of Computational Algorithm to Assess Functionality of Non-Synonymous Substitutions in DQA2 Gene of Cattle, Sheep and Goats  [PDF]
Steven B. Ugbo, Abdulmojeed Yakubu, Jude N. Omeje, Bwaseh S. Bibinu, Ibrahim S. Musa, Joseph O. Egahi, N. I. Dim
Open Journal of Genetics (OJGen) , 2015, DOI: 10.4236/ojgen.2015.54011
Abstract: The major histocompatibility complex (MHC) is a fundamental part of the immune system in nearly all vertebrates. DQA2 is a member of the MHC complex and an important candidate gene involved in susceptibility/resistance to various diseases. Therefore, the present study aimed at investigating computationally molecular genetic variation of DQA2 gene of cattle, sheep and goats especially on its evolution and differentiation within and among species as well as the attendant effects of the polymorphism on the function of DQA2 gene. A total of thirty three DQA2 nucleotide sequences comprising cattle (10), sheep (12) and goats (11) were retrieved from the GenBank. Forty seven amino acid substitutions of the wild type alleles located in the putative peptide coding region of caprine DQA2 alleles were obtained from the alignment of deduced amino acid sequences of goats. Out of these, eleven amino acid substitutions (H14L, H14R, L34M, E35L, G56S, G56R, 161V, A62E, D69Q, T72N and T72G) were returned neutral; an indication that they did not impair protein function. The Expected Accuracy (EA) ranged from 53% - 87%. For sheep, sixteen amino acid substitutions (A11P, A11T, A11G, A11M, L14S, L14T, V27L, V27S, G35S, S46T, D55E, L57T, L57A, L57G, K65Q and V68I) appeared beneficial while the rest forty seven appeared harmful (EA ranged from 53% - 93%). Twenty four amino acid substitutions did not impair the function of protein while seventy seven substitutions appeared to have a negative effect on the function of protein of cattle (EA ranged from 53% - 94%). The phylogeny based on nucleotide and amino acid sequences of DQA2 gene revealed the close relatedness of the caprine, ovine and bovine species. The present knowledge would be relevant for performing further genotype-phenotype research as well as pharmacogenetics studies in order to show association between caprine, ovine and bovine DQA2 allelic variation and the clinical progression of infectious diseases especially in a developing country such as Nigeria.
An Appraisal of Spatial Distribution of Solid Waste Disposal Sites in Kano Metropolis, Nigeria  [PDF]
Ali Ibrahim Naibbi, Umar Musa Umar
Journal of Geoscience and Environment Protection (GEP) , 2017, DOI: 10.4236/gep.2017.511003
Abstract: This paper describes a research project that has been conducted as part of the Kano Municipal waste management strategy. The aim is to quantify and to identify the existing locations of waste disposal sites by mapping their spatial distribution within the metropolitan Kano. QUICKBIRD satellite imageries; locations of existing waste disposal sites collected using Global Positioning System (GPS); and topographical map (1:5000 scale) of Kano metropolis were used to generate data for the study. The data were prepared and analysed using ArcMap 10.2.1 and Erdas Imagine 11 software to produce the spatial distribution maps for solid waste disposal sites within the metropolis. The result shows that out of the 300 existing waste disposal sites assessed, the city has fairly well-distributed waste disposal sites. Conversely, the disposal sites are more clustered in the centre of the metropolis than the outskirts. However, about 80 percent of the sites are either located very close to roads, settlements or water bodies. Also, while about 92 percent of the existing waste disposal locations are open space, only about 7 percent are containers (closed dumping sites). Correspondingly, about 89 percent are authorised dumping sites and only about 11 percent are unauthorised illegal. The study recommends that policymakers should intervene and relocate the existing unauthorized dump sites to more suitable areas.
Journal of Applied Phytotechnology in Environmental Sanitation , 2013,
Abstract: The development of Fadama project is to increase the incomes of users of rural land and water resources on a sustainable basis and help to reduce poverty and increase food security. The study estimated the profitability analysis of Fadama farming in Akure South Local Government Area of Ondo State, Nigeria. A purposive sampling method was used to select 70 respondents in the study area and structured questionnaire was administered to collect data from the respondents. Descriptive statistics such as frequency distribution and percentage were used to analyze the socio-economic characteristics of the fadama farmers. Gross margin analysis was also used to estimate costs and returns of fadama farming. Findings reveal that majority (81.4%), (57.1%) and (58.6%), were male, above 50 years of age with household size of 6 – 8 respectively. Most (52.9%) had no formal education with farm size (55.7%) of less than 0.6 hectare. The gross margin was computed to be 1,663,920, while total variable cost was 2,251,480 and total revenue was 3,915,400.The gross margin per farmer was 23,770.29. These show that fadama farming is profitable in the study area. The study recommends that government effort should be aimed at enhancing provision of credit for all interested fadama farmers at low interest rate to meet the cost of modern irrigation equipment and infrastructures.
Pathological Lesions in the Lungs of Neonatal Wistar Rats from Dams Administered Ethanol during Gestation
Sunday A. Musa,Shehu Ibrahim,Uduak. E. Umana,Samuel S. Adebisi
Asian Journal of Medical Sciences , 2012,
Abstract: This study was carried out to investigate the effects of ethanol ingestion during pregnancy on the fetal lungs development. Adult Wistar rats were used and grouped into four groups and each group having four females and two males. Group A was the control group received only distilled water, while groups B, C and D received 0.2 mL of 20, 25 and 30% ethanol orally respectively daily for seven days during the 4th to 10th day of gestation. After delivery, the fetal lungs were removed and fixed in 10% buffered formalin. The neonates’ lungs were prepared through histological techniques and stained with Haematoxylin and Eosin and were studied under the light microscope. The result showed alveolar degeneration, bronchiole-capillary thickening, bronchiolar degeneration and extravasations of erythrocyte in the ethanol treated groups while the control was normal. Ethanol ingestion during pregnancy could lead to ethanol-induced lung damage in the fetuses. Hence, alcohol ingestion should be avoided during pregnancy.
A Retrospective Analysis of Infectious Bursal Disease Diagnosed at Poultry Unit of Ahmadu Bello University, Nigeria
I.J. Mbuko,W.I. Musa,S. Ibrahim,L. Sa`idu
International Journal of Poultry Science , 2010,
Abstract: A five year retrospective study (2004-2008) of the prevalence of Gumboro disease (infectious bursal disease, IBD) and other poultry disease diagnosed at the poultry unit of the Ahmadu Bello University Veterinary Teaching Hospital (ABUVTH), Zaria, Kaduna Nigeria was conducted. A prevalence of 7.26% (107 cases) was recorded out of 1473 cases of poultry disease. Gumboro disease occurred throughout the year in Zaria with a high incidence during the festival periods (July-September, October-December and January-March). The outbreaks of IBD were observed to be 1.3 times more likely to occur in pre-rainy season (April-June). Improved breeds of chickens were 5.8 times more likely to suffer from IBD than free range local chickens with broilers being 5.7 times more likely to suffer from the disease than other type of birds followed by layers kept together with cockerels. The prevalence of IBD is influenced by age of birds with an increase in the likelihood of IBD occurring within the age range of 3-5 week. Birds at 5 weeks old were at highest risk. Chickens with one vaccination history against IBD were 8.2 times more likely to suffer from the disease compared to non-vaccinated chickens. This study recommends that poultry farmers should be encourage to improve on farm biosecurity and ensure that their birds are vaccinated at least twice, before 3 and 5 weeks of age (at 1 and 3 or 2 and 4 weeks of age).
Anthropometric evaluations and assessment of school furniture design in Nigeria: A case study of secondary schools in rural area of Odeda, Nigeria
Adekunle Ibrahim Musa
International Journal of Industrial Engineering Computations , 2011,
Abstract: This study was carried out on 621 schoolboys with age range of 12-17 years in Junior and Senior Secondary Schools in Odeda area of Odeda local government in Ogun State, Nigeria. Different anthropometric data were collected from these boys. It was observed from the results that all anthropometric dimensions of the school children increase with their age. Moreover, there exists a little difference between mean values of different anthropometric dimensions between the boys of 12-13 years (2.9% to 8.8%), 14-15 years (1.3% to 9.9%), and 16-17 years (1.4% to 5.5%). But the said differences become much higher (16.2% to 42.4%) when the same were compared between the children of 12 years and 17 years. Therefore, it can be said that the design of furniture for the children of 12 years will not match the children of 17 years. If single furniture is designed by considering dimensions of the children from 12 years to 17years, it will also not suit the children of all age groups. Therefore, in the present investigation, all the students have been divided into three combined age groups, e.g., 12-13 years, 14-15 years, and 16-17 years, and the percentile values (5th, 50th and 95th) of anthropometric measures, which will be helpful for designing of the classroom furniture.
Effect of Carbon Dioxide Emission to Vehicular Traffic and Environment in Ogun State, Nigeria
Adekunle Ibrahim MUSA
Lecture Notes in Engineering and Computer Science , 2012,
Mechanical-Assessment of Locally Fabricated Portable Generators for Production of Acetylene Gas in Abeokuta, Nigeria
Adekunle Ibrahim Musa
Lecture Notes in Engineering and Computer Science , 2012,
Immunological Characteristics of Hyperreactive Malarial Splenomegaly Syndrome in Sudanese Patients
Tayseer Alkadarou,Ahmed Musa,Abedelgader Alkadarou,Mohamed S. Mahfouz,Marita Troye-Blomberg,Ahmed M. Elhassan,Ibrahim M. Elhassan
Journal of Tropical Medicine , 2013, DOI: 10.1155/2013/961051
Abstract: Hyperreactive Malarial Splenomegaly (HMS) is defined as a massive enlargement of the spleen resulting from abnormal immune responses after repeated exposure to the malaria parasites. This study was carried out in Khartoum, Sudan. Sudan is considered to be one of the countries where HMS is quite prevalent. The objective of the study was to determine the incidence of HMS in patients who reported to the Omdurman Tropical Diseases Hospital (OMTDH) in Sudan and to investigate the basic laboratory and immunological characteristics of this condition in these patients. A cross-sectional study was carried out in OMTDH, and all patients with enlarged spleens were included in the study. Thirty-one out of 335 (9.3%) patients were diagnosed as having the HMS condition using international criteria for HMS diagnosis. The mean serum immunoglobulin M (IgM) levels in HMS patient groups were ?g/L, and this was significantly higher compared with geographically matched controls ( ). Immunoglobulin G (IgG) C anticircumsporozoite (CSP) antibody levels were higher in the HMS patients although the difference was not statistically significant, when compared with a group of patients with mild malaria. In comparison with na?ve European controls, both the HMS and the mild malaria groups had significantly higher antimalarial antibody levels and , respectively. Plasma levels of interleukin 10 (IL10) and interferon gamma (IFNγ) were significantly increased in the HMS patients compared with the healthy control donors ( and ) for IL10 and IFNγ, respectively. The findings of this study suggest that HMS is one of the significant causes of tropical splenomegaly in Sudan. HMS is associated with significant elevations of circulating IgM and antimalarial IgG antibodies as well as IL10 and IFNγ. 1. Introduction Hyperreactive Malarial Splenomegaly (HMS) is characterized by massive enlargement of the spleen in the tropics. The condition is prevalent in certain malarious regions of the Old World, mainly in Africa [1–5]. HMS seems to be associated with a high mortality; however, the natural history of HMS is not well documented. A 5-year-mortality rate of 50% has been reported in Uganda and New Guinea [6]. A mortality rate of 85% has been documented in hospitalized patients with gross splenomegaly. Whether HMS is responsible for this high mortality is a fact that still needs to be established [6]. Clinical Features. Symptoms of splenomegaly consist primarily of left upper quadrant pain with or without signs of hypersplenism dominating the clinical presentation of HMS. Early in the syndrome, the
Early Detection of Thyroid Gland Disorders for Students in the Faculty of Applied Medical Sciences  [PDF]
Saeed Bafaraj, Ibrahim Abbas, Saddig Jastaniah, Hanan Abbas, Alamin Musa
Open Journal of Medical Imaging (OJMI) , 2015, DOI: 10.4236/ojmi.2015.51005
Abstract: In this study 70 male students were participated to determine the thyroid disorder through ultrasonography. Thyroid scan was done in 70 students prospectively with no indicative of thyroid disease (age of 19 - 23 yrs). Thyroid scan for students who participated the study took place in the department of Faculty of Applied Medical Sciences, King Abdulaziz University by using an IU 22 Philips ultrasound machine with a 5 - 12 MHz linear transducer. Among the total number of the subjects, 26% was found with abnormal ultrasound findings, 17% of them with cystic nodule, while solid and mixed nodule represented 4% for each. The high rate of abnormal findings of thyroid gland in the study suggested that screening using ultrasound scan was useful in detecting early thyroid disorders.
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