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Search Results: 1 - 10 of 87710 matches for " I Nuamah "
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Hemispheric brain abscess: A review of 46 cases
T K Dakurah, M Iddrissu, G Wepede, I Nuamah
West African Journal of Medicine , 2006,
Chronic subdural haematoma: review of 96 cases attending the Korle Bu Teaching Hospital, Accra
TK Dakurah, M Iddrissu, G Wepeba, I Nuamah
West African Journal of Medicine , 2005,
Abstract: Background: Chronic subdural haematoma is not uncommon in Africa. Early diagnosis and treatment is satisfying. Simpler operative procedures are generally effective. This review is meant to find out the situation regarding the condition in Ghana. Study design: A retrospective study of patients with chronic subdural haematoma admitted to and treated by the Neurosurgical Unit of Korle Bu Teaching Hospital between January 1995 and December 1998 was undertaken. The case notes, computerise axial tomography (CT) scans and operative records were reviewed and the relevant data extracted. Incomplete records were excluded. Results: 96 patients were involved. The mean age of the patients was 46.9 years, with male to female ratio of 16: 1. The most common presenting feature was headache (64.7%). Time of injury to presentation was about 2 months. 81 were treated using burr hole and drainage and 15 by craniotomy and stripping of membranes. Eighty four were treated under general anaesthesia. Two were reoperated on because of recurrent bleed. There were two (2) deaths. Ninety patients had a Glasgow Outcome Score of good at the time of their last review. Conclusion: The data suggests that burr hole and closed drainage is a very effective method of managing CSDH.
Primary malignant head and neck tumours in Ghana: a survey of histopathological charts over two decades
Abdulai A.E,Nuamah I.K,Avogo D,Gyasi R.K
International Journal of Medicine and Biomedical Research , 2013,
Abstract: Background: Head and neck cancers are among the top ten malignancies worldwide. Their true extent is lacking in Ghana. There is no known published data covering the subject among Ghanaians. Aim: To determine the incidence of primary head and neck cancers seen at Korle Bu Teaching hospital, Ghana. Methods: A retrospective study of histopathological records of diagnosed head and neck cancers from 1989-2008. Results: 2,041 of 4,546 reports were malignant. 1342 were primary cancers. These were studied further in detail. The male: female ratio was 1.84:1. The oldest patient was 95 years and the youngest less than 1 year. The mean age was 45.08 years with a peak age-group of 51 to 60. The incidence of tumours in female exceeded that of male in only one age-group (81-90), with a ratio of 0.62:1. There were 59 different tumours. 45 of these occurred less than 5 times. Of those diagnosed, more than 5 times adenocystic carcinoma, osteosarcoma, chondrosarcoma and rhabdomyosarcoma occurred more frequently in females than males. 23 occurred only once. Squamous cell carcinoma (n=624) was the commonest pathology, followed by non-Hodgkin’s lymphoma (n=256), nasopharyngeal carcinoma (n=100), Hodgkin’s lymphoma (n=97) and adenocystic carcinoma (n=55). Conclusion: We observed a rising incidence of head and neck cancer. Squamous cell carcinoma is the commonest, occurring more commonly in men than women. The gender ratio is similar to that seen in most countries. This study offers a benchmark for future studies, planning resources and monitoring the efficiency of efforts to manage the different pathologies.
Oral pathologies seen in pregnant and non-pregnant women
BDRT Annan, K Nuamah
Ghana Medical Journal , 2005,
Abstract: The oral health status of a hundred pregnant women and that of one hundred non-pregnant women attending an antenatal clinic and gynaecological clinic respectively at Korle Bu Teaching Hospital was assessed for some common oral pathologies. The doctors and other health personnel managing the pregnant women were also quizzed to ascertain knowledge of any of these conditions. The aim was to find out if any oral condition was particularly prevalent in the pregnant women but not in the non-pregnant women. Our study confirms that in these women, pregnancy has an effect on the oral health status. However this effect is more likely due to the physiological changes associated with pregnancy than any other specific factors. Some oral conditions already present may be influenced by the hormonal changes, which in some cases exacerbate or ameliorate minor oral pathologies. Our findings were similar to that in other studies. However health workers who deal with the pregnant women in these clinics are less aware of these conditions and hence do not usually give any advice.
Parasitism of Plutella xylostella (L.) (Lepidoptera: Plutellidae) Populations on Cabbage Brassica oleracea var. capitata (L.) by Cotesia plutellae (Kurdjumov) (Hymenoptera: Braconidae) in Ghana
MA Cobblah, K Afreh-Nuamah, D Wilson, MY Osae
West African Journal of Applied Ecology , 2012,
Abstract: The study was carried out at the Weija Irrigation Company site at Weija, in the Greater Accra Region of Ghana, to determine the seasonal abundance of the major parasitoid of Plutella xylostella (L.) populations on cabbage, Brassica oleracea var. capitata (L.) during the rainy and the dry seasons. The results indicated that Cotesia plutellae (Kurdjumov) was the most abundant and important parasitoid of P. xylostella on cabbage. It accounted for about 92% of the parasitoids, and occurred in all the three seasons of planting. The rest consisted of four facultative hyperparasitoids: Oomyzus sokolowskii, Aphanogmus reticulatus, Elasmus sp. and a Trichomalopsis sp., and two primary parasitoids, Pediobius sp. and Hockeria sp. A significantly higher rate of parasitism (68.6 ± 12.9%, P < 0.05) of P. xylostella by C. plutellae occurred during the major rainy season and the least (9.9 ± 7.1) in the minor rainy season. Cotesia plutellae acted in a density dependent manner, and its numbers increased as that of the host in all three seasons. The coefficient of correlation was highest in the major rainy season (r = 0.97) with a coefficient of determination of 0.97. In the minor rainy season r = 0.55, and in the dry season r = 0.66. The annual coefficient of correlation was r = 0.51 and the coefficient of determination = 0.262. Hence, in an annual production of cabbage, 26.2% of the variation in parasitism was due to the variation in the number of P. xylostella. The results, therefore, indicate that C. plutellae can be used in the development of an integrated pest management programme (IPMP), against P. xylostella in Ghana.
Number needed to treat and number needed to harm with paliperidone palmitate relative to long-acting haloperidol, bromperidol, and fluphenazine decanoate for treatment of patients with schizophrenia
Srihari Gopal,Joris Berwaerts,Isaac Nuamah,et al
Neuropsychiatric Disease and Treatment , 2011,
Abstract: Srihari Gopal1, Joris Berwaerts1, Isaac Nuamah1, Kasem Akhras2, Danielle Coppola1, Ella Daly1, David Hough1, Joseph Palumbo11Johnson & Johnson Pharmaceutical Research & Development, LLC, Raritan, NJ, USA; 2Johnson & Johnson Pharmaceutical Services, LLC, Raritan, NJ, USABackground: We analyzed data retrieved through a PubMed search of randomized, placebo-controlled trials of first-generation antipsychotic long-acting injectables (haloperidol decanoate, bromperidol decanoate, and fluphenazine decanoate), and a company database of paliperidone palmitate, to compare the benefit-risk ratio in patients with schizophrenia.Methods: From the eight studies that met our selection criteria, two efficacy and six safety parameters were selected for calculation of number needed to treat (NNT), number needed to harm (NNH), and the likelihood of being helped or harmed (LHH) using comparisons of active drug relative to placebo. NNTs for prevention of relapse ranged from 2 to 5 for paliperidone palmitate, haloperidol decanoate, and fluphenazine decanoate, indicating a moderate to large effect size.Results: Among the selected maintenance studies, NNH varied considerably, but indicated a lower likelihood of encountering extrapyramidal side effects, such as akathisia, tremor, and tardive dyskinesia, with paliperidone palmitate versus placebo than with first-generation antipsychotic depot agents versus placebo. This was further supported by an overall higher NNH for paliperidone palmitate versus placebo with respect to anticholinergic use and Abnormal Involuntary Movement Scale positive score. LHH for preventing relapse versus use of anticholinergics was 15 for paliperidone palmitate and 3 for fluphenazine decanoate, favoring paliperidone palmitate.Conclusion: Overall, paliperidone palmitate had a similar NNT and a more favorable NNH compared with the first-generation long-acting injectables assessed.Keywords: long-acting injectables, first-generation antipsychotics, randomized, number needed to treat, number needed to harm, paliperidone palmitate, second-generation antipsychotics
Formulation of Weaning Food from Fermented Maize, Rice, Soybean and Fishmeal
E.A. Amankwah,J. Barimah,A.K.M. Nuamah,J.H. Oldham
Pakistan Journal of Nutrition , 2009,
Abstract: The use of fermented maize flour, soybean flour, rice flour and fish meal in weaning food formulation was investigated. Two blends, A and B, were formulated with and without fishmeal respectively. Blend A had soybean (20.09%), maize flour (43.96%), rice (31.81%) and fishmeal (4.14%) whilst Blend B had soybean (25.97%), maize flour (51.53%) and rice flour (22.5%). Chemical, sensory, microbial and shelf life evaluations were conducted. The protein and energy content in A and B were 19.13% and 404.34 kcal; 17.18% and 395.43 kcal respectively. The blends had low levels of minerals due to the removal of fish bones and grain pomace during formulation. The microbial count of the formulations - 1 x 10 cfu/ml of bacteria in A and B, 2 x 102 cfu/ml and 1.5 x 102 cfu/ml of mould in A and B respectively and 1.8 x 102 cfu/ml and 2.0 x 102 cfu/ml of yeast in A and B-were within the acceptable range of 1 x 105 cfu/ml, hence they are wholesome for consumption after 30 days. There was no significant difference (p>0.05) between the shelf life parameters of A and B after 30 days. The formulations were evaluated by 50 nursing mothers using a 5-point hedonic scale. Eighty-eight percent showed acceptance of the product requesting that it be processed on market scale. The facial expressions of babies fed with the product were also used for product assessment- 36% of the infants exhibited likeness, 10% dislike, 32% neither like nor dislike and 22% slightly disliked the products. There was no significant difference (p>0.05) between the acceptability of the products. The blends can therefore be used as alternatives to the weaning foods in the Ghanaian market as well as other countries in the world to improve the nutritional status of children and help to curb protein-energy malnutrition.
Comparative Susceptibility of Adult African Invader Fly Bactrocera invadens (Diptera: Tephritidae) to Some Selected Insecticides in Ghana
G. Abdullahi,H. Sule,D. Obeng-Ofori,K. Afre-Nuamah
Journal of Agricultural Science , 2012, DOI: 10.5539/jas.v4n8p182
Abstract: With the recent introduction of B. invadens in Africa and its devastating role in crop production, especially mango, with currently no registered insecticides for use against this fly in Ghana, the susceptibility of the fly to four commercially available insecticidal products namely, Cydim Super, Pyrinex 48 EC, Diazol 50 EW and Deltapaz was evaluated in the laboratory. The bioassay was conducted using three (3) different doses of each insecticidal product, by dipping 4x4 cm hardboard panels into the respective doses. Susceptibility of the flies to insecticides were assessed on freshly treated panels, 3-day-old and 6-day-old treated panels in some ventilated transparent bottles of 1 litre capacity. Adult flies aged between 4-12 days were used for the bioassays. The bioassay results indicated that the adult flies were more susceptible to Diazol (Diazinon) (LC50 = 0.6 ml/L; LC90 = 1.3 ml/L) and Pyrinex (Chlorpyrifos) (LC50 = 0.8 ml/L; LC90 =1.0 ml/L), and hence gave the least LT50 and LT90 times. Least susceptibility was recorded with Deltapaz (Deltamethrin) (LC50 = 3.1 ml/L; LC90 = 5.2 ml/L). It could be concluded that the control of B. invadens can be achieved more effectively by the use Pyrinex (Chlorpyrifos) and Diazol (Diazinon). The use of Pyrinex appears to be more economical to the resource poor farmers as it had least LC90 of 1.0 ml/L compared to 1.3 ml/L for Diazol in 30 min.
Adolescents’ Willingness and Intentions to Use Contraceptives in Rural Ghana  [PDF]
Sulemana Abubakari, Yeetey A. Enuameh, Emmanuel Mahama, Obed Ernest A. Nettey, George Adjei, Gifty Fosuaa Nuamah, Edward Apraku Anane, Robert Adda, Francis Dzabeng, Seeba Amenga-Etego, Charles Zandoh, Kwaku Poku Asante, Seth Owusu-Agyei
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.311029
Abstract: Efforts made to improve the availability and access to family planning services to adolescents in Ghana have not yielded the desired results. Adolescents in the Kintampo Health and Demographic Surveillance System area are no exception. This study explored contraceptive use intentions, preferences and their determinants among adolescents in rural Ghana. This was to contribute evidence towards achieving universal access to reproductive health. A cross-sectional study design was used to collect Sexual and Reproductive Health data in the Kintampo districts in 2011. A total of 1805 female adolescents were randomly sampled from a resident female adolescent population of 16,795. This study used intention and/or willingness of adolescents to use contraceptives as the outcome variable and the explanatory variables were demographic and socioeconomic factors. Descriptive and inferential statistical analyses were done. The findings indicated 54.3% of adolescents’ were willing to use contraceptives. Injectable was the most preferred contraceptive method among adolescents (48.6%); this was followed by the pill (29.6%) with the least being foam or jelly (0.2%). The most commonly cited reason for not intending to use contraception was adolescents’ opposition to family planning (31.5%) followed by a fear of side effects (25.8%). Age and education influenced adolescents’ willingness to use contraceptives in the future. Formal education of the young generation coupled with knowledge of contraceptive methods could yield positive outcomes for contraceptive use and ultimately reproductive health of the adolescent population in the near future.
A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia
Danielle Coppola, Yanning Liu, Srihari Gopal, Bart Remmerie, Mahesh N Samtani, David W Hough, Isaac Nuamah, Ahmad Sulaiman, Gahan Pandina
BMC Psychiatry , 2012, DOI: 10.1186/1471-244x-12-26
Abstract: In this 1-year prospective study, eligible patients (aged 18-65 years; Positive and Negative Syndrome Scale's total score ≤ 70) received an initial deltoid injection of PP 150 mg eq. The second injection one week later and subsequent once-monthly injections were deltoid or gluteal. All injections were to be PP 150 mg eq. Patients willing to participate in intensive pharmacokinetic sampling were classified as Treatment A. Patients unwilling to undergo intensive pharmacokinetic sampling or unable to tolerate the 150 mg eq. dose (consequently receiving flexible doses of 50, 100 or 150 mg eq.) were classified as Treatment B.Of the 212 patients (safety analysis set), 73% were men; 45% white; 20% black; 34% Asians; mean (SD) age 41 (10.2) years, and mean (SD) baseline Positive and Negative Syndrome Scale total score 54.9 (9.03). A total of 53% (n = 113) patients completed the study and 104 received PP 150 mg eq. throughout. Mean (SD) mode dose of PP was 144.8 (19.58) mg eq. The dosing initiation regimen resulted in rapidly achieved and maintained therapeutic paliperidone levels over the study (average concentrations during the dosing interval were 34.7, 40.0, and 47.8 ng/mL after the 2nd, 8th, and 14th injection respectively). Most frequent (≥ 10%) treatment-emergent adverse events were nasopharyngitis (n = 37), insomnia (n = 32), injection-site pain (n = 32), headache (n = 28), and tachycardia (n = 27). Akathisia (n = 19) and tremor (n = 11) were the most common extrapyramidal adverse events. 33 patients had an SAE and 27 discontinued due to treatment-emergent adverse events. No deaths were reported. Mean (SD) weight change from baseline was 2.5 (5.41) kg at endpoint. Patients' psychoses remained stable.Safety results after one-year therapy with the highest available dose of once-monthly paliperidone palmitate were consistent with results from previous studies, with no new concerns noted. Plasma concentrations were within the expected range.ClinicalTrials.gov: NCT0115044
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