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Search Results: 1 - 10 of 151114 matches for " Hui-Juan Zhang "
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Optical System Design of Binocular Head-mounted Projective Display with Wide-Field-of View
大视场双目头盔投影光学系统设计

ZHANG Hui-juan,
张慧娟

光子学报 , 2007,
Abstract: 设计了一种新型的头盔投影光学系统,解决了头盔系统中大视场和双目实现之间的设计矛盾,且有较小的重量和尺寸.系统的特性参量为:视场角60°,有效焦距30 mm,出瞳距离25 mm,出瞳直径12 mm.该系统由折/衍混合双高斯镜头、半透半反镜和回射屏组成.像差分析结果表明,系统的最大像散为0.27 mm,垂轴色差小于2.7μm,畸变小于3.8%,最小分辨角为0.5 mrad,成像质量高.
Gene expression profile analysis of tobacco leaf trichomes
Hong Cui, Song-Tao Zhang, Hui-Juan Yang, Hao Ji, Xiu-Jie Wang
BMC Plant Biology , 2011, DOI: 10.1186/1471-2229-11-76
Abstract: We have characterized Nicotiana tabacum leaf trichome gene expression using two approaches. In the first, a trichome cDNA library was randomly sequenced, and 2831 unique genes were obtained. The most highly abundant transcript was ribulose bisphosphate carboxylase (RuBisCO). Among the related sequences, most encoded enzymes involved in primary metabolism. Secondary metabolism related genes, such as isoprenoid and flavonoid biosynthesis-related, were also identified. In the second approach, a cDNA microarray prepared from these 2831 clones was used to compare gene expression levels in trichome and leaf. There were 438 differentially expressed genes between trichome and leaves-minus-trichomes. Of these, 207 highly expressed genes in tobacco trichomes were enriched in second metabolic processes, defense responses, and the metabolism regulation categories. The expression of selected unigenes was confirmed by semi-quantitative RT-PCR analysis, some of which were specifically expressed in trichomes.The expression feature of leaf trichomes in Nicotiana tabacum indicates their metabolic activity and potential importance in stress resistance. Sequences predominantly expressed in trichomes will facilitate gene-mining and metabolism control of plant trichome.Many terrestrial plants are covered with uni- or multi-cellular epidermal appendages called trichomes. Plant trichomes frequently function as the first line of defense against biotic and abiotic stresses by space hindrance [1]. Some plant species bear glandular trichomes that secrete a series of lipophilic substances and proteins, and are distinguished for their medicinal, culinary, fragrant and insecticidal properties. Functional genomic approaches are now emerging as powerful tools that can accelerate our understanding of trichomes. Significant progress has been made in cell differentiation and development research, particularly in Arabidopsis thaliana [2] and cotton [3]. However, limited information about metabolism and
Adaptation Habituation and the Inheritance of Acquired Charaeteiistics
适应、驯化与获得性遗传

Yao Dun-yi,Zhang Hui-juan,
姚敦义
,张慧娟

植物学报 , 1997,
Abstract:
Design and Realization of Region Network Manufacture ASP Platform
区域网络化制造ASP服务平台的设计与实现

YIN Jing,ZHANG Yu,ZHAO Hui-juan,
尹静
,张宇,赵慧娟

计算机应用研究 , 2005,
Abstract: This thesis designs an architecture of the region network manufacture ASP(Application Service Provider) platform by studying and analyzing the network manufacture of area and the mode of ASP. The thesis designs and develops the user management module by .
Transplantation of microencapsulated umbilical-cord-blood-derived hepatic-like cells for treatment of hepatic failure
Fang-Ting Zhang,Hui-Juan Wan,Ming-Hua Li,Jing Ye
World Journal of Gastroenterology , 2011,
Abstract: AIM: To investigate intraperitoneal transplantation of microencapsulated hepatic-like cells from human umbilical cord blood for treatment of hepatic failure in rats.METHODS: CD34+ cells in umbilical cord blood cells were isolated by magnetic cell sorting. In the in vitro experiment, sorted CD34+ cells were amplified and induced into hepatic-like cells by culturing with a combination of fibroblast growth factor 4 and hepatocyte growth factor. Cultures without growth factor addition served as controls. mRNA and protein levels for hepatic-like cells were analyzed by reverse transcription-polymerase chain reaction, immunohistochemistry and immunofluorescence. In the in vivo experiment, the hepatic-like cells were encapsulated and transplanted into the abdominal cavity of acute hepatic failure (AHF) rats at 48 h after D-galactosamine induction of acute hepatic failure. Transplantation with PBS and unencapsulated hepatic-like cells served as controls. The mortality rate, hepatic pathological changes and serum biochemical indexes were determined. The morphology and structure of microcapsules in the greater omentum were observed.RESULTS: Human albumin, alpha-fetoprotein and GATA-4 mRNA and albumin protein positive cells were found among cultured cells after 16 d. Albumin level in culture medium was significantly increased after culturing with growth factors in comparison with culturing without growth factor addition (P < 0.01). Compared with the unencapsulated group, the mortality rate of the encapsulated hepatic-like cell-transplanted group was significantly lower (P < 0.05). Serum biochemical parameters, alanine aminotransferase, aspartate aminotransferase and total bilirubin in the encapsulated group were significantly improvement compared with the PBS control group (P < 0.01). Pathological staining further supported these findings. At 1-2 wk post-transplantation, free microcapsules with a round clear structure and a smooth surface were observed in peritoneal lavage fluid, surviving cells inside microcapsules were found by trypan blue staining, but some fibrous tissue around microcapsules was also detected in the greater omentum of encapsulated group by hematoxylin and eosin staining.CONCLUSION: Transplantation of microencapsulated hepatic-like cells derived from umbilical cord blood cells could preliminarily alleviate the symptoms of AHF rats.
Effects of different nursing methods in treatment of phlebitis caused by cinobufacini injection
Hui-juan DONG
Zhong Xi Yi Jie He Xue Bao , 2007,
Abstract:
Aberrant DNA methylation in cervical carcinogenesis
Hui-Juan Yang
Chinese Journal of Cancer , 2013, DOI: 10.5732/cjc.012.10033
Abstract: Persistent infection with high-risk types of human papillomavirus(HPV) is known to cause cervical cancer; however, additional genetic and epigenetic alterations are required for progression from precancerous disease to invasive cancer. DNA methylation is an early and frequent molecular alteration in cervical carcinogenesis. In this review, we summarize DNA methylation within the HPV genome and human genome and identify its clinical implications. Methylation of the HPV long control region (LCR) and L1 gene is common during cervical carcinogenesis and increases with the severity of the cervical neoplasm. The L1 gene of HPV16 and HPV18 is consistently hypermethylated in invasive cervical cancers and can potentially be used as a clinical marker of cancer progression. Moreover, promoters of tumor suppressor genes (TSGs) involved in many cellular pathways are methylated in cervical precursors and invasive cancers. Some are associated with squamous cell carcinomas, and others are associated with adenocarcinomas. Identification of methylated TSGs in Pap smear could be an adjuvant test in cervical cancer screening for triage of women with high-risk HPV, atypical squamous cells of undetermined significance, or low grade squamous intraepithelial lesion (LSIL). However, consistent panels must be validated for this approach to be translated to the clinic. Furthermore, reversion of methylated TSGs using demethylating drugs may be an alternative anticancer treatment, but demethylating drugs without toxic carcinogenic and mutagenic properties must be identified and validated.
Effects of Microwavesynthesizing Parameters on Structure and Electrocatalytic Activity of Pt2Mo/C towards Methanol Oxidation
ZENG Xin,YUAN Xian-Xia,XIA Xiao-Yun,DU Juan,ZHANG Hui-Juan,MA Zi-Feng
无机材料学报 , 2010, DOI: 10.3724/sp.j.1077.2010.00359
Abstract: Pt2Mo/C was prepared by microwavesynthesis to improve the catalytic performance of Ptbased catalysts towards methanol xidation. Effects of reaction and sonicating time on the crystal structure, micromorphology and electrocatalytic activity of Pt2Mo/C were systematically investigated. The results show that the crystal structure of Pt2Mo/C is mainly determined by the reaction time while the sonicating time has little influence on it. The micromorphology of Pt2Mo/C is determined by oth the reaction and sonicating time. The influencing sequences of reaction and sonicating time on electrocatalytic activity of Pt2Mo/C are 10min>15min>20min >5min and 60min>100min>30min>0min, respectively. The optimized parameters of preparing Pt2Mo/C owing best catalytic activity towards methanol electrooxidation are 10min of reaction time and 60min of sonicating time.
Effects of cardiopulmonary bypass on tight junction protein expressions in intestinal mucosa of rats
Ying-Jie Sun, Wei-Min Chen, Tie-Zheng Zhang, Hui-Juan Cao, Jin Zhou
World Journal of Gastroenterology , 2008,
Abstract: AIM: To investigate the tight junction protein expressions of intestinal mucosa in an experimental model of cardiopulmonary bypass (CPB) in rats.METHODS: Thirty anesthetized rats were randomly divided into two groups: Group S (n = 10) served as sham operation and group C (n = 20) served as CPB which underwent CPB for 1 h. Expression of occludin and zonula occludens-1 (ZO-1) were determined by Western blotting and immunocytochemistry, respectively. Plasma levels of diamine oxidase (DAO) and d-lactate were determined using an enzymatic spectrophotometry.RESULTS: Immunohistochemical localization of occludin and ZO-1 showed disruption of the tight junctions in enterocytes lining villi at the end of CPB and 2 h after CPB. The intensities of the occludin and ZO-1 at the end of CPB were lower than those of control group (76.4% ± 22.5% vs 96.5% ± 28.5% and 62.4% ± 10.1% vs 85.5% ± 25.6%, P < 0.05) and were further lower at 2 h after CPB (50.5% ± 10.5% and 45.3% ± 9.5%, P < 0.05). Plasma d-lactate and DAO levels increased significantly (8.688 ± 0.704 vs 5.745 ± 0.364 and 0.898 ± 0.062 vs 0.562 ± 0.035, P < 0.05) at the end of CPB compared with control group and were significantly higher at 2 h after CPB than those at the end of CPB (9.377 ± 0.769 and 1.038 ± 0.252, P < 0.05). There were significant negative correlations between occludin or ZO-1 expression and DAO (r2 = 0.5629, r2 = 0.5424, P < 0.05) or d-lactate levels (r2 = 0.6512, r2 = 0.7073, P < 0.05) both at the end of CPB and 2 h after CPB.CONCLUSION: CPB markedly down-regulates the expression of occludin and ZO-1 proteins in intestinal mucosa of rats. The close correlation between expression of tight junctions (TJs) and plasma levels of DAO or d-lactate supports the hypothesis that intestinal permeability increases during and after CPB because of decreases in the expressions of TJs.
Insulin-Like Growth Factor-1 as a Prognostic Marker in Patients with Acute Ischemic Stroke
Jian-Hua Tang, Li-Li Ma, Tian-Xia Yu, Juan Zheng, Hui-Juan Zhang, Hui Liang, Peng Shao
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0099186
Abstract: Objective Insulin-like growth factor-1 (IGF-1) has been associated with cardiovascular risk factors and atherosclerosis. The aim of the present study was to evaluate the prognostic value of IGF-1 levels in patients with acute ischemic stroke (AIS). Methods All patients with first-ever AIS from August 1, 2012 to August 31, 2013 were recruited to participate in the study. Clinical data were collected. The National Institutes of Health Stroke Scale (NIHSS) score was assessed on admission blinded to serum IGF-1 levels. For the assessment of functional outcome at 90 days Modified Rankin Scale (mRS) was used. On admission, serum IGF-1 levels were determined by chemiluminescence immunoassay. The influence of IGF-1 levels on functional outcome and death was assessed by multivariate logistic regression analysis. Results Patients with an unfavorable outcomes and non-survivors had significantly decreased serum IGF-1 levels on admission (P<0.0001 for both). IGF-1 was an independent prognostic marker of functional outcome and death [odds ratio 0.89 (0.84–0.93) and 0.90 (0.84–0.95), respectively, P<0.0001 for both, adjusted for age, NIHSS score and other predictors] in patients with ischemic stroke. Serum IGF-1 levels ≤130 ng/mL was as an value indicator for unfavorable functional outcome (OR 3.31, 95% CI:1.87–5.62; P<0.0001), after adjusting for other significant confounders. Conclusions We reported a significant association between low serum IGF-1 levels and unfavorable functional outcome and death.
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