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Search Results: 1 - 10 of 18107 matches for " Hugo Kenzo;Martins "
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Schwannomas in the head and neck: retrospective analysis of 21 patients and review of the literature
Langner, Erwin;Del Negro, André;Akashi, Hugo Kenzo;Araújo, Priscila Pereira Costa;Tincani, Alfio José;Martins, Antonio Santos;
Sao Paulo Medical Journal , 2007, DOI: 10.1590/S1516-31802007000400005
Abstract: context and objective: schwannomas are benign neoplasms of the peripheral nerves originating in the schwann cells. according to their cellularity, they can be subdivided into antoni a or antoni b types. they are rare and usually solitary, with clearly delimited capsules. they occur in the head and neck region in only 25% of the cases, and may be associated with von recklinghausen's disease. the present study retrospectively analyzed some data on this disease in the head and neck region and reviewed the literature on the subject. design and setting: retrospective study at head and neck service, universidade estadual de campinas. methods: data on 21 patients between 1980 and 2003 were reviewed. the sites of cervical schwannomas and the intraoperative, histopathological and postoperative clinical status of these cases were studied. diagnostic methods, type of surgery and association with neurofibromatosis were evaluated. results: the patients' ages ranged from 16 to 72 years. four patients had a positive past history of type i neurofibromatosis or von recklinghausen's disease. the nerves affected included the brachial and cervical plexuses, vagus nerve, sympathetic chain and lingual or recurrent laryngeal nerve. the nerve of origin was not identified in six cases. tumor enucleation was performed in 16 patients; the other five required more extensive surgery. conclusion: schwannomas and neurofibromas both derive from schwann cells, but are different entities. they are solitary lesions, except in von recklinghausen's disease. they are generally benign, and rarely recur. the recommended surgical treatment is tumor enucleation.
Management of salivary gland adenoid cystic carcinoma: institutional experience of a case series
Tincani, Alfio José;Del Negro, André;Araújo, Priscila Pereira Costa;Akashi, Hugo Kenzo;Martins, Antonio Santos;Altemani, Albina Milani;Barreto, Gilson;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000100006
Abstract: context and objective: salivary gland tumor management requires long-term follow-up because of tumor indolence and possible late recurrence and distant metastasis. adenoid cystic carcinoma (acc) accounts for 10-15% of such tumors. the aim here was to evaluate surgical and clinical management, staging and follow-up of acc patients in one academic institution. design and setting: retrospective study at head and neck service, universidade estadual de campinas. methods: data on 21 patients treated between 1993 and 2003 were reviewed. management utilized clinical staging, histology and imaging. major salivary gland tumor extent was routinely assessed by preoperative ultrasonography. diagnosis, surgery type, margin type (negative/positive), postoperative radiotherapy and recurrence (presence/absence) were evaluated. results: there were eleven major salivary gland tumors (52.3%), seven submandibular and four parotid. ten patients (47.7%) had minor salivary gland acc (all in palate), while the submandibular was the most frequently affected major one. diagnoses were mostly via fine-needle aspiration (fna) and incision biopsy. frozen sections were used for six patients. there was good ultrasound/fna correlation. sixteen (76%) had postoperative radiotherapy. one (4.7%) died from acc and five now have recurrent disease: three (14.2%) locoregional and two (9.5%) distant metastases. conclusion: adenoid cystic carcinoma has locally aggressive behavior. in 21 cases, of acc, the facial nerve was preserved in all except in the few with gross tumor involvement. treatment was defined from physical examination, imaging, staging and histology.
Head and neck reconstruction using infrahyoid myocutaneous flaps
Tincani, Alfio José;Del Negro, André;Araújo, Priscila Pereira Costa;Akashi, Hugo Kenzo;Neves, Flávia da Silva Pinto;Martins, Ant?nio Santos;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000500007
Abstract: context and objective: the use of pedicled myocutaneous flaps in head and neck reconstruction is widely accepted. here we describe our experience with infrahyoid flaps (ihfs) employed to cover surgical defects in the oral cavity and oropharynx in patients with benign and malignant tumors. the aim was to evaluate the success rate for infrahyoid myocutaneous flap procedures performed at a single institution. design and setting: retrospective study, at the head and neck surgery service, unicamp. methods: fourteen ihfs were used to reconstruct surgical defects in eleven men (78.5%) and three women (21.5%) with a mean age of 66.4 years. the anterior floor of the mouth was reconstructed in nine patients (64.2%), the base of tongue in three (21.4%), the lateral floor in one (7.1%), and the retromolar area (7.1%) in one. thirteen patients (92.8%) had squamous cell carcinoma (scc) and one (7.2%) ameloblastoma. the disease stage was t3 in eight (61.5%) of the scc cases and t4 in five (38.5%). results: no patient presented total flap loss or fistula. the most common complication was epidermolysis, which delayed the beginning of oral ingestion. the patients with scc received postoperative radiotherapy without major consequences to the flap. conclusion: ihf is a safe and reliable procedure for reconstructing head and neck surgical defects. due to its thinness and malleability, its use for oral cavity and oropharynx defects provides favorable cosmetic and functional outcomes. complications, when present, are easy to manage.
Improved Integration Time Estimation of Endogenous Retroviruses with Phylogenetic Data
Hugo Martins,Palle Villesen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0014745
Abstract: Endogenous retroviruses (ERVs) are genetic fossils of ancient retroviral integrations that remain in the genome of many organisms. Most loci are rendered non-functional by mutations, but several intact retroviral genes are known in mammalian genomes. Some have been adopted by the host species, while the beneficial roles of others remain unclear. Besides the obvious possible immunogenic impact from transcribing intact viral genes, endogenous retroviruses have also become an interesting and useful tool to study phylogenetic relationships. The determination of the integration time of these viruses has been based upon the assumption that both 5′ and 3′ Long Terminal Repeats (LTRs) sequences are identical at the time of integration, but evolve separately afterwards. Similar approaches have been using either a constant evolutionary rate or a range of rates for these viral loci, and only single species data. Here we show the advantages of using different approaches.
A PALAVRA-GESTO NA NARRATIVA DE E A DE QUEIRóS
Vitor Hugo Fernandes Martins
Signótica , 1997, DOI: 10.5216/sig.v9i1.7400
Abstract: Neste ensaio sobre a narrativa de José Maria E a de Queirós (1845 - 1900), mais especificamente sobre três romances, a saber, O Mistério da Estrada de Sintra (1870), Os Maias (1888) e A Tragédia da Rua das Flores (1980), intentamos mostrar e demonstrar um procedimento estilístico, no qual o signo gestual vale tanto quanto o verbal. A partir de amostragens textuais dos supraditos romances, propomo-nos a decodificar a significa o do corpo e da voz na apresenta o e na composi o das personagens queirosianas.
Study on Sustainable Rainwater Resource Utilization—Towards Deepening of Homo Environmentics  [PDF]
Akira Hiratsuka, Kenzo Wakae
Journal of Water Resource and Protection (JWARP) , 2019, DOI: 10.4236/jwarp.2019.115029
Abstract: This paper mainly investigated the value of the rainwater by introducing a “Logic of Encounter” that is a new logic beyond the logos and lemma through the metaphors which compare the real rainwater to one’s life. A consideration regarding sustainable rainwater resource utilization has been described and the main results are summarized in the paper.
Evolution of radon dose evaluation
Fujimoto Kenzo
Nuclear Technology and Radiation Protection , 2004, DOI: 10.2298/ntrp0401003f
Abstract: The historical change of radon dose evaluation is reviewed based on the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) reports. Since 1955, radon has been recognized as one of the important sources of exposure of the general public. However, it was not really understood that radon is the largest dose contributor until 1977 when a new concept of effective dose equivalent was introduced by International Commission on Radiological Protection. In 1982, the dose concept was also adapted by UNSCEAR and evaluated per caput dose from natural radiation. Many researches have been carried out since then. However, lots of questions have remained open in radon problems, such as the radiation weighting factor of 20 for alpha rays and the large discrepancy of risk estimation among dosimetric and epidemiological approaches.
Generations of Quarks and Leptons from Noncompact Horizontal Symmetry
Kenzo Inoue
Physics , 1994, DOI: 10.1143/PTP.93.403
Abstract: The three chiral generations of quarks and leptons may be generated through a spontaneous breakdown of the noncompact horizontal gauge symmetry $G_{H}$ which governs, together with the standard gauge symmetry ${SU(3) \times SU(2) \times U(1)}$, the world in a vectorlike manner. In a framework of supersymmetric theory, the simplest choice ${G_{H}=SU(1,1)}$ works quite well for this scenario in which quarks, leptons and Higgses belong to infinite dimensional unitary representation of $SU(1,1)$. The relevance of the scenario to the hierarchical structure of their Yukawa coupling matrices are discussed.
The influence of the blood pressure on the venous cerebral flow measured by magnetic susceptibility (SWI) technique  [PDF]
Hugo Martins, Marlene Carreiras, M. Margarida Ribeiro, Paulo Sousa, Carina Silva-Forte
Journal of Biomedical Science and Engineering (JBiSE) , 2013, DOI: 10.4236/jbise.2013.63A053
Abstract:
Susceptibility Weighted Image (SWI) is a Magnetic Resonance Imaging (MRI) technique that combines high spatial resolution and sensitivity to magnetic susceptibility differences between tissues, it is extremely sensitive to venous blood due to its iron content of deoxyhemoglobin. The aim of this study was to evaluate the differences in the cerebral venous vasculature produced by the value’s variation of blood pressure. 20 subjects (10 hypertensive and 10 normotensive patients) underwent a MRI system with field strength of 1.5 T using a synergy head coil (7 channels). The obtained sequences were T1w, T2w-FLAIR, T2* and SWI. The value of Contrast-to-Noise Ratio (CNR) was assessed in MinIP (Minimum Intensity Projection) and Magnitude images, through drawing free hand ROIs in venous structures: Superior Sagittal Sinus (SSS) Internal Cerebral Vein (ICV) and Sinus Confluence (SC). The obtained values were presented in descriptive statistics-quartiles and extremes diagrams. The results were compared between groups. CNR shown higher values for normotensive group in MinIP (108.89 ± 6.907) to ICV; (238.73 ± 18.556) to SC and (239.384 ± 52.303) to SSS. These values are bigger than images from Hypertensive group about 46 au in average. Comparing the results of Magnitude and MinIP images, there were obtained lower CNR values for the hypertensive group. There were differences in the CNR values between both groups, being these values more expressive in the large vessels-SSS and SC. The SWI is a potential technique to evaluate and characterize the blood pressure variation in the studied vessels adding a physiological perspective to MRI and giving a new approach to the radiological vascular studies.
Seed Quality Evaluation by Tetrazolium Staining of Parkia multijuga Benth  [PDF]
Marcelle Auday Costa, Elizabeth Santos Cordeiro Shimizu, Noemi Vianna Martins Le?o, Hugo Alves Pinheiro
Agricultural Sciences (AS) , 2018, DOI: 10.4236/as.2018.95040
Abstract: The purpose of this study was to develop a staining pattern through tetrazolium test to evaluate seed viability of Parkia multijuga Benth (fava-arara-tucupi). The seeds were scarified, soaked into water and distilled for 48 hours for tegument removal and then immersed in a 0.05%; 0.1%; and 0.3% tetrazolium solution for 6; 18 and 24 hours at 35°C, in the dark. The evaluation was performed on the basis of stain intensity and aspect of the tissues. Based on color patterns, the seed images were classified in eight viability classes. Those results were compared with the germination test in a laboratory. The treatment in concentration of 0.1% for 6 hours was considered adequate for the specie, considering the adequate staining and time for analysis.
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