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Search Results: 1 - 10 of 3021 matches for " Hossein;Khatami "
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Comparison of efficacy of intralesional injection of meglumine anti-moniate once-weekly with twice-weekly in the treatment of anthroponotic cutaneous leishmaniasis in Mashhad: a randomized clinical trial
Ali Khamesipour,Mohammad Hossein Ghoorchi,Alireza Khatami,Seyed Ebrahim Eskandari
Dermatology and Cosmetic , 2011,
Abstract: Background and Aim: Cutaneous leishmaniasis (CL) is endemic in Iran, where it is one of the most important health problems. Both anthroponotic CL (ACL) caused by L. tropica and zoonotic CL (ZCL) caused by L. major are reported. Antimoniate derivatives as the standard therapy for CL need multiple injections and are not easy to tolerate for the patients. This study was conducted in Mashhad to compare the efficacy of weekly versus twice a week intralesional injections of meglumine antimoniate (MA) in the treatment of ACL."n"nMethods: This randomised controlled trial was performed during 2006 to 2008 in Mashhad, Iran. Using computerized sequence of random numbers, participants were randomly allocated in the two arms of the study: one receiving weekly and the other receiving twice-a-week intralesional injections of MA. The lesion size, induration and healing rate were assessed, recorded and compared. Healing was defined as complete re-epithelialisation and disappearance of induration."n"nResults: A total of 252 suspected CL patients with 372 lesions were screened. 82 parasitologically proven cases with 121 lesions caused by L. tropica were included and 74 patients with 113 lesions completed the study. At 12th week after initiation of treatment, complete healing was observed in 38 out of 44 lesions (86.4%) in the group which received weekly intralesional MA injection. The median time-to-heal in this group was 36 days (95% confidence interval [CI]: 32.0-39.9). Complete healing was recorded in 60 out of 69 lesions (86.9%) in the group which received twice a week intralesional injections of MA with a median time-to-heal of 25 days (95% CI: 20.9-29.1). While no significant difference was observed between the two groups in terms of complete healing rate (P=0.999), time-to-heal was significantly different between the 2 groups (P=0.003)."n"nConclusion: It seems that the effectiveness of twice-weekly intralesional injections of MA is similar to once-weekly regimen while the former regimen causes more rapid healing of lesions.
Biochemical association between essential trace elements and susceptibility to Leishmania major in BALB/c and C57BL/6 mice
Amini, Marzyeh;Nahrevanian, Hossein;Khatami, Shohreh;Farahmand, Mahin;Mirkhani, Fatemeh;Javadian, Seifoddin;
Brazilian Journal of Infectious Diseases , 2009, DOI: 10.1590/S1413-86702009000200002
Abstract: several enzymes that contribute to immune system responses require zinc and copper as trace elements for their activity. we examined zinc and copper levels in two susceptible balb/c mouse lines and resistant c57bl/6 mice infected with leishmania major mrho/ir/75/er, a prevalent strain that causes cutaneous leishmaniasis in iran. serum zn and cu were determined by flame atomic absorption spectrophotometry. higher cu levels were found in infected c57bl/6 mice and higher zn levels were found in infected balb/c mice. also, cu/zn ratios were increased in both the balb/c and the c57bl/6 mice. we conclude that concentrations of essential trace elements vary during cutaneous leishmaniasis infection and that this variation is associated with susceptibility/resistance to leishmania major in balb/c and c57bl/6 mice. we detected zn deficiency in the plasma of infected balb/c mice; possibly, therapeutic administration of zn would be useful for treating this form of leishmaniasis. increases in cu level might increase resistance to leishmaniasis. based on our findings, the cu/zn ratio could be a useful marker for the pathophysiology of leishmaniasis.
Iranian Journal of Child Neurology , 2012,
Evaluation of diagnostic test accuracy studies
Alireza Khatami
Dermatology and Cosmetic , 2011,
Abstract: "nIn the recent years, advances in different fields of technology have been resulted in a dramatic increase in the diagnostic methods and tests in different branches of clinical medicine with a consequent increase in the number of scientific publications related to the application of those tests and methods in the diagnosis or prevention of diseases. Dermatology is not an exception. Since, evidence-based medicine emphasizes on the appropriate use of the current best clinical research evidence in the diagnosis or treatment of each individual patient acknowledging his/her values, the capability of dermatologists in appraisal and application of the publications, which reports the results of diagnostic test accuracy studies cannot be ignored. In this article, after a brief review on basic issues in diagnostic test accuracy studies, principles of critical appraisal of these studies, from an evidence-based viewpoint, will be discussed. General strategies for evaluation of validity, applicability and quality assessment of a diagnostic test study will be provided.
A Note On Gorenstein Injective Dimension
Leila Khatami
Mathematics , 2006,
Abstract: The Chouinard's formula for injective dimension is extended to the Gorenstein injective dimension.
The smallest part of the generic partition of the nilpotent commutator of a nilpotent matrix
Leila Khatami
Mathematics , 2013,
Abstract: Let $k$ be an infinite field. Fix a Jordan nilpotent $n$ by $n$ matrix $B = J_P$ with entries in $k$ and associated Jordan type $P$. Let $Q(P)$ be the Jordan type of a generic nilpotent matrix commuting with $B$. In this paper, we use the combinatorics of a poset associated to the partition $P$, to give an explicit formula for the smallest part of $Q(P)$, which is independent of the characteristic of $k$. This, in particular, leads to a complete description of $Q(P)$ when it has at most three parts.
The poset of the nilpotent commutator of a nilpotent matrix
Leila Khatami
Mathematics , 2012,
Abstract: Let $B$ be an $n \times n$ nilpotent matrix with entries in an infinite field $\k$. Assume that $B$ is in Jordan canonical form with the associated Jordan block partition $P$. In this paper, we study a poset $\mathcal{D}_P$ associated to the nilpotent commutator of $B$ and a certain partition of $n$, denoted by $\lambda_U(P)$, defined in terms of the lengths of unions of special chains in $\mathcal{D}_P$. Polona Oblak associated to a given partition $P$ another partition $Ob(P)$ resulting from a recursive process. She conjectured that $Ob(P)$ is the same as the Jordan partition $Q(P)$ of a generic element of the nilpotent commutator of $B$. Roberta Basili, Anthony Iarrobino and the author later generalized the process introduced by Oblak. In this paper we show that all such processes result in the partition $\lambda_U(P)$.
Indonesia, ASEAN, and the Rise of China: Indonesia in the Midst of East Asia’s Dynamics in the Post-Global Crisis World
Hesam Khatami
International Journal of Nations Research , 2018, DOI: -
Abstract: The rise of China and the more dynamic ASEAN-China relations become salient challenges for Indonesia in the wake of the global financial crisis. Economically, cooperation between ASEAN and China through the ACFTA has caused significant negative impacts to Indonesia, as seen from the continuous trade deficit, industrial downturn, and rising unemployment. In the political and military field, there has been changes in China’s political gesture from accommodative to a more assertive one in the light of uncertainty in the South China Sea. The situation has raised the discourse to invite extra regional powers, especially the US, to be more actively involve in the regional security arrangement. In this context, Indonesia sees ASEAN as an important instrument to bridge all powers in the region by looking forward for dialogue and cooperation instead of conflict and military disputes.
Implications of Classification of Methodological Decisions in Flooding Analysis from Hurricane Katrina
Reza Khatami,Giorgos Mountrakis
Remote Sensing , 2012, DOI: 10.3390/rs4123877
Abstract: Recent climatic patterns indicate that extreme weather events will increase in frequency and magnitude. Remote sensing offers unique advantages for large-scale monitoring. In this research, Landsat 5 remotely sensed imagery was used to assess flooding caused by Hurricane Katrina, one of the worst natural disasters in the US over the past decades. The objective of our work is to assess whether decisions associated with the classification process, such as location of reference data and algorithm choice, affected flooding results and subsequent analysis using census data. Maximum Likelihood (ML) and Back Propagation Neural Network (NN) were the tested algorithms, the former reflecting a simple and popular classifier, and the latter an advanced but complex method. Flooding estimations were almost identical within the reference sample area, 124.4 km2 for the ML classifier and 123.7 km2 for the NN classifier. However, large discrepancies were found outside the reference sample area with the ML predicting 462.5 km2 and the NN identifying 797.2 km2 as flooded, almost twice the amount. Further investigation took place to evaluate the influence of the classification method to a social study, namely the racial characteristics of flooded areas. Using Census 2000 data, our study area was segmented in census tracts. Results indicated a strong positive correlation between concentration of African Americans and proportional residential flooding. Pairwise T-Tests also verified that flooding among different African American concentrations was statistically different. There were no significant differences between the ML and NN methods in the results interpretation, which is mostly attributed to the significant geographic overlap between reference sample area and the examined census tracts. This study suggests that emergency responders should exercise significant caution in their decision making when using classification products from undersampled geographic areas in terms of classification reference data.
"Incidence And Epidemiology Of Esophagitis In Children Admitted To Endoscopy Unit Medical Center Of Children In Tehran "
Rafeey M,Khatami GH
Tehran University Medical Journal , 2004,
Abstract: Background: There has been a little attention to pediatrics esophagus problems until recent years. The term esoghagitis can be used to described chemical, infectious, inflammatory, ischemic, immunologic and degenerative abnormalities. Prevalence of reflux esophagitis varies between 2 to 5 percent of general population but little data about its incidence in pediatric age groups. The aim of this study was to evaluate the epidemiology and prevalence of esophagitis and study of symptom, diagnostic measures, therapeutic intervention and prevention of its complication. Materials and Methods: In this prospective and cross sectional study 500 patient under16 years with upper digestive complaints or alteration of their state of health under went upper endoscopy, with special attention paid to esophagus. Results: Among 500 children (205 male, 207 female), pathology reported esophagi is in 325 cases. Majority of the patient were 8 to12 years. Most common complaints was abdominal pain (45/7%) and the second complaints was vomiting (13%), but most common complaints in severe esophagitis was melena (66%) and hematemes(18/8%). Most of patient (63% ) had a mild grade of esophagitis. When difference between endoscopy and pathology compared: Mild esophagitis in endoscopy (67%) ,but in pathology was (63%), moderate esophagitis (14/7%) in endoscopy was (17%) in pathology and severe form 2/8% in endoscopy but (4/9%)in pathology. Conclusion: According to results of our study in children age group with chronic abdominal pain ,vomiting ,excessive regurgitation, failure to thrive, we noticed that esophagitis is common etiologic factor. Histological esophagitis frequently occur in the absence of gross endoscopic findings and we need biopsy and histological examination to confirm diagnosis.
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