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Search Results: 1 - 10 of 8341 matches for " Horacio Nelson; "
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Plasma extravasation mediated by lipopolysaccharide-induction of kinin B1 receptors in rat tissues
Paulo Roberto Wille,Richard Vitor,Nelson Horacio Gabilan,Mauro Nicolau
Mediators of Inflammation , 2001, DOI: 10.1080/09629350124164
Abstract: The present study was performed to: (a) evaluate the effects of kinin B1 (Sar{D-Phe8}-des-Arg9-BK; 10 nmol/kg) and B2 (bradykinin (BK); 10 nmol/kg) receptor agonists on plasma extravasation in selected rat tissues; (b) determine the contribution of a lipopolysaccharide (LPS) (100 μ g/kg) to the effects triggered by B1 and B2 agonists; and (c) characterize the selectivity of B1 ({Leu8}desArg9-BK; 10 nmol/kg) and B2 (HOE 140; 10 nmol/kg) antagonists as inhibitors of this kinin-induced phenomenon. B1 and B2 agonists were shown to increase plasma extravasation in the duodenum, ileum and also in the urinary bladder of the rat. LPS pretreatment enhanced the plasma extravasation mediated only by the B1 agonist in the duodenum, ileum, trachea, main and segmentar bronchi. These effects were prevented by the B1. but not the B2 antagonist. In normal rats, the B2 antagonist inhibited the effect of B2 agonist in all the tissues analyzed. However, in LPS-treated rats, the B2 antagonist was ineffective in the urinary bladder.
An algorithm for determining the K-best solutions of the one-dimensional Knapsack problem
Yanasse, Horacio Hideki;Soma, Nei Yoshihiro;Maculan, Nelson;
Pesquisa Operacional , 2000, DOI: 10.1590/S0101-74382000000100011
Abstract: in this work we present an enumerative scheme for determining the k-best solutions (k > 1) of the one dimensional knapsack problem. if n is the total number of different items and b is the knapsack's capacity, the computational complexity of the proposed scheme is bounded by o(knb) with memory requirements bounded by o(nb). the algorithm was implemented in a workstation and computational tests for varying values of the parameters were performed.
An algorithm for determining the K-best solutions of the one-dimensional Knapsack problem
Yanasse Horacio Hideki,Soma Nei Yoshihiro,Maculan Nelson
Pesquisa Operacional , 2000,
Abstract: In this work we present an enumerative scheme for determining the K-best solutions (K > 1) of the one dimensional knapsack problem. If n is the total number of different items and b is the knapsack's capacity, the computational complexity of the proposed scheme is bounded by O(Knb) with memory requirements bounded by O(nb). The algorithm was implemented in a workstation and computational tests for varying values of the parameters were performed.
Hydrokinetic Assessment of the Kvichak River near Igiugig, Alaska, Using a Two-Dimensional Hydrodynamic Model  [PDF]
Horacio Toniolo
Energy and Power Engineering (EPE) , 2012, DOI: 10.4236/epe.2012.46056
Abstract: Two-dimensional hydrodynamic simulations were performed on a monthly basis along 2.5 km of the Kvichak River near Igiugig in southwest Alaska, USA, to estimate flow conditions and to assess the hydrokinetic potential of the river reach. Instantaneous power density function along the computational domain was calculated. Study results indicate that two areas may be suitable for deploying turbines. The best option is located near the town, where the channel is relatively straight. A second possible site is located near the end of the study reach (approximately 2.3 km, along the river, from Lake Illiamna). Monthly-averaged velocities along the thalweg ranged from 1.7 to 2.7 m/s; and from 1.1 to 2 m/s at the upstream and downstream sites, respectively. Similarly, averaged values for the instantaneous power density, reduced by an extraction coefficient, were approximately 1500 and 5500 W/m2 during April and September, respectively, at the upstream site, as well as 400 and 2500 W/m2 for the same months at the downstream site. It was found that a previous resource assessment, which considered cross-sectionally averaged velocities, substantially underestimated the available power density along the river reach. Finally, the importance of having adequate bathymetric data is demonstrated by comparing field measurements with model simulations.
Bed Forms and Sediment Characteristics along the Thalweg on the Tanana River near Nenana, Alaska, USA  [PDF]
Horacio Toniolo
Natural Resources (NR) , 2013, DOI: 10.4236/nr.2013.41003

Sediment sampling and longitudinal river-bottom surveys were conducted along the thalweg on the Tanana River near the city of Nenana, Alaska, USA, to provide basic information for the engineering design requirements of hydrokinetic devices to be deployed in the area. The study reach was located at approximately 64°33'50\"N and 149°04'W. The Tanana is a large glacier-fed river, with open-water flow conditions from May to October. The river presents a single channel in the study area. Granulometric analyses of sediment moving near the riverbed reveals the coexistence of three distinctive types of sediment along the study reach: 1) nearly uniform fine sand; 2) bimodal distributions containing fine sand and medium gravel; and 3) medium gravel. Preliminary relationships between sediment loads and discharge were developed. Dunes with small superimposed dunes were found along the reach. The basic geometric parameters (i.e., wavelength and height) of dunes were measured, and steepness was calculated. In general, dune wavelength increased with increasing discharge. Dune wavelengths ranged from 41 to 67 m, while small-dune wavelengths ranged from 13 to 16 m. Steepness increased slightly with increasing discharge.


Use of a proteolytic enzyme in cocoa (Theobroma cacao L.) processing
Brito, Edy Sousa de;Pezoa García, Nelson Horacio;Amancio, Allan César;
Brazilian Archives of Biology and Technology , 2004, DOI: 10.1590/S1516-89132004000400008
Abstract: protein hydrolysis using an exogenous protease on cocoa nibs was performed to verify the formation of precursors and the effect on cocoa flavour. an experimental design was used to check the influence of temperature (30 to 70 oc) and enzyme : substrate ratio [e/s] (97.5 to 1267.5 u g-1 of protein). the % degree of hydrolysis (% dh) was affected mainly by [e/s] leading to a 4-fold increase (from 5 to 20 %) after 6 hours of treatment. during cocoa nibs roasting, there was a greater consumption of hydrolysis compounds in the sample treated with protease as compared to the control, indicating their participation in the maillard reaction. an increased perception of chocolate flavour and bitter taste was observed in a product formulated with protease treated cocoa.
Effect of polyphenol oxidase (PPO) and air treatments on total phenol and tannin content of cocoa nibs
Brito, Edy Sousa de;García, Nelson Horacio Pezoa;Amancio, Allan César;
Ciência e Tecnologia de Alimentos , 2002, DOI: 10.1590/S0101-20612002000100008
Abstract: cocoa flavour is greatly influenced by polyphenols. these compounds undergo a series of transformations during cocoa processing leading to the characteristic cocoa flavour. the use of exogenous polyphenol oxidase (ppo) proved to be useful to reduce polyphenol content in cocoa nibs. the effect of a ppo associated or not with air over total phenol and tannin content was evaluated. cocoa nibs were autoclaved and treated with a ppo or water in the absence or presence of an air flow for 0.5, 1, 2 and 3 hours. total phenol content was reduced in ppo or water treatments, but when associated with air there was an increase in phenol content. tannin content was reduced only by the treatment with water and air.
Fragmenta??o mecanica de amêndoas de cupua?u (Theobroma grandiflorum)
Vilalba, Fábio de Albuquerque;Marsaioli Jr, Antonio;Pezoa Garcia, Nelson Horacio;
Ciência e Tecnologia de Alimentos , 2004, DOI: 10.1590/S0101-20612004000300021
Abstract: cupuassu (theobroma grandiflorum) is a native fruit from the brazilian amazon region whose seeds suitably fermented, dried and roasted can be used to manufacture a product similar to chocolate. this work aimed at devising an alternative way of cracking the dried but not roasted kernels by using a roller crusher, followed by using a set of sieves for separating the fractions. the variables studied for determining the nibs (scrapped cotyledons) acquisition yield as well the purity of such material (expressed as percent of shell and embryo fragments) were the moisture of the whole kernel and the differential speed of the double rollers of the crusher. the results confirmed that the moisture of the whole kernel was the variable that most influenced the cracking of kernels. the greater yield obtainment of nibs was reached at the 5% moisture level of the whole kernels. the variation of the double rollers differential speed did not present any significant difference as regards the nibs acquisition yield. as to the percent values of shell and embryo fragments, no studied variables have shown any significant difference on such a response values, even so the results were very well satisfactory, presenting values below the 1.75%. the yield of this alternative process is 90% of the cotyledons acquisition from certain kernels mass. as a conclusion, the process proposed herewith set oneself up as a mechanized alternative, showing good nibs acquirement yield, and percent of shells and embryo below the tolerated value.
Qualidade nutricional das proteínas de cupua?u e de cacau
Lopes, Alessandra Santos;Pezoa-García, Nelson Horacio;Amaya-Farfán, Jaime;
Ciência e Tecnologia de Alimentos , 2008, DOI: 10.1590/S0101-20612008000200001
Abstract: cupuassu has arisen as an important agricultural export product, with widespread market perspectives due to its acceptance amongst regional consumers and those in other brazilian states. the objective of the present study was to evaluate the protein quality of powdered products formulated with roasted cupuassu and cocoa beans. according to the net protein ratio determined in biological trials using diets containing 10% protein in a 50:50 proportion of cupuassu or cocoa:casein, it was shown that cupuassu proteins presented a significantly superior (p < 0.05) biological value as compared to cocoa proteins, promoting a 57.4% greater weight increase in the animals than cocoa proteins. with respect to the daily requirements of children and adults, the amino acid profile of cupuassu proteins presented a better performance than cocoa proteins.
Proteínas da semente de cupua?u e altera??es devidas à fermenta??o e à torra??o
Carvalho, Ana Vania;García, Nelson Horacio Pezoa;Farfán, Jaime Amaya;
Ciência e Tecnologia de Alimentos , 2008, DOI: 10.1590/S0101-20612008000400035
Abstract: cupuacu (theobroma grandiflorum schum) is a native fruit from northern brazil with great economic potential. its productive chain is currently sustained by the pulp market. the seed, treated as a by-product of the pulp industrialization, presents considerably protein content. however, very little or nothing is known on its eletrophoretic profile and amino acids, the main protein fractions and alterations due to the fermentation and toasting. the objective of this study was to characterize protein changes in cupuacu seeds, fermented beans, and roasted beans, through the analysis of the electrophoresis profiles, aminograms, and protein fractionations based on solubility. fermentation and roasting promoted a slight reduction in the total protein and amino acid contents. the seeds and fermented beans presented four main protein bands with 15.5, 20.4, 27.1, and 33.6 kda. the beans submitted to fermentation followed by roasting presented only one strong protein band with an apparent molecular weight of 21.0 kda. the extractions for protein fractionation based on solubility did not result in pure protein fractions. four main bands were observed in all isolated protein fractions. the 21.1 kda band was predominant in all cases. this band is apparently very similar to the albumin fraction of cocoa, whose apparent molecular weight is 21.3 kda.
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