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Search Results: 1 - 10 of 375 matches for " Hor Putchhat "
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Emergence of Community-Associated Methicillin-Resistant Staphylococcus aureus Associated with Pediatric Infection in Cambodia
Kheng Chheng, Sarah Tarquinio, Vanaporn Wuthiekanun, Lina Sin, Janjira Thaipadungpanit, Premjit Amornchai, Ngoun Chanpheaktra, Sarinna Tumapa, Hor Putchhat, Nicholas P. J. Day, Sharon J. Peacock
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0006630
Abstract: Background The incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is rising in the developed world but appears to be rare in developing countries. One explanation for this difference is that resource poor countries lack the diagnostic microbiology facilities necessary to detect the presence of CA-MRSA carriage and infection. Methodology and Principal Findings We developed diagnostic microbiology capabilities at the Angkor Hospital for Children, Siem Reap, western Cambodia in January 2006 and in the same month identified a child with severe community-acquired impetigo caused by CA-MRSA. A study was undertaken to identify and describe additional cases presenting between January 2006 and December 2007. Bacterial isolates underwent molecular characterization using multilocus sequence typing, staphylococcal cassette chromosome mec (SCCmec) typing, and PCR for the presence of the genes encoding Panton-Valentine Leukocidin (PVL). Seventeen children were identified with CA-MRSA infection, of which 11 had skin and soft tissue infection and 6 had invasive disease. The majority of cases were unrelated in time or place. Molecular characterization identified two independent MRSA clones; fifteen isolates were sequence type (ST) 834, SCCmec type IV, PVL gene-negative, and two isolates were ST 121, SCCmec type V, PVL gene-positive. Conclusions This represents the first ever report of MRSA in Cambodia, spread of which would pose a significant threat to public health. The finding that cases were mostly unrelated in time or place suggests that these were sporadic infections in persons who were CA-MRSA carriers or contacts of carriers, rather than arising in the context of an outbreak.
A Prospective Study of the Causes of Febrile Illness Requiring Hospitalization in Children in Cambodia
Kheng Chheng, Michael J. Carter, Kate Emary, Ngoun Chanpheaktra, Catrin E. Moore, Nicole Stoesser, Hor Putchhat, Soeng Sona, Sin Reaksmey, Paul Kitsutani, Borann Sar, H. Rogier van Doorn, Nguyen Hanh Uyen, Le Van Tan, Daniel Paris, Stuart D. Blacksell, Premjit Amornchai, Vanaporn Wuthiekanun, Christopher M. Parry, Nicholas P. J. Day, Varun Kumar
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0060634
Abstract: Background Febrile illnesses are pre-eminent contributors to morbidity and mortality among children in South-East Asia but the causes are poorly understood. We determined the causes of fever in children hospitalised in Siem Reap province, Cambodia. Methods and Findings A one-year prospective study of febrile children admitted to Angkor Hospital for Children, Siem Reap. Demographic, clinical, laboratory and outcome data were comprehensively analysed. Between October 12th 2009 and October 12th 2010 there were 1225 episodes of febrile illness in 1180 children. Median (IQR) age was 2.0 (0.8–6.4) years, with 850 (69%) episodes in children <5 years. Common microbiological diagnoses were dengue virus (16.2%), scrub typhus (7.8%), and Japanese encephalitis virus (5.8%). 76 (6.3%) episodes had culture-proven bloodstream infection, including Salmonella enterica serovar Typhi (22 isolates, 1.8%), Streptococcus pneumoniae (13, 1.1%), Escherichia coli (8, 0.7%), Haemophilus influenzae (7, 0.6%), Staphylococcus aureus (6, 0.5%) and Burkholderia pseudomallei (6, 0.5%). There were 69 deaths (5.6%), including those due to clinically diagnosed pneumonia (19), dengue virus (5), and melioidosis (4). 10 of 69 (14.5%) deaths were associated with culture-proven bloodstream infection in logistic regression analyses (odds ratio for mortality 3.4, 95% CI 1.6–6.9). Antimicrobial resistance was prevalent, particularly in S. enterica Typhi, (where 90% of isolates were resistant to ciprofloxacin, and 86% were multi-drug resistant). Comorbid undernutrition was present in 44% of episodes and a major risk factor for acute mortality (OR 2.1, 95% CI 1.1–4.2), as were HIV infection and cardiac disease. Conclusion We identified a microbiological cause of fever in almost 50% of episodes in this large study of community-acquired febrile illness in hospitalized children in Cambodia. The range of pathogens, antimicrobial susceptibility, and co-morbidities associated with mortality described will be of use in the development of rational guidelines for infectious disease treatment and control in Cambodia and South-East Asia.
Exploring Competitive Strategies of China Ceramic Tile Industrial Cluster in Global Economy  [PDF]
Mei-Hor Lo, Dechang Han
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.23003
Abstract:

In this paper, we discuss the competitive paradigm between globalization and local development in the ceramic tile industrial cluster, based on the Porter’s theory in exploring the factors of the global competitiveness. We analysis the theory of cluster and competitive theory to compare two ceramic tile clusters in different contexts for tracing the mechanism and path constructed ceramic industry international competitiveness and strategy formation. In the study, we discuss what changes come into play addressing the radical changes in world markets, both for ceramic tiles and for surrounding ceramic tile supportive industries. These issues will be discussed with amount of literature reviews through the various perspectives to explore more comprehensive insight to China ceramic tile industry.

Aprendizagem ao longo da vida: boas práticas e inser??o social
Covita,Horácio Mendes;
Análise Psicológica , 2002,
Abstract: long life learning can be seen as a key element of effective citizenship and employability, becoming a priority for non profit organizations and corporate companies agendas, in searching for a better understanding about new learning contexts and providing solutions near citizens needs and availabilities, recognising those non formal learning contexts as critical players for the emergence and development of skills and competences. in this work we argue and discuss initiatives that can actively promote the organizational and work team best practices identification, transfer and appropriation, as organizational transformation processes, with impacts on productivity, competitiveness and vulnerable people inclusion. we also discuss the knowledge resources centres (krc), as support platforms and devices to citizens, namely training bodies and training professionals, empowered and committed with long life learning and improvement skills projects, with added value when are focused on citizens with specific vulnerabilities.
Popper e o processo de ensino-aprendizagem pela resolu??o de problemas
Rodrigues, Horácio Wanderlei;
Revista Direito GV , 2010, DOI: 10.1590/S1808-24322010000100003
Abstract: the paper proposes a method of teaching and a curriculum structure constructed on the epistemological work of karl popper and also elements in problem based learning (pbl). the teaching-learning process for troubleshooting (earp) presented in this paper is divided into method and pedagogical project (earp). the proposed method focuses on a strategy consisting of four stages, all involving the study of issues, seeking a solution through trial and elimination of errors. the pedagogical project includes the elimination of traditional disciplines by organizing the curriculum and has a modular structure for interdisciplinary topics. the text contains, for better visualization of the proposal, a hypothetical grade and the possibilities of organizing time frame.
Solution to the Technical Infrastructure and Economic-Mathematical Methods
Radek Horák
Transactions of the V?B - Technical University of Ostrava. Construction Series , 2010, DOI: 10.2478/v10160-010-0004-5
Abstract: The application of economic-mathematical methods is used to propose a solution to the technical infrastructure because both solving the technical infrastructure and using economic-mathematical methods require economical conducting operations. The proposals can include a lot of solutions but only the most efficient one can be put into practice. That is why the optimal solution to the underground utilities is being looking for.
Flavonoids in prevention of diseases with respect to modulation of Ca-pump function
ubica Horáková
Interdisciplinary Toxicology , 2011, DOI: 10.2478/v10102-011-0019-5
Abstract: Flavonoids, natural phenolic compounds, are known as agents with strong antioxidant properties. In many diseases associated with oxidative/nitrosative stress and aging they provide multiple biological health benefits. Ca2+-ATPases belong to the main calcium regulating proteins involved in the balance of calcium homeostasis, which is impaired in oxidative/nitrosative stress and related diseases or aging. The mechanisms of Ca2+-ATPases dysfunction are discussed, focusing on cystein oxidation and tyrosine nitration. Flavonoids act not only as antioxidants but are also able to bind directly to Ca2+-ATPases, thus changing their conformation, which results in modulation of enzyme activity. Dysfunction of Ca2+-ATPases is summarized with respect to their posttranslational and conformational changes in diseases related to oxidative/nitrosative stress and aging. Ca2+-ATPases are discussed as a therapeutic tool and the possible role of flavonoids in this process is suggested.
Intra-Industry Trade and Labour Market Adjustment in the Automobile Industry
Horácio Crespo Faustino
International Journal of Economics and Finance , 2010, DOI: 10.5539/ijef.v2n4p3
Abstract: This paper examines the effects of increased intra-industry trade on the labour market adjustment costs in Portugal’s automobile industry. Using a static and dynamic panel data approach, the results show a negative correlation between changes of employment and marginal intra-industry trade. These results confirm the smooth adjustment hypothesis (SAH). Whereas most of the empirical studies have tested the SAH considering all of the industries within an economy, the present paper tests the same hypothesis considering solely the reallocation of labour within the automobile industry (between sectors of this industry). The results also suggest that there is no great difference between static and dynamic results. Keywords: Adjustment costs, Automobile industry, Marginal intra-industry trade, Panel data JEL classification: F14; C33.
Interpretácie hriechu v idovskej literatúre v intertestamentárnom období (The Interpretation of the Sin in Judaic Literature and Intertestamentary Period)
Sidonia Horňanová
Ostium , 2008,
Abstract: The aim of the contribution is to acquaint with the issue of origin of evil in the documents of intertestamentary period (the books of Enoch, the Book of Jubilees, Ben Sira and some texts from Qumran). Between the Testaments there was a very lively debate on the origin of sin. There was triple solving of the problem: Through interpretation of mythic account of the origin of evil of the agency of fallen angels; through interpretation of transmission of sin from Adam in paradise and finally through explanation of origin of evil in the Instruction on the Two Spirits in Qumran. In the present in Christian tradition there is the emphasis put on the hereditary transmission of sin from Adam.
Měkky i Národní p írodní rezervace Soos Molluscs (Mollusca) of the Soos National Nature Reserve
Jitka Horá?ková
Malacologica Bohemoslovaca , 2012,
Abstract: The Soos National Nature Reserve nearby Franti kovy Lázně Town (Western Bohemia, Czech Republic) is a spectacular peatbog site with the occurrence of fens on numerous mineral spring effluents, emanations of pure carbon dioxide in mofettes (i.e. false mud volcanoes), parts with saltwater wetlands, and diatomite mantel in its central part. These natural conditions affect general character of all habitats, vegetation and malacocoenoses in the reserve. Altogether, 31 mollusc species were found there, but only two of them are considered as near threatened (Pisidium obtusale and Vertigo substriata). The majority of recorded assemblage was composed of common and generalist mollusc species.
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