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Search Results: 1 - 9 of 9 matches for " Honesty Ganu "
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Population-Based Tuberculosis Disease Prevalence Survey in Ghana: The Role and Lessons Learnt from the Laboratory  [PDF]
Kennedy Kwasi Addo, Samuel Ofori Addo, Christian Bonsu, Ezekiel Mensah, Sarah Edusei, Prosper Dedzo, Michael Amo Omari, Samuel Kudzawu, Honesty Ganu, Samuel Kumah Atiadevie, Frank Adae Bonsu
Journal of Tuberculosis Research (JTR) , 2019, DOI: 10.4236/jtr.2019.72009
Abstract: Background: Bacteriologically-confirmed tuberculosis (TB) cases used in calculating TB prevalence in a country are obtained through laboratory examination of sputum specimens. Objective: This article describes laboratory processing of specimens, results overview, conclusions and key lessons learnt from the perspective of laboratory personnel involved in the conduct of TB disease prevalence survey in Ghana in 2013. Methods: Symptoms screening and Chest X-ray suggestive of TB were used to select participants who produced sputum to confirm TB cases using microscopy, culture and Xpert® MTB/RIF assay (GeneXpert). Results: A total of 15,935 single and paired sputum specimens were received from eligible participants. About half of Ziehl-Nielsen (129/263) and Auramine O (122/246) stained smear positives were scanty positive. Culture positivity rate for Mycobacterium tuberculosis complex was 266/14,994 (1.7%) and 100/15,179 (0.7%) in Mycobacterial Growth Indicator Tube (MGIT) and Lowenstein-Jensen (LJ) media respectively; while non-tuberculous mycobacterium was 294/14,994 (1.96%) and 167/15,179 (1.1%). Total contamination rates in MGIT (5.4%) were higher than in LJ (1.7%). Prevalence of smear positive TB and bacteriologically confirmed TB among adult population (≥15 years) was estimated at 111 (95% CI: 76 - 145) and 356 (95% CI: 288 - 425) per 100,000 population respectively. Conclusions and Lessons Learnt: Direct supervision of specimen collection by well-trained laboratory personnel, timely transportation of specimens from field to laboratory, prompt specimen processing and use of electronic data management systems are essential for a reliable TB disease prevalence survey data. More importantly, strengthening human and logistical capacity of the laboratory must be of utmost priority.
Air Traffic Flow Management
Hrishikesh V. Ganu
Mathematics , 2008,
Abstract: Air Traffic Flow Management is the regulation of air traffic in order to avoid exceeding airport or flight sector capacity in handling traffic, and to ensure that available capacity is used efficiently. We have tried to explore the logic behind the claims by Bertsimas et.al about integral solutions to the LP relaxation of the Traffic Flow Management Problem(TFMP). Polyhedral theory only indicates that the stronger TFMP formulation of Bertsimas et.al might lead to integral solutions in some cases. Our computations indicate that the encouraging results reported by Bertsimas et.al are not merely fortuitous or due to their specific data set. Indeed, we found that the TFMP had integral solutions even in case of artificial data sets generated to include severe conflicts in the flight schedules. In our limited tests with 4-5 scenarios, we obtained non-integral solutions only once. This is of significant practical importance because, the LP relaxation can be solved even on small machines with low memory and processor speed.
A modified stylus for selective brush plating
Gajanam M. Ganu,Subrato Mahapatra
Gold Bulletin , 1987, DOI: 10.1007/BF03214659
Abstract: The modified stylus presented consists of a half cell made from a glass tube. The design has two major benefits: the glass tube forms a reservoir which allows for continuous plating without the need to replenish the electrolyte, and the tip of the stylus can be tapered to a fine straight or curved point, allowing plating of intricate work. If required, a wide-bore stylus is also effective.
Effect of Obesity on Arch Index in Young Adults
Sneha Sameer Ganu,Vrushali Panhale
Online Journal of Health & Allied Sciences , 2013,
Abstract: Background: Excessive increases in weight bearing forces caused by obesity may negatively affect the lower limbs and feet but minimal research has examined the long-term loading effects of obesity on the musculoskeletal system, particularly in reference to the feet. Objectives: The purpose of the study was to investigate the effect of obesity on medial longitudinal arch of foot in young adults. Method: 60 subjects, 30 obese & 30 non obese were assessed for height & weight using standard technique. Radiographic images under static condition were used for calculating the arch index. Result: The arch index of obese subjects was significantly lower than the non obese subjects & there is a negative correlation between the BMI & the arch index. Conclusion: These results suggests that obesity lowers the medial longitudinal arch of foot.
Effects of anticancer drugs on folate disposition and excretion.
Gokhale S,Ganu U,Ambaye R
Journal of Postgraduate Medicine , 1985,
Morphological Analysis of Cryogenic Spray Images
Hrishikesh V. Ganu,B. N. Raghunandan
Physics , 2008,
Abstract: This study gives the development of a new technique for analyzing images of Cryogenic sprays, to estimate the drop-size distribution. It has a sound mathematical basis, in the form of Mathematical Morphology, and we have tried to build up a formulation for a granulometry, starting from the elementary operations of Dilation and Erosion. An axiomatic foundation for granulometry has also been discussed. We have taken an actual LN2 spray photograph for analysis, to illustrate the use of Morphological operations, culminating in a granulometry.
Lipid Profile and Serum Paraoxonase1 Activity in CRF Patients Pre and Posthemodialysis
Nitin S. Nagane1* and Jayshree V. Ganu2
Al Ameen Journal of Medical Sciences , 2011,
Abstract: Chronic renal failure (CRF) is associated with an increased risk of cardiovascular disease (CVD). In the present study, 30 CRF patients undergoing hemodialysis and 50 healthy controls matching in age and sex were included. We have estimated blood urea, serum creatinine, lipid profile and serum Paraoxonase1 (PON1) activity in pre and post hemodialytic samples. HDL-Cholesterol (HDLC) and serum Paraoxonase1(PON1) activity was found to be significantly reduced (P<0.001) in CRF patients as compared to that of controls. However HDL-Cholesterol (HDLC) and Paraoxonase1 (PON1) show significant elevation (P<0.001) post hemodialysis than prehemodialytic samples of CRF patients. The levels of blood urea, serum creatinine, total cholesterol, LDL-Cholesterol (LDLC) and Triglyceride (TG) were significantly elevated (P<0.001) in CRF patients. After hemodialysis these parameters were significantly reduced (P<0.001) as compared to pre hemodialytic samples. The low HDL-Cholesterol (HDLC) and serum Paraoxonase1 (PON1) activity may be responsible factor for cardiovascular disease associated with CRF. Therefore, management of CRF patients by Hemodialysis (HD) has beneficial effect.
Antioxidant and antihyperglycemic potential of methanolic extract of bark of mimusops elengi l. In mice
G. P. Ganu,S. S Jadhav,A. D. Deshpande
International Journal of Phytomedicine , 2011,
Abstract: Ayurveda refers Mimusops elengi L. for the treatment of the diabetes. Considering the traditional claim of M. elengi in management of diabetes and the possible involvement of oxidative stress in pathogenesis of diabetes, the present study was aimed to evaluate the in vitro antioxidant and in vivo antihyperglycemic property of methanolic extract of bark of M. elengi (MEMeOH). In vitro antioxidant activity of MEMeOH was evaluated using reducing power assay, DPPH and hydroxyl radical scavenging assay. MEMeOH offered significant in vitro reducing power capacity and radical scavenging activity. In acute study in alloxan induced diabetes, MEMeOH exhibited significant (p< 0.001) antihyperglycemic effect. The onset of antihyperglycemic effect was observed at 2nd hr; peak activity was demonstrated at 6th hr. The antihyperglycemic effect of MEMeOH 400mg/kg, p.o. was persistent up to 24th hr after drug administration. MEMeOH produced significant (p < 0.01) reduction in elevated glucose levels in glucose loaded non diabetic animals. The onset of action in non diabetic oral glucose tolerance test was found to be at 60th min and peak activity was observed at 120th min after oral glucose load. MEMeOH demonstrated significant (p < 0.01) reduction in elevated glucose levels 2hr before glucose administration and 6 hr after glucose load in oral glucose tolerance test in diabetic animals. MEMeOH has demonstrated antihyperglycemic activity in diabetic as well as non diabetic glucose loaded mice. MEMeOH should be further explored against diabetes and related complications. Keywords: Mimusops elengi; antihyperglycemic, antioxidant, DPPH, diabetic OGTT
Risk Factors for Buruli Ulcer in Ghana—A Case Control Study in the Suhum-Kraboa-Coaltar and Akuapem South Districts of the Eastern Region
Ernest Kenu ,Kofi Mensah Nyarko,Linda Seefeld,Vincent Ganu,Michael K?ser,Margaret Lartey,Benedict Nii Laryea Calys-Tagoe,Kwodwo Koram,Richard Adanu,Oliver Razum,Edwin Afari,Fred N. Binka
PLOS Neglected Tropical Diseases , 2014, DOI: 10.1371/journal.pntd.0003279
Abstract: Background Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans. Its exact mode of transmission is not known. Previous studies have identified demographic, socio-economic, health and hygiene as well as environment related risk factors. We investigated whether the same factors pertain in Suhum-Kraboa-Coaltar (SKC) and Akuapem South (AS) Districts in Ghana which previously were not endemic for BU. Methods We conducted a case control study. A case of BU was defined as any person aged 2 years or more who resided in study area (SKC or AS District) diagnosed according to the WHO clinical case definition for BU and matched with age- (+/?5 years), gender-, and community controls. A structured questionnaire on host, demographic, environmental, and behavioural factors was administered to participants. Results A total of 113 cases and 113 community controls were interviewed. Multivariate conditional logistic regression analysis identified presence of wetland in the neighborhood (OR = 3.9, 95% CI = 1.9–8.2), insect bites in water/mud (OR = 5.7, 95% CI = 2.5–13.1), use of adhesive when injured (OR = 2.7, 95% CI = 1.1–6.8), and washing in the Densu river (OR = 2.3, 95% CI = 1.1–4.96) as risk factors associated with BU. Rubbing an injured area with alcohol (OR = 0.21, 95% CI = 0.008–0.57) and wearing long sleeves for farming (OR = 0.29, 95% CI = 0.14–0.62) showed protection against BU. Conclusion This study identified the presence of wetland, insect bites in water, use of adhesive when injured, and washing in the river as risk factors for BU; and covering limbs during farming as well as use of alcohol after insect bites as protective factors against BU in Ghana. Until paths of transmission are unraveled, control strategies in BU endemic areas should focus on these known risk factors.
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