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Search Results: 1 - 10 of 24082 matches for " Ho Man Tang "
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Research on the allelopathic potential of wheat  [PDF]
Yau Lam, Cho Wing Sze, Yao Tong, Tzi Bun Ng, Sydney Chi Wai Tang, James Chung Man Ho, Qiaoqing Xiang, Xiao Lin, Yanbo Zhang
Agricultural Sciences (AS) , 2012, DOI: 10.4236/as.2012.38119
Abstract: Objective: This paper mainly discusses the Allelopathic potential of Wheat. Methods: This paper is prepared by reviewing the latest academic literatures. Result: The green revolution in the 1960s caused an increase in the demand for food. The agricultural sector and farmers tended to spend more time on the agricultural work but the crop yield was suppressed by the weeds. Hence, the usage of herbicide insecticides, fungicides and others chemicals had been increased. Although herbicides are efficient for weed controls, the continuous uses had gradually stimulated the weeds developing an effecttive resistance to the chemicals. Wheat (Triticum aestivum L.) is known as allelopathic against crops and weeds. Allelopathy of wheat (Triticum aestivum L.) has been extensively examined for its potentials in weeds management. The allelopathic activity of wheat has been attributed to hydroxamic acids, the related compounds and phenolic acids. Therefore, it could effectively reduce herbicide uses in order to maintain an eco-friendly environment and a cost-effective weed control.
How Dark Energy Affects the MOND Theory in Clusters  [PDF]
Man Ho Chan
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.329147
Abstract: Modified Newtonian Dynamics (MOND) is one of the successful theories to explain the dark matter problem in galaxies. However, the data from clusters and the cosmic microwave background (CMB) indicate some dark matter should exist in larger scales. In addition, recent dynamical studies of clusters show that the effect of dark energy should not be ignored in cluster scale. In this article, I will demonstrate how dark energy affects the cluster mass calculation by using MOND. Also, I will show that the calculated cluster mass is consistent with the total matter to baryonic matter ratio obtained by the CMB data.
Gene Mapping via Bulked Segregant RNA-Seq (BSR-Seq)
Sanzhen Liu, Cheng-Ting Yeh, Ho Man Tang, Dan Nettleton, Patrick S. Schnable
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036406
Abstract: Bulked segregant analysis (BSA) is an efficient method to rapidly and efficiently map genes responsible for mutant phenotypes. BSA requires access to quantitative genetic markers that are polymorphic in the mapping population. We have developed a modification of BSA (BSR-Seq) that makes use of RNA-Seq reads to efficiently map genes even in populations for which no polymorphic markers have been previously identified. Because of the digital nature of next-generation sequencing (NGS) data, it is possible to conduct de novo SNP discovery and quantitatively genotype BSA samples by analyzing the same RNA-Seq data using an empirical Bayesian approach. In addition, analysis of the RNA-Seq data provides information on the effects of the mutant on global patterns of gene expression at no extra cost. In combination these results greatly simplify gene cloning experiments. To demonstrate the utility of this strategy BSR-Seq was used to clone the glossy3 (gl3) gene of maize. Mutants of the glossy loci exhibit altered accumulation of epicuticular waxes on juvenile leaves. By subjecting the reference allele of gl3 to BSR-Seq, we were able to map the gl3 locus to an ~2 Mb interval. The single gene located in the ~2 Mb mapping interval whose expression was down-regulated in the mutant pool was subsequently demonstrated to be the gl3 gene via the analysis of multiple independent transposon induced mutant alleles. The gl3 gene encodes a putative myb transcription factor, which directly or indirectly affects the expression of a number of genes involved in the biosynthesis of very-long-chain fatty acids.
Treatment of non-small cell lung cancer in the era of targeted therapy  [PDF]
James Chung-Man Ho
Advances in Lung Cancer (ALC) , 2012, DOI: 10.4236/alc.2012.11001
Abstract: Lung cancer, mostly non-small cell carcinoma (NSCLC), is still a major global problem with devastating outcomes. The majority presents at late stages, in which the chance of cure is minimal. With the better understanding of lung cancer biology, there have been several novel targeted approaches against NSCLC. Anti-angiogenesis has been proven to be an important approach in combination with systemic chemotherapy treatment in NSCLC at the first-line setting. The prototypic monoclonal antibody against vascular endothelial growth factor (VEGF), be- vacizumab, is now approved for clinical use in combination with platinum-based chemotherapy in first-line treatment of advanced non-squamous NSCLC, associated with improved response and survival compared with chemotherapy alone. The most notable example of targeted therapy for lung cancer is epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKI). There have been extensive evidences supporting the superiority of EGFR TKI (like gefitinib or erlotinib) over standard platinum-based doublet chemotherapy in first-line treatment of advanced NSCLC carrying EGFR activating mutations. Almost following the same path as EGFR TKI, a novel target (anaplastic lymphoma kinase, ALK) has been identified recently with a very promising targeted agent (crizotinib) that has already been approved for clinical use in NSCLC carrying ALK rearrangements. Over the past decade, there have been undoubtedly growing armamentaria in the treatment of NSCLC, focusing on personalized and targeted approach.
The differential analytic index in Simons-Sullivan differential K-theory
Man-Ho Ho
Mathematics , 2011, DOI: 10.1007/s10455-012-9325-1
Abstract: We define the Simons-Sullivan differential analytic index by translating the Freed-Lott differential analytic index via explicit ring isomorphisms between Freed-Lott differential K-theory and Simons-Sullivan differential K-theory. We prove the differential Grothendieck-Riemann-Roch theorem in Simons-Sullivan differential K-theory using a theorem of Bismut.
On differential characteristic classes
Man-Ho Ho
Mathematics , 2013, DOI: 10.1017/S1446788714000627
Abstract: In this paper we give explicit formulas of differential characteristic classes of principal $G$-bundles with connections and prove their expected properties. In particular, we obtain explicit formulas for differential Chern classes, differential Pontryagin classes and differential Euler class. Furthermore, we show that the differential Chern class is the unique natural transformation from (Simons-Sullivan) differential $K$-theory to (Cheeger-Simons) differential characters that is compatible with curvature and characteristic class. We also give the explicit formula for the differential Chern class on Freed-Lott differential $K$-theory. Finally we discuss the odd differential Chern classes.
A condensed proof of the differential Grothendieck-Riemann-Roch theorem
Man-Ho Ho
Mathematics , 2011,
Abstract: We give a direct proof that the Freed-Lott differential analytic index is well defined and a condensed proof of the differential Grothendieck-Riemann-Roch theorem. As a byproduct we also obtain a direct proof that the R/Z analytic index is well defined and a condensed proof of the R/Z Grothendieck-Riemann-Roch theorem.
On an index theorem by Bismut
Man-Ho Ho
Mathematics , 2015,
Abstract: In this paper we give a proof of an index theorem by Bismut. As a consequence we obtain another proof of the Grothendieck-Riemann-Roch theorem in differential cohomology.
On the differential Gauss-Bonnet-Chern theorem
Man-Ho Ho
Mathematics , 2015,
Abstract: In this paper we give proofs of the following results: the first one is that every differential character can be represented by differential form with singularities. The second one is the Gauss-Bonnet-Chern theorem for vector bundles taking values in differential characters.
Remarks on flat and differential K-theory
Man-Ho Ho
Mathematics , 2012,
Abstract: In this note we prove some results in flat and differential $K$-theory. The first one is a proof of the compatibility of the differential topological index and the flat topological index by a direct computation. The second one is the explicit isomorphisms between Bunke-Schick differential $K$-theory and Freed-Lott differential $K$-theory.
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