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Search Results: 1 - 10 of 1116 matches for " Histology "
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Tonsillar Lipoma: Report of 2 Cases  [PDF]
Ellouze Sameh, Abid Najla, Chaabane Abir, Chaari Chiraz, Kolsi Saloua, Khabir Abdelmajid, Boudawara Tahya
Open Journal of Pathology (OJPathology) , 2012, DOI: 10.4236/ojpathology.2012.22005
Abstract: Lipomas are benign slow-growing neoplasms composed of mature fat cells. Their occurrence in the oral cavity is rare representing only 1% - 4% of all benign neoplasms of this location. Tonsillar lipomas are extremely rare. Only 15 cases have been reported in the world literature so far. We present two new cases of lipoma affecting the palatine tonsils with a review of the related literature.
Asthma-Like Tracheo-Bronchial Amyloidosis  [PDF]
Fatma Chermiti Ben Abdallah, Hanene Smadhi, Ridha Mahouachi, Amel Chtourou, Sofia Taktak, Ayda Ayadi, Faouzi El Mezni, Ali Ben Kheder
Open Journal of Respiratory Diseases (OJRD) , 2012, DOI: 10.4236/ojrd.2012.22008
Abstract: Localized bronchial Amyloidosis is an uncommon disease of unknown origin. Clinical signs are not specific. Tracheobronchial symptoms are the most frequent. We report a case of a 31 year-old man complaining of asthma-like dyspnea. Bronchoscopy was performed because of ineffectiveness of antiasthmatic treatment, showed a submucosal infiltration with stenosis of both right and left upper bronchi and a complete stenosis of intermediate troncus. Multiple biopsies were performed and concluded to Amyloidosis of AL type. Oral corticosteroids were indicated with clinical improvement.
Effects of Kolaviron, the Major Constituent of Garcinia kola, on the Histology of the Hypothalamus, Pituitary, and Testes Using Adult Male Wistar Rats as a Model Organism  [PDF]
A. U. Obi, P. U. Nwoha
Forensic Medicine and Anatomy Research (FMAR) , 2014, DOI: 10.4236/fmar.2014.23014
Abstract: This study determined the effects of kolaviron on the histology of organs of the hypothalamic-pi- tuitary-gonadal axis, mainly the hypothalamus, pituitary and testis. The aim was to ascertain if its consumption has deleterious effects on these organs. Thirty six adult Wistar rats divided into six groups of six animals each were used and kolaviron administered at 100, 200, 400 and 800 mg/kg body weight. The results showed that gross cellular depletion and desquamation of cells of testis significantly reduced number of cells in the hypothalamus and pituitary (P < 0.05). It significantly reduced the relative brain weight (P < 0.05). These findings suggest that kolaviron can alter the histology of the axis which may impair its reproductive function.
Pathologic Alterations of Canine and Feline Adrenal Glands  [PDF]
Nadja Herbach, Kirstin Wiele, Ulrike Konietschke, Walter Hermanns
Open Journal of Pathology (OJPathology) , 2016, DOI: 10.4236/ojpathology.2016.63017
Abstract: The aim of the study was to determine the frequency and age-dependency of adrenal changes in dogs and cats, which were dissected between 2004 and 2006 at the Institute of Veterinary Pathology, LMU Munich. The adrenal glands of 101 dogs and 159 cats were dissected free from adjacent tissue, weighed, lamellated perpendicular to its longitudinal axis and were embedded in paraffin and plastic for histologic inspection. Ageing cats most frequently showed accessory cortical nodules in the capsule, cortex and medulla, pigment deposition and shock bodies. The appearance of accessory cortical nodules and pigment deposition were linked to the age of the cats and that of shock bodies was linked to infectious diseases. Inflammatory alterations were rare and neoplastic changes were not observed. In dogs, the most frequent alterations were accessory cortical nodules in the capsule, cortex and medulla and circulatory disturbances and there was a significant linkage of the appearance of cortical nodules and pigment deposition and age. Metabolic, inflammatory and tumorous diseases were rarely observed in the dogs examined. In summary, cats and dogs show similar incidental alterations of the adrenals. Clinical relevant adrenal lesions such as atrophy or primary neoplasia were rarely diagnosed.
Histological Profile of ENT and Cervico-Facial Lesions in Mali  [PDF]
Djibril Samaké, Youssouf Sidibé, Fatogoma Issa Koné, Hamidou Niangaly, Kolo Diamouténé, N’faly Konaté, Ngniée Tafo Ghislaine Neuilly, Nagnouma Camara, Kassim Diarra, Abdoul Wahab Haidara, Siaka Soumaoro, Boubacary Guindo, Kadiatou Singaré, Samba Karim Timbo, Mohamed Ké?ta, Alhousseini Ag Mohamed
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2019, DOI: 10.4236/ijohns.2019.81007
Abstract: Aim: Our goal was to determine the histological profile of ENT lesions. Method: We carried out a retrospective and descriptive study in the ENT department and Cervico-Facial Surgery at the university hospital center Gabriel Touré (MALI) from 1995 to 2014. It made it possible to collect 450 cases. Result: We found a male predominance; 51.11% or a sex ratio of 1.04. The mean age of patients was 38.04 years with a standard deviation of 19.49 years and extremes of 3 months and 91 years. Benign tumors were the most frequent (154 cases or 34.22%) including 75 cases of adenomas and 43 cases of papillomas. Cancers accounted for 48.11% (or 153 cases) of all tumors and 34% of lesions. Carcinomas accounted for 81.04%, malignant lymphomas 13.72% and sarcomas 5.22% of cases. Among the 140 cases (31.11%) of inflammatory pseudotumors, we found 12 cases of tuberculosis and 15 cases of rhinoscleroma. Three (3) cases of dysplasia were observed. Conclusion: Interest should be focused on histology in order to initiate appropriate therapy.
An Alternative Approach to Sending All Gallbladders for Histology Following Cholecystectomy?  [PDF]
John-Patrick Devine Byars, Kishore Pursnani
Surgical Science (SS) , 2012, DOI: 10.4236/ss.2012.31003
Abstract: Background: The question of a selective approach to sending all gallbladders for histology following cholecystectomy has been postulated in many journals but as yet no guidelines have been published in light of such concern. This project will attempt to analyse and address the controversy surrounding sending all gallbladders for histology following cholecystectomy. Objective: To ascertain whether there is a feasible and safe alternative to sending all gallbladders to histology following cholecystectomy and to challenge such a hypothesis. Design: Retrospective study. Methods: Analysis of gallbladder pathology reports, patient medical records and computerised test results from cholecystectomies done in the last 5 years within the Lancashire Teaching Hospital Trust. Results: The alternative selective method based on pre-operative investigations and intra-operative macroscopic detail is shown to be significant (P < 0.05). Conclusion: The results from this study show that there is safe and efficient way of selecting which gallbladders are sent for histology based on age, pre-surgical suspicion and intra-operative macroscopic abnormalities.
Contribution of Immunohistochemistry in the Diagnosis of Lymphomas  [PDF]
Daouda Kone, Yao Nicaise Atimere, Zana Ismael Coulibaly, Ulrich Acko, Sogbety Eric Diomande, Maimouna Toure, Pr Aissata Tolo
Open Journal of Blood Diseases (OJBD) , 2018, DOI: 10.4236/ojbd.2018.81003
Abstract: Objective: Making the interest of using immunohistochemistry clear in addition to histological test in the diagnosis of lymphomas. Methods: This is a retrospective study from January 2011 to June 2013 involving 18 cases of lymphomas collected in the teaching hospitals of Treichville and Yopougon. Results: 1) 38.88% diagnosis of LMNH B large-cell in histology against 38.88% LDGCB with IHC. 2) 11.11% diagnosis of LMNH small cell in histology against 11.11% with IHC. 3) 5.55% diagnosis of T lymphoma in histology against 27.77% diagnosis of T lymphoma with IHC. 4) 5.55% diagnosis of follicular lymphoma in histology against 11.11% diagnosis of LF with IHC. 5) 11.11% diagnosis of Burkitt lymphoma in histology against 5.55% diagnosis of LB with IHC. 6) 5.55% diagnosis of medullary hypoplasia in histology against 5.55% diagnosis of Hodgkin’s disease. Our results confirm the contribution of immunohistochemistry in the diagnosis of lymphomas in addition to histological test. This is striking, especially as there is 27.77% of T lymphoma with immunohistochemistry against only 5.55% with histology.
Sevda S?ker
Dicle Medical Journal , 2006,
Abstract: The celebrated 2nd century Greek physician Galen who lived and worked in Rome first used the word ganglion to denote a nerve complex. Ganglion still is used to refer to an aggregation of peripheric nerve cell bodies. In this article, structures and functions of ganglion is reviewed.
Local Cell Mediated Immune Reaction in Primary Obstructive Male Infertility  [PDF]
Anil Kumar Sarda, Shweta Aggarwal Bhalla, Durgatosh Pandey, Shyama Jain
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.21008
Abstract: Increased intra-epididymal pressure due to obstruction causes a breach in the epididymal lining exposing the highly antigenic sperms to the interstitium. When the exposure is small and intermittent, it is likely to induce a local humoral response which may affect sperm maturation and also react with the epididymal epithelium producing irreversible histological changes. The present study on 30 patients of primary obstructive infertility found direct and indirect evidence of the production of antisperm antibodies locally. ELISA for antisperm antibodies was positive in the epididymal fluid in 16/30 (53%) of the patients. Indirect evidence of the role of local antigen-antibody reaction in the epididymis is apparent in 22/30 (73%) patients who had a lymphocytic infiltrate. The local presence of antisperm antibodies in the epididymal fluid correlated well with the presence of lymphocytic infiltration in the interstitium (p < 0.05). In our study 16/30 patients had a positive ELISA for antisperm antibody and all these patients had interstitial lymphocytic infiltration. In addition eight patients with a negative ELISA also showed interstitial lymphocytic infiltration. Thus 22/30 (73%) patients had an evidence of a local immune reaction directly in the form of a positive ELISA for antisperm antibodies in the epididymal fluid and / or indirect evidence in the form of lymphocytic infiltrate in the interstitium. None of the five controls had either a positive ELISA or lymphocytic infiltrate, this difference was found to be statistically significant (p < 0.005).
The Recurrence Rate in Meningiomas: Analysis of Tumor Location, Histological Grading, and Extent of Resection  [PDF]
Konstantinos Violaris, Vasileios Katsarides, Pavlos Sakellariou
Open Journal of Modern Neurosurgery (OJMN) , 2012, DOI: 10.4236/ojmn.2012.21002
Abstract: Background: Purpose of this study was to evaluate various parameters of meningioma after surgical treatment and analyze predictive factors for recurrence. Methods: During 1992-2007, 353 patients were operated for intracranial meningioma in our department. They were followed since, and related data were combined with parameters such as tumor histology (WHO system), tumor location and the extent of tumor resection (Simpson’s scale). The results were analyzed with respect to tumor reappearance. This study was approved by the ethics committee of G. Papanikolaou Hospital. Results: The mean follow up period was 6.45 years. The overall percentage of recurrence was 21.52%. Grade 1 meningiomas (benign) recurred at a rate of 19.1%, grade 2 tumors (atypical) showed 41.7% rate of recurrence and grade 3 meningiomas (malignant) recurred at a rate of 75%. Tumor histopathology was not significant to recurrence (p > 0.001). The location of meningiomas was not found to be significant to recurrence (p > 0.001). Complete tumor resection was accomplished in 269 patients (76.2%). Incomplete resection (Simpson grades 2-5) took place in 84 cases (23.8%). The recurrence rate after complete resection was 13.8%, while the rate for cases with incomplete resection was 46.7%. The extent of removal was significantly associated with recurrence (p < 0.001). Conclusions: Tumor recurrence was observed at 21.5% of patients in our series of intracranial meningioma surgery. The rate of recurrence was related primarily to the extent of surgical removal. Neither tumor site, nor tumor histology were predictive factors for recurrence (ma-lignant meningiomas excluded).
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