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Search Results: 1 - 10 of 256 matches for " Hilde Brems "
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Ethiopia before the United Nations treaty monitoring bodies
E. Brems
Afrika Focus , 2007,
Abstract: Among the many human rights conventions adopted by the UN, seven are known – together with their additional protocols – as the coreinternational human rights instruments:- The International Convention on the Elimination of All Forms of Racial Discrimination;- The International Covenant on Civil and Political Rights;- The International Covenant on Economic, Social and Cultural Rights;- The Convention on the Elimination of all Forms of Discrimination against Women;- The Convention against Torture and other Cruel, Inhuman or Degrading Treatment or Punishment;- The Convention on the Rights of the Child;- The International Convention on the Protection of the Rights of all Migrant Workers and Members of their Families.The main international control mechanism under these conventions is what may be considered the standard mechanism in internationalhuman rights protection: state reporting before an international committee. An initial report is due usually one year after joining thetreaty and afterwards, reports are due periodically (every four or five years). The international committees examine the reports submitted bythe state parties. In the course of this examination they include information from other sources, such as the press, other United Nationsmaterials or NGO information. They also hold a meeting with representatives of the state submitting the report. At the end of thisprocess the committee issues 'concluding observations' or 'concluding comments'. This paper focuses on the experience of one state –Ethiopia - with the seven core human rights treaties. This should allow the reader to gain insights both into the human rights situation in Ethiopia and in the functioning of the United Nations human rights protection system.
Enkele notities over literaire kritiek en het internet
Brems, Elke
Neerlandistiek.nl , 2007,
Pathogenesis of vestibular schwannoma in ring chromosome 22
Ellen Denayer, Hilde Brems, Paul de Cock, Gareth D Evans, Frank Van Calenbergh, Naomi Bowers, Raf Sciot, Maria Debiec-Rychter, Joris V Vermeesch, Jean-Pierre Fryns, Eric Legius
BMC Medical Genetics , 2009, DOI: 10.1186/1471-2350-10-97
Abstract: We report on a female patient with a ring chromosome 22 presenting with severe mental retardation, autistic behaviour, café-au-lait macules and facial dysmorphism. Peripheral blood lymphocytes were karyotyped and array CGH was performed on extracted DNA. At the age of 20 years she was diagnosed with a unilateral vestibular schwannoma. Tumour cells were analyzed by karyotyping, array CGH and NF2 mutation analysis.Karyotype on peripheral blood lymphocytes revealed a ring chromosome 22 in all analyzed cells. A 1 Mb array CGH experiment on peripheral blood DNA showed a deletion of 5 terminal clones on the long arm of chromosome 22. Genetic analysis of vestibular schwannoma tissue revealed loss of the ring chromosome 22 and a somatic second hit in the NF2 gene on the remaining chromosome 22.We conclude that tumours can arise by the combination of loss of the ring chromosome and a pathogenic NF2 mutation on the remaining chromosome 22 in patients with ring chromosome 22. Our findings indicate that patients with a ring 22 should be monitored for NF2-related tumours starting in adolescence.Ring chromosome 22 [r(22)] is a rare human constitutional abnormality. A distinct characteristic phenotype has not been delineated, but frequently reported features are delayed motor development, severe speech disability, hypotonia and microcephaly. In addition growth retardation, ataxia and seizures or abnormal EEG can be observed. Dysmorphic features are variable and mostly mild. Epicanthal folds, full eyebrows and large ears have been reported most frequently [1-4]. Aggressive behaviour as well as autistic disorder and hyperactivity are relatively common [1,3,4]. Internal organ involvement is rather rare,[3] except for central nervous system malformations [2]. The variable clinical presentation in carriers of a r(22) has been attributed to variable breakpoints and dynamic mosaicism. In common with other ring chromosomes, r(22) is assumed to arise from breakage and subsequent fusion of
Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/β-Catenin Pathway in a Drosophila Model for Intellectual Disability
Joke Vandewalle, Marion Langen, Marlen Zschaetzsch, Bonnie Nijhof, Jamie M. Kramer, Hilde Brems, Marijke Bauters, Elsa Lauwers, Mohammed Srahna, Peter Marynen, Patrik Verstreken, Annette Schenck, Bassem A. Hassan, Guy Froyen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0081791
Abstract: We recently reported that duplication of the E3 ubiquitin ligase HUWE1 results in intellectual disability (ID) in male patients. However, the underlying molecular mechanism remains unknown. We used Drosophila melanogaster as a model to investigate the effect of increased HUWE1 levels on the developing nervous system. Similar to the observed levels in patients we overexpressed the HUWE1 mRNA about 2-fold in the fly. The development of the mushroom body and neuromuscular junctions were not altered, and basal neurotransmission was unaffected. These data are in agreement with normal learning and memory in the courtship conditioning paradigm. However, a disturbed branching phenotype at the axon terminals of the dorsal cluster neurons (DCN) was detected. Interestingly, overexpression of HUWE1 was found to decrease the protein levels of dishevelled (dsh) by 50%. As dsh as well as Fz2 mutant flies showed the same disturbed DCN branching phenotype, and the constitutive active homolog of β-catenin, armadillo, could partially rescue this phenotype, our data strongly suggest that increased dosage of HUWE1 compromises the Wnt/β-catenin pathway possibly by enhancing the degradation of dsh.
Gasification of plastic waste as waste-to-energy or waste-to-syngas recovery route  [PDF]
Anke Brems, Raf Dewil, Jan Baeyens, Rui Zhang
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.56086

The disposal of plastic solid waste (PSW) has become a major worldwide environmental problem. New sustainable processes have emerged, i.e. either advanced mechanical recycling of PSW as virgin or second grade plastic feedstock, or thermal treatments to recycle the waste as virgin monomer, as synthetic fuel gas, or as heat source (incineration with energy recovery). These processes avoid land filling, where the non-biodegradable plastics remain a lasting environmental burden. Within the thermal treatments, gasification and pyrolysis gain increased interest. Gasification has been widely studied and applied for biomass and coal, with results reported and published in literature. The application to the treatment of PSW is less documented. Gasification is commonly operated at high temperatures (> 600to 800) in an air-lean environment (or oxygen-deficient in some applications): the air factor is generally between 20% and 40% of the amount of air needed for the combustion of the PSW. Gasification produces mostly a gas phase and a solid residue (char and ashes). The use of air introduces N2 in the product gases, thus considerably reducing the calorific value of the syngas, because of the dilution. The paper will review the existing literature data on PSW gasification, both as the result of laboratory and pilot-scale research. Processes developed in the past will be illustrated. Recently, the use of a sequential gasification and combustion system (at very high temperatures) has been applied to various plastic-containing wastes, with atmospheric emissions shown to be invariably below the legal limits. Operating results and conditions will be reviewed in the paper, and completed with recent own lab-scale experimental results. These results demonstrate that gasification of PSW can be considered as a first order reaction, with values of the activation energy in the order of 187 to 289 kJ/mol as a function of the PSW nature.

Recycling and recovery of post-consumer plastic solid waste in a European context
Brems Anke,Baeyens Jan,Dewil Raf
Thermal Science , 2012, DOI: 10.2298/tsci120111121b
Abstract: The disposal of waste plastics has become a major worldwide environmental problem. The USA, Europe and Japan generate annually about 50 million tons of post-consumer plastic waste, previously landfilled, generally considered as a non-sustainable and environmentally questionable option. Landfill sites and their capacity are, moreover, decreasing rapidly, and legislation is stringent. Several European Directives and US legislation concern plastic wastes and the required management. They are briefly discussed in this paper. New processes have emerged, i.e., advanced mechanical recycling of plastic waste as virgin or second grade plastic feedstock, and thermal treatments to recycle the waste as virgin monomer, as synthetic fuel gas, or as heat source (incineration with energy recovery). These processes avoid land filling, where the non-biodegradable plastics remain a lasting environmental burden. The paper reviews these alternative options through mostly thermal processing (pyrolysis, gasification and waste-to-energy). Additional research is, however, still needed to confirm the potential on pilot and commercial scale. [Acknowledgments. The research was partly funded by the Fundamental Research Funds for the Central Universities RC1101 (PR China) and partly funded by Project KP/09/005 (SCORES4CHEM Knowledge Platform) of the Industrial Research Council of the KU Leuven (Belgium).]
Sobre a nefrosclerose maligna
Adler, Hilde;
Memórias do Instituto Oswaldo Cruz , 1941, DOI: 10.1590/S0074-02761941000100007
Abstract: 1o - das aus den oeffentlichen krankenh?usern von rio de janeiro stammende sektionsmaterial umfasst einen betr?chtlichen prozentzatz von individuen schwarzer und gemischter rasse. es besteht durchweg aus angeh?rigen der sozial und oekonomisch niedersten bev?lkerungsschichten der stadt und ihrer vororte, die gemessen am standard der gesamtbev?lkerung unter den dürftigsten hygienischen bedingungen leben. so fanden sich unter 212 autopsien aus dem anfall der pathologisch-anatomischen abteilung des institutes oswaldo cruz im jahr 1920 bei 111 f?llen schwarze oder mischlinsfarbe protokolliert, (52,3%). unter 349 sektionen der gleichen abteilung im jahr 1938 waren 184 (= 52,7%) von individuen von schwarzer oder gemischter rasse. ein derartiges material bietet guenstige bedingungen fuer die untersuchung der bedeutung der rassenzugehoerigkeit als aetiologischem und pathogenem faktor fuer bestimmte affektionen, bei welchen sie in der literatu in diesem sinn angeführt worden ist. 2o - unter 1080 sektionen von indiduen m?nnlichen geschlechts jeder altersstufe aus dem material der gleichen abteilung der jahre 1918-1926 fanden sich bei 214 faellen syphilitische befunde protokolliert. (19,8% der faelle.) 129 (12%) wiesen eine aortitis oder arteritis syphilitica auf. 3o - das histologische material einer serie von 528 autopsien von individuen im alter unter 40 jahren wurde auf das vorkommen der fuer nephrosclerose maligna (fahr) typisch erachteten pathologischen veraenderungen untersucht. es wurden 4 faelle festgestellt, die das bild dieser nephropathie zeigten. unter den 528 individuen dieser gruppe waren 244 weisse, (46,2%) 274 schwarze oder mischlinge (51,8%) bei 10 war die rassenzugehoerigkeit nicht ersichtlich. 4o - unter heranziehung von 6 weiteren faellen aus anderen serien von sektionen der letzten 4 jahre bel?uft sich die gesamtzahl der mikroskopisch festegestellen faelle von nephrosclerose maligna unter dem material der pathologisch-anatomischen abteilung des institutes
La Construcción Preposicional Con Mirar: Un Análisis Sintáctico-Semántico
Boletin de Linguistica , 2006,
Abstract: this paper examines the prepositional construction with the spanish verb mirar "to look". the high frequency of the intransitive construction "mirar + locative prepositional phrase (pp)" evidences the affinity between mirar and the semantic field of motion verbs. on the basis of an empirical analysis of authentic text material, light is shed upon the hybrid statute of the locative pps that occur with mirar. it is shown that, depending on their meaning, these locative pps take on different syntactic functions. three semantic categories, which display their own syntactic behaviour, can be distinguished: i) the dynamic locative pps that indicate the object of perception or percept (prepositional complement); ii) the dynamic pps that denote the trajectory or path of gaze (prepositional complement or adjunct) and iii) the static pps that help localize the perceiver or the percept (adjunct).
Book Review: International focus group research: a handbook for the health and social sciences, by Monique M. Hennink.
Hilde Jakobsen
Graduate Journal of Social Science , 2010,
Universal Human Rights and Cultural Diversity
Hilde Hey
Human Rights & Human Welfare , 2001,
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