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Search Results: 1 - 10 of 550675 matches for " Hesham A. F. Salem "
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Non-invasive prediction of endometriosis revisited; 3 biomarkers as Angiopoietin-2, Interleukin-1β and Vascular Endothelial Growth Factor  [PDF]
Hoda Abdel Moety, Gihan I. Khalil, Rania M. El Sharkawy, Marwa K. El Ghandour, Fady S. Moiety, Hesham A. F. Salem
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.37095
Abstract:

Introduction: Endometriosis affects up to 1 every 5 women at their reproductive age, with variable and complex symptomatology. Patients may be asymptomatic but may have pain episodes or subfertility. Its negative impact is on patients’ health and quality of life. Objective: it was to investigate the serum and peritoneal fluid (PF) concentrations of Angiopoietin- 2, Interleukin-1β, and Vascular Endothelial Growth Factor, aiming to evaluate their diagnostic performance in endometriosis. Methods: Serum and peritoneal fluid samples were taken from 112 women undergoing laparoscopy for infertility, pelvic pain or adnexal masses. 61 diagnosed with endometriosis and 51 controlled. Primary outcome was to estimate serum and PF concentrations of Angio-2, IL-1β and VEGF and secondarily correlate these concentrations to disease stages thus assuming their diagnostic potential. Results: Significant differences were found between patients and control as regards serum and PF concentration of all studied markers except serum IL-1β. Serum Angio-2 and PF VEGF showed a significantly higher level in more advanced stages of endometriosis. PF VEGF showed a positively significant correlation with the stage of the disease, spearman coefficient t = 0.442 p = 0.014. PF concentrations of Angio-2 and Serum VEGF did not show significant pattern changes with stage-related levels. Diagnostic potential of serum and PF concentrations of the 3 markers were assessed by the ROC curve. Angio-2 proved an excellent diagnostic ability for endometriosis. PF and serum VEGF proved an equal diagnostic performance, whereas, PF IL-1β was the least efficient. Based on the results, we suggested preliminary serum threshold values for these markers to be used as diagnostic or follow-up landmarks with relatively acceptable sensitivity, specificity, positive and negative predictive values. Conclusion: Non-invasive predictive biomarkers for endometriosis were Serum Angio-2, IL-1β, and VEGF independently or in combination with the estimated threshold values. Serum Angio-2 merit is considered as a novel marker for endometriosis due to its diagnostic power.

Analytical Study for the Charge-Transfer Complexes of Pregabalin
Hesham Salem
Journal of Chemistry , 2009, DOI: 10.1155/2009/194653
Abstract:
Low Dose Gamma Irradiation Modifies the Effect of L-Carnitine,Curcumin, Garlic Powder and Green tea Extract on Doxorubicin-Induced Nephropathy in Rats
Rasha R. Radwan*, Esmat A. Shaban*, Hesham A. Salem and Sanaa A. Kenawy
Egyptian Journal of Hospital Medicine , 2010,
Abstract: The possible protective potential of exposure to low dose of radiation in presence or absence of L-carnitine, curcumin, garlic powder or green tea extract was examined in the present study on doxorubicin (DOX)-induced experimental nephropathy in rats. Preliminary study was carried out to select the suitable dose of DOX to induce nephrotoxicity. In the current experiment 5 mg/kg, i.p. was selected as a single dose to induce nephrotoxicity during 15 days. The possible modulating effect of L-carnitine, curcumin, garlic powder or green tea extract on kidney function was examined. Animals were subdivided into three sets. Three groups of the 1st set were exposed to radiation at a single dose level of 0.3 Gy then received DOX, 1, 3 or 7 days postirradiation respectively. The groups of 2nd set daily received L-carnitine (40 mg/kg, i.p.), curcumin (50 mg/kg, i.p.), garlic powder (100 mg/kg, p.o.) and green tea extract (300 mg/kg, p.o.) daily for two weeks before induction of nephropathy. Groups of the 3rd set received the same doses of drugs then were injected with DOX, 1, 3 or 7 days following irradiation respectively. Two groups of animals, one of them received saline and served as normal and the other received DOX and served as nephropathic group were included in 1st, 2nd as well as 3rd set. Fifteen days following DOX administration, serum was collected and the animals were then sacrificed. Serum creatinine, urea and uric acid were evaluated. Data revealed that, a single DOX dose (5 mg/kg) induced marked acute nephrotoxicity manifested as significant increase in the activities of serum creatinine, urea as well as uric acid. Interestingly, pre-exposure to radiation at a dose level of 0.3 Gy, 1 or 3 days before DOX injection exhibited significant improvement in the above altered mentioned parameters. However, exposure to low dose radiation 7 days prior to DOX administration did not show a protective effect. Moreover, pretreatment with L-carnitine, curcumin, garlic powder or green tea extract in rats unexposed or exposed to radiation before DOX administration ameliorated, to a great extent, the effects induced by DOX. The present findings suggest that exposure to a single low dose of radiation (0.3 Gy) one day before DOX administration is a promising approach for maximizing the nephroprotective effects of L-carnitine, curcumin, garlic powder or green tea extract with minimal adverse effects of DOX.
Role of Surgery in Stages II and III Pediatric Abdominal Non-Hodgkin Lymphoma: A 5-Years Experience
Amany M. Ali,Heba A. Sayd,Hesham M. Hamza,Mohamed A. Salem
Cancers , 2011, DOI: 10.3390/cancers3021593
Abstract: Abdominal Non-Hodgkin lymphomas (NHL) are the most common extra nodal presentation of pediatric NHL. Our aim is to assess the role of surgery as a risk factor and to evaluate the impact of risk-adjusted systemic chemotherapy on survival of patients with stages II and III disease. This study included 35 pediatric patients with abdominal NHL treated over five years at South Egypt Cancer Institute (SECI), Assiut University, between January 2005 and January 2010. The data of every patient included: Age, sex, and presentation, staging work up to determine extent of the disease and the type of resection performed, histopathological examination, details of chemotherapy, disease free survival and overall survival. The study included 25 boys and 10 girls with a median age of six years (range: 2.5:15). Thirty patients (86%) presented with abdominal pain, 23 patients (66%) presented with abdominal mass and distention, 13 patients (34%) presented with weight loss, and intestinal obstruction occurred in six patients (17%). The ileo-cecal region and abdominal lymph nodes were the commonest sites (48.5%, 21% respectively). Burkitt's lymphoma was the most common histological type in 29 patients (83%). Ten (28.5%) stage II (group A) and 25 (71.5%) stage III (group B). Complete resections were performed in 10 (28.5%), debulking in 6 (17%) and imaging guided biopsy in 19 (54%). A11 patients received systemic chemotherapy. The median follow up duration was 63 months (range 51-78 months). The parameters that significantly affect the overall survival were stage at presentation complete resection for localized disease. In conclusion, the extent of disease at presentation is the most important prognostic factor in pediatric abdominal NHL. Surgery is restricted to defined situations such as; abdominal emergencies, diagnostic biopsy and total tumor extirpation in localized disease. Chemotherapy is the cornerstone in the management of pediatric abdominal NHL.
Performance Enhancement for Adaptive Beam-Forming Application Based Hybrid PSOGSA Algorithm  [PDF]
Ahmed Magdy, Osama M. EL-Ghandour, Hesham F. A. Hamed
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2015, DOI: 10.4236/jemaa.2015.74014
Abstract: Recently researchers were interested in hybrid algorithms for optimization problems for several communication systems. In this paper, a novel algorithm based on hybrid PSOGSA technique (combination of Gravitational Search Algorithm and Particle Swarm Optimization) is presented to enhance the performance analysis of beam-forming for smart antennas systems using N elements for Uniform Circular Array (UCA) geometry. Complex excitations (phases) of the array radiation pattern are optimized using hybrid PSOGSA technique for a set of simultaneously incident signals. Our results have shown tremendous improvement over the previous work was done using Uniform Linear Array (ULA) geometry and standard GSA in terms of normalized array factor and computational speed for normalized fitness values.
Performance Analysis on a Dual External Cavity Tunable Laser ECTL Source  [PDF]
Ahmed Fawzy, Osama M. El-Ghandour, Hesham F. A. Hamed
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2015, DOI: 10.4236/jemaa.2015.74015
Abstract: This paper presents the diffraction effects on the performance of a dual external cavity tunable laser source, whose external cavities are constructed by micro electro mechanical systems (MEMS). One of the main problems in these structures is the optical diffraction as the emitting surface of the laser diode is usually quite limited in the transverse directions. The emitted beam diffracts rapidly in the air and only a small amount of light is coupled back to the source that usually limits the tuning range of the source. Device characteristics such as tuning range, wavelength shift and sensitivity are evaluated. New expression is used and multiple reflections inside external cavities are considered. The simulation results have shown that single external cavity has limited tuning range. It is shown that multiple reflections have significant effect in our model. To get a better engineering for the dual ECTL dimensions, diffraction effects must be taken into account.
Hydro Matrix Power Wheels Generate More than 5 GW/h from Main Branch Canals (River Nile) in Egypt  [PDF]
Hesham F. A. Hamed, Ahmed M. Kassem, Medhat E. M. Ali
Journal of Power and Energy Engineering (JPEE) , 2016, DOI: 10.4236/jpee.2016.43007
Abstract: In this paper, a new hydromatrix power wheels generation unit is presented. This presented hydromatrix power unit is aimed to convert the water movement in the main river branches into electrical power. It is found that the generated power based on the proposed hydromatrix power can be generated about 5 GW/h in Egypt. The proposed hydromatrix power unit based on the under shot water wheel type and the generated electrical power using this proposed unit is calculated at head; difference equal to 1 meter is presented.
Cement Kiln Dust Chemical Stabilization of Expansive Soil Exposed at El-Kawther Quarter, Sohag Region, Egypt  [PDF]
Hesham A. H. Ismaiel
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.410139
Abstract:

This work dealt with a chemical stabilization of an expansive high plastic soil of Pliocene deposits exposed at El-Kawther quarter using cement kiln dust (CKD) and cement kiln dust with lime (L) to reduce their swelling and improve their geotechnical properties. Several specimens of the studied expansive soil were collected from El-Kawther quarter. Chemical analysis of the used cement kiln dust and the lime was conducted. Microstructural changes were examined using scanning electron microscope (SEM) before and after chemical treatment of the studied soil. Geotechnical properties including plasticity, compaction parameters, unconfined compressive strength (qu), ultrasonic velocities and free swelling of the studied soil were measured before and after the treatment. An optimum content of the cement kiln dust was 16% (CKD). The optimum content of the cement kiln dust with the lime was 14% (CKD) with 3% (L) according to pH-test. The results showed that the addition of cement kiln dust and cement kiln dust with lime led to a decrease in maximum dry density and an increase in optimum water content. Unconfined compressive strength values were increased using cement kiln dust and cement kiln dust with lime at 7 days curing time. Ultrasonic longitudinal (Vp) and shear (Vs) velocities values were also increased by addition of the cement kiln dust and the cement kiln dust with lime at 7 days curing time. Increment of the curing time from 7 to 28 days led to an increase in both unconfined compressive strength and ultrasonic velocities values. Free swelling percent of the studied soil was reduced from 80.0% to 0.0% after the treatment.

Geotechnical Investigations of Sub-Grade Soils at the Connector Road, New Tiba City, Luxor, Egypt  [PDF]
Hesham A. H. Ismaiel
Open Journal of Geology (OJG) , 2018, DOI: 10.4236/ojg.2018.812069
Abstract: The presented study dealt with geotechnical investigations on the sub-grade soils along the connector road between the electrical transformer station and the industrial city, New Tiba city, Luxor, to classify these soils and to examine their geotechnical behavior and their proportionality for constructing the road at the study area. One of the most important aims of this work was to determine the problematic sub-grade soils and to recommend the suitable reclamation. To achieve these goals sixty disturbed samples from six mechanical wash drilling boreholes and three undisturbed samples from three open pits were collected. The studied soils were belonged to Quaternary age. Gradation parameters (coefficient of uniformity, Cu and coefficient of concavity, Cc), plasticity, California bearing ratio (CBR), proctor density and free swelling percent of the studied soils were measured. PH-value, dissolved chloride, dissolved sulfate, calcium carbonate, total carbonate, and total dissolved salts were determined. The results pointed that the studied Quaternary soils along the study road were mainly composed of gravels, sands and clayey sands. The studied gravels were classified as poorly graded gravels (GP) according to Unified Soil Classification System (USCS) and as A-1-b according to American Association of State Highway and Transportation Official (AASHTO). The studied sands were classified as well graded sands (SW) according to USCS and as A-1-a according to AASHTO. The results showed also that the sub-grades at boreholes no. 1, 3, 4, 5, and 6 were excellent to good and the sub-grade at boreholes no. 2 was fair to poor. Free swelling percent of the studied clayey sand soils was ranging from 30% to 80% and they were classified as low to medium grade expansive soil. Replacement and/or chemical stabilization (using lime and/or cement kiln dust) of the problematic clayey sands soils were suggested to reduce their swelling and to prevent the possible heave.
Geotechnical Investigations and Estimation of Earthquakes Factors at an Industrial Qift City, Qena, Egypt  [PDF]
Hesham A. H. Ismaiel
Journal of Geoscience and Environment Protection (GEP) , 2018, DOI: 10.4236/gep.2018.612010
Abstract: The present work dealt with the estimation of geotechnical parameters and earthquakes factors of poultry feed factory project constructing at an industrial Qift city, Qena, Egypt. The geotechnical parameters were including gradation parameters, shear velocity (Vs), shear parameters (frictional angle and cohesion), and allowable bearing capacity. The earthquakes factors were including soil coefficient (S), limits of constant value for elastic response spectrum (TB and TC), and specified value for begin of the constant displacement spectrum (TD). The present study was interested also in an estimation of design ground acceleration (ag). To achieve these objectives, five mechanical wash boreholes were conducted at ten meter depth. Fifty disturbed samples were collected. Geotechnical laboratory tests were carried out like grain size analyses, direct shear box, and shear velocity (Vs). Standard penetration test (SPT) as geotechnical field test was conducted. The results showed that the studied soils were classified as well graded and poorly graded sands (SP and SW) according to the unified soil classification system (USCS). The earthquakes factors including S, TB, TC, and TD were 1.80, 0.10, 0.30, and 1.20 respectively. The ag-value of the studied area was 0.10. According to Egyptian code for vibration and dynamic load foundations, the studied project area was classified as low potential seismic. According to Egyptian code for shallow foundation, the allowable bearing capacity of the studied sands ranging from 1.5 to 3 kg/cm2 at shallow foundation width must be not less than one meter. Shallow foundations like isolated footing or structural mat were recommended.
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