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Search Results: 1 - 10 of 151587 matches for " Henrique F. Pauna "
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Auditory Dysfunction in Aging: Prospects for Stem Cell Therapy  [PDF]
Henrique F. Pauna, Maria Stella A. Amaral, Steven K. Juhn, Walter C. Low, Miguel A. Hyppolito
Advances in Bioscience and Biotechnology (ABB) , 2019, DOI: 10.4236/abb.2019.102002
Abstract: Age-related hearing loss is the most common cause of adult auditory dysfunction. It is characterized by bilateral, progressive auditory deterioration associated with the aging process. There currently are limited options for the treatment as hearing aids or cochlear implants. To establish novel strategies for the treatment of this entity, it is crucial to elucidate the mechanisms of age-related hearing loss. Its etiology is believed to be multifactorial including both intrinsic and extrinsic factors. Oxidative damage, as seen in other aging organs systems, may play an essential role in the pathogenesis of the age-related hearing loss. Studies on animal models and human temporal bones have indicated a close relationship between degeneration of the cochlear lateral wall and hearing loss. Additional therapies that may prove beneficial in the treatment of age-related hearing loss include stem cell therapy, which we intend to review in this manuscript.
The Influence of Sound Deprivation on Audiologic Outcomes after Cochlear Implantation  [PDF]
Maria Stella Arantes do Amaral, Ana Cláudia Mirandola Barbosa Reis, Henrique F. Pauna, Sarah C. Bernal, Eduardo T. Massuda, Miguel Angelo Hyppolito
International Journal of Clinical Medicine (IJCM) , 2018, DOI: 10.4236/ijcm.2018.91004
Abstract: The cochlear implant is a prosthesis that is capable to replace listening capability among patients with sensorineural hearing loss. Many studies suggest a negative relationship among duration of sound deprivation and audiometric gain (by means of speech perception test) after cochlear implantation. We evaluated surgical and audiologic results among post-lingual deafened adults, in different times of sound deprivation, and correlated with social isolation, presence of vertigo or tinnitus, and the speech therapy yield, between pre- and post-operative stages. A retrospective study was conducted on patients with post-lingual hearing loss, aged over 18 years old who underwent cochlear implant surgery in a public hospital from 2004 to 2014. Audiological, socio-demographic questionnaire, and manifestations of vertigo and tinnitus, during pre- and post-operative stages, were compared and correlating to the different periods of sound deprivation. Two groups were studied. The group A was composed of 38 participants (14 male and 24 female) with sound deprivation of less than 10 years; and group B was composed of 17 participants (8 male and 9 female) with sound deprivation longer than 10 years. We found no differences regarding age, sex, duration of sound deprivation, mean pure-tone audiometric results (pre- and post-surgery), and speech perception tests (pre-operatively). After one year of the surgery, we observed a significant difference between both groups, with a better performance to group A. The results of speech perception test, after cochlear implantation in group B, were worse than the results obtained in group A, although these correlations are not determinant whether to perform cochlear implant surgery or not.
Revisional Cochlear Implant Surgeries in Adults  [PDF]
Maria Stella A. Amaral, Henrique F. Pauna, Eduardo T. Massuda, Ana Claudia M. B. Reis, Miguel A. Hyppolito
Advances in Bioscience and Biotechnology (ABB) , 2019, DOI: 10.4236/abb.2019.109020
Abstract: Introduction: Cochlear implant (CI) surgery allows hearing reestablishment among individuals with severe to profound hearing loss. However, only few patients will need a surgical reassessment. Objectives: To verify the incidence of surgical reassessment among adult patients; to verify the reasons that led the second surgery to be performed; to verify the efficacy—and audiological outcomes—of revisional surgery. Method: A longitudinal retrospective cohort study was carried out with the review of medical records, of adult patients, with bilateral severe to profound sensorineural hearing loss who underwent to revisional surgery, from 2004 to 2016 at a CI Center, in Brazil. Results: One hundred fifty-eight CI surgeries were performed among 137 adult patients. Fourteen revisional surgeries were performed among 10 patients: five surgeries were due by displacement of the internal unit; one because of having excessive subcutaneous tissue; one due to non-progression of the electrodes during the initial surgery, one late tympanic membrane perforation, one late facial palsy and, one due to a suture dehiscence in the surgical incision with exposure of the internal unit. Conclusions: The incidence of surgical reassessment among adult CI patients was 8.9%. All implanted patients that underwent a new surgical approach maintained an improved auditory threshold after revisional CI surgery.
Cochlear Implant in a Patient with Arnold-Chiari Syndrome  [PDF]
Maria Stella Arantes do Amaral, Daniela Soares Fonseca, Antonio Carlos dos Santos, Henrique Furlan Pauna, Eduardo T. Massuda, Ana Cláudia Mirandola Barbosa Reis, Miguel Angelo Hyppolito
Case Reports in Clinical Medicine (CRCM) , 2018, DOI: 10.4236/crcm.2018.72014
Abstract: Objective: To verify the efficacy of cochlear implantation in a patient with Arnold-Chiari syndrome. Design: Review of a medical chart from a patient with Arnold-Chiari syndrome that underwent to cochlear implant surgery. Case report: A 6 year-old female, with meningomyelocele and congenital hydrocephalus, deaf in the past 3 years, after meningitis. At that time, she used oral language with adequate speech development. Tone audiometry revealed bilateral profound sensorineural hearing loss. The MRI was compatible with the Arnold-Chiari syndrome. Cochlear implantation was performed on the left ear with MED-EL? Implant (model SONATATi100). Currently, the child is 12 year-old, performs speech therapy three times a week, with good hearing and language development. Conclusion: Despite the presence of Arnold-Chiari syndrome (Chiari type II) with neurological disorders and with ventriculoperitoneal shunt, patient had good hearing results after cochlear implant surgery.
Long Latency Auditory Potential (P300) Outcomes in a Patient with Vestibular Schwannoma after Cochlear Implant Surgery  [PDF]
Maria Stella Arantes do Amaral, Victor Goiris Calderaro, Henrique Furlan Pauna, Eduardo Tanaka Massuda, Ana Cláudia Mirandola Barbosa Reis, MiguelMiguel ?ngelo Hyppolito
Case Reports in Clinical Medicine (CRCM) , 2018, DOI: 10.4236/crcm.2018.75031
Abstract: Background: Neurofibromatosis type 2 (NF2) is a rare syndrome and it is usually presented with bilateral vestibular schwannomas (VS), multiple meningiomas, and other types of tumors associated to peripheral nerves. Hearing loss is one of its leading manifestations, and surgery for removal of the tumor is often required. Cochlear implant (CI) surgery is an option for auditory rehabilitation and long latency auditory potentials (P300) are becoming a very useful tool to assess hearing outcomes. Objective: To verify the presence of P300 waves during auditory and cortical function assessment in a patient submitted to VS removal and CI surgery. Design: Retrospective chart review. Case Report: A 62 years old male patient, presented at the clinic with a bilateral severe to profound hearing loss, worst at the right side. MRI scan revealed bilateral expansive tumor within the internal auditory canal expanding to cerebellopontine angle, suggestive of VS. Tumor was removed at the right side, and CI surgery was indicated for the left ear. P300 tests were performed pre-operatively, at the moment of activation, and 6 months post-operatively. After CI activation, P300 waves appeared, and presented reduced latency and increased amplitude after 6 months of CI use. Conclusion: P300 waves appear to be dependent on the auditory stimulus to be generated, showing that it can be a useful tool to estimate improvement in cortical cognitive function after restoring hearing through CI surgery after VS removal.
Schwannoma de septo nasal: avalia o de massa nasal unilateral Schwannoma of the nasal septum: evaluation of unilateral nasal mass
Henrique Furlan Pauna,Guilherme Machado de Carvalho,Alexandre Caixeta Guimar?es,Rebecca Christina Kathleen Maunsell
Brazilian Journal of Otorhinolaryngology , 2013,
On Local Constraints of D=4 Supergravity in Terms of Dirac Eigenvalues
N. Pauna,I. V. Vancea
Physics , 1998, DOI: 10.1142/S0217732398003296
Abstract: It has been recently shown that in order to have Dirac eigenvalues as observables of Euclidean supergravity, certain constraints should be imposed on the covariant phase space as well as on Dirac eigenspinors. We investigate the relationships among the constraints in the first set and argue that these relationships are not linear. We also derive a set of equations expressing the linear dependency of the constraints in order that the second set of constraints be linearly independent.
Medicina, educa??o e gênero: as diferencia??es sexuais do suicídio nos discursos médicos do século XIX
Lopes, Fábio Henrique;
Educar em Revista , 2007, DOI: 10.1590/S0104-40602007000100016
Abstract: by means of this article, constant and repeated sexual differences in xix century medical discourses are analysed, between suicide committed by men and that one comitted by women. i'm seeking the basis used in order to support such difference and questioning the possibility of thinking about the difference between a male and a female gender of committing suicide, standing out, in this normative process, the role attributed to education and its preventive task.
Maravilha e conhecimento na arte religiosa de Minas colonial
Viana, Fábio Henrique;
Per Musi , 2011, DOI: 10.1590/S1517-75992011000200015
Abstract: baroque religious art built true machines capable of amazing those who approached them. the intent behind such devices was to convert and amaze the faithful, as a kind of "bait" which could attract them, and make them take into account the teachings of the catholic church. in this sense, we seek to identify in religious painting, woodcarving and music of colonial minas gerais (brazil) some artifices employed to provoke wonder and teach the faithful.
As ciências da vida: de Canguilhem a Foucault
Fábio Henrique Lopes
Trabalho, Educa??o e Saúde , 2011,
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