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Search Results: 1 - 10 of 138831 matches for " Hemal K Kanzaria "
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Adie’s Tonic Pupil
Hemal K Kanzaria,Neda Farzan,Zlatan Coralic
Western Journal of Emergency Medicine : Integrating Emergency Care with Population Health , 2012,
Abstract: n/a images in emergency medicine
Malaria treatment-seeking behaviour and recovery from malaria in a highland area of Kenya
Peter O Sumba, S Lindsey Wong, Hemal K Kanzaria, Kelsey A Johnson, Chandy C John
Malaria Journal , 2008, DOI: 10.1186/1475-2875-7-245
Abstract: To assess treatment-seeking behaviour for malaria in these areas, a questionnaire was administered to 117 randomly selected households in the highland area of Kipsamoite, Kenya. Self-reported episodes of malaria occurred in 100 adults and 66 children.The most frequent initial sources of treatment for malaria in adults and children were medical facilities (66.0% and 66.7%) and local shops (19.0% and 30.3%). Adults and children who initially visited a medical facility for treatment were significantly more likely to recover and require no further treatment than those who initially went to a local shop (adults, 84.9% v. 36.8%, P < 0.0001, and children, 79.6% v. 40.0%, P = 0.002, respectively). Individuals who attended medical facilities recalled receiving anti-malarial medication significantly more frequently than those who visited shops (adults, 100% vs. 29.4%, and children, 100% v. 5.0%, respectively, both P < 0.0001).A significant proportion of this highland population chooses local shops for initial malaria treatment and receives inappropriate medication at these localshops, reslting in delay of effective treatment. Shopkeeper education has the potential to be a component of prevention or containment strategies for malaria epidemics in highland areas.Malaria is a leading cause of death in children under the age of five years in sub-Saharan Africa [1]. The Roll-Back Malaria (RBM) initiative is working to improve prevention efforts in affected countries, through insecticide-treated nets (ITNs), indoor residual spraying (IRS) of pesticides, and intermittent preventive treatment (IPT) for pregnant women [2]. RBM also focuses on intervention efforts via effective anti-malarial regimens like artemesinin-based combination therapy (ACT), pre-empting epidemics in epidemic-prone areas, and improving home management of the disease. Rapid, effective treatment response with ACT is currently the most effective treatment option in sub-Saharan Africa, considering the current state
Cardiac Tamponade
Jennifer G. Wilson,Sara M. Epstein,Ralph Wang,Hemal K. Kanzaria
Western Journal of Emergency Medicine : Integrating Emergency Care with Population Health , 2013,
Abstract: None Images in Emergency Medicine
Role of Robot-Assisted Pelvic Surgery
Iqbal Singh,Ashok K. Hemal
The Scientific World Journal , 2009, DOI: 10.1100/tsw.2009.54
Design, Synthesis and Biological Evaluation of Novel Antitubercular Agents by Combining Pyrazoline and Benzoxazole Pharmacophores  [PDF]
Hemal M. Soni, Popatbhai K. Patel, Mahesh T. Chhabria, Ashish K. Patel, Dharmraj N. Rana, Pathik S. Brahmkshatriya
International Journal of Organic Chemistry (IJOC) , 2016, DOI: 10.4236/ijoc.2016.63017
Abstract: Various recent reports on Tuberculosis have alarmed an increase in the patient class and subsequent death rates across the globe. Over and above the spread of more dangerous and fatal forms of tuberculosis like MDR-TB i.e. multiple-drug resistance tuberculosis, XDR-TB i.e. extensively-drug resistance tuberculosis & TDR-TB i.e. total-drug resistance tuberculosis has forwarded an urgent need to discover novel antitubercular agents. The current work is aimed at combining two previously well-known pharmacophores (pyrazoline and benzoxazole nucleus) in order to design and synthesize a series of novel benzoxazole-based pyrazoline derivatives. The synthesized target compounds were structurally confirmed by LCMS, 1H-NMR and 13C-NMR analysis. The target compounds were In vitro evaluated against M. tuberculosis H37Rv strain, multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) strains. The In vitro screening results depicted that majority of the target compounds displayed potent activity with MIC in a range of ~0.8 to 6.25 μg/mL. Many compounds were found to be more potent than isoniazid against MDR-TB with MIC value 3.12 μg/mL and XDR-TB with MIC value 12.5 μg/mL. Cytotoxicity assay of these active compounds on VERO cell lines also displayed good selectivity index.
2D-QSAR Study of a Series of Pyrazoline-Based Anti-Tubercular Agents Using Genetic Function Approximation  [PDF]
Hemal M. Soni, Popatbhai K. Patel, Mahesh T. Chhabria, Dharmraj N. Rana, Bhushan M. Mahajan, Pathik S. Brahmkshatriya
Computational Chemistry (CC) , 2015, DOI: 10.4236/cc.2015.34006
Abstract: A series of pyrazoline-based new heterocycles have recently been synthesized from our group where some of the compounds display potent anti-tubercular activity against Mycobacterium tuberculosis H37Rv. In order to further explore the potency of the compounds, quantitative structure activity relationship study is carried out using genetic function approximation. Statistically significant (r2 = 0.85) and predictive (r2pred=0.89 and r2m=0.74)?QSAR models are developed. It is evident from the QSAR study that majority of the anti-tubercular activity is found to be driven by lipophilicity. Also, molecular solubility, Jurs and shadow descriptors influence the biological activity significantly. Also, positive contribution of molecular shadow descriptors suggests that molecules with bulkier substituents are more likely to enhance anti-tubercular activity. Since the developed QSAR models are found to be statistically significant and predictive, they potentially can be applied for predicting anti-tubercular activity of new molecules for prioritization of molecules for synthesis.
Efficient Routing Using Temporal Distance in Intermittently Connected Mobile Ad-hoc Networks  [PDF]
Hemal Shah, Yogeshwar Kosta, Vikrant Patel
Communications and Network (CN) , 2013, DOI: 10.4236/cn.2013.53033

The analysis of real social, biological and technological networks has attracted a lot of attention as technological advances have given us a wealth of empirical data. For, analysis and investigation time varying graphs are used to understand the relationship, contact duration, repeated occurrence of contact. It is under exploring in intermittently connected networks. Now, by extending the same concept in intermittent networks, the efficiency of the routing protocol can be improved. This paper discusses about the temporal characterizing algorithm. Such characterization can help in accurately understanding dynamic behaviors and taking appropriate routing decisions. Therefore, the present research provokes exploring different possibilities of utilizing the same time varying network analyses and designing an Adaptive Routing protocol using temporal distance metric. The adaptive routing protocol is implemented using ONE simulator and is compared with the Epidemic and PropHET for delivery ratio, overhead and the number of dropped messages. The result reveals that Adaptive routing performs better than Epidemic and PropHET for real and synthetic datasets.

Pure robotic retrocaval ureter repair
Hemal, Ashok k.;Rao, Ranjit;Sharma, Sachit;Clement, Rhys G. E.;
International braz j urol , 2008, DOI: 10.1590/S1677-55382008000600008
Abstract: purpose: to demonstrate the feasibility of pure robotic retrocaval ureter repair. materials and methods: a 33 year old female presented with right loin pain and obstruction on intravenous urography with the classical "fish-hook" appearance. she was counseled on the various methods of repair and elected to have a robot assisted repair. the following steps are performed during a pure robotic retrocaval ureter repair. the patient is placed in a modified flank position, pneumoperitoneum created and ports inserted. the colon is mobilized to expose the retroperitoneal structures: inferior vena cava, right gonadal vein, right ureter, and duodenum. the renal pelvis and ureter are mobilized and the renal pelvis transected. the ureter is transposed anterior to the inferior vena cava and a pyelopyelostomy is performed over a jj stent. results: this patient was discharged on postoperative day 3. the catheter and drain tube were removed on day 1. her jj stent was removed at 6 weeks postoperatively. the postoperative intravenous urography at 3 months confirmed normal drainage of contrast medium. conclusion: pure robotic retrocaval ureter is a feasible procedure; however, there does not appear to be any great advantage over pure laparoscopy, apart from the ergonomic ease for the surgeon as well the simpler intracorporeal suturing.
Robot-assisted urologic surgery in 2010 - Advancements and future outlook
Babbar Paurush,Hemal Ashok
Urology Annals , 2011,
Abstract: Robotic surgery is a cutting edge and minimally invasive procedure, which has generated a great deal of excitement in the urologic community. While there has been much advancement in this emerging technology, it is safe to say that robotic urologic surgery holds tremendous potential for progress in the near future. Hence, it is paramount that urologists stay up-to-date regarding new developments in the realm of robotics with respect to novel applications, limitations and opportunities for incorporation into their practice. Robot-assisted surgery provides an enhanced 3D view, increased magnification of the surgical field, better manual dexterity, relatively bloodless field, elimination of surgeon′s tremor, reduction in a surgeon′s fatigue and mitigation of scattered light. All these factors translate into greater precision of surgical dissection, which is imperative in providing better intraoperative and postoperative outcomes. Pioneering work assessing the feasibility of robotic surgery in urology began in the early 2000′s with robot-assisted radical prostatectomy and has since expanded to procedures such as robot-assisted radical cystectomy, robot-assisted partial nephrectomy, robot-assisted nephroureterectomy and robot-assisted pyeloplasty. A MEDLINE search was used to identify recent articles (within the last two years) and publications of specific importance, which highlighted the recent developments and future direction of robotics. This review will use the aforementioned urologic surgeries as vehicles to evaluate the current status and future role of robotics in the advancement of the field of urology.
Laparoscopy, robot, telesurgery and urology: future perspective.
Hemal A,Menon M
Journal of Postgraduate Medicine , 2002,
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