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Search Results: 1 - 10 of 32637 matches for " Helio;Oliveira "
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Forma o interdisciplinar e sustentabilidade em cursos de administra o: desafios e perspectivas.
Jacques Demajorovic,Helio Cesar Oliveira Da Silva
Revista de Administra??o Mackenzie , 2012,
Abstract: A incorpora o da educa o para a sustentabilidade nos currículos formais, como instrumento que estimule os indivíduos à reflex o e à a o acerca dos desafios da sustentabilidade, tem se mostrado uma tarefa bastante complexa nos mais diferentes campos de conhecimento. Isso se evidencia, particularmente, quando se pensa nas estruturas dos currículos tradicionais dos cursos de administra o. Este artigo tem como objetivo identificar desafios para a integra o da sustentabilidade em cursos de administra o e como esse conhecimento influencia na trajetória profissional de egressos de um curso de Administra o com Linha de Forma o Específica em Gest o Ambiental. A metodologia empregada incluiu o envio de um questionário para as duas primeiras turmas de formandos do curso e a realiza o de um grupo focal para aprofundamento dos resultados levantados na primeira fase. Os resultados mostram que os alunos reconhecem as práticas interdisciplinares como elementos centrais em seu processo de forma o, considerando que elas contribuem para o desenvolvimento de competências profissionais significativas para um administrador com responsabilidade socioambiental. As competências mais mencionadas pelos egressos foram trabalho em equipe e negocia o com atores sociais. Entretanto, a pesquisa indica um grande desafio para esses egressos: o mercado continua a entender os desafios da sustentabilidade como um problema de caráter prioritariamente tecnológico, em detrimento das competências em gest o, levando a uma valoriza o de engenheiros e tecnólogos para atuar no campo da sustentabilidade. Nesse contexto, o desafio mostra-se muito maior do que apenas incorporar conteúdos de sustentabilidade na forma o de futuros administradores – requer também entender como administradores comprometidos com a quest o socioambiental podem se legitimar para viabilizar sua efetiva inser o nas organiza es.
BUYER-SELLER RELATIONSHIP MANAGEMENT IN STRUCTURED CONTRACTS ENVIRONMENTS: A CASE STUDY IN A MULTINATIONAL FIRM GESTIóN DE RELACIONAMIENTO COMPRADOR-PROVEEDOR EN AMBIENTES CON CONTRATOS ESTRUCTURADOS: EL CASO DE UNA GRAN MULTINACIONAL GEST O DO RELACIONAMENTO COMPRADOR-FORNECEDOR EM AMBIENTES COM CONTRATOS ESTRUTURADOS: O CASO DE UMA GRANDE MULTINACIONAL
Felipe Pagiola de Oliveira,Helio Zanquetto Filho
Rege : Revista de Gest?o , 2013,
Abstract: The article objective is to analyze the relationships between buyers and sellers in organizational environments where structured contracts are used, more specifically when it is used to ruled relational aspects in these relationships. The focus of this analysis was a big multinational company and its suppliers. Five relationships were selected, and three categories were chosen by which was structured the interviews script, to be applied to eleven managers. The results had shown that there is not a relational contract to treat all the relationship management issues, but verified the existence of informal rules and norms agreed between the parts that provide attendance to this finality. El objetivo de la presente investigación es analizar las relaciones entre contratante y contratados en ambientes con utilización de contratos estructurados, más específicamente el empleo de esos contratos para tratar de los aspectos relacionales de esas relaciones. Así que, el foco principal de la presente investigación son las relaciones entre una gran multinacional y sus proveedores de productos y servicios. Como estrategia de investigación, fue realizada, primeramente, un sondeo en 94 contratos establecidos por la contratante. A partir de ese levantamiento, teniendo como referencia seis parámetros identificados en la revisión de la literatura, fue realizada la elección de los cinco casos (contratos) a ser estudiados. Esos mismos parámetros fueron utilizados para la definición del guión de la entrevista. Una vez definidos los casos, fueron seleccionados once gestores (sujetos de la investigación) de la contratante y de los contratados, para la realización de las entrevistas. Como conclusión, se observa que en contratos con suministro de poca tecnología existe mayor dependencia de la contratada, mas esa dependencia diminuye a medida que se incorpora más tecnología en el suministro de productos y servicios. En relación a la gobernabilidad de las relaciones, no existe formalización de los elementos relacionales, lo que puede crear problemas relativos al uso del oportunismo por parte de los contratados. El último aspecto remite a los mecanismos isomorfos, una vez que contratos distintos entre las mismas organizaciones son vistos por las partes como únicos, por estar sujetos a las mismas condiciones y presiones y por tener gestiones similares. O objetivo da presente pesquisa é analisar relacionamentos entre contratante e contratados em ambientes que utilizam contratos estruturados, mais especificamente o emprego desses contratos para tratar dos aspectos relacionais desses
Resposta humoral, recupera o bacteriana e les es histológicas em camundongos geneticamente selecionados para bons e maus produtores de anticorpos e Balb/c, frente à infec o por Leptospira interrogans sorovar icterohaemorrhagiae
Marinho Márcia,Langoni Helio,Oliveira Silvio Luis,Carreira Rodrigo
Pesquisa Veterinária Brasileira , 2003,
Abstract: O presente trabalho teve por finalidade associar a cinética da resposta humoral à recupera o de leptospiras viáveis e à intensidade das les es teciduais em camundongos geneticamente selecionados para bons (High) e maus (Low) produtores de anticorpos (sele o IV-A), além de camundongos outbreed, Balb/c, inoculados com amostra patogênica de Leptospira interrogans sorovar icterohaemorrhagiae. As linhagens High e Low (sele o IV-A) apresentam modifica es em alguns compartimentos da resposta imune, principalmente em rela o à atividade macrofágica, representando fenótipos extremos encontrados em popula es naturais heterogêneas. Os camundongos foram sacrificados em oito momentos após a infec o. A análise dos resultados revelou que a partir do 7o dia após a infec o, os camundongos da linhagem High apresentaram eleva o nos títulos de anticorpos estatisticamente significantes quando comparados aos camundongos da linhagem Low, mantendo assim o efeito multiespecífico. Os camundongos Balb/c apresentaram resultados intermediários entre as duas linhagens. A produ o de anticorpos colaborou como fator limitante à infec o, pois quando obteve-se maior recupera o de leptospiras, na fase inicial da infec o, os títulos de anticorpos encontravam-se em eleva o. As les es observadas nos órg os de camundongos infectados consistiram basicamente nos mesmos processos inflamatórios e degenerativos, que n o se alteraram, variando apenas o grau de comprometimento tecidual, de acordo com a linhagem. A linhagem high apresentou les es mais extensas que as apresentadas pelas linhagens low e Balb/c, sendo que nesta última as les es foram moderadas. De forma geral a linhagem High e Balb/c apresentaram um perfil de resposta Th2, com o maior índice de produ o de anticorpos e gravidade das les es, enquanto a linhagem Low apresentou um perfil de resposta Th1.
A fast algorithm for computing the Hartley/ Fourier spectrum
OLIVEIRA HELIO M. DE,SOUZA RICARDO M. C. DE
Anais da Academia Brasileira de Ciências , 2001,
Abstract:
Extended Dynamic Generalized Linear Models: the two-parameter exponential family
Mariana Albi de Oliveira Souza,Helio dos Santos Migon
Statistics , 2015,
Abstract: We develop a Bayesian framework for estimation and prediction of dynamic models for observations from the two-parameter exponential family. Different link functions are introduced to model both the mean and the precision in the exponential family allowing the introduction of covariates and time series components. We explore conjugacy and analytical approximations under the class of partial specified models to keep the computation fast. The algorithm of West, Harrison and Migon (1985) is extended to cope with the two-parameter exponential family models. The methodological novelties are illustrated with two applications to real data. The first, considers unemployment rates in Brazil and the second some macroeconomic variables for the United Kingdom.
Initial Analysis of Lipid Metabolomic Profile Reveals Differential Expression Features in Myeloid Malignancies  [PDF]
Adriana Ramos de Oliveira, Ismael Dale Cotrim Guerreiro Da Silva, Edson G. Lo Turco, Helio Alves Martins Júnior, Maria de Lourdes L. Ferrari Chauffaille Chauffaille
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.615138
Abstract: The purpose of this preliminary study was to determine the comparative lipid profile of blood plasma samples of healthy individuals and patients with Myeloproliferative Neoplasms. Methods: Untargeted Shotgun MS/MS Analysis was performed to evaluate plasma samples from 153 participants, being 90 of the Control Group, 43 Myeloproliferative Neoplasms (MPN), 11 Myelodysplastic Syndromes (MDS) and 9 Acute Myeloid Leukemias (AML). Lipids were extracted from plasma using the Bligh-Dyer protocol. Data were acquired using the AB-Sciex Analyst TF, processed using the AB-Sciex LipidViewTM and the web-based analytical pipeline MetaboAnalyst 2.0 (www.metaboanalyst.ca). Results: Untargeted analysis identified in negative and positive-modes a total of 658 features at 2 ppm resolution. PCA and PLS-DA analysis revealed clear discrimination among groups, in particular for AML patients. Main lipid groups differentially expressed were: Monoacylglycerols (MAG), Glucosylceramide E (GlcdE), Ethyl Esters (EE), Lysophosphatidic acid (LPA), Sulfoquinovosil diacylglycerols (SQDG), Monoglycerols (MG), Methyl Ethanolamines (ME), Lysophosphatidylcholines (LPC), Dimethyl Phosfatidyletanolamines (DMPE), Monometylphosphatidiletanolamines (MMPE), Ceramide-1-phosphate (CerP), Glicerophosphoglycerols (GP), Lysomonomethyl-Phosphatidylethanolamines (LMMPE), Phosphatidic Acids (PA), Ergosterols (ERG), Glycerophosphoserine (PS), Diacylglycerols (DAG), Hexocylceramides (HexCer) and Lanosterol (Lan). ROC Curve Analysis revealed Total LMMPE as the strongest discriminating marker between Controls from Patients. In addition, these lipids were also able to differentiate MDS and AML from NPM. Conclusions: The Myeloproliferative Neoplasms from the point of view
Clinical Assessment of the Use of Propinox Hydrochloride and Scopolamine Hydrochloride in the Treatment of Abdominal Colic: A Retrospective, Comparative Study  [PDF]
Helio Rzetelna, Carlos Frederico Porto Alegre Rosa, Mario Kirzner, Lucas Pereira Jorge de Medeiros, Camila Melo, Marcia Gon?alves Ribeiro, Lisa Oliveira, José Galv?o Alves, Mauro Geller
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.77052
Abstract: Objectives: The purpose of this study was to evaluate and compare the use of propinox hydrochloride and scopolamine hydrochloride in patients presenting abdominal colic (abdominal pain), in terms of treatment efficacy and tolerability. Material & Methods: This was an analytical, retrospective, comparative study based on hospital records of outpatients treated at Serviço de Clínica Médica do Hospital das Clínicas Costantino Otaviano (HCTCO) and at Santa Casa de Misericórdia do Rio de Janeiro, from 1988-1998. Subjects were divided into two groups: patients from Group 1 were treated with propinox hydrochloride, while patients from Group 2 were treated with scopolamine hydrochloride. Statistical analysis was performed using GraphPad Prism version 5.0. For comparison of categorical variables, we used the chi-squared or Fisher’s test, while continuous variables were analyzed using ANOVA or the Student’s T test. Results: A total of 1042 subjects were included, of which 525 were allocated to Group 1 and 517 to Group 2. Mean treatment duration was 9.166 days (±4.208) in Group 1 and 8.795 days (±5.052) in Group 2, with no statistically significant difference in treatment duration between the two groups (p = 0.198). All subjects in Group 1 were treated with propinox 10 mg (2 coated tablets, three times per day) while all subjects in Group 2 were treated with scopolamine hydrochloride 10 mg (2 coated tablets, three times per day). There were no statistically significant between-group differences in weight, BMI, heart rate, and respiratory rate at pre- and post-treatment; with the exception of higher post-treatment systolic blood pressure in Group 1, blood pressure measures also remained homogenous. Adverse events were reported among both treatment groups with no significant between-group difference in incidence (p = 0566). At pretreatment, pain intensity was more severe in Group 1 (p = 0.0257), while at post-treatment, there was no statistically significant difference between the two treatment groups (p = 0.895). There was a statistically significant improvement in pain intensity within both treatment groups (χ2 = 631.4; df = 3; p < 0.0001 for Group 1 and χ2 = 554.3; df = 3; p < 0.0001 for Group 2). Conclusion: The results obtained in this study indicate a therapeutic equivalence between propinox hydrochloride and scopolamine hydrochloride. Both treatments demonstrated good efficacy and tolerability in the treatment of abdominal colic pain, in the population evaluated.
Ritmo circadiano e doen?a vascular encefálica: um estudo de correla??o com fatores de risco
Oliveira, Helio Araújo;Moreira, álvaro José Porto;Oliveira, Arthur Maynart Pereira;
Arquivos de Neuro-Psiquiatria , 2004, DOI: 10.1590/S0004-282X2004000200018
Abstract: the human biological mechanisms show a predictable clinical variability in time, which has allowed a deeper reevaluation of present-day medical practices, regarding the circadian rhythm (cr) and the mechanisms that produce the supported variations in all biological levels. we have made a study aiming to relate the cr and onset of the neurological clinic situation due to the encephalic vascular lesion, correlating with modifying risk factors. fifty three patients were studied, 50,94% female (n=27) and 49,50% male (n=26), at average age 66.4 years old. four intervals of six hours each (0-6; 6-12; 12-18; 18-24) were used to analyze the frequency of the ictus and the incidence in each interval. we found an incidence of 6(11.32%) patients in the 0-6 hs interval; 21 (39.62%) patients in the 6-12 hs interval; 10(18.86%) patients in the 12-18 hs interval; 16 (30.18%) patients in the 18-24 interval. a correlative study with the risk factors has shown that arterial hypertension [(81.25%)] and smoking habit [ (56.25)] were predominant during the 18-24 hs interval, while sedentary [11(52.38%)] stress [11(52.38%)] diabetes [(47.61%)] hyperlipidemia [8 (38.09%)] and alcoholism [8 (38.09%] were predominant during the 6-12 hs interval; and cardiac diseases in the 12-18hs interval.
Ritmo circadiano e doen a vascular encefálica: um estudo de correla o com fatores de risco
Oliveira Helio Araújo,Moreira álvaro José Porto,Oliveira Arthur Maynart Pereira
Arquivos de Neuro-Psiquiatria , 2004,
Abstract: Os mecanismos biológicos humanos exibem variabilidade clínica previsível no tempo, o que tem permitido reavalia o das práticas médicas atuais, do estudo mais aprofundado do ritmo circadiano (RC) e dos mecanismos que geram as oscila es sustentadas em todos os níveis biológicos. Fizemos um estudo procurando relacionar o RC e o momento do aparecimento do quadro clínico neurológico decorrente da les o vascular do encéfalo com os fatores de risco modificáveis identificados no momento da interna o. Foram estudados 53 pacientes, sendo 50,94% (n =27) do sexo feminino e 49,50%(n =26) do masculino, com média de idade de 66,4 anos. Quatro intervalos de 6 horas (0-6; 6-12; 12-18; 18-24) foram usados para análise da freqüência do ictus e da incidência em cada intervalo. Os resultados mostraram 6 (11,32%) pacientes no intervalo 0-6 hs; 21 (39,62%) no intervalo 6-12 hs; 10 (18,86%) no intervalo 12-18 hs; 16 (30,18%) no intervalo 18-24 hs. Estudo de correla o com os fatores de risco, baseado nos dados clínicos no momento da interna o, mostrou que a hipertens o arterial [(81,25%)] e o tabagismo[ (56,25%)] predominaram no intervalo 18-24 hs, enquanto o sedentarismo[11; (52,38%)] o estresse[11 (52,38%)] o diabetes [(47,61%)] a hiperlipidemia [8 (38,09%)] e o alcoolismo[8 (38,09%)] predominaram no intervalo 6-12 hs; as cardiopatias [(50,00%)] predominaram no intervalo de 12-18 hs.
Myocardial performance in conscious streptozotocin diabetic rats
Giulianna R Borges, Mauro de Oliveira, Helio C Salgado, Rubens Fazan
Cardiovascular Diabetology , 2006, DOI: 10.1186/1475-2840-5-26
Abstract: Cardiac contractility and relaxation were evaluated by means of maximum positive (+dP/dtmax) and negative (-dP/dtmax) values of first derivative of left ventricular pressure over time. In addition, it was examined the myocardial response to stress caused by two dosages (1 and 15 μg/kg) of dobutamine. One-way analysis of variance (ANOVA) was used to compare differences among groups, and two-way ANOVA for repeated measure, followed by Tukey post hoc test, to compare the responses to dobutamine. Differences were considered significant if P < 0.05.Basal mean arterial pressure, heart rate, +dP/dtmax and -dP/dtmax were found decreased in STZ-diabetic rats, but unaltered in control rats treated with vehicle and STZ-diabetic rats treated with insulin. Therefore, insulin prevented the hemodynamic and myocardial function alterations observed in STZ-diabetic rats. Lower dosage of dobutamine increased heart rate, +dP/dtmax and -dP/dtmax only in STZ-diabetic rats, while the higher dosage promoted greater, but similar, responses in the three groups. In conclusion, the results indicate that myocardial function was remarkably attenuated in conscious STZ-diabetic rats. In addition, the lower dosage of dobutamine uncovered a greater responsiveness of the myocardium of STZ-diabetic rats. Insulin preserved myocardial function and the integrity of the response to dobutamine of STZ-diabetic rats.The present study provides new data from conscious rats showing that the cardiomyopathy of this pathophysiological condition was expressed by low indices of contractility and relaxation. In addition, it was also demonstrated that these pathophysiological features were prevented by the treatment with insulin.Besides increased incidence of autonomic neuropathy and coronary artery disease, diabetes has been considered an independent risk for myocardial dysfunction [1,2].It is well documented in experimental diabetes that both left ventricular diastolic [3,4] and systolic dysfunction [5,6] are attrib
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