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Search Results: 1 - 10 of 208891 matches for " Helene L. Soberg "
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Health Outcome after Major Trauma: What Are We Measuring?
Karen Hoffman, Elaine Cole, E. Diane Playford, Eva Grill, Helene L. Soberg, Karim Brohi
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0103082
Abstract: Importance Trauma is a global disease and is among the leading causes of disability in the world. The importance of outcome beyond trauma survival has been recognised over the last decade. Despite this there is no internationally agreed approach for assessment of health outcome and rehabilitation of trauma patients. Objective To systematically examine to what extent outcomes measures evaluate health outcomes in patients with major trauma. Data Sources MEDLINE, EMBASE, and CINAHL (from 2006–2012) were searched for studies evaluating health outcome after traumatic injuries. Study selection and data extraction Studies of adult patients with injuries involving at least two body areas or organ systems were included. Information on study design, outcome measures used, sample size and outcomes were extracted. The World Health Organisation International Classification of Function, Disability and Health (ICF) were used to evaluate to what extent outcome measures captured health impacts. Results 34 studies from 755 studies were included in the review. 38 outcome measures were identified. 21 outcome measures were used only once and only five were used in three or more studies. Only 6% of all possible health impacts were captured. Concepts related to activity and participation were the most represented but still only captured 12% of all possible concepts in this domain. Measures performed very poorly in capturing concepts related to body function (5%), functional activities (11%) and environmental factors (2%). Conclusion Outcome measures used in major trauma capture only a small proportion of health impacts. There is no inclusive classification for measuring disability or health outcome following trauma. The ICF may provide a useful framework for the development of a comprehensive health outcome measure for trauma care.
Estimation of means in graphical Gaussian models with symmetries
Helene Gehrmann,Steffen L. Lauritzen
Statistics , 2011, DOI: 10.1214/12-AOS991
Abstract: We study the problem of estimability of means in undirected graphical Gaussian models with symmetry restrictions represented by a colored graph. Following on from previous studies, we partition the variables into sets of vertices whose corresponding means are restricted to being identical. We find a necessary and sufficient condition on the partition to ensure equality between the maximum likelihood and least-squares estimators of the mean.
Management of chronic knee pain: A survey of patient preferences and treatment received
Helene L Mitchell, Michael V Hurley
BMC Musculoskeletal Disorders , 2008, DOI: 10.1186/1471-2474-9-123
Abstract: At baseline assessment of a clinical trial of rehabilitation for chronic knee pain, 415 participants were asked about their i) previous management, ii) preferred treatment, if any, iii) whether they would undergo knee surgery and iv) reasons for their preferences.Previous management – Medication was the most common treatment, followed by physiotherapy, 39 participants had received no treatment. Preferences – 166 patients expressed no treatment preference. Of those who expressed a preference the most popular option was physiotherapy, whilst not having surgery was the third most frequent response. The most common reason for preferring physiotherapy and not wanting surgery was prior experience.Willingness to accept surgery – 390 participants were not waiting for knee replacement surgery, and overall 81% would not accept surgery if offered, usually because pain was not perceived to be severe enough to warrant surgery.Most chronic knee pain is managed with medication despite concerns about safety, efficacy and cost, management guidelines recommendations and people's management preferences. Previous experience and perceptions of need were major determinants of people's preferences, but many people were unaware of management options. Appreciating patient preferences and provision of more information about management options are important in facilitating informed patient/clinician discussion and agreement.Current Controlled Trials, ISRCTN 94658828Disabling chronic knee pain is very common [1,2]. Although evidence-based guidelines recommend exercise, education, and medication [3], management of chronic knee pain usually involves palliative medication, in spite of its potential risks and costs [4,5]. Fewer people are referred to physiotherapy [6] and only people with severe, disabling pain are referred for total knee replacement (TKR) surgery [7].There have been calls for management decision-making to shift from doctor-determined to one which includes greater patient involvem
Acceptance of Nordic snack bars in children aged 8–11 years
Anna Holmer,Helene Hausner,Helene C. Reinbach,Wender L. P. Bredie
Food & Nutrition Research , 2012, DOI: 10.3402/fnr.v56i0.10484
Abstract: Background: A health promoting diet is suggested to be tailored to regional circumstances to preserve the cultural diversity in eating habits, as well as contribute to more environmentally friendly eating. It may influence consumer acceptance, however, if the components of the diet differs considerably from their habitual food. Objective: This study aimed to investigate whether snack bars composed of Nordic ingredients were accepted by 8–11 year-old Danish (n=134) and Swedish (n=109) children.Design: A seven-point hedonic scale was used to measure the children's acceptance of five snack bars that varied in their composition of whole grains, berries and nuts. A preference rank ordering of the five bars was also performed. Results: The results showed that samples that were rated highest in liking and were most preferred in both countries were a kamut/pumpkin bar and an oat/cranberry bar. The sample with the lowest rating that was also least preferred was a pumpernickel/sea buckthorn bar. Flavour was the most important determinant of overall liking followed by texture, odour and appearance. Conclusions: Children's acceptances and preferences were highly influenced by the sensory characteristics of the bars, mainly flavour. In agreement with earlier studies, the novel food ingredients seemed to influence children's preferences. The Nordic snack bars may have a potential to be a snack option for Danish and Swedish school children, but repeated exposures to the products are recommended to increase children's acceptance.
A gene frequency model for QTL mapping using Bayesian inference
Wei He, Rohan L Fernando, Jack CM Dekkers, Helene Gilbert
Genetics Selection Evolution , 2010, DOI: 10.1186/1297-9686-42-21
Abstract: To simplify the analysis, data from unrelated individuals in a purebred population were simulated, where only LD information contributes to map the QTL. LD was simulated in a chromosomal segment of 1 cM with one QTL by random mating in a population of size 500 for 1000 generations and in a population of size 100 for 50 generations. The comparison was studied under a range of conditions, which included SNP density of 0.1, 0.05 or 0.02 cM, sample size of 500 or 1000, and phenotypic variance explained by QTL of 2 or 5%. Both 1 and 2-SNP models were considered. Power to detect the QTL for the BGF, ranged from 0.4 to 0.99, and close or equal to the power of the regression using least squares (LSR). Precision to map QTL position of BGF, quantified by the mean absolute error, ranged from 0.11 to 0.21 cM for BGF, and was better than the precision of LSR, which ranged from 0.12 to 0.25 cM.In conclusion given a high SNP density, the gene frequency model can be used to map QTL with considerable accuracy even within a 1 cM region.Molecular information is currently being used for mapping quantitative trait loci (QTL) and for genetic evaluation. This information usually consists of molecular genotypes at polymorphic loci. These loci can be broadly classified into two types: I) those that have a direct effect on the trait, and II) those that do not have a direct effect on the trait but are linked to a trait locus (markers). Loci of type II can be further classified into two types: IIa) loci that are in linkage disequilibrium with the trait locus across the population (LD markers), and IIb) loci that are in linkage equilibrium with the trait locus (LE markers) [1]. In outbred populations, until recently, marker analyses were primarily based on LE markers [2-6]. LE markers do not provide information to model the mean at linked QTL, but they do provide information to model covariances at the linked QTL. These covariances can be written in terms of the conditional IBD probabilities at
A reprodu??o social da hanseníase: um estudo do perfil de doentes com hanseníase no Município de S?o Paulo
Helene, Lúcia Maria Fraz?o;Salum, Maria Josefina Leuba;
Cadernos de Saúde Pública , 2002, DOI: 10.1590/S0102-311X2002000100011
Abstract: this study discusses the relationship between work and living conditions among leprosy patients enrolled in the s?o paulo municipal public health system in 1996. social patterns were studied based on the theory of social determination of the health-disease process. the main purpose of the study was to emphasize evidence of the disease determination network, seeking new knowledge to improve public policies on leprosy. data were gathered from a sample of leprosy patients registered in the city's public health system. although patients' families are characterized by a common social thread, different work/life possibilities allow for a classification of patients into three social groups. the majority belong to groups that are marginalized from social production, living in areas where social exclusion is more extreme, on the outskirts of the city. if the trends in this study persist, incident leprosy cases will result from the social exclusion of migrants from brazil's southeast and northeast. the study also discusses the position of young people and female patients in the determination network of this infectious disease in the city of s?o paulo.
Identifica??o de alguns problemas psicossociais em portadores de hanseníase utilizando para a análise os recursos da informática
Helene, Lúcia Maria Fraz?o;Rocha, Marly Theoto;
Revista da Escola de Enfermagem da USP , 1998, DOI: 10.1590/S0080-62341998000300003
Abstract: the purpose of this study was to identify leprosy patients' psychosocial problems experienced after they were informed about their diagnosis. we foccused attention upon concerns and behavioral changes related to their families, friends, jobs and to themselves. data were obtained by a two opened questions interview and they were analysed with the aid of artificial intelligence techniques. these inteligence tools were used to discover the most frequent words, phrases and concepts existing in the interview reports. the results showed that after being informed about their diagnosis, the majority of the patients referred some concerns and behavioral changes related to their families, friends, jobs and to themselves. the main concerns of the population were related to the disease (transmission, the treatment extension, the possibility of hospitalization, the uncertainty about the cure). these facts induced some of the patients to avoid telling people about the disease they have.
Improvement of physical and chemical properties of concrete with brazilian silica rice husk (SRH)
Silva,Fernanda Giannotti da; Liborio,Jefferson B. L.; Helene,Paulo;
Revista ingeniería de construcción , 2008, DOI: 10.4067/S0718-50732008000100002
Abstract: the use of industrial and agricultural waste substitutions for portland cement has greatly contributed to sustainable development practices. the increase in cement demand will be met by the use of supplementary cementing materials, in order to minimize the clinker consumption. in this study, the effects of silica extracted from rice husk (srh) as a partial replacement of cement in concretes with low water/binder are reported. the properties investigated include compressive strength, splitting tensile strength, water absorption by immersion, water absorption by capillarity and resistance to chloride ion penetration. the research indicates that srh is an effective mineral addition for designing durable concrete presenting an optimal performance when the replacement ratio of portland cement is around 10%
Improvement of physical and chemical properties of concrete with brazilian silica rice husk (SRH) La mejora de propiedades físicas y químicas de hormigón con silice de cáscara de arroz (SRH) brasile a
Fernanda Giannotti da Silva,Jefferson B. L. Liborio,Paulo Helene
Revista ingeniería de construcción , 2008,
Abstract: The use of industrial and agricultural waste substitutions for Portland cement has greatly contributed to sustainable development practices. The increase in cement demand will be met by the use of supplementary cementing materials, in order to minimize the clinker consumption. In this study, the effects of silica extracted from rice husk (SRH) as a partial replacement of cement in concretes with low water/binder are reported. The properties investigated include compressive strength, splitting tensile strength, water absorption by immersion, water absorption by capillarity and resistance to chloride ion penetration. The research indicates that SRH is an effective mineral addition for designing durable concrete presenting an optimal performance when the replacement ratio of Portland cement is around 10% El uso de desechos industriales y agrícolas como segmento en la producción de cemento Portland ha contribuido de manera importante en la práctica de desarrollo sustentable. El aumento en la demanda de cemento coincide con el uso de materiales aglomerantes suplementarios para minimizar el consumo de clinker. En este estudio, se informan los efectos de la sustitución parcial de cemento Portland por sílice extraído de la cascara de arroz (SRH) en hormigones con baja relación agua/materiales cementicios. Las propiedades investigadas incluyen resistencia a la compresión, resistencia a la tracción, absorción de agua por inmersión, absorción de agua por capilaridad y resistencia a la penetración de iones de cloruro. La investigación indica que SRH es una adición mineral eficaz para el dise o de hormigones durables que presenta una actuación óptima cuando la proporción del reemplazo de cemento de Portland está alrededor de 10%
A reprodu o social da hanseníase: um estudo do perfil de doentes com hanseníase no Município de S o Paulo
Helene Lúcia Maria Fraz?o,Salum Maria Josefina Leuba
Cadernos de Saúde Pública , 2002,
Abstract: Tomamos como objeto de estudo a rela o trabalho-vida de hansenianos sob controle do setor público do Município de S o Paulo, em 1996. Fundamentando-se na teoria da determina o social do processo saúde-doen a, a preocupa o foi a de ampliar o reconhecimento da rede de determina o da hanseníase, buscando produzir conhecimentos que subsidiem a extens o dos projetos de interven o. Foram colhidas informa es junto a uma amostra proporcional de hansenianos - a família como unidade amostral -, classificando-os de acordo com sua inser o social. Os resultados mostram que a maioria dos hansenianos se concentra nos grupos marginalizados da produ o social, deslocados para regi es em que a exclus o social é mais acentuada, diferenciando-se pelo trabalho que realizam. A manter-se a tendência de concentra o dos hansenianos nos estratos intermediário e inferior, renovar-se-á a constru o da hanseníase, tendo como origem os excluídos do Sudeste do Brasil ou os migrantes nordestinos que sobrevivem nos subempregos, na malha periférica da produ o capitalista, pulverizados em trabalhos precários, desqualificados, e no espa o de reprodu o social que parece favorecer um maior acometimento da doen a em jovens e mulheres.
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