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Search Results: 1 - 10 of 3012 matches for " Helen Gilliland "
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A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting
Brian A Trethowan, Helen Gilliland, Aron F Popov, Barathi Varadarajan, Sally-Anne Phillips, Louise McWhirter, Robert Ghent
Journal of Cardiothoracic Surgery , 2011, DOI: 10.1186/1749-8090-6-154
Abstract: A 36 year-old Caucasian male (59 kg, BMI 23.8 kg.m-2) presented for urgent coronary artery bypass grafting 4 weeks after admission to the coronary care unit with a non-ST elevation myocardial infarction. He had episodic chest pain for 1 year increasing in frequency over six weeks prior to admission. On admission to hospital he was commenced on medication including acetylsalicylic acid, Clopidogrel, Elantan LA, Bisoprolol, Ramipril, Ezetimibe and Enoxaparin and he remained as an inpatient until his scheduled surgical procedure without requiring heparin, GTN infusion or inotropes. Urgent coronary angiography revealed a critical lesion of the left main stem artery, 70% stenosis of the proximal circumflex and 70% stenosis of the origin of the posterior descending artery and moderate impairment of left ventricular function with inferoposterior hypokinesis. This impairment in left ventricular was confirmed by transthoracic echocardiography. On arrival in the anaesthetic room his initial blood pressure was recorded as 90/50 mmHg and this had no apparent effect on pre-operative organ function considering all blood tests were within normal range and urine output was >1 ml.kg-1.hr-1. General anaesthesia was induced and was further maintained with propofol target-controlled infusion (1.5μg.ml-1), remifentanil (0.34μg.kg-1.min-1) and isoflurane/oxygen/air mix at FiO2 of 0.4 and end-tidal isoflurane 0.4-0.6%. Peri-operative transoesophageal echocardiography was used as part of monitoring in this case and epi-aortic ultrasound scanning was not utilised. As the left internal mammary artery was being taken down a dose of 250 mg (4.3 mg/kg) of heparin was given with a subsequent ACT of 559s. During CPB mean arterial pressure was maintained between 50-60 mmHg using boluses of phenylephrine and subsequently an infusion of noradrenaline. The lowest recorded mean arterial pressure was 45 mmHg immediately post institution of CPB. The infusion of noradrenaline ran at doses from 0.05-0.075
Evaluating Open Access Day 2009 at Ohio State University
Anne Gilliland
Evidence Based Library and Information Practice , 2010,
Osteoprotegerin Secretion by Mevastatin via p38MAPK and NF-kB  [PDF]
Helen Smith
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2012, DOI: 10.4236/ojra.2012.22006
Abstract: Osteoprotegerin (OPG) is a protein produced by many cell types that has the remarkable property of inhibiting bone loss. It does this by binding to the key bone resorptive cytokine, receptor activator of NF-kB ligand (RANKL). This cytokine is produced mainly by osteoblastic cells and is instrumental in osteoclast differentiation. If the ratio of RANKL:OPG increases, bone resorption increases and results in bone loss in diseases such osteoporosis, rheumatoid arthritis and hypercalcaemia of malignancy. Hence, if drugs can be found that increase OPG, this will decrease the activity of osteoclasts and therefore bone resorption. Statins are cholesterol lowering drugs that have recently been shown to increase bone formation in rodents. It was hypothesised from this finding that this could be due to an increase in OPG production. If these commonly prescribed drugs could be used to prevent bone loss or to increase bone formation then this may prove a useful means of reducing fracture risk in patients. Treating Saos-2 osteoblast-like cells in vitro with mevastatin increased OPG production and secretion through the mevalonate pathway. A failure of geranylgeranylation of Rho and/or farnesylation of Ras proteins leads to an increase in PI-3K activation then AKT activation leading to several different signaling pathways such as MAPK’s and NF-kB. NF-kB and p38MAPK inhibitors prevented the statin stimulation of OPG but not the decrease in cell number, suggesting that statins regulate OPG secretion via PI-3K, p38MAPK and NF-kB.
Religious Wear (Uniforms) in Psychiatry  [PDF]
Helen Bright
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.42015

Uniforms represent more than just a body cover. There could be symbols of status, power, authority, values, beliefs, identity, wealth representation, self-protection, health and safety, suppression of individuality and identification on one hand by the wearer. The observers may perceive uniforms differently based on their experiences, expectations, education, perceptual ability, conformity, status, power, self-confidence, and need for trust and communication without barrier or judgment. Forty five adult mentally ill patients (21 female and 24 male) were administered questionnaires with Linkert Scale regarding how approachable or off-putting they find casual and religious wear in social worker. Significantly more patients preferred casual wear to religious. Chi squared test equals 28.689 with p value of less than 0.0001 for four degrees of freedom.

The Influence of L2 Transfer on L3 English Written Production in a Bilingual German/Italian Population: A Study of Syntactic Errors  [PDF]
Helen Forsyth
Open Journal of Modern Linguistics (OJML) , 2014, DOI: 10.4236/ojml.2014.43036

This study attempts to examine and identify instances of negative “interlanguage transfer” (Sharwood Smith & Kellerman, 1986), which is a phenomenon belonging to the broader field of crosslinguistic influence, in written L3 English production in a bilingual Italian/German population. Transfer from learners’ L2 has attracted increasing attention over recent years (De Angelis & Selinker, 2001; Jessner, 2006) and research has suggested various potential triggers for facilitative and negative L2 transfer, as well as producing mixed results regarding the individual aspects of language that may be susceptible to transfer from a learner’s L2. Quantitative data were collected from 46 subjects in the form of questionnaires enquiring about language backgrounds and attitudes, and written summaries. The Statistical Package for Social Science was used to analyse specific instances of written syntactic errors resulting from both L1 and L2 transfer and these were then examined in the light of the questionnaire responses in order to identify possible determining factors behind any L2 transfer for both linguistic groups. Results provided evidence of negative syntactic L2 transfer from German and Italian in English L3, yet the possible determining factors were sometimes unexpected and not necessarily identical for both groups. This study suggests that L2 transfer in multilingual settings is a very real possibility which may be of future interest in terms of multilingual language processing and have consequences for the L3 classroom.

Designing Economics Electives with a Significant Writing Component  [PDF]
Helen Schneider
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.84040
Abstract: This paper presents a design for the structure and assessment of a research paper assignment in an upper level economics elective with a significant writing component. Writing component design focuses on what graduating economics majors should be able to do with the knowledge they acquire in the major and on their ability to create original analysis and empirical models in courses with and without an econometrics prerequisite. The author provides writing workshop and minimal marking approaches to improving the writing skills of undergraduates. Finally, the paper presents the link between main modules of the course and proficiencies we expect from graduating majors.
Mapping the evolution of 'food deserts' in a Canadian city: Supermarket accessibility in London, Ontario, 1961–2005
Kristian Larsen, Jason Gilliland
International Journal of Health Geographics , 2008, DOI: 10.1186/1476-072x-7-16
Abstract: The findings indicate that residents of inner-city neighbourhoods of low socioeconomic status have the poorest access to supermarkets. Furthermore, spatial inequalities in access to supermarkets have increased over time, particularly in the inner-city neighbourhoods of Central and East London, where distinct urban food deserts now exist.Contrary to recent findings in larger Canadian cities, we conclude that urban food deserts exist in London, Ontario. Policies aimed at improving public health must also recognize the spatial, as well as socioeconomic, inequities with respect to access to healthy and affordable food. Additional research is necessary to better understand how supermarket access influences dietary behaviours and related health outcomes.A growing body of research suggests that the suburbanization of food retailers in North America and the United Kingdom in recent decades has contributed to the emergence of urban 'food deserts', that is, socially-distressed neighbourhoods with relatively low average household incomes and poor access to healthy food [1]. While more and more large-format supermarkets are erected on suburban lands, smaller grocers in older central-city neighbourhoods seem to be rapidly disappearing, leaving potential food deserts in their wake. This paper explores the historical and geographical evolution of supermarket access in a mid-sized Canadian city: London, Ontario, 1961–2005.Why examine access to supermarkets? A healthy diet can reduce the risk of many chronic diseases [2]. The majority of these health problems can be linked to a diet with low fruit and vegetable consumption [3,4] and eating large amounts of sugary or high fat foods [5]. National surveys indicate that most Canadians shop for food at a local supermarket, where the widest variety of products can be found at the most competitive prices [6]. While supermarkets also carry unhealthy foods (e.g., chips, soft drinks, and processed foods), these items are more readily availabl
Prelude to, and Nature of the Space Photometry Revolution
Ronald L. Gilliland
Physics , 2014, DOI: 10.1051/epjconf/201510100001
Abstract: It is now less than a decade since CoRoT initiated the space photometry revolution with breakthrough discoveries, and five years since Kepler started a series of similar advances. I'll set the context for this revolution noting the status of asteroseismology and exoplanet discovery as it was 15-25 years ago in order to give perspective on why it is not mere hyperbole to claim CoRoT and Kepler fostered a revolution in our sciences. Primary events setting up the revolution will be recounted. I'll continue with noting the major discoveries in hand, and how asteroseismology and exoplanet studies, and indeed our approach to doing science, have been forever changed thanks to these spectacular missions.
Decision making in civil disputes
Victoria Gilliland,John C. Dunn
Judgment and Decision Making , 2008,
Abstract: The present study investigates the effect of framing and legal role on the propensity to accept a settlement offer by litigants in a simulated legal dispute. Participants were given four different scenarios that factorially combined legal role (plaintiff vs. defendant) and frame (positive vs. negative). The results indicated that positively framed litigants were more willing to settle than negatively framed litigants independently of legal role. These results were replicated in a second experiment that also asked participants to state their subjective probability of winning. This revealed that the propensity to settle was a joint function of frame and the perceived chance of winning. In contrast to previous research, no systematic effect of legal role was found. It is concluded that the rate of negotiated settlements of legal disputes may be increased by manipulating both of these factors.
Solar-like oscillations in a metal-poor globular cluster with the HST
D. Stello,R. L. Gilliland
Physics , 2009, DOI: 10.1088/0004-637X/700/2/949
Abstract: We present analyses of variability in the red giant stars in the metal-poor globular cluster NGC6397, based on data obtained with the Hubble Space Telescope. We use an non-standard data reduction approach to turn a 23-day observing run originally aimed at imaging the white dwarf population, into time-series photometry of the cluster's highly saturated red giant stars. With this technique we obtain noise levels in the final power spectra down to 50 parts per million, which allows us to search for low amplitude solar-like oscillations. We compare the observed excess power seen in the power spectra with estimates of the typical frequency range, frequency spacing and amplitude from scaling the solar oscillations. We see evidence that the detected variability is consistent with solar-like oscillations in at least one and perhaps up to four stars. With metallicities two orders of magnitude lower than of the Sun, these stars present so far the best evidence of solar-like oscillations in such a low metallicity environment.
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