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Search Results: 1 - 10 of 754 matches for " Heba Salam "
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Role of toll receptors in diabetic nephropathy  [PDF]
Mona Mansour, Randa Fayez Salam, Lila Rashed, Heba Salam
Journal of Diabetes Mellitus (JDM) , 2014, DOI: 10.4236/jdm.2014.41005
Abstract:

Objectives: Diabetic nephropathy is the leading cause of chronic kidney disease. The pathogenesis of DN remains incompletely understood. It has been recently demonstrated that inflammatory processes play a significant role in the development and progression of DN. Toll-like receptors play a fundamental role in the innate immune system by triggering proinflammatory signaling pathways. Our aim is to evaluate the expression of TLRs on monocytes and relate their expression with inflammation in HD patients with & without diabetic nephropathy. Method: In a case control study (60) patients from Alkasr El Aini Hospital on hemodialysis were divided into two groups: Group 1, 30 patients on heamodialysis not due to diabetic nephropathy, Group 2, 30 patients on heamodialysis due to diabetic nephropathy, compared to Group 3, including 30 healthy controls. All participants were subjected to: Full medical history, complete physical examination, Serum creatinine, uric acid, A1C, fundus examination, detection of TLR2, TLR expression by real time PCR in peripheral blood mononuclear cells. Data were statically calculated using SPSS, comparision between groups was done using student T test comparing 2 groups, correlation using spearman’s correlation. Results: Diabetic had significantly increased TLR2, TLR4 mRNA in peripheral blood mononuclear cells compared to controls and non diabetics patient on heamodialysis (p < 0.001), TLR2, TLR4 significantly correlated with dialysis duration in diabetic (p < 0.001), no correlation with A1C in relation to TLR2 (p = 0.078), TLR4 (p = 0.163). Conclusion: TLR2, TLR4 were significantly elevated in diabetic on dialysis initiating event in the pathogenesis of DN, providing a link between hyperglycemia and hypoxia with inflammation and fibrosis within the kidney. Hence, therapeutic interventions aimed at targeting the inflammatory component through interruption of TLR signaling may be a novel strategy to target prevention and treatment of DN.

Interactive Effect of Forage Mixing Rates and Organic Fertilizers on the Yield and Nutritive Value of Berseem Clover (Trifolium alexandrinum L.) and Annual Ryegrass (Lolium multiflorum Lam.)  [PDF]
Heba Sabry Attia Salama
Agricultural Sciences (AS) , 2015, DOI: 10.4236/as.2015.64041
Abstract:

Berseem clover (Trifolium alexandrinum L.) is the main winter forage legume in Egypt. Despite that the yield and protein content of berseem clover are high, it is characterized by low dry matter content especially in the 1st cut. Intercropping berseem clover with forage grasses, especially annual ryegrass (Lolium multiflorum Lam.) is a recommended technique to produce higher forage yield with better balanced nutritional quality. However, little is known about the performance of these proposed mixtures under the arising organic farming system in Egypt. Organic farming and the application of organic fertilizers (compost and poultry manure) are receiving increased attention in the last few years. Thus, the current study was carried out on the winter season of two successive years (2012 and 2013) in the experimental station of SEKEM organic farm, Egypt. Main aim was to investigate the variation in 1st cut forage yield and nutritive value of berseem clover and annual ryegrass, grown in pure stands and with three mixing rates, under three organic fertilization regimes (compost, poultry litter, and no fertilization). Nutritive value was judged through investigating the crude protein (CP), total carbohydrates (TC), and fiber fractions (NDF, ADF, and ADL). Results revealed significant two-way interaction between the forage treatments and the fertilization regimes for all the studied parameters. In general, mixing berseem clover with annual ryegrass, fertilized by compost or poultry litter resulted in significantly higher forage yield, dry matter content, and balanced CP, TC, and fiber fractions, compared to the pure stands.

Ameliorative Effects of Spirulina platensis on Deltamethrin-Induced Biochemical Alterations and Oxidative Stress in the African Catfish; Clarias gariepinus  [PDF]
Heba S. Hamed
Open Journal of Marine Science (OJMS) , 2016, DOI: 10.4236/ojms.2016.61001
Abstract: The present study was carried out to determine LC50 of deltamethrin (DM) in the African catfish; Clarias gariepinus, investigate its effects on the biochemical parameters and the antioxidant status of various tissues, and assess the protective role of Spirulina platensis (SP) against DM induced toxicity in C. gariepinus. The fish were distributed into seven groups of 10 fish/each for 30 days as follows: Group 1, control; Group 2, orally administered saline; Group 3, oral SP (150 mg/kg b.w.); Group 4, exposed to 5.19 μg/l DM; Group 5, exposed to 5.19 μg/l DM and orally administered SP (150 mg/kg b.w.); Group 6, exposed to 12.97 μg/l DM; and Group 7, exposed to 12.97 μg/l DM and orally administered SP (150 mg/kg b.w.). Results revealed marked elevation in serum AST, ALT, ALP, creatinine, urea and uric acid. Significant decrease in serum total protein and albumin was recorded. At the same time, the level of malondialdehyde (MDA) was significantly increased in liver, kidney and gills. While, tissue level ofGSHand, SOD,CATandGSH-Px activities were reduced. Treatment with SP improved the biochemical parameters and attenuated the DM induced oxidative damage. Therefore, this study confirmed the protective role of SP as an antioxidant against the toxicity of DM in catfish.
Scottish Primary School Children Who Consume Greater Levels of Fruit and Vegetables Have Improved Health Markers  [PDF]
Heba Althubaiti, Madeline Coleman
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.85034
Abstract: Background: There is conflicting information about whether Scottish children follow the UK government recommendation of consuming 5 portions of fruit and vegetable (F & V) a day, or whether increased intake of F & V promotes improved health. Objective: This study aimed to 1) perform a cross-sectional study of the number of F & V portions that primary school children consume in relation to age (4 - 13 years old) and sex, 2) establish the relationship between F & V intake and health parameters. Methods: Data were collected from 466 children using a specific F & V intake questionnaire. Health parameters (weight, height, blood pressure, waist circumference, hip circumference and lung function) were measured from all of the children. Results: Children consumed on average a total of 4.50 (SD 1.86) portions of F & V per day. F
Analysis of Social, Psychological and Other Factors on College Dropout Rates among African American Students  [PDF]
Salam Khan
Advances in Applied Sociology (AASoci) , 2017, DOI: 10.4236/aasoci.2017.78020
Abstract: This study explored the African American college students’ retention behavior and identifies the effect of different social, psychological and other factors. Randomly selected students from predominant African American university completed the perceived stress scale, self-motivation scale, parental involvement, childhood economic situation, mentorship and drug and alcohol use questionnaire. Non-parametric analyses suggested that higher stress level, childhood poverty, lack of parental involvement or support, without a mentor support and lack of self-motivation increase the likelihood of dropping out from college. This study’s findings have important implications for college retention among African American students.
Self-rated health and factors influencing responses among young Egyptian type 1 diabetes patients
Heba Ismail
BMC Public Health , 2011, DOI: 10.1186/1471-2458-11-216
Abstract: The standardized SRH measure was the instrument used for health related quality of life assessment. Logistic regression analysis was used to examine the association between SRH responses and selected variables.124 subjects, 64 females (51.6%) and 60 males (48.4%) were included. Average age was 13.08 (±3.19) and average diabetes duration was 5.82 (±1.60), while the mean HbA1C was 8.02 (±1.60). The majority rated their health as good (31%), 29% rated it as excellent, 11% as very good, 14% as poor and 15% as very poor. Regression analysis showed that regular exercise was the only predictor that was independently and significantly associated with a "better" self-health rating, with an OR of 12.84, CI of 1.425-115.727 and a p value of 0.023.Regular exercise among Egyptian children with T1DM is strongly associated with a "better" overall health related quality of life and should be repeatedly encouraged.Diabetes mellitus affects nearly 3.9 million individuals in Egypt with an expected increase by 2025 to nearly 9 million [1]. This is a significant number, making health-related quality of life (HRQoL) among individuals with diabetes a public health goal.Patients diagnosed with type 1 diabetes mellitus (T1DM) face major lifestyle changes and the risk of experiencing debilitating and life-threatening complications. The daily management of diabetes in and of itself presents numerous challenges to achieve adequate metabolic control; from multiple daily injections and frequent blood glucose monitoring to routine laboratory work, frequent healthcare visits, and careful regulation of exercise and meal schedules. Moreover, patients with T1DM are at increased risk for major depression, anxiety, and eating problems [2]. Considering T1DM is commonly diagnosed in children and young adults, the effect of these challenges become more pronounced as they accompany these young individuals for many decades to come. It is therefore essential that care for T1DM both alleviate the physical com
Assessment of Surfactant Modified Activated Carbon for Improving Water Quality  [PDF]
Kamoru A. Salam
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2019, DOI: 10.4236/jeas.2019.91002
Abstract: Effluents containing inorganic contaminants are releasing into the environment untreated despite being hazardous to man and environment. It is costly and unsustainable to use conventional methods to remove them from dilute aqueous solution. Adsorption involving granular activated carbon is an alternative method for treating such effluents. Granular activated carbon is structurally strong, highly resistance to attrition and wearing, large and can easily separate from the effluents. However, its surface is highly hydrophobic and has little surface charge thereby reducing its adsorption capacity for anion or cation. This article reviews surfactant modification of activated carbon to enhance its adsorption capacity for inorganic contaminants and key factors affecting the adsorption efficiency. They include initial concentration of contaminants, contact time, solution pH, solution temperature, adsorbent concentration, ionic strength, competing ions, type of surfactant, and surfactant concentration. The modified activated carbon usually shows maximum contaminant uptake around its critical micelles concentration. Surfactant modification reduces specific surface area and/or micro pore volume but hot NaOH or HNO3 treatment before surfactant modification minimises this drawbacks and increases the net surface charge. Overall, surfactant modification is a simple but efficient method of enhancing adsorption capacity of activated carbon for removing anion or cation from aqueous solution. However, a handful publication is available on the regeneration of the spent (saturated) surfactant modified activated carbons. Hence, more research efforts should be directed towards proper regenerating reagents and the optimise conditions such as contact time, concentration, and temperature for regenerating spent modified activated carbons.
Proposed Framework for Security Risk Assessment  [PDF]
Zakaria I. Saleh, Heba Refai, Ahmad Mashhour
Journal of Information Security (JIS) , 2011, DOI: 10.4236/jis.2011.22008
Abstract: Security risk assessment framework provides comprehensive structure for security risk analysis that would help uncover systems’ threats and vulnerabilities. While security risk assessment is an important step in the security risk management process, this paper will focus only on the security risk assessment framework. Viewing issues that exist in a current framework, we have developed a new framework for security risk and vulnerabilities assessment by adding new components to the processes of the existing framework. The proposed framework will further enhance the outcome of the risk assessment, and improve the effectiveness of the current framework. To demonstrate the efficiency the proposed framework, a network security simulation as well as filed tests of an existing network where conducted.
Effect of Calcium and Phosphorus on Nonhaeme Iron Absorption and Haematogenic Characteristics in Rats  [PDF]
Heba Ezz El-Din Yossef
Food and Nutrition Sciences (FNS) , 2010, DOI: 10.4236/fns.2010.11003
Abstract: The objectives of this study were to use the dry thyme leaves as source of nonhaeme iron and evaluate the effects of calcium, phosphorus and calcium + phosphorus on nonhaeme iron absorption and haematogenic characteristics in rats. Thirty adult male albino rats, weighing 150 ± 5 g were divided into five groups. The first group fed basal diet, the second group fed thyme diet, the third group fed thyme diet + calcium, the fourth group fed thyme diet + phosphorus and the fifth group fed thyme diet + calcium + phosphorus. All groups fed experimental diets for six weeks. Hemoglobin (Hb), haematocrit (Ht), red blood cell (RBC), mean corpuscular volume (MCV), serum iron (SI), serum ferritin (SF), total iron–binding capacity and transferrin saturation were determined at the beginning and the at end of the experiment. Iron in diet, Fe intake, Fe feces and Fe absorption were also evaluated. The results indicated that the lowest Fe absorption was observed in rats fed the thyme diet + calcium and thyme diet + calcium + phosphorus. Supplementation the thyme diet with calcium or calcium + phosphorus decreased the values of Hb, Ht, RBC, SI and SF. However, supplementation the thyme diet with phosphorus did not affect in Ht, RBC and MCV but Hb, SI and SF increased. The results suggest that supplementation the diet with calcium or calcium + phosphorus interfere with iron absorption.
The Role of Replacing CdO by Fe2O3 on the Fast Neutron Removal Cross Sections in Cd-Boro Phosphate Glass Shield  [PDF]
Hanaa A. Sallam, Heba A. Saudy
World Journal of Condensed Matter Physics (WJCMP) , 2013, DOI: 10.4236/wjcmp.2013.31011
Abstract:

This work deals with the application of [MERCSF-N] computer program in calculating the macroscopic effective removal cross-section of fast neutrons, ΣR (cm-1), for two different boro phosphate glass systems: (0.5 - x) CdO-x Fe2O3-0.4 P2O5-0.1 B2O3 and (0.5 - x) B2O3-x Fe2O3-0.1 CdO-0.4 P2O5 (with 0.05 x 0.5 by

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