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Search Results: 1 - 10 of 848 matches for " HM Afify "
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Tissue factor pathway inhibitor in paediatric patients with nephrotic syndrome
FA Farid, AA Mohammed, RS Beltagi, HM Afify
South African Journal of Child Health , 2011,
Abstract: Background. Tissue factor pathway inhibitor (TFPI) is an endogenous protease inhibitor that regulates the initiation of the extrinsic coagulation pathway by producing factor Xa-mediated feedback inhibition of the tissue factor/factor VIIa (TF/VIIA) catalytic complex. Objectives. To evaluate plasma TFPI levels in paediatric patients with nephrotic syndrome (NS) and its correlation with disease activity. Subjects and methods. Fifteen nephrotic patients in relapse (proteinuria >40 mg/m2/h, hypo-albuminaemia and oedema) before initiating steroid therapy (group I) and another 15 nephrotic patients in remission after withdrawal of steroid therapy (group II) were compared with 15 age- and sex-matched healthy children (group III). Besides clinical evaluation and routine laboratory investigations of NS, tissue factor pathway inhibitor levels in plasma were measured by enzyme-linked immunosorbent assay (ELISA). Results. The plasma TFPI level was higher in nephrotic patients during relapse (group I) and during remission (group II) (mean 102.53 (standard deviation (SD) 14.23) and 82.93 (SD 3.83) ng/ml, respectively) compared with that in the control group (62.40 (SD 7.53) ng/ml) (p<0.0001). In children with NS the plasma TFPI level was higher during relapse (group I) compared with the level in remission (group II) (p<0.0001). There was a negative correlation between the plasma TFPI level and total protein and serum albumin, and a positive correlation between the plasma TFPI level and the urinary protein/creatinine ratio (p<0.05). Conclusion. NS was associated with increased level of plasma TFPI in comparison with the control group, and the increase was more apparent in patients with active disease.
Symposium on the role of archives in writing the history of nations and peoples
Ali Afify
Historical Kan Periodical , 2012,
Abstract: " " 2012 . . . " ".
Order Statistics from Pareto Distribution
El desoky E. Afify
Journal of Applied Sciences , 2006,
Abstract: In this study, we derive some recurrence relations of single and product moments of order statistics from Pareto distribution. We estimate the parameters of the distribution using the moment of order statistics. We compute the mean, variance and coefficient of variation of order statistics from Pareto distribution.
Fine Scale Precipitates in Al-Mg-Zn Alloys after Various Aging Temperatures  [PDF]
Nasser Afify, Abdel-Fattah Gaber, Ghada Abbady
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.25056
Abstract: This article deals with investigation of fine-scale precipitation in Al-Mg-Zn alloys with compositions of Al - 2 at% Mg- x at% Zn, (x = 1.8, 2 and 4.2). The precipitates morphology was examined by scanning electron microscope (SEM) and correlated with the microhardness (HV) and differential scanning calorimetry (DSC) of the specimens. The precipitates are characterized as h’ (MgZn2) and h (MgZn2) phases of hexagonal structure of the same composition with a slight difference in lattice parameters. In addition, T-phase pf composition (Mg32 (Al, Zn)49) having a cubic crystal structure. Owing to the determined activation energies of the precipitates, the kinetics associated with their nucleation and growth can be characterized. The thermal energy acquired during aging leads to the agglomeration of precipitates to or larger particle sizes.
Heat shock proteins development in different stages of schistocerca gregaria as response to heavy metals intoxication  [PDF]
Hesham A. Yousef, Amira Afify, Afaf Abdel Meguid, Hany M. Hassan
Natural Science (NS) , 2011, DOI: 10.4236/ns.2011.33028
Abstract: The induction of heat shock proteins in different stages of S. gergaria exposed to long and short term contamination with heavy metals, Cd and Pb in food was determined, revealing a prominent variable effect in response to the term of exposure and the type of contamination. HSP 70 was specially quantified and characterized to reveal the probability of using HSP as a biomarker for pollution.
DNA damage in hemocytes of Schistocerca gregaria (Orthoptera: Acrididae) exposed to contaminated food with cadmium and lead  [PDF]
Hesham A. Yousef, Amira Afify, Hany M. Hasan, Afaf Abdel Meguid
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.24037
Abstract: We measured in a comet assay the damage of DNA in the hemocytes of various stages of the grasshopper Schistocerca gregaria after ex-posing them to various doses of Cd and Pb in the food. The mechanisms of Cd and Pb toxicity for grasshopper are discussed. The accumula-tion of heavy metals and stage of the insect may play important roles in causing the DNA damage. S. gregaria may be considered a valuable bio-indicator for evaluation the genotoxicity of en-vironmental pollutants.
Comparative Response of C3 and C4 Cereal Plants and Soil Azospirillum Spp. Distribution to Bacterization and N-fertilization
F.M. Hammouda,Aida H. Afify
Pakistan Journal of Biological Sciences , 1999,
Abstract: Four greenhouse experiments to assess the response of two physiologically different cereal crops, i.e. sorghum and rice crops representing C4 and C3 plants as well as Azospirillum spp. populations in their rhizosphere and root surface soil to inoculation with A. lipoferum in combination with five levels of N fertilizer were conducted. The results indicated that sorghum was more responsive to inoculation than rice plant. Maximum benefits were obtained when the N fertilizer level was reduced to 30 kg/fed. in combination with A. lipoferum inoculant, giving the superiority in yields and yields components of both plants. There was a moderate difference of the rhizosphere and root surface soil effect on Azospirillum spp. population density between the two different groups of plants. However, MPN of Azospirillum spp. surrounded the root system of C4 plant recorded greater value than that of C3 one.
Effect of Regional Epidural Ropivacaine Anesthesia on α Glutathione-S-Transferase: Comparison with Low Flow Sevoflurane and Total Intravenous Propofol Anesthesia
Waleed Hamimy,Esmat Ashour,Mie Afify
Journal of Biological Sciences , 2004,
Abstract: This study presents the liver affection following low flow Sevoflurane anesthesia, total intravenous propofol anesthesia and regional epidural ropivacaine anesthesia in patients undergoing hysterectomy by using glutathione-S-transferase (α-GST) as a sensitive indicator of hepatocellular integrity as compared to the conventional liver enzypostoperative) and the measurements of blood glucose level, renal function tests, conventional liver enzymes and serum α-GST were done for all subjects. The results showed that, the conventional liver enzymes did not show any significant changes between the three studied groups, while the α-GST showed statistical significant difference between the three studied groups in the 2 h postoperative. Α GST concentration was significantly increased in group I in the 2 h postoperativemes. The study conducted on 45 healthy patients ASA I or II, scheduled for abdominal hysterectomy were randomly allocated into three equal groups. Group I received low flow Sevoflurane anesthesia, Group II received total intravenous propofol anesthesia and group III received regional epidural ropivacaine anesthesia. Three blood samples were drawn from each patient (preoperative, 2 and 24 h samples as compared to preoperative values and two other groups. While, in group II and group III there were no significant increase as compared to the preoperative values, although in group III the concentration of α-GST decreased but not significantly in the 2 h postoperative sample mostly due to hydration of the patients by the preloading fluid. The finding from this study suggest that, the epidural anesthesia has the least effect on liver functions especially when it was assessed by α-GST which is more specific and sensitive index for hepatic injury than the conventional liver enzymes. Epidural anesthesia should be considered as the anesthetic technique of choice forabdominal hysterectomy. Propofol also led to minimal effect on α-GST and a better quality of recovery than sevoflurane anesthesia, which caused mild elevation in GST and this may limit its use in patients with hepatic dysfunction.
Clinical Evaluation of Some Biochemical Markers in Multiple Myeloma among Egyptian Patients
Magda Sayed,Mie Afify Mohammed,Ola Khorshid
Journal of Medical Sciences , 2007,
Abstract: The objective of the current study was to evaluate the circulating levels of mediators such as interleukin-6 (IL-6), β-2 microglobulin (β2-M), lactate dehydrogenate (LDH), total alkaline phosphatase (TALP), bone alkaline phosphatase (BALP) and C-reactive protein (CRP) before and after treatment in patients with MM. Testing these biochemical markers might help in the identification, staging, determining its severity and monitoring the response to treatment of the myeloma patients. It was determined serum levels IL-6, β2-M, LDH, TALP, BALP and CRP in 28 newly diagnosed (group I) and 23 after treatment (group II) in patients with MM. The mean age of the patients was 59.63 and 61.55 years, respectively. All patients were in stage III (classified according to the Durie-Salmon classification). The same parameters were measured in 15 healthy controls with a mean age of 58.06 years. The results showed that the serum levels of IL-6 (pg mL1), beta-2 microglobulin (μg mL1), CRP (mg mL1) and LDH (U L1) were increased in-group (I) and this increment were highly significant (p< 0.001) on comparison with the control group and group (II). The serum level of TALP and BALP (U L1) were increased in-group (I) and this increment was slightly significant (p< 0.05) on comparison with the control group and group (II). All of the parameters were found to be significantly reduced after chemotherapy treatment. The serum level of T ALP in-group (II) decreased but did not reached the normal value and there was significant increased as compared to the control group (p< 0.05). There were a significant positive correlation (p< 0.05) between serum level of IL-6 and beta-2 microglobulin, CRP, LDH, TALP and BALP, the r-values were 0.7319, 0.6875, 0.7528, 0.8119 and 0.7072, respectively in-group (I). In conclusion, It was found that after the therapy, the levels of these parameters, which are thought to play an important role in the pathogenesis of MM, were significantly suppressed denoting their importance in the prognosis and monitoring the MM disease.
The Prevalence of Dental Anomalies in the Western Region of Saudi Arabia
Ahmed R. Afify,Khalid H. Zawawi
ISRN Dentistry , 2012, DOI: 10.5402/2012/837270
Abstract: Objective. The aim of this cross-sectional study was to investigate the prevalence of dental anomalies that could be a cause of malocclusion in the western region of Saudi Arabia. Materials and Methods. A retrospective study of 878 digital orthopantomograms (OPGs) taken of patients, age ranging between 12 and 30 years, who presented to treatment at the Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia between 2002 and 2011. The OPGs and dental records were reviewed for congenitally missing teeth, supernumerary teeth, impactions, ectopic eruption, transposition, germination, fusion, dilacerations, taurodontism, dens in dent, and any other unusual conditions that can be assessed with OPG. Results. The prevalence of patient that exhibited at least one dental anomaly was 396 (45.1%) patients. The prevalence of congenitally missing teeth was 226 (25.7%), impacted teeth 186 (21.1%), dilacerated teeth 10 (1.1%), supernumerary teeth 3 (0.3%), odontoma 1 (0.1%), and taurodontism was also 1 case (0.1%) of the total radiographs reviewed. Conclusions. Congenitally missing teeth were found to be the most prevalent anomaly (25.7%), and the second frequent anomaly was impacted teeth (21.1%), whereas root dilacerations, supernumerary teeth, and taurodontism were the least frequent anomalies (1.1%, 0.3% and 0.1%, resp.). 1. Introduction Dental anomalies in tooth number, shape, and position usually result in problems in maxillary and mandibular arch length and occlusion, which may greatly influence orthodontic treatment planning. The etiology of these conditions is usually attributed to certain genes in addition to some etiological events in the prenatal and postnatal periods that may result in anomalies in tooth size, shape, position, number, and structure [1–5]. Congenitally missing teeth constitute the most common developmental anomaly of the human dentition, occurring in approximately 25% of the population, and the wisdom tooth represents the most affected tooth (20.7%) [6]. Excluding third molars, the prevalence of tooth agenesis is approximately 4.3 to 7.8%, and the mandibular second premolars are the most commonly missing teeth, followed by the maxillary lateral incisors and maxillary second premolars [7]. Ethnic background was found to have an effect on the prevalence of tooth agenesis. Epidemiological studies revealed a lower prevalence of agenesis in the Black race compared to the White race, while Asians showed increased tooth agenesis compared to Whites [7]. Sexual differences were also reported in the prevalence of tooth agenesis, where
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