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Search Results: 1 - 10 of 149737 matches for " H. Godonou "
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Peptic Ulcer Disease in CHUYO  [PDF]
A. Coulibaly, A. K. Sermé, H. Godonou, K. S. Somda, K. Cissé, Sia Romond, Kafando Roch, R. A. Sombié, A. Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.611038
Abstract: Background: Prevalence of Peptic Ulcer Disease (PUD) is decreasing in developed countries since the use of the treatments for eradication of Helicobacter pylori. Objectives: To revalue the sociodemographic, clinical and evolutionary aspects of the PUD among hospitalized patients in CHUYO. Methodology: This prospective study is related to 65 files of patients hospitalized in hepato-gastroenterology and general surgical services of the CHUYO between March 1st and August 31st, 2015. Results: Hospital utilization rate was 6.59%. The average age of patients was 40.6 years with extremes of 17 and 80 years. The sex ratio was 9.8. The location of the ulcer was 69.23% in stomach. A notion of taking aggressive gastrointestinal products was found in 62 patients (95.4%). The clinical picture was represented by diffuse abdominal pain (76.92%), peritoneal irritation syndrome (64.61%) and epigastric pain (56.92%), anemia (23.07%). Gastric perforations (64.61%) and gastrointestinal bleeding (12.30%) were the main complications. Consumption of non-steroidal anti-inflammatory drugs (NSAIDs) was found in 81.5% of cases. The management was medical and/or surgical with an overall mortality rate of 7.7%. Conclusion: The PUD rate decreased from 10.12% to 6.59% in 5 years. The complications are dominated by stomach perforations. They are relative increase and seem related to NSAIDs. Better management of this disease requires awareness of the population to self-medication.
Epidemiological, Clinical, Biological, Therapeutic Features and Outcome of Congenital Malaria at the Borgou Regional University Teaching Hospital (CHUD-B) in Benin in 2015  [PDF]
Godonou Gratien Sagbo, Alphonse Noudamadjo, Joseph Agossou, Julien Didier Adedemy, Awade Achille Obossou, Djewessi Saturnin Lokossou
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.74030
Abstract: Background: The prevalence of congenital malaria is getting more and more significant in Sub-Saharan Africa where is a malaria-endemic area. This study aimed to identify the clinical and therapeutic features as well as the outcome of congenital malaria in CHUD-B in 2015. Method: It was a cohort and descriptive study with analytical purpose, carried out in the Mother and Child Department which includes the Gynecology & Obstetrics and Pediatric Unit of CHUD-B. The study target population consisted of all the infants born in the CHUD-B as well as their mothers. The main variable was the presence of congenital malaria. The independent variables were those related to clinical, therapeutic features and outcome. Results: In the study, among the 300 newborns registered, 57 carried congenital malaria i.e. a prevalence of 19%. 171 (57.0%) of them were males versus 129 (43.0%) females. Among the 281 mothers involved, 48 presented with malaria in pregnancy i.e. a prevalence of 17.0%. At the end of this research work, the factors associated with congenital malaria were fever in the 3rd quarter and malaria in pregnancy in the mother. Conclusion: Nearly one out of five infants born in the CHUD-B was carrier of congenital malaria and approximately one out six mothers presented with malaria detection during pregnancy. A method based on Polymerase Chain Reaction
Benefits of Artesunate versus Quinine in the Treatment of Children with Severe Malaria at the National University Teaching Hospital of Cotonou  [PDF]
Godonou Gratien Sagbo, Laeticia Zohoun, Gilles Bognon, Joseph Agossou, Caroline Padonou, Yévèdo Tohodjèdé, Florence Alihonou, Blaise Ayivi
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.73019
Abstract: Introduction: Severe malaria is one of the leading causes of death in Sub-Saharan African countries, and artesunate is recommended as a first-line treatment by the Word Heath Organization (WHO.). Objective: Identify the advantages of artesunate compared with quinine in the treatment of severe malaria in children. Methods and patients: This study was a cross-sectional, descriptive and analytical study focused on children hospitalized for severe malaria in the CNHU who were treated with quinine or artesunate. Findings: The hospital-based frequency rate of severe malaria in pediatric patients was estimated to be 28.3% (n = 848). One hundred five children were treated with artesunate, and 743 were treated with quinine. The mean age of the children was 47 months old. The primary signs of severity were anemia (n = 776), neurological manifestations (n = 309) and hemolysis (n = 137). The average duration of treatment was 1.95 days for artesunate versus 2.45 days for quinine, and the difference was statistically significant (p = 0.001). The average length of stay (ALOS) in the hospital was 5 days for the artesunate group versus 5.75 days for the quinine group, and the difference was statistically significant (p < 0.001). Six of the children who received artesunate died, whereas 24 children who treated with quinine died. The total average cost of healthcare was 50,600 FCFA (77 euros) per child treated with artesunate versus 57,100 FCFA (87 euros) per child treated with quinine. Conclusion: The treatment of severe malaria with artesunate is superior to quinine-based treatment.
Satisfaction of Patients Treated in Physical Medicine and Rehabilitation Department in CNHU-HKM of Cotonou  [PDF]
Hountondji Etienne Alagnide, Didier Niama Natta, Germain Houngbedji, Mireille Adido, Jean Olouka, Eric Havyarimana, Godonou Toussaint Kpadonou
Open Journal of Therapy and Rehabilitation (OJTR) , 2018, DOI: 10.4236/ojtr.2018.61002
Abstract: Satisfaction of patients is an important dimension of the hospital management and the evaluation of the quality of care and services offered to patients. Objective: To estimate the degree of satisfaction of patients admitted in Physical Medicine and Rehabilitation Department in the National Hospital and University Center (CNHU-HKM) in Cotonou. Method: Cross-sectional study with descriptive and analytical aim. It was led from June 15th to October 15th 2013, on 158 patients or guides of children or not communicating patients having ambulatory care in the Department of Physical Medicine and Rehabilitation and who agree to participate to the study. The level of global satisfaction of the subjects was estimated with a digital scale from 0 to 10. It was secondarily transformed into a discreet qualitative variable. Result: Rate of participation was 63.2%. Patients had deficiencies of rheumatilogical origine (41.1%), neurological (27.2%), traumatological (24.1%). Their pathologies were evolving since 1 month to 10 years. It was about their first attendance of the Rehabilitation Department of CNHU-HKM in 72.2%. Patients’ degree of satisfaction was good for the deadliness of expectation, reception (80%), cleanliness of the building, respect of patients’ intimacy. Global satisfaction of patients was good in 72%. It was influenced by the deadline of evolution of the pathologies. Discussion-Conclusion: The level of satisfaction of patients admitted in the Rehabilitation Department in CNHU-HKM was acceptable. However, they are parameters that remain to be improved.
Uterine Perforation after Pose of IUD, the Place of Abdomen Radiography without Preparation  [PDF]
Abdel Karim Sermé, Aboubacar Coulibaly, Koumpielimé Sosthène Somda, Dimitri Darankoum, Delphine Napon/Zongo, Soré Moussa Zanga, Hector Godonou, Kadidiatou Cissé, Issiaka Ouedraogo, Ali Ouedraogo
Open Journal of Gastroenterology (OJGas) , 2017, DOI: 10.4236/ojgas.2017.71001
Abstract: Uterine perforation is a serious complication after insertion of an intrauterine device (IUD). We report the case of a 34-year-old woman receiving in consultation for abdominal pain. In the interrogation there was a notion of IUD insertion for about a week. The gynecological examination did not find the thread of IUD and the ultrasound performed did not visualize an IUD. Radiography of the abdomen without preparation highlighted a compatible intrapelvic foreign thing like an IUD. The diagnosis of pelvic inflammatory disease by uterine perforation by an IUD was thus retained. We suggest in case of suspicion of uterine radio paque IUD perforation achieving radiography when the abdominal pelvic ultrasound is normal.
The Determinants of Fatal Outcomes during Severe Malaria in Children at the HKM University Teaching Hospital of Cotonou-Benin  [PDF]
Godonou Gratien Sagbo, Florence Alihonou, Marouf Jules Alao, Yévèdo Tohodjèdé, Lutécia Zohoun, Gilles Bognon, Joseph Agossou, Alphonse Noudamadjo, A?da Orou-Guidou
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.74028
Abstract: Introduction: Malaria particularly affects children in sub-Saharan African countries. This study aimed to investigate the factors associated with death in cases of severe childhood malaria to better understand the determinants of death in these children. Patients and Methods: This cohort, descriptive and analytical study was conducted from April 1 to August 15, 2015, at the CNHU-HKM pediatric clinic in Cotonou. Recruitment was exhaustive for all patients under 15 years of age who were admitted for severe malaria, as confirmed by thick smear microscopy. Results: Among the 1774 admitted patients, 449 had severe malaria caused by Plasmodium falciparum (i.e., a hospital frequency of 25.31%). The age group most affected consisted of children younger than 60 months of age (73%); female predominance was noted. The lethality rate of malaria was 13.1% (n = 59). The factors associated with death were coma (p = 0.032), poor convulsive status epilepticus (p = 0.08) and bacterial co-infection by gram negative bacteria (p = 0.021) with respectively correlations coefficient of 0.003, 3.940 and 2.424. Conclusion: Reduction of the malaria mortality rates in Benin
Contribution of the Urine Dipstick to Urinary Tract Infection Diagnosis among Children in Two Hospitals in Cotonou-Benin  [PDF]
Godonou Gratien Sagbo, Fredias Sogbo, Honorat Francis Lalya, Joseph Agossou, Yevedo Tohodjèdé, Florence Alihonou, Gilles Bognon, Diane Ahinonhossou, Afolabi Dissou, Blaise Ayivi
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.74031
Abstract: Introduction: Urinary tract infections are a daily concern in pediatric nephrology with long-term risks for high blood pressure and renal failure. The purpose of this study was to determine the contribution of a urine dipstick (UD) to the diagnosis of urinary infections among children at the CNHU-HKM and the Lagoon Mother and Child University Teaching Hospital (CHU-MEL) of Cotonou. Patients and Methods: This study is a cohort, descriptive and analytical study focused on children with suspected urinary infections in the pediatric units of the CNHU-HKM and CHU-MEL of Cotonou from March 25 to August 25, 2015. Results: Two hundred and four children out of a total of 5125 admitted children (4%) presented with at least one clinical sign of a urinary tract infection. Children under 36 months of age were predominant (41%). The main clinical signs of urinary infections were fever (60.8%) and urinary disorders (38.2%). The urinary dipstick test was positive in 145 children (71.2%). A urinary tract infection was confirmed by urine culture in 38 children (18.6%). In cases with leucocyturia- and nitrituria-positive urine dipstick tests, the sensitivity was estimated to be 13.2%, and the specificity was 95.2%, with a negative predictive value (NPV) of 82.8%. Only when the leucocyturia test was positive, the sensitivity was 76.3%, and the specificity was 31.9%. When the leucocyturia test was negative, the specificity was estimated to be 94%, and the sensitivity was 83% in the nitrituria-positive cases and 15.8% in the nitrituria-negative cases. The main isolated pathogens were Escherichia coli
Frequency of Hypovitaminosis D in 6 - 59 Month Children with Severe Malaria in the Pediatrics Unit of the Teaching Hospital of Parakou (CHUD/BA) in Benin in 2016  [PDF]
Alphonse Noudamadjo, Julien Didier Adédémy, Joseph Agossou, Gratien Godonou Sagbo, Falilatou Agbeille, Gérard Kpanidja, Jacques Assoklé, Simon Akpona
Open Journal of Pediatrics (OJPed) , 2018, DOI: 10.4236/ojped.2018.81009
Abstract: Introduction: Vitamin D’s action outside of bone, especially on immunity, is widely reported in the international scientific literature over the last years. Objective: Calculate the frequency of hypovitaminosis D in children aged 6 to 59 months suffering from severe malaria in the CHUD-P pediatric unit in 2016. Setting and Methods: This research work is a cross-sectional study with descriptive and analytical purposes. Data gathering was prospective. The study involved children aged 6 to 59 months hospitalized for severe malaria in the CHUD-P pediatric unit. The said children were HIV-uninfected, eutrophic and had not received vitamin D supplementation during the last 6 months. Vitamin D dose was measured using the High Performance Liquid Chromatography (HPLC) technique. Results: A total of 80 subjects were involved in the survey. Mean age was 26.08 months, sex ratio was 0.8 and average weight was 10.80 kg. Hypovitaminosis D frequency was 83.8% (67 cases out of 80 children investigated during the survey) with an average plasma concentration of vitamin D estimated at 21.57 ng/ml ± 7.34 with two extremes (11.24 - 42.32) ng/ml. The minimum parasitaemia was 202 P/μl and the maximum was 580,000 P/μl. Conclusion: Hypovitaminosis D is common in children suffering from
Serotypes of Bacteria Encountered in Childhood Purulent Meningitis in Children in Parakou (Benin) in 2011  [PDF]
Joseph Agossou, Julien Didier Adédémy, Alphonse Noudamadjo, Mahougnon Rachelle Mariette Houessou, Pierre Tsawlassou, Rolande Assogba, Godonou Gracien Sagbo, Honorat Francis Lalya, Maroufou Jules Alao, Honoré Bankolé, F. Hounsou, Rock Aristide Sossou, José Biey, Martin Antonio, Claire Oluwalana, Jarju Sheikh, Sikiratou Adéothy-Koumakpa?, Ayélèrou Simon Akpona, Blaise Ayivi
Open Journal of Pediatrics (OJPed) , 2016, DOI: 10.4236/ojped.2016.61017
Abstract: Introduction: In the North-Benin, there are three agents causing pediatric purulent meningitis outside the neonatal period. These are: Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b. The aim of this research work was to investigate bacteria serotypes that caused childhood purulent meningitis in the pediatric unit of the Borgou à Regional University Teaching Hospital (CHUD-Borgou) located in Parakou (North-Benin). Patients and Methods: Through a prospective and descriptive study centered on children aged 0 to 5 years old suspected of meningitis and hospitalized, the cerebrospinal fluid (CSF) samples of those children were analyzed at the WHO reference laboratory in Banjul for serotyping by real time polymerase chain reaction (RT/PCR). Results: Among the 1396 children hospitalized during that period, 366 were suspected of meningitis and had benefitted from lumbar puncture. Among those 366 suspected cases, 51 cases of purulent meningitis were confirmed after CSF cytobacteriological and biochemical test at the CHUD-Borgou laboratory. Among 51 CSF samples in which purulent meningitis was confirmed, 44 were sent to Banjul. In addition, 310 CSF samples from non-confirmed cases of meningitis were also sent to Banjul. In the whole set of samples sent for real time PCR, 151 cases of Streptococcus pneumoniae (42.7%) were found, 5 cases of Neisseria meningitidis (1.4%) and 1 case of Haemophilus influenzae (0.3%) were also encountered. As regards Streptococcus pneumonia, the serotypes encountered were: 1, 3, 4, 5, 7F, 8, 9V, 9V/9A, 9N/9L, 14, 18C, 19A, 23F, 33F as well as non typed and non typable serotypes. As for Neisseria meningitidis, only serogroup A was found in it. For Haemophilus influenzae, only serotype b was identified. Conclusion: Four non vaccine serotypes (8, 9V/9A, 9N/9L and 33F), non typed and non typable serotypes which are not covered by 13-valent pneumococcal conjugate vaccine (PCV 13) were identified. This highlights the need to enhance surveillance of pediatric purulent meningitis and serotyping by RT/PCR of all CSF samples in order to adapt if necessary future new pneumococcal vaccines to circulating non vaccine serotypes.
Euler-Lagrange Elasticity: Differential Equations for Elasticity without Stress or Strain  [PDF]
H. H. Hardy
Journal of Applied Mathematics and Physics (JAMP) , 2013, DOI: 10.4236/jamp.2013.17004

Differential equations to describe elasticity are derived without the use of stress or strain. The points within the body are the independent parameters instead of strain and surface forces replace stress tensors. These differential equations are a continuous analytical model that can then be solved using any of the standard techniques of differential equations. Although the equations do not require the definition stress or strain, these quantities can be calculated as dependent parameters. This approach to elasticity is simple, which avoids the need for multiple definitions of stress and strain, and provides a simple experimental procedure to find scalar representations of material properties in terms of the energy of deformation. The derived differential equations describe both infinitesimal and finite deformations.

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