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Search Results: 1 - 10 of 421576 matches for " Gustavo M.;Lima "
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Thermal effusivity estimation of polymers in time domain
Lima, Gustavo Meirelles;Lima e Silva, Sandro M. M. de;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2011, DOI: 10.1590/S1678-58782011000400002
Abstract: an accurate knowledge of thermophysical properties is very important, for example, to optimize the engineering design and the development of new materials for many applications. thermal effusivity is a thermal property which presents an increasing importance in heat conduction problems. this property indicates the amount of thermal energy that a material is able to absorb. the estimation can be done by simulating a transient heat transfer model. in this case a one-dimensional semi-infinite thermal model is used. a resistance heater in contact with the sample generates a heat pulse. variations of temperature and heat flux are measured simultaneously on the top surface of the sample. in this work, thermal effusivity is estimated in time domain through the minimization of the objective function, defined as the square difference between experimental and theoretical temperatures. the golden section technique is used for minimizing this objective function. a sensitivity analysis and a comparison between the semi-infinite and the finite models were also done to define the number of points to be used in the estimation. measurements were carried out with three different polymers: polymethyl methacrylate, polyvinyl chloride and polyethylene. in all cases studied the results are in good agreement with literature. in addition, an uncertainty analysis is also presented.
Asociación de la insulina y el factor de crecimiento semejante a la insulina tipo 1 (IGF-1) en el cáncer de mama
Marcos M Lima,Edwin Velásquez,Gustavo Unshelm,Torres Christopher
Gaceta Médica de Caracas , 2009,
Abstract: Con el objetivo de evaluar la asociación de la insulina y el factor de crecimiento insulino similar tipo 1 (IGF-1) en pacientes con cáncer de mama, se eligió una muestra de 15 pacientes con diagnóstico histopatológico de cáncer de mama durante el período enero-agosto de 2008, y se determinaron los niveles de glicemia en ayunas, insulina basal e IGF-1. Se evaluó el grado de insulino-sensibilidad mediante el método HOMA en esta muestra, comparándose posteriormente con pacientes sin cáncer y de edades similares. Encontramos que la concentración plasmática de insulina en las pacientes con cáncer fue de 11,53 ± 1,91 μU/ mL; mientras que los controles presentaron 5,1 ± 0,98 μU/ mL, lo cual resultó estadísticamente significativo (P<0,01). Además, las pacientes con cáncer de mama exhibieron glicemia de 108,57 ± 12,33 mg/dL, en comparación con los controles quienes obtuvieron 80,92 ± 1,40 mg/dL. Con estos resultados se calculó el HOMA, obteniendo valores de 3,15 y 1,00 respectivamente. Adicionalmente, al determinar IGF-1 observamos niveles de 219,64 ± 17,03 ng/mL en las pacientes con cáncer y de 178,47 ± 12,78 ng/mL en controles. Se concluye que las pacientes con cáncer de mama presentan el fenómeno de resistencia a la insulina, el cual de manera sinérgica con el IGF-1 promueve la proliferación y diferenciación de células mamarias. Samples from 15 patients who had been diagnosed with breast cancer during January-August 2008 were assayed for the purpose of evaluating the association of insulin and insulin-like growth factor-1 (IGF-1) in women with this type of cancer. Assays were performed to measure fasting blood glucose, basal insulin, and IGF-1. A homeostatic model assessment test (HOMA) was also performed to assess insulin sensitivity, and the results were matched against those of healthy women of the same age group. Insulin plasma concentration in the former group was 11.53 ± 1.91 μU/ mL whereas that of the control group was 5.1±0.98 μU/mL, a statistically significant finding. (P<0.01). In addition, the glucose level in the sick women was 108.57±12.33 mg/dL as compared to 80.92±1.40 mg/dL in those without cancer. HOMA was 3.15 and 1.00, and IGF.1 levels were 219.64±17.03 ng/mL and 178.47±12.78 ng/mL for sick and healthy women, respectively. It is thus concluded that women with cancer develop insulin resistance, which in synergy with IGF-1, promotes breast cell proliferation and differentiation.
Formula??o das dietas, desempenho e qualidade da carca?a, produ??o e composi??o de dejetos de suínos
Nones, Kátia;Lima, Gustavo J.M.M. de;Bellaver, Cláudio;Rutz, Fernando;
Scientia Agricola , 2002, DOI: 10.1590/S0103-90162002000400003
Abstract: the efficiency with which animals utilize each ingredient in the diet is related to the way by which information on nutrient composition and digestibility is used. swine feed formulation based on crude protein may result in an imbalance of aminoacids, which in turn results in the deamination of aminoacids. nitrogen may be used in the synthesis of new compounds or just excreted through urine, becoming a loss in efficiency and increasing pollution potential. two studies were carried out to evaluate the effects of types of feed formulation in growing and finishing swine. growing and finishing diets were: 1) formulation based on crude protein and total aminoacids, according to nrc; 2) total lysine (lys) levels 15% above those of diet 1; 3) protein levels similar to diet 2, but meeting the ideal protein level; 4) similar to diet 3 with 15% more digestible lys. swine fed diets 2 and 4 showed higher daily weight gain. backfat, longissimus dorsi area and lean tissue were not affected by treatments. animals fed diets with higher protein levels showed higher fecal excretion. animals fed diets with 15% more lys (diets 2 and 4) showed lower fecal nitrogen excretion without any effect on the excretion of this element through urine.
Formula o das dietas, desempenho e qualidade da carca a, produ o e composi o de dejetos de suínos
Nones Kátia,Lima Gustavo J.M.M. de,Bellaver Cláudio,Rutz Fernando
Scientia Agricola , 2002,
Abstract: A eficiência de utiliza o dos alimentos pelos animais pode ser influenciada pela maneira como as informa es de composi o e digestibilidade dos nutrientes s o utilizadas. A formula o de ra es para suínos baseada no conceito de proteína bruta pode apresentar níveis de aminoácidos desbalanceados ocasionando a desamina o dos aminoácidos em excesso. O nitrogênio disponível pode ser utilizado na síntese de outros compostos ou simplesmente excretado, o que significa perda de eficiência no processo e aumento da capacidade poluente dos dejetos produzidos. Assim, foram realizados dois experimentos para estudar os efeitos do uso de formula o de dietas para suínos em crescimento e termina o. As dietas foram: 1) formula o baseada nas exigências de proteína bruta e aminoácidos totais do NRC; 2) formula o com níveis de lisina (Lys) total 15% superiores ao da dieta 1; 3) formula o com teor de proteína semelhante ao da dieta 2 mas atendendo a proteína ideal; 4) formula o atendendo a proteína ideal proposta por Baker (1997), com 15% mais Lys digestível mantendo-se o mesmo teor de proteína. Os animais que receberam as dietas 2 e 4 apresentaram maior ganho de peso diário. Para espessura de toucinho, profundidade de lombo e porcentagem de carne n o houve efeito de tratamento. As dietas com níveis de proteína mais elevados proporcionaram maior excre o de fezes. Os animais que receberam as dietas formuladas com 15% mais Lys (dietas 2 e 4) apresentaram menor excre o de nitrogênio nas fezes, sem afetar a excre o deste na urina.
IgG Fc Receptors Provide an Alternative Infection Route for Murine Gamma-Herpesvirus-68
Gustavo T. Rosa, Laurent Gillet, Christopher M. Smith, Brigitte D. de Lima, Philip G. Stevenson
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000560
Abstract: Background Herpesviruses can be neutralized in vitro but remain infectious in immune hosts. One difference between these settings is the availability of immunoglobulin Fc receptors. The question therefore arises whether a herpesvirus exposed to apparently neutralizing antibody can still infect Fc receptor+ cells. Principal Findings Immune sera blocked murine gamma-herpesvirus-68 (MHV-68) infection of fibroblasts, but failed to block and even enhanced its infection of macrophages and dendritic cells. Viral glycoprotein-specific monoclonal antibodies also enhanced infection. MHV-68 appeared to be predominantly latent in macrophages regardless of whether Fc receptors were engaged, but the infection was not abortive and new virus production soon overwhelmed infected cultures. Lytically infected macrophages down-regulated MHC class I-restricted antigen presentation, endocytosis and their response to LPS. Conclusions IgG Fc receptors limit the neutralization of gamma-herpesviruses such as MHV-68.
Asociación de la insulina y el factor de crecimiento semejante a la insulina tipo 1 (IGF-1) en el cáncer de mama
Lima,Marcos M; Velásquez,Edwin; Unshelm,Gustavo; Christopher,Torres; Francisco,Rosa; Lanza,Pedro;
Gaceta Médica de Caracas , 2009,
Abstract: samples from 15 patients who had been diagnosed with breast cancer during january-august 2008 were assayed for the purpose of evaluating the association of insulin and insulin-like growth factor-1 (igf-1) in women with this type of cancer. assays were performed to measure fasting blood glucose, basal insulin, and igf-1. a homeostatic model assessment test (homa) was also performed to assess insulin sensitivity, and the results were matched against those of healthy women of the same age group. insulin plasma concentration in the former group was 11.53 ± 1.91 μu/ ml whereas that of the control group was 5.1±0.98 μu/ml, a statistically significant finding. (p<0.01). in addition, the glucose level in the sick women was 108.57±12.33 mg/dl as compared to 80.92±1.40 mg/dl in those without cancer. homa was 3.15 and 1.00, and igf.1 levels were 219.64±17.03 ng/ml and 178.47±12.78 ng/ml for sick and healthy women, respectively. it is thus concluded that women with cancer develop insulin resistance, which in synergy with igf-1, promotes breast cell proliferation and differentiation.
Interpretando o algoritmo de Deutsch no interfer?metro de Mach-Zehnder
Cabral, Gustavo Eulalio M.;Lima, Aércio Ferreira de;Lula Jr., Bernardo;
Revista Brasileira de Ensino de Física , 2004, DOI: 10.1590/S0102-47442004000200005
Abstract: quantum computation is a relatively new research area, which has been in development in the past 20 years, and which makes use of the fundamentals of computer science and quantum physics. two are the quantum phenomena in which quantum computation is based: superposition and interference. in this work, we will highlight the role of interference in the solution of the problem proposed by deutsch, which consists of knowing if a given function is constant or balanced, executing the function only once. figuratively, this is the same as knowing if a coin is honest or faked (two equal faces) looking only once. deutsch's solution (algorithm) is frequently explained in an abstract manner and with the help of circuits. however, although efficient to express the "logics" and facilitate the development of quantum algorithms, that approach does not make it clear and easy to realize the underlying physical phenomena. in this work, we show, in a didatic way, how the mach-zehnder interferometer implements deutsch's algorithm, thus highlighting the importance of interference in the realization of quantum algorithms.
Efeito da restri??o alimentar como redutor do poder poluente dos dejetos de suínos
Marcato, Simara Márcia;Lima, Gustavo Júlio Mello Monteiro de;
Revista Brasileira de Zootecnia , 2005, DOI: 10.1590/S1516-35982005000300017
Abstract: with the objective to evaluate the effect of feed restriction on fecal mineral content of finishing swine, forty-eight barrows, with initial weight of 41.92 ± 0.27 kg were assigned to a randomized experimental block design. treatments were: t1=ad libitum feeding; t2=95% t1 feed intake; and t3 = 90% t1 feed intake and 16 replications. animals were kept during 21 days in adaptation period to the treatments in collective pens and metabolism cages. urine and fecal collection was performed during two days, using 20 g of colored plastic particles as fecal markers. there was a reduction of 8.54% in the daily feed consumption of the diet in t3 animals, causing a decrease close to 9.65% in fecal mineral content, as compared to ad libitum consumption (t1). all macro minerals, except for magnesium, showed significant reduction in the fecal content with the increase of feed restriction. calcium and potassium fecal content represented about 29% of the excreted mineral matter of the animals and both were significantly reduced with the use of feed restriction. for all micro minerals, the relations between excreted amount and consumed amount were equal or higher than 86.60%, indicating that the animals showed a low retention efficiency of these nutrients. in conclusion, feed restriction in finishing phase of swine cause reduction in the amount of dry matter and almost all minerals excreted. therefore, the use of this practice can contribute to reduce pollution problems of swine manure.
Assessment of Thromboembolism After the Cox-Maze Procedure for Chronic Atrial Fibrillation Secondary to Mitral Valve Lesion
Kalil Renato A. K.,Nesralla Paula L. M.,Lima Gustavo G.,Leiria Tiago L.
Arquivos Brasileiros de Cardiologia , 2002,
Abstract:
Técnica cirúrgica simplificada pode ser eficaz no tratamento da fibrila o atrial cr nica secundária a les o valvar mitral?
KALIL Renato A. K.,LIMA Gustavo G.,ABRAH?O Rogério,STüRMER Márcio L.
Revista Brasileira de Cirurgia Cardiovascular , 2000,
Abstract: INTRODU O: Fibrila o atrial tem sido tratada pelo procedimento do Labirinto (Cox) e suas modifica es. Há, no entanto, evidências de que o isolamento dos óstios das veias pulmonares ou exclus o do átrio esquerdo poderia ser eficaz para este fim. CASUíSTICA E MéTODOS: Avaliamos os resultados iniciais da técnica simplificada de isolamento cirúrgico dos óstios das veias pulmonares para tratar fibrila o atrial cr nica em pacientes operados por les o valvar mitral. Foram tratados 7 pacientes por esta técnica (grupo IVP) e comparados com série prévia de 57 casos submetidos a cirurgia do Labirinto (Cox 3). RESULTADOS: A idade média foi de 49±8 anos vs 49±11 anos, (IVP vs. Cox3), sendo 71% e 72% (IVP vs. Cox 3) do sexo feminino. Dimens es do átrio esquerdo 5,5±0,7 cm vs. 6,0±1,1 cm (IVP vs. Cox 3). Fra o de eje o ventricular 63±10% vs. 64±6% (IVP vs. Cox 3). Tempo CEC 91±33 min vs. 104±29 min (IVP vs. Cox 3). Tempo de isquemia71±23 min vs. 83±26 min (IVP vs. Cox 3). Ritmo pós-operátório sinusal/atrial n(%): 6(86) vs. 46(80) (IVP vs. Cox 3). Ritmo marcapasso n(%):1 (14) vs. 4 (7) (IVP vs. Cox 3). Fibrila o atrial n(%): 0 vs. 7 (13) (IVP vs. Cox 3). CONCLUS ES: Resultados iniciais mostram revers o a ritmo sinusal na maioria dos casos em ambos procedimentos e manuten o do ritmo a longo prazo. Foi iniciado estudo prospectivo randomizado para avaliar o IVP comparativamente ao procedimento Cox 3.
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