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Search Results: 1 - 10 of 23627 matches for " Guoqiang He "
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Screening of Microalgae for Biodiesel Feedstock  [PDF]
Xi Chen, Guoqiang He, Zhiping Deng, Nan Wang, Wei Jiang, Sanfeng Chen
Advances in Microbiology (AiM) , 2014, DOI: 10.4236/aim.2014.47044

Three heterotrophic microalgae identified as Scenedesmus sp. Y5, Scenedesmus sp. Y7 and Chorellasp. Y9 were isolated and screened from natural water based on biomass yield and lipid productivity. Fatty acids’ composition analysis showed that both Y5 and Y7 mainly contained C16:0, C18:1 (n - 9), C18:2 (n - 6) and C18:3 (n - 3) and Y9 mainly contained C16:0, C18:0 and C18:2 (n - 6), suggesting that these microalgae can be ideal feedstock for biodiesel. Considering the specific growth rate and lipid productivity, the culture conditions were optimized for Scenedesmus sp. Y5, Scenedesmus sp. Y7 and Chorellasp. Y9. Based on the optimization of cultural conditions, all of these three microalgae were tested in fed-batch fermentation, and their biomass productivities were 4.960 g·L-1·d-1, 5.907 g·L-1·d-1 and 4.038 g·L-1

Differential Expression of Brain Cannabinoid Receptors between Repeatedly Stressed Males and Females may Play a Role in Age and Gender-Related Difference in Traumatic Brain Injury: Implications from Animal Studies
Guoqiang Xing,Min Jia,He Li
Frontiers in Neurology , 2014, DOI: 10.3389/fneur.2014.00161
Abstract: Inconsistent gender differences in the outcome of TBI have been reported. The mechanism is unknown. In a recent male animal study, repeated stress followed by TBI had synergistic effects on brain gene expression and caused greater behavioral deficits. Because females are more likely to develop anxiety after stress and because anxiety is mediated by cannabinoid receptors (CBRs) (CB1 and CB2), there is a need to compare CB1 and CB2 expression in stressed males and females. CB1 and CB2 mRNA expression was determined in the amygdala, hippocampus, prefrontal cortex (PFC), and hypothalamus of adolescent male and female rats after 3 days of repeated tail-shock stress using qPCR. PFC CB1 and CB2 protein levels were determined using Western blot techniques. Both gender and stress had significant effects on brain CB1 mRNA expression levels. Overall, females showed significantly higher CB1 and CB2 mRNA levels in all brain regions than males (p < 0.01). Repeated stress reduced CB1 mRNA levels in the amygdala, hippocampus, and PFC (p < 0.01, each). A gender × stress interaction was found in CB1 mRNA level in the hippocampus (p < 0.05), hypothalamus (p < 0.01), and PFC (p < 0.01). Within-sex one-way ANOVA analysis showed decreased CB1 mRNA in the hippocampus, hypothalamus, and PFC of stressed females (p < 0.01, each) but increased CB1 mRNA levels in the hypothalamus of stressed males (p < 01). There was a gender and stress interaction in prefrontal CB1 receptor protein levels (p < 0.05), which were decreased in stressed females only (p < 0.05). Prefrontal CB2 protein levels were decreased in both male and female animals after repeated stress (p < 0.05, each). High basal levels of CBR expression in young na?ve females could protect against TBI damage whereas stress-induced CBR deficits could predict a poor outcome of TBI in repeatedly stressed females. Further animal studies could help evaluate this possibility.
Prognostic value of HMGB1 overexpression in resectable gastric adenocarcinomas
Guoqiang Bao, Qing Qiao, Huadong Zhao, Xianli He
World Journal of Surgical Oncology , 2010, DOI: 10.1186/1477-7819-8-52
Abstract: 76 gastric adenocarcinomas surgically removed entered the study. The immunohistochemical staining was used to assess HMGB1 expression through tissue microarray procedure. The clinicopathologic characteristics of all patients were recorded, and the regular follow-up was made for all patients.Almost all the gastric adenocarcinomas showed HMGB1 positive staining mainly in the nucleus, and the overexpression of HMGB1 was found in cancerous tissues with higher strong reactivity rate, compared with non-cancerous tissues (total expression score ≥ 9, 42.0% vs. 9.0%, P < 0.001). Survival analysis revealed that tumor stage negatively correlated with cancer-free survival (P = 0.022). Furthermore, HMGB1 overexpression positively associated with cancer-free survival of resectable gastric adenocarcinomas (P = 0.023).The overexpression of HMGB1 protein indicates that HMGB1 may play a role in the tumorigenesis of gastric adenocarcinomas. And the overexpression of HMGB1 may be a marker of good prognosis of gastric adenocarcinoma given curative resection combined with adjuvant chemotherapy.Gastric cancer (GC) is the second most common cause of cancer-related death in the world. Many Asian countries, including China, have very high rates of GC. For patients in advanced stages, the five-year survival rate is only about 20 percent. There are many factors that limit the prognosis of the disease. High mobility group box l (HMGB1), a nuclear DNA-binding protein, originally described as a nuclear protein that binds to and modifies DNA, stabilizes the structure and function of chromatin and regulates gene transcription. It has been realized that HMGB1 can act either as a DNA binding protein or extracellularly as a cytokine-like danger signal, which is either actively secreted or passively released by necrotic cells[1]. Now HMGB1 is regarded as a central mediator of inflammation by acting as a cytokine, which has been reported as a "late" proinflammatory mediator in sepsis [2,3].HMGB1 plays a
In situ FTIR spectroscopic studies of CO adsorption on electrodes of nanometer-thin layer of Pt-Ru and Pt-Pd surface alloys
Guoqiang Lu,Lirong Cai,Shigang Sun,Junxiang He
Chinese Science Bulletin , 1999, DOI: 10.1007/BF03183565
Abstract: CO adsorption on nanometer-thin layer of surface alloys of Pt-Ru and Pt-Pd prepared by electrochemical codeposition has been studied usingin situ FTIR spectroscopy. Abnormal infrared effects (AIREs) that consist of the enhancement of IR absorption by adsorbed CO on different surface sites and the inversion of IR band direction have been observed on the thin-layer prepared. The results also demonstrate the considerable significance of Pt-Ru and Pt-Pd surface alloys in electrocatalysis applications.
Numerical Implementation of Nonlinear Implicit Iterative Method for Solving Ill-posed Problems
Jianjun Liu,Zhe Wang,Guoqiang He,Chuangang Kang
International Journal of Information Technology and Computer Science , 2011,
Abstract: Many nonlinear regularization methods may converge to local minima in numerical implementation for the complexity of nonlinear operator. Under some not very strict assumptions, we implement our proposed nonlinear implicit iterative method and have a global convergence results. Using the convexity property of the modified Tikhonov functional, it combines nonlinear implicit iterative method with a gradient method for solving ill-posed problems. Finally we present two numerical results for integral equation and parameter identification.
A Freight Mode Choice Analysis Using a Binary Logit Model and GIS: The Case of Cereal Grains Transportation in the United States  [PDF]
Guoqiang Shen, Jiahui Wang
Journal of Transportation Technologies (JTTs) , 2012, DOI: 10.4236/jtts.2012.22019
Abstract: Mode choice is important in shipping commodities efficiently. This paper develops a binary logit model and a regression model to study the cereal grains movement by truck and rail in the United States using the publically available Freight Analysis Framework (FAF2.2) database and U.S. highway and networks and TransCAD, a geographic information system with strong transportation modeling capabilities. The binary logit model and the regression model both use the same set of generic variables, including mode split probability, commodity weight, value, network travel time, and fuel cost. The results show that both the binary logit and regression models perform well for cereal grains transportation in the United States, with the binary logit model yielding overall better estimates with respect to the observed truck and rail mode splits. The two models can be used to study other commodities between two modes and may produce better results if more mode specific variables are used.
Study on the Performance Optimization of Knitted Fabric Anti-Roll by Tissue Structure  [PDF]
Guoqiang Chen, Yanan Zhu
Journal of Materials Science and Chemical Engineering (MSCE) , 2018, DOI: 10.4236/msce.2018.64001
Will use the same number of positive and negative coil longitudinal organization of fabric is ta edge sex used in the work of the organization to warp fabric edge sex, between restrained knitting principle, design a kind of weft basketwork weaving method, especially in weft knitting machine woven from has the edge of weft knitted fabric performance weaving method. In order to overcome the existing technology aims to make weft basketwork structure of a single organization, edge sex is bad, or can’t produce rich weft knitted fabric appearance of shortage, provide a resistance to edge weft knitted fabric weaving method.
Investigation of Range Profiles from a Simplified Ship on Rough Sea Surface and Its Multipath Imaging Mechanisms
Siyuan He,Fan Zhang,Weidong Hu,Lei Zhuang,Xingbin Ye,Guoqiang Zhu
International Journal of Antennas and Propagation , 2012, DOI: 10.1155/2012/894198
Abstract: The range profiles of a two-dimension (2 D) perfect electric conductor (PEC) ship on a wind-driven rough sea surface are derived by performing an inverse discrete Fourier transform (IDFT) on the wide band backscattered field. The rough sea surface is assuming to be a PEC surface. The back scattered field is computed based on EM numerical simulation when the frequencies are sampled between 100 MHz and 700 MHz. Considering the strong coupling interactions between the ship and sea, the complicated multipath effect to the range profile characteristics is fully analyzed based on the multipath imaging mechanisms. The coupling mechanisms could be explained by means of ray theory prediction and numerical extraction of the coupling currents. The comparison of the range profile locations between ray theory prediction and surface current simulation is implemented and analyzed in this paper. Finally, the influence of different sea states on the radar target signatures has been examined and discussed.
High γ-Radiation Sensitivity Is Associated with Increased Gastric Cancer Risk in a Chinese Han Population: A Case-Control Analysis
Honglin Dong, Xiaowei Jin, Jie Hu, Haifeng Li, Xianli He, Xiaonan Liu, Guoqiang Bao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0043625
Abstract: Hypersensitivity to radiation exposure has been suggested to be a risk factor for the development of several malignancies, but not including gastric cancer. In this case-control study, radiation sensitivity as measured by chromatid breaks per cell (b/c) was examined in cultured peripheral blood lymphocytes (PBLs) from 517 patients with gastric cancer and 525 healthy controls. Our results showed that b/c values were significantly higher in cases than in controls (Mean [SD], 0.47 [0.20] vs. 0.34 [0.17]; P<0.001). Using the 50th percentile value for controls (0.34 b/c) as the cutoff point, unconditional logistic regression analysis revealed that γ–radiation-sensitive individuals were at significantly higher risk for gastric cancer (adjusted odds ratio [OR] 2.01, 95% confidence interval [CI] 1.49–3.13). Quartile stratification analysis indicated a dose-response relationship between γ-radiation sensitivity and gastric cancer risk (P for trend <0.001). When using the subjects in first quartile of b/c values as reference, the adjusted ORs and corresponding CIs for the subjects in second, third, and fourth quartiles were 1.48 (0.91–2.17), 2.42 (1.76–3.64), and 3.40 (2.11–5.29), respectively. The γ-radiation sensitivity was related to age and smoking status. In addition, a clear joint effect on cancer risk was found between γ-Radiation sensitivity and smoking status. The risk for ever smokers with high sensitivity was higher than those for never smokers with high sensitivity and ever smokers with low sensitivity (OR [CI], 4.67 [2.31–6.07] vs. 2.14 [1.40–3.06] vs. 2.42 [1.57–3.95], respectively). No significant interaction was found between both factors (P for interaction = 0.42). We conclude that chromatid radiosensitivity is associated with gastric cancer susceptibility in a Chinese population.
Irradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population
Xianli He, Qing Qiao, Naijian Ge, Jing Nan, Shuqun Shen, Zizhong Wang, Yefa Yang, Guoqiang Bao
BMC Cancer , 2010, DOI: 10.1186/1471-2407-10-312
Abstract: To explore this hypothesis, 246 GC cases and 246 matched controls were recruited in our case-control study. TRAP-ELISA was used to assess the levels of telomerase activity at baseline and after γ-radiation and the γ-radiation-induced telomerase activity (defined as after γ-irradiation/baseline) in cultured peripheral blood lymphocytes (PBLs).Our data showed that there was no significant difference for the baseline telomerase activity between GC cases and controls (10.17 ± 7.21 vs. 11.02 ± 8.03, p = 0.168). However, after γ-radiation treatment, γ-radiation-induced telomerase activity was significantly higher in the cases than in the controls (1.51 ± 0.93 vs. 1.22 ± 0.66, p < 0.001). Using the median value of γ-radiation-induced telomerase activity in the controls as a cutoff point, we observed that high γ-radiation-induced telomerase activity was associated with a significantly increased GC risk (adjusted odds ratio, 2.45; 95% confidence interval, 1.83-3.18). Moreover, a dose response association was noted between γ-radiation-induced telomerase activity and GC risk. Age, but not sex, smoking and drinking status seem to have a modulating effect on the γ-radiation-induced telomerase activities in both cases and controls.Overall, our findings for the first time suggest that the increased γ-radiation-induced telomerase activity in PBLs might be associated with elevated GC risk. Further confirmation of this association using a prospective study design is warranted.Telomerase is a specialized ribonucleoprotein consisting of a RNA subunit (telomerase RNA [TR]) and a rate-limiting catalytic protein subunit (telomerase reverse transcriptase [TERT])[1]. A well-established function of telomerase is to synthesize telomeric repeats onto chromosomal ends and thus be responsible for the telomere maintenance [2]. In most normal human somatic cells, telomerase activity is not detectable or at very low level[3]; however, telomerase activity has been confirmed in approximately 85% of p
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