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Search Results: 1 - 10 of 7179 matches for " Grace Irene Imbiríba; "
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Contribui??o preliminar aos tipos polínicos da Tribo Mutisieae (Compositae)
Pastana, Grace Irene Imbiríba;
Acta Botanica Brasilica , 1988, DOI: 10.1590/S0102-33061988000300006
Abstract: the present paper is a palynological study of the fourteen species of the tribe mutisieae, belong to the museum nacional herbary - rj (r). several aspects relating caracteristics of mutisieae pollen are treated such as polar and equatorial diameter, l. o.: table of statistical treatment and comparative diagrams are displayed.
Impact of Therapeutic Education on the Viral Load of HIV Infected Children and Adolescents on Antiretroviral Therapy at the Douala Laquintinie Hospital, Cameroon  [PDF]
Calixte Ida Penda, Anne-Cécile Zoung-Kanyi Bissek, Serge Clotaire Bilong, Loic-Ardin Boupda, Cécile Okala, Francis Atéba Ndongo, Grace Dallé Ngondi, Else C. Moukoko Eboumbou, Louis Richard Njock, Olivier Koki Ndombo
International Journal of Clinical Medicine (IJCM) , 2019, DOI: 10.4236/ijcm.2019.103011
Abstract: Introduction: One of the biggest challenges for HIV-infected adolescents on antiretroviral therapy (ART) is the long-term maintenance of viral suppression, which is the third 90% goal of UNAIDS. Therapeutic Education (TE), process of acquiring abilities and skills that help the patient to live optimally with his illness is one of the strategies that contribute to the achievement of viral suppression through the therapeutic adhesion contract and the follow-up of the patient. The aim of this study was to evaluate the impact of TE on the virologic response of children and adolescents aged 8 - 19 under ART and followed up at the Laquintinie Hospital of Douala (LHD). Method: A cross-sectional study was conducted at the Pediatric Unit of the HIV/AIDS Accredited Treatment Center (ATC) at LHD from February to May 2016. Children and adolescents aged 8 to 19 years on ART, followed in ATC/LHD whose parents had agreed to participate in the study, and who had achieved at least one viral load before and after initiation of TE, were recruited consecutively during routine medical follow-up. Data were collected from patients’ medical records and questionnaires administered to study participants. Results: A total of 198 children and adolescents were included in this study with an average age of 14 years (±3). In this study population, 86.1% of children aged 8 - 10 years had acquired knowledge of the importance of taking medications, 95.4% and 97.3% of adolescents aged 11 - 14 years and 15 - 19 years had knowledge of medication schedules respectively. Among children and adolescents with undetectable viral load prior to initiation of TE, 76.5% maintained an undetectable viral load after initiation of TE. In addition, 72.3% of those whose viral load was detectable before initiation of TE had acquired an undetectable or decreasing viral load after initiation of TE. The only exposure factor significantly associated with maintaining undetectable viral load after initiation of TE was having less than 10 TE sessions (p = 0.02). Conclusion: The virologic response appears to be better in subjects who acquire skills faster through TE and therefore require fewer learning sessions to adapt. In addition, TE effectively contributes to achieving the third 90% goal of UNAIDS.
Pyramidal and Granule Cells Distribution through Hippocampal Fields: An Index for Sensory Information Processing  [PDF]
Abdoulaye Ba
Journal of Behavioral and Brain Science (JBBS) , 2015, DOI: 10.4236/jbbs.2015.55018
Abstract: Background: This work aims at investigating the histology of hippocampus formation as structural model of information processing. The study addressed the question whether the pattern of cellular type distribution within hippocampal fields could be used as support of information processing in the hippocampus. Method: Pyramidal-shaped neurons presenting both cytoplasm and nucleus outlined clearly were measured systematically on brain slides, using a light microscope connected to a microcomputer equipped with a scanner software for measuring particles. Morphological types of cells were identified following class sizes and their distribution determined through hippocampal fields. Results: A battery of statistical tests: Sturges’ classification, class sizes distribution around overall mean, Bartlett’s sphericity test, principal components analysis (PCA) followed by correlations matrix analysis and ANOVA allowed two cellular groups to be identified in the hippocampus: large and small pyramidal-shaped cells. Conclusion: The results show that sensory information processing in the hippocampus could be built on two classes of pyramidal neurons that differed anatomically with probably different physiological functions. The study suggests combination ensembles clustering large and small pyramidal cells at different rates, as fundamental signaling units of the hippocampus.
Does Reactive Adaptation Exist? Using the Ecosystem Service Governance Approach to Evaluate Post-Drought Rural Food Security in Kenya  [PDF]
Grace W. Ngaruiya
Natural Resources (NR) , 2014, DOI: 10.4236/nr.2014.58037
Controversial climate change studies purport that predicted food insecurity and resource scarcity will intensify resource conflicts in developing nations. This belief is based on a prevalent assumption that African agricultural production systems are rigid and that their respective governments lack comprehensive adaptation ability. Therefore, I investigate whether and how effective post- drought adaptation activity is sustaining food production and livelihoods at Loitoktok district in Kenya. This study uses the theoretical three-step ecosystem service governance approach that analyzes both natural resources attributes and relational data. Results confirm a substantial decline in productivity and huge monetary losses in the agricultural sector of Loitoktok following the 2009 drought. Post-drought analysis reveals high diversification in crops and livestock that are drought-tolerant, fast maturing and high income generating such as camels, rabbits and dairy goats, horticultural and fruit production that sustain food security, income and local livelihoods. These reactive adaptation activities originate from an active public-private cooperation that promotes knowledge exchange among Loitoktok stakeholders. This cooperation is also seen in the efficient resource conflict resolution network. In conclusion, rural communities seem to be efficiently adapting to changing environmental conditions but require more financial and technical support from the government. Unfortunately, appraisal of national planned adaptation reveals effort-duplication that may divert much needed adaptation funds from being invested in research projects with multiple benefits to Kenyan food producers.
Testing the Effect of Soil Heterogeneity on Arbuscular Mycorrhiza Fungi (AMF) Contribution to Plant Productivity  [PDF]
Samuel Ayesu, Grace Gyabaah
Open Journal of Ecology (OJE) , 2014, DOI: 10.4236/oje.2014.46028

Most natural soils are heterogeneous and nutrient availability and soil structure change greatly over small distances. It is still unclear whether AMF are advantageous for plants under such heterogeneous soil conditions. The objective of this study was to determine whether diverse AMF community support host plant community productivity in heterogeneous soil. It was also tested whether soil heterogeneity affects plant productivity. This was carried out in a greenhouse experiment made up of two factors: soil heterogeneity and AMF richness. Soil heterogeneity was simulated by mixing three soil types (sand, field soil and organic soil) together (homogenous soil (HM)), mixing them partly (semi homogenous (SH)) or keeping the three soil types separate in three compartments within one pot (heterogeneous (HT)). AMF richness was simulated by adding no AMF, one of four different AMF species separately, or all four different AMF together. The pots were planted with a mixture of Trifolium pratense and Lolium multiflorum. There was no effect of soil heterogeneity on total plant biomass. However, the biomass of the individual plant species was greatly affected by soil heterogeneity with Lolium being the most abundant in the heterogeneous soil and Trifolium being the most abundant in the homogenous soil. Total plant biomass did not increase with AMF richness. Moreover, opposite to the hypothesis, AMF richness was not beneficial for plant productivity in a heterogenous soil environment. However, there were significant differences in plant biomass with different AMF treatments in the SH and HT treatment indicating that effects of AMF on plant productivity are influenced by soil type. These effects on yield and AMF reflect a combination of local responses to growing conditions. The results show that AMF influence on plant yield may not always be positive but is strongly dependent on ecological elasticity and environmental condition.

The Universality of the Portrayal of Gender in Television Advertisements: An East-West Comparison  [PDF]
Grace Lim, Adrian Furnham
Psychology (PSYCH) , 2016, DOI: 10.4236/psych.2016.713154
Abstract: This study compared portrayals of gender in Malaysian and British television advertisements regarding the portrayal of men and women across these two countries. A total of 236 advertisements were content analyzed for nine variables relating to the primary character of the advertisement. The findings provide evidence of gender stereotyping in both countries for types of products advertised, credibility and role of the primary characters. The results suggest that portrayals in British advertisements are similar to those in Malaysian advertisements despite the cultural gap. These findings are discussed in relation to implications and the limitations of the study are noted.
Virtues in Clinical Practice: Teaching Students about the Complexities and Depth of Professional Practice  [PDF]
Sandra Grace, Airdre Grant
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.813143
Abstract: This paper investigates the integration of virtues into teaching programs for allied health students. It explores the notion that practitioners’ effectiveness is enhanced when they practice virtues along with their technical expertise. These virtues include wisdom and love and they imbue the practitioner’s role with a meaning that extends beyond efficient diagnosis and competent case management. Practicing virtues can deepen the clinical relationship. Allied health students may feel cautious and uncertain about what it actually means to be a virtuous practitioner. Reflexive practice and dialogic encounters are presented as teaching activities that can cultivate virtuous practice.
Telomeres and Telomerase: Molecular Views and Perspectives  [PDF]
Kumar Arvind, Tony Grace
Advances in Aging Research (AAR) , 2018, DOI: 10.4236/aar.2018.75008
Abstract: Telomere, the nucleoprotein structure at the end of eukaryotic linear chromosomes is indispensable for maintaining the genome stability. Telomeric DNA loss is apparent with each cell division, which marks an endpoint to the indefinite replication of the cell by causing replicative senescence that may lead to the programmed cell death. The loss of telomere is normal in cell division and as such after 20 - 40 divisions, telomere becomes too short to facilitate the capping function. Telomere uncapping or chromosomal free end causes a potential threat to the genomic stability and thus leads to the accumulation of chromosomal abnormalities that have been known to play a role in aging and cancer. Telomerase, the ribonucleoprotein complex, and its accessory proteins are required to maintain the telomere sequence. Telomerase plays a key role in maintaining the length of telomere by adding G-rich repeat sequences. Its activity has been found to be quite high in the gametes, stem cells and most importantly tumor cells. Almost 85% of tumor cells compensate for telomere loss aided by telomerase-associated protein complex and shelter in complex or telosome. However, 5% - 10% of the cells undergo telomerase-independent mechanism. This review presents the molecular view of the telomere and telomerase along with its associated complex structures. It also discusses its contrasting role in causing cellular senescence and promoting tumorigenesis.
CDK5RAP3 Is a Novel Repressor of p14ARF in Hepatocellular Carcinoma Cells
Grace Wing-Yan Mak, Wai-Lung Lai, Yuan Zhou, Mingtao Li, Irene Oi-Lin Ng, Yick-Pang Ching
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0042210
Abstract: CDK5 regulatory subunit associated protein 3 (CDK5RAP3) is a novel activator of PAK4 and processes important pro-metastatic function in hepatocarcinogenesis. However, it remains unclear if there are other mechanisms by which CDK5RAP3 promotes HCC metastasis. Here, we showed that in CDK5RAP3 stable knockdown SMMC-7721 HCC cells, p14ARF tumor suppressor was upregulated at protein and mRNA levels, and ectopic expression of CDK5RAP3 was found to repress the transcription of p14ARF. Using chromatin immunoprecipitation assay, we demonstrated that CDK5RAP3 bound to p14ARF promoter in vivo. Furthermore, knockdown of p14ARF in CDK5RAP3 stable knockdown HCC cells reversed the suppression of HCC cell invasiveness mediated by knockdown of CDK5RAP3. Taken together, our findings provide the new evidence that overexpression of CDK5RAP3 promotes HCC metastasis via downregulation of p14ARF.
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort
Dalton C Wamalwa, Elizabeth M Obimbo, Carey Farquhar, Barbra A Richardson, Dorothy A Mbori-Ngacha, Irene Inwani, Sara Benki-Nugent, Grace John-Stewart
BMC Pediatrics , 2010, DOI: 10.1186/1471-2431-10-33
Abstract: HIV-1-infected children aged 18 months-12 years were followed up at Kenyatta National Hospital, Nairobi after initiating NNRTI-based HAART. Cofactors for mortality were determined using multivariate Cox regression models.Between August 2004 and November 2008, 149 children were initiated on HAART of whom 135 were followed for a total of 238 child-years (median 21 months) after HAART initiation. Baseline median CD4% was 6.8% and median HIV-1-RNA was 5.98-log10 copies/ml. Twenty children (13.4%) died at a median of 35 days post-HAART initiation. Mortality during the entire follow-up period was 8.4 deaths per 100 child-years (46 deaths/100 child-years in first 4 months and 1.0 deaths/100 child-years after 4 months post-HAART initiation). On univariate Cox regression, baseline hemoglobin (Hb) <9 g/dl, weight-for-height z-score (WHZ) < -2, and WHO clinical stage 4 were associated with increased risk of death (Hb <9 g/dl HR 3.00 [95% C.I. 1.21-7.39], p = 0.02, WHZ < -2 HR 3.41 [95% C.I. 1.28-9.08], p = 0.01, and WHO clinical stage 4, HR 3.08 [1.17-8.12], p = 0.02). On multivariate analysis Hb < 9 g/dl remained predictive of mortality after controlling for age, baseline CD4%, WHO clinical stage and weight-for-height z-score (HR 2.95 (95% C.I. 1.04-8.35) p = 0.04).High early mortality was observed in this cohort of Kenyan children receiving HAART, and low baseline hemoglobin was an independent risk factor for death.Sub-Saharan Africa carries the highest burden of paediatric HIV-1 with an estimated 1.8 million children < 15 years infected which represents 90% of all children living with HIV worldwide [1]. In Kenya there are approximately 150,000 HIV-1 infected children, out of whom nearly 60,000 are in need of antiretroviral therapy and about 25,000 are currently accessing treatment [2]. There is a concerted effort to raise the number of children on antiretroviral therapy through increased availability of early infant diagnosis and strengthening provider-initiated counseling
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