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Search Results: 1 - 10 of 4647 matches for " Gopal Patel "
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Use of Antimuscarinics in the Elderly
Bhavin Patel,Tamara Bavendam,Gopal Badlani
The Scientific World Journal , 2009, DOI: 10.1100/tsw.2009.55
Intramuscular lipoma of the pectoralis major muscle.
Gopal U,Patel M,Wadhwa M
Journal of Postgraduate Medicine , 2002,
Contamination of Lead and Mercury in Coal Basin of India  [PDF]
Reetu Sharma, Shobhana Ramteke, Khageshwar Singh Patel, Sudhanshu Kumar, Bighnaraj Sarangi, Shankar Gopal Agrawal, Lesia Lata, Huber Milosh
Journal of Environmental Protection (JEP) , 2015, DOI: 10.4236/jep.2015.612124
Abstract: The coal is contaminated with toxic metals at the trace levels. They are released into the environment during mining, handling and burning of coal. The Korba basin has one of the largest coal exploitation areas in the country. In this work, contamination and sources of toxic metals i.e. Hg and Pb in the air, soil and sediment of the Korba basin, India are described. The concentration of Hg and Pb in the ambient air was ranged from 7.4 - 29 and 7.0 - 585 ng/m3 with mean value of 18 ± 4 and 129 ± 104 ng/m3 in the winter season. The mean concentration of Hg in the soil and sediment was 0.22 ± 0.03 and 0.44 ± 0.08 mg/kg, respectively. The higher concentration of Pb in the environmental samples was observed.
Some Nonunique Common Fixed Point Theorems in Symmetric Spaces through Property
E. Karap?nar,D. K. Patel,M. Imdad,D. Gopal
International Journal of Mathematics and Mathematical Sciences , 2013, DOI: 10.1155/2013/753965
Some Nonunique Common Fixed Point Theorems in Symmetric Spaces through Property
E. Karap?nar,D. K. Patel,M. Imdad,D. Gopal
International Journal of Mathematics and Mathematical Sciences , 2013, DOI: 10.1155/2013/753965
Abstract: We introduce a new class of mappings satisfying the “common limit range property” in symmetric spaces and utilize the same to establish common fixed point theorems for such mappings in symmetric spaces. Our results generalize and improve some recent results contained in the literature of metric fixed point theory. Some illustrative examples to highlight the realized improvements are also furnished. 1. Introduction In 1986, Jungck [1] generalized the idea of weakly commuting pair of mappings due to Sessa [2] by introducing the notion of compatible pair of mappings and also showed that compatible pair of mappings commute on the set of coincidence points of the involved mappings. Recall that a point is called a coincidence point of the pair of self-mappings defined on if while the point is then called a point of coincidence for the pair . In the recent past and even now, the concept of compatible mappings is frequently used to prove results on the existence of common fixed points. The study of common fixed points of noncompatible pairs is also equally natural and fascinating. Pant [3] initiated the study of noncompatible pairs employing the idea of pointwise -weakly commuting pairs. Pant [4] proved an interesting fixed point theorem for maps satisfying Lipschitz type conditions. In recent years, the result of Pant [4] was generalized and improved by Sastry and Murthy [5] (see also [6]) by introducing the idea of tangential maps (or the property (E.A)) and -continuity. In continuation of this, Imdad and Soliman [7] and Soliman et al. [8] extended the results of Sastry and Murthy [5] as well as Pant [4] to symmetric space utilizing the idea of weakly compatible pair together with common property (E.A) (a notion due to Liu et al. [9]). For more references on the recent development of common fixed point theory in symmetric spaces, we refer readers to [10–14]. Most recently, Gopal et al. [15] improved these results by utilizing the idea of absorbing pair which is essentially due to Gopal et al. [16]. In this paper, we introduce a new notion called the common limit range property and show that this new notion buys a typically required condition up to a pair of mappings along with the notion of absorbing property in proving common fixed point theorems for Lipschitz type mappings in symmetric spaces. Consequently, the relevant recent fixed point theorems due to Soliman et al. [8] and Gopal et al. [15] are generalized and improved. 2. Preliminaries A symmetric on a nonempty set is a function which satisfies and (for all ). If is a symmetric on a set , then for and
Translational Regulation of Utrophin by miRNAs
Utpal Basu, Olga Lozynska, Catherine Moorwood, Gopal Patel, Steve D. Wilton, Tejvir S. Khurana
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0029376
Abstract: Background Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne Muscular Dystrophy (DMD) locus. Its regulation is of therapeutic interest as its overexpression can compensate for dystrophin's absence in animal models of DMD. The tissue distribution and transcriptional regulation of utrophin have been characterized extensively, and more recently translational control mechanisms that may underlie its complex expression patterns have begun to be identified. Methodology/Principal Findings Using a variety of bioinformatic, molecular and cell biology techniques, we show that the muscle isoform utrophin-A is predominantly suppressed at the translational level in C2C12 myoblasts. The extent of translational inhibition is estimated to be ~99% in C2C12 cells and is mediated by both the 5′- and 3′-UTRs of the utrophin-A mRNA. In this study we identify five miRNAs (let-7c, miR-150, miR-196b, miR-296-5p, miR-133b) that mediate the repression, and confirm repression by the previously identified miR-206. We demonstrate that this translational repression can be overcome by blocking the actions of miRNAs, resulting in an increased level of utrophin protein in C2C12 cells. Conclusions/Significance The present study has identified key inhibitory mechanisms featuring miRNAs that regulate utrophin expression, and demonstrated that these mechanisms can be targeted to increase endogenous utrophin expression in cultured muscle cells. We suggest that miRNA-mediated inhibitory mechanisms could be targeted by methods similar to those described here as a novel strategy to increase utrophin expression as a therapy for DMD.
Spatial analysis of malaria incidence at the village level in areas with unstable transmission in Ethiopia
Asnakew K Yeshiwondim, Sucharita Gopal, Afework T Hailemariam, Dereje O Dengela, Hrishikesh P Patel
International Journal of Health Geographics , 2009, DOI: 10.1186/1476-072x-8-5
Abstract: In this study, we examine the global and local patterns of malaria distribution in 543 villages in East Shoa, central Ethiopia using individual-level morbidity data collected from six laboratory and treatment centers between September 2002 and August 2006.Statistical analysis of malaria incidence by sex, age, and village through time reveal the presence of significant spatio-temporal variations. Poisson regression analysis shows a decrease in malaria incidence with increasing age. A significant difference in the malaria incidence density ratio (IDRs) is detected in males but not in females. A significant decrease in the malaria IDRs with increasing age is captured by a quadratic model. Local spatial statistics reveals clustering or hot spots within a 5 and 10 km distance of most villages in the study area. In addition, there are temporal variations in malaria incidence.Malaria incidence varies according to gender and age, with males age 5 and above showing a statistically higher incidence. Significant local clustering of malaria incidence occurs between pairs of villages within 1–10 km distance lags. Malaria incidence was higher in 2002–2003 than in other periods of observation. Malaria hot spots are displayed as risk maps that are useful for monitoring and spatial targeting of prevention and control measures against the disease.Malaria is a major public health problem in Africa with over 200 million clinical episodes and nearly one million deaths occurring annually [1,2]. However, the risks of morbidity and mortality associated with malaria, particularly in semi-arid and highland regions, vary spatially and temporally [3-5]. In semi-arid and highland regions of Africa, malaria is unstable and epidemic malaria is a common problem, causing an estimated 12.74 million clinical episodes and 155,000–330,000 deaths annually [4-6]. In Ethiopia, malaria is the leading cause of morbidity and mortality. About 70% of the population (Approximately 52 million people) is estimate
Post Keratoplasty Keratitis with Pandrug Resistant Pseudomonas spp. Showing False Susceptibility to Carbapenems
Munesh K Gupta, Tuhina Banerjee, Saurabh K Patel, Gopal Nath, Abhisekh Chandra, Ragini Tilak
Asian Journal of Medical Sciences , 2014, DOI: 10.3126/ajms.v5i1.8366
Abstract: Pandrug resistant Pseudomonas keratitis is an emerging cause of bacterial keratitis challenging clinicians for prompt and prudent treatment to avoid disaster of loss of eye. We report two cases of pandrug resistant keratitis following penetrating keratitis caused by Pseudomonas spp. It was only after a detailed laboratory characterization of the isolates that revealed their pandrug resistant character and helped in successful management of the condition. DOI: http://dx.doi.org/10.3126/ajms.v5i1.8366 Asian Journal of Medical Science Vol.5(1) 2014 pp.70-72
A Quantitative Analysis of Collision Resolution Protocol for Wireless Sensor Network  [PDF]
Reema Patel, Dhiren Patel
Journal of Software Engineering and Applications (JSEA) , 2015, DOI: 10.4236/jsea.2015.88036
Abstract: In this paper, we present formal analysis of 2CS-WSN collision resolution protocol for wireless sensor networks using probabilistic model checking. The 2CS-WSN protocol is designed to be used during the contention phase of IEEE 802.15.4. In previous work on 2CS-WSN analysis, authors formalized protocol description at abstract level by defining counters to represent number of nodes in specific local state. On abstract model, the properties specifying individual node behavior cannot be analyzed. We formalize collision resolution protocol as a Markov Decision Process to express each node behavior and perform quantitative analysis using probabilistic model checker PRISM. The identical nodes induce symmetry in the reachable state space which leads to redundant search over equivalent areas of the state space during model checking. We use “ExplicitPRISMSymm” on-the-fly symmetry reduction approach to prevent the state space explosion and thus accommodate large number of nodes for analysis.
Gastrointestinal stromal tumour in Meckel's diverticulum
K Chandramohan, Mudit Agarwal, Gopal Gurjar, Rohan C Gatti, Mahesh H Patel, Preeti Trivedi, Kiran C Kothari
World Journal of Surgical Oncology , 2007, DOI: 10.1186/1477-7819-5-50
Abstract: A 65 year old gentleman, presented with a pelvic mass. On exploratory laparotomy, it turned out to be gastrointestinal stromal tumour (GIST) arising from Meckel's diverticulum. Short history and review of literature are discussed.Neoplasms occurring from Meckel's diverticulum, even though rare, should be considered as differential diagnosis of pelvic masses arising from bowel, wherever imaging modalities fail to give a definitive diagnosis.Meckel's diverticulum, the most commonly encountered congenital anomaly of the small intestine, affects 2% of the population [1,2]. The vast majority of Meckel's diverticulae are incidentally discovered during autopsy, laparotomy, or barium studies [3]. Meckel's diverticulum is surgically removed only when a complication arises or a neoplasia develops. The tumors are infrequent and observed only in 0.5–3.2% of the Meckel's diverticula. Of these, 12% tumors are GIST. We are reporting one such incidence, where we came across a Meckel's diverticulum harboring GIST.Sixty-five year old gentle man presented with constipation for 4 months and bleeding per rectum for one month. Physical examination was unremarkable. Ultrasonography of the abdomen revealed 6 × 9 cms exophytic hypoechoic lesion in pelvis near sigmoid colon. Barium enema study was normal. Colonoscopy showed colitis from anal canal up to 20 cms. Rest of Colon was normal up to Caecum. Contrast enhanced computerized tomography (CT) scan showed lobulated mass lesion in pelvis posteriosuperior to the urinary bladder compressing anterior wall of sigmoid colon. CT scan picture was suggestive of soft tissue tumour in close relation to sigmoid colon or sigmoid mesentery (figure 1), a diagnosis of small bowel tumor compressing sigmoid colon was made. An exploratory laparotomy was done. On laparotomy, the lobulated tumour seems to be arising from an ileal diverticulum, which was very short in length and situated 50 cms from ileocaecal valve. So diagnosis was soft tissue tumour arising
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