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Search Results: 1 - 10 of 302 matches for " Germain Houngbedji "
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Morpho-Physical and Psycho-Social Determinants of Low Back Pain in Midwives Population in Benin  [PDF]
H. Etienne Alagnidé, Natta D. Didier Niama, Herman Azanmasso, M. Germain Houngbedji, E. Eric Dossa, G. Toussaint Kpadonou
Open Journal of Therapy and Rehabilitation (OJTR) , 2017, DOI: 10.4236/ojtr.2017.54010
Abstract: Background: Low back pain is a real public health problem. Lots of studies have been done about it, but not in midwives group. The latter seem to be exposed to low back pain due to morphological, physical and psycho-social factors. We therefore study the place of these factors in the occurrence of low back pain in midwives. Method: Prospective, cross-sectional and analytical study, it is done with 102 midwives of university hospitals in Benin. They were interviewed and examined. An eventual link with their history of low back pain, for at least 3 months during the last 12 months before the study, was checked to their morphological aspects (spinal curvatures, BMI), physical examinations data (strength and muscular flexibility) and psycho-social factors (relationship with colleagues and either, stress, ...). The effect of these factors was assessed using relative risk (RR) with a 95% confidence interval. Results: Different morpho-physical and psychosocial disturbances were observed in midwives. 81% had a history of low back pain. The latter have a statistically significant relationship with the different factors studied. These were mostly exposure factors, but poor midwife relationship with their hierarchical superiors was a protective factor (RR = 0.69 and p = 0.0106). Discussion-Conclusion: In Benin, health workers and especially midwives are very exposed to low back pain. The latter are often associated with different morphological, physical and psycho-social disturbances. The knowledge of those parameters is interesting to reduce this high prevalence of low back pain in midwives.
Satisfaction of Patients Treated in Physical Medicine and Rehabilitation Department in CNHU-HKM of Cotonou  [PDF]
Hountondji Etienne Alagnide, Didier Niama Natta, Germain Houngbedji, Mireille Adido, Jean Olouka, Eric Havyarimana, Godonou Toussaint Kpadonou
Open Journal of Therapy and Rehabilitation (OJTR) , 2018, DOI: 10.4236/ojtr.2018.61002
Abstract: Satisfaction of patients is an important dimension of the hospital management and the evaluation of the quality of care and services offered to patients. Objective: To estimate the degree of satisfaction of patients admitted in Physical Medicine and Rehabilitation Department in the National Hospital and University Center (CNHU-HKM) in Cotonou. Method: Cross-sectional study with descriptive and analytical aim. It was led from June 15th to October 15th 2013, on 158 patients or guides of children or not communicating patients having ambulatory care in the Department of Physical Medicine and Rehabilitation and who agree to participate to the study. The level of global satisfaction of the subjects was estimated with a digital scale from 0 to 10. It was secondarily transformed into a discreet qualitative variable. Result: Rate of participation was 63.2%. Patients had deficiencies of rheumatilogical origine (41.1%), neurological (27.2%), traumatological (24.1%). Their pathologies were evolving since 1 month to 10 years. It was about their first attendance of the Rehabilitation Department of CNHU-HKM in 72.2%. Patients’ degree of satisfaction was good for the deadliness of expectation, reception (80%), cleanliness of the building, respect of patients’ intimacy. Global satisfaction of patients was good in 72%. It was influenced by the deadline of evolution of the pathologies. Discussion-Conclusion: The level of satisfaction of patients admitted in the Rehabilitation Department in CNHU-HKM was acceptable. However, they are parameters that remain to be improved.
Skp2 and Skp2B team up against Rb and p53
Doris Germain
Cell Division , 2011, DOI: 10.1186/1747-1028-6-1
Abstract: The retinoblastoma (Rb) and the p53 pathways are two major mechanisms of tumor suppression. Disruption of these pathways is observed in most cancers. This review focuses on the description of two mechanisms by which both Rb and p53 pathways are disrupted simultaneously. First, the loss of the well known p16INK4a/p19ARF locus and second, the less well known amplification of the Skp2/Skp2B locus.The remarkable genetic organization of some loci suggests that evolution has selected mechanisms to maximize their biological impact. One example of such clever organization is the p16Ink4a/p19Arf locus. By using two distinct promoters, this locus allows the expression of two different proteins using overlapping genetic material (reviewed in [1]; the p16 protein, a cyclin-dependent kinase (cdk) inhibitor and ARF, an indirect regulator of the tumor suppressor gene p53.The cyclin dependent kinases (cdk) are a family of protein serine/threonine kinases, which control cell cycle progression through association with their regulatory subunits, known as cyclins. Cyclins are classified into a large number of subtypes including the D, E, A and B-type cyclins. Humans encode three D-type cyclins, cyclin D1, cyclin D2 and cyclin D3. D-type cyclins associate with cdk4 and 6 to promote the phosphorylation of the Retinoblastoma (Rb) protein (for review, [2]). Rb forms a complex with the E2F family of transcription factors and this represses their activity. Hyperphosphorylation of Rb results in the release of E2F, which then activates transcription of genes required for DNA replication and entry into S phase [3]. One of the early targets of E2F mediated transcription is cyclin E that, together with cdk2, acts to maintain Rb phosphorylation.Cyclin-cdk complexes are themselves regulated by two families of cdk inhibitors including p27 of the p21 family, which inhibits cyclin E-cdk2 complexes [4], and p16 of the INK4 family, which inhibits cyclin D-cdk4/6 complexes [5]. Functional disruption of t
The Challenges of the Local Management of Ethnic-Religious Diversity in Montreal: The Case of the Fitting Out of Places of Worship
Annick Germain
Revista CIDOB d'Afers Internacionals , 2007,
Abstract: Based on the case of Montreal, the author reviews the set of experiences of public intervention in the area of management of ethnic-religious diversity, which has led to the formulation of new debates with regard to the fit of this plurality in the urban space. The challenges posed by the incorporation of these new religious references in the configuring of the urban fabric also opens up questions on the meaning of cohabitation in increasingly plural neighbourhoods.
The Graz Declaration on Disability and Ageing 2006
Germain Weber
International Journal of Integrated Care , 2009,
Abstract:
La globalización de la cultura y la cuestión de la diversidad cultural: estudio de los flujos mundiales de traducciones entre 1979 y 2002.
Barré, Germain
REDES : Revista Hispana para el Análisis de Redes Sociales , 2010,
Abstract: The article presents a challenge to cultural diversity through the study of translation flows between 1979 and 2002. With the help of network analysis or method "structural" indicators are used to measure cultural diversity and assess the recognition of different languages. For example, there is a clear decline in the diversity of exchange translation from 1989.Using this method, we also understand the changing structure translation flows and, consequently, the dynamics of these flows. Thus, it is possible when the structure flows translations are stable in the 80's: around opposing English and Russian languages, two major groups. After the fall of the Berlin Wall preferential translation relations between the official languages of the former communist countries disappear, while the centrality of English becomes more important. In general, the choice of language works to be translated is based, above all, on geographical and political considerations.In summary, network analysis provides a different vision of globalization. Thus, it seems important that tools like this to be integrated in future studies related to this issue.
La mondialisation de la culture et la question de la diversité culturelle: étude des flux mondiaux de traductions entre 1979 et 2002.
Barré, Germain
REDES : Revista Hispana para el Análisis de Redes Sociales , 2010,
Abstract: The article presents a challenge to cultural diversity through the study of translation flows between 1979 and 2002. With the help of network analysis or method "structural" indicators are used to measure cultural diversity and assess the recognition of different languages. For example, there is a clear decline in the diversity of exchange translation from 1989.Using this method, we also understand the changing structure translation flows and, consequently, the dynamics of these flows. Thus, it is possible when the structure flows translations are stable in the 80's: around opposing English and Russian languages, two major groups. After the fall of the Berlin Wall preferential translation relations between the official languages of the former communist countries disappear, while the centrality of English becomes more important. In general, the choice of language works to be translated is based, above all, on geographical and political considerations.In summary, network analysis provides a different vision of globalization. Thus, it seems important that tools like this to be integrated in future studies related to this issue.
Télémonitorage des grandes fonctions physiologiques chez les primates vigiles Remote monitoring of physiologic functions in monkeys
Guy?Germain
Revue de Primatologie , 2011, DOI: 10.4000/primatologie.533
Abstract: Les caractéristiques communes à l'étude des primates non-humains sont proches des contraintes que l'on rencontre dans l'application des principes de la télémédecine humaine. Elles découlent de l’éloignement des animaux et de leur dispersion géographique pour les études en milieu naturel, elles découlent aussi du besoin de contr ler au laboratoire les traitements expérimentaux en perturbant le moins possible le comportement social des animaux. Les ondes radio sont un excellent signal de transmission pour le suivi des animaux parce qu'elles peuvent propager des informations rapidement et sur de longues distances dans l'air. Tous les dispositifs télémétriques consistent en un ou plusieurs capteurs couplés à un émetteur encodeur radio et d'un système d'antenne couplé à un récepteur décodeur, analogique ou numérique. Le progrès des télétransmissions résulte par ailleurs de la miniaturisation des dispositifs électroniques d'acquisition et d'émission qui sont de moins en moins gourmands en énergie et acquièrent des durées d'autonomie beaucoup plus grande. De nombreux dispositifs télémétriques très souvent totalement implantables dans le corps de l'animal sont aujourd'hui commercialement disponibles. Ils permettent une surveillance détaillée des paramètres physiologiques des systèmes cardiovasculaire, nerveux, locomoteur, métabolique, respiratoire et reproducteur chez les primates non-humains entièrement libres de leurs mouvements. Ils sont très largement exploités dans les études pharmacologiques et toxicologiques. D'autres dispositifs encore au stade expérimental intègrent également la combinaison de l'enregistrement télémétrique des pressions, biopotentiels musculaires ou nerveux, température, avec des enregistrements audio et vidéo pouvant être eux-mêmes acquis et transmis, partiellement ou en totalité, par télémétrie. Le développement des systèmes futurs sera probablement axé sur les besoins accrus de caractériser des individus très mobiles ou des groupes d’animaux dans des environnements complexes, toujours en utilisant des systèmes portables et les moins invasifs possible. Ces systèmes devraient permettre de caractériser les tendances évolutives de certains états physiologiques (études éthophysiologiques, études de terrain) ou expérimentaux (physiologie, pharmacologie) et d'alerter suffisamment rapidement les observateurs pour qu'ils puissent appliquer en retour des actions correctives si nécessaire. Des pans entiers des grandes fonctions physiologiques, régulations métaboliques et régulations hormonales, pour ne citer que celles-là, ne peuvent pas encore
De l’usure au pouvoir de l’argent : les métamorphoses d’un mythe antijuif à travers la caricature en Angleterre From Usury to High Finance: The Metamorphosis of an AntiJewish Myth viewed through English Caricatures
Lucienne Germain
Revue LISA / LISA e-journal , 2009, DOI: 10.4000/lisa.3120
Abstract: “Jewish Money Power”, the “Wandering Jew” and the “Blood Libel” (ritual murder) myths are the three pillars of the anti-Semitic iconography which developed during the Middle Ages. Throughout the centuries, their evolution has continuously reflected the beliefs and tastes of the various societies which have used them to stereotype Jewish otherness. Far from being exhaustive, the intent of this article, based on a limited number of caricatures, is to stress the changes which took place over the centuries in numerous and varied portrayals of the “Jewish Money Power”: from the Jew in his capacity as money lender to the Jew as stockbroker, to more contemporary images of the Jewish banker and international financier, monopolising high finance, insinuating himself in all fields and plotting to dominate and destroy the Christian world. Having explained the various transformations in context, this analysis of selected Jewish graphic portrayals will also highlight the constant use of physical features and characteristics that have contributed to creating a misleading image of the Jews and encouraged anti-Semitism.
mRNA export: threading the needle
Hugo Germain
Frontiers in Plant Science , 2013, DOI: 10.3389/fpls.2013.00059
Abstract: After mRNA biogenesis, several proteins interact with the messenger to ensure its proper export to the cytoplasm. Some of these proteins will bind RNA early on, at the onset of transcription by RNA polymerase II holoenzyme, while others will join later for downstream processing steps, such as poly-adenylation or splicing, or may direct mRNA ribonucleoprotein particle migration to the nucleopore. We recently discovered that Arabidopsis plant knockout for the protein MOS11 (MODIFIER OF SNC1, 11) partially suppresses autoimmune responses observed in the TNL-type [TIR/NBS/LRR (Toll-interleukin-like receptor/nucleotide-binding site/C-terminal leucine-rich repeat)] R gene gain-of-function variant snc1 (suppressor of npr1-1, constitutive 1). This suppression of resistance to pathogens appears to be caused by a decrease in nuclear mRNA export in mos11-1 snc1 plants. In humans, the putative ortholog of MOS11, CIP29 (29-kDa cytokine-induced protein), interacts with three proteins that are also involved in mRNA export: DDX39 (DEAD-box RNA helicase), TAF15 of the FUS family (FUSED IN SARCOMA), and ALY (ALWAYS EARLY), a protein implicated in mRNA export in mammalian systems. These proteins have received very little attention in plants. Here, we will discuss their particularities and role in mRNA export and biotic stress.
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