Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Search Results: 1 - 10 of 2026 matches for " Geoffrey Omuse "
All listed articles are free for downloading (OA Articles)
Page 1 /2026
Display every page Item
Prevalence of Panton Valentine Leukocidin in Carriage and Infective Strains of Staphylococcus aureus at a Referral Hospital in Kenya  [PDF]
Geoffrey Omuse, Patricia Shivachi, Samuel Kariuki, Gunturu Revathi
Open Journal of Medical Microbiology (OJMM) , 2013, DOI: 10.4236/ojmm.2013.31002
Abstract: Panton valentine leukocidin (PVL) is a pore forming exotoxin that is expressed by some Staphylococcus aureus (S. aureus) strains and is thought to add to its virulence. The prevalence of PVL in carriage and disease causing strains varies considerably from region to region. This study compared the prevalence of the PVL gene in S. aureus isolates obtained from healthcare workers and from patients seen at the Aga Khan University Hospital Nairobi (AKUHN). S. aureus isolates obtained from healthcare workers and patients attended to at AKUHN between July 2010 and March 2011 were used for this study. Forty five S. aureus isolates from healthcare workers and 63 from clinical specimens obtained from 59 patients were analysed for the PVL gene. The prevalence of PVL in isolates from healthcare workers was 24.4% compared to 39.7% in the isolates causing infection (P = 0.098). PVL prevalence was 58.8% in S. aureus isolates obtained from skin and soft tissue infections (SSIs) compared to 25.0% in carriage isolates (P = 0.002, OR 4.29). Prevalence in isolates from invasive infections was 11.1%. Patients with PVL positive S. aureus were younger than those with PVL negative isolates (P
Characteristics of Archived Coagulase Negative Staphylococci Isolates at a University Hospital, Nairobi, Kenya  [PDF]
Shivachi Patricia Ingato, Andrew Nyerere Kimang’a, Geoffrey Omuse, Samuel Kariuki, Revathi Gunturu, Victor Dinda
Open Journal of Medical Microbiology (OJMM) , 2014, DOI: 10.4236/ojmm.2014.44026
Abstract: Background: Coagulase negative Staphylococci (CoNS) are normal inhabitants of the skin and mucous membranes and thus have been dismissed for a long time as culture contaminants even if they have been isolated from sterile specimens. The risk factors for CoNS infections include patients who are immunocompromised, implanted with foreign bodies or with indwelling devices. The aim of this study was to determine the antimicrobial susceptibility patterns and presence of mecA gene in methicillin resistant CoNS isolated in a teaching and referral hospital in Kenya. Methodology: This was a cross sectional retrospective study. Archived isolates were sub-cultured on 5% sheep blood agar. Speciation and antimicrobial susceptibility patterns were performed by Vitek2 technique. The presence of mecA gene was determined by (PCR). Results: A total of seven species were identified with Staphylococcus epidermidis having the highest percentage at 45.4% and Staphylococcus warneri with the lowest at 2.6%. High resistance to antibiotics that were tested was observed regardless of the source of the isolate. MecA gene was found in 90% of the isolates. Conclusion: Coagulase negative Staphylococci exhibited high levels of resistance generally. Most of the isolates carried the mecA gene. Despite some of the isolates being resistant to Cefoxitin, the mecA gene was not found. There is a possibility that methicillin resistance in these isolates is mediated using a different mechanism.
Matrices That Commute with Their Conjugate and Transpose  [PDF]
Geoffrey Goodson
Advances in Linear Algebra & Matrix Theory (ALAMT) , 2013, DOI: 10.4236/alamt.2013.33005

It is known that if A∈Mn is normal (AA*=A*A) , then AA ̄=A ̄A if and only if AAT=ATA. This leads to the question: do both AA ̄=A ̄A and AAT=ATA imply that A is normal? We give an example to show that this is false when n=4, but we show that it is true when n=2 and n=3.

Groups Having Elements Conjugate to Their Squares and Connections with Dynamical Systems  [PDF]
Geoffrey R. Goodson
Applied Mathematics (AM) , 2010, DOI: 10.4236/am.2010.15055
Abstract: In recent years, dynamical systems which are conjugate to their squares have been studied in ergodic theory. In this paper we study the consequences of groups having elements which are conjugate to their squares and consider examples arising from topological dynamics and more general dynamical systems
Pharmacological Adjuvants to Limit Erythropoietin Stimulating Agents Exposure  [PDF]
Iqbal Masood, Geoffrey Teehan
Open Journal of Nephrology (OJNeph) , 2012, DOI: 10.4236/ojneph.2012.24015
Abstract: Anemia in chronic kidney disease (CKD) is common, causing morbidity and mortality, and is primarily due to reduced erythropoietin (EPO) release and, to a lesser degree, shortened red cell survival. Erythropoietin Stimulating Agents like epoetin Alfa and darbepoetin alpha are used commonly to treat this form of anemia. Recent evidence suggests increased morbidity and mortality associated with higher hemoglobin in the setting of these agents use. Whether these complications are due to higher dose of erythropoietin or its resistance (i.e. inflammation), or achieving a higher hemoglobin remains unclear. Tightening restrictions on these agents has led to increase interest in the use of non-ESA adjuvants to improve erythropoiesis. This review will highlight the most promising of these agents.
A Case of Type I Hepatorenal Syndrome Treated with Vasopressin  [PDF]
Laura Connor, Geoffrey Teehan
Open Journal of Nephrology (OJNeph) , 2013, DOI: 10.4236/ojneph.2013.33025

Hepatorenal syndrome (HRS) is a grave complication of end-stage liver disease and is associated with a very high mortality. This case report described a 42-year-old female with advanced alcohol-induced cirrhosis who developed HRS that was initially treated with Midodrine and Octreotide but renal function continued to deteriorate. Vasopressin therapy was added and HRS was successfully reversed. There are few data available on the use of vasopressin for HRS and this case supports its use in treatment of HRS, particularly in countries where the more widely studied Terlipressin is unavailable. This case also demonstrates that a patient failing one medical therapy for HRS may respond to an alternative or adjunctive therapy. Therefore, this should be attempted to increase the patient’s chance of survival.

Forensic odontostomatology  [PDF]
Geoffrey H. Sperber
Forensic Medicine and Anatomy Research (FMAR) , 2013, DOI: 10.4236/fmar.2013.14019
Abstract: Teeth are the most durable and enduring structures of human anatomy, surviving fragmentation, partial incineration and severe decomposition. The role of teeth in identification is manifested as significant specifiers of deceased or living individuals. The characteristics of dentalmorphology are genetically-inherited and ascribable to racial or familial ancestry. Dental age identification is attributable to young individuals. The chemical composition of teeth identifies diets during life, as attritional wear patterns do. Bite marks transiently relate to the perpetrator of attacks. Dental restorations and prostheses are evidence of economic, cultural and social status of deceased individuals. Palatal rugae patterns are unique to individuals. The DNA identification of postmortem dental pulp tissue relating to a deceased individual or a living relative is the ultimate criterion of positive association of forensic recognition, as other means of identification become less effective, forensic dental identification increases in importance.
Letter to the Editor  [PDF]
Geoffrey H. Sperber
Forensic Medicine and Anatomy Research (FMAR) , 2013, DOI: 10.4236/fmar.2013.14012
Abstract: Letter to the Editor; Forensic Medicine and Anatomy Research
Manufacture of a Low Oxalate Mitsumame-Type Dessert Using Rhubarb Juice and Calcium Salts  [PDF]
Sophie Faudon, Geoffrey Savage
Food and Nutrition Sciences (FNS) , 2014, DOI: 10.4236/fns.2014.517174
Abstract: Rhubarb (Rheum rhabarbarum) juice was used to make a Japanese soft mitsumame-type dessert sweet. The dessert was prepared from extracted rhubarb juice, which was cooked with sugar, agar and guar gum, then allowed to set in sweet moulds. The total, soluble and insoluble oxalates were determined in the ingredients and the final products using HPLC chromatography. To reduce the soluble oxalate content of the dessert while retaining the colour and taste of the final product, increments of CaCl2 and CaCO3 were added to the test dessert mixes. The addition of CaCl2 reduced the pH from 3.55 ± 0.03 to pH 3.09 ± 0.02 while addition of CaCO3 increased the pH from 3.55 ± 0.03 to 4.96 ± 0.01. In both cases, the incremental addition of calcium reduced the soluble oxalate content of the sweets by converting it to insoluble oxalate.
Calcium and Oxalate Contents of Curly Leaf ( Petroselinum crispum) and Flat Leaf ( P. crispum var. neapolitanum ) Parsley Cultivars  [PDF]
Geoffrey Savage, Leo Vanhanen
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.616161
Abstract: The total, soluble and insoluble oxalate contents of the leaves and stems of curly leaf (Petroselinum crispum) and flat leaf (P. crispum var. neapolitanum) parsley cultivars were extracted from fresh tissue and measured using HPLC chromatography. There were no significant differences between the total and insoluble oxalate contents of the leaves between the flat leaf and curly leaf cultivars. There was a small difference (P < 0.05) between the soluble oxalate contents of the leaves of the two cultivars. The mean total, soluble and insoluble oxalates of the leaves of the two cultivars were 1137.0, 177.9 and 959.3 mg/100 g dry matter (DM), respectively. The mean total, soluble and insoluble oxalate contents of the stems were 1680.7, 386.2 and 1294.5 mg/100 g DM, respectively, and these were significantly higher than the mean values for the leaves of the two cultivars. Insoluble oxalate made up a mean of 77.0% of the curly leaf stems and leaves compared to a mean of 84.4% found in the flat-leaved cultivar. Unavailable calcium, that is, calcium bound to oxalate as insoluble oxalate, made up a mean of 26.9% of the total calcium in the leaves of both cultivars while the unavailable calcium made up 45.0% of the total calcium in the stems of the two cultivars. Overall, the oxalate contents of both parsley cultivars are relatively high, on a dry matter basis, but their overall contribution to dietary intake is likely to be quite small as parsley is an herb that is only used in small amounts to garnish foods.
Page 1 /2026
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.