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Search Results: 1 - 10 of 144574 matches for " Gaia F Biggi "
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Analysis of wheat SAGE tags reveals evidence for widespread antisense transcription
Rebecca L Poole, Gary LA Barker, Kay Werner, Gaia F Biggi, Jane Coghill, J George Gibbings, Simon Berry, Jim M Dunwell, Keith J Edwards
BMC Genomics , 2008, DOI: 10.1186/1471-2164-9-475
Abstract: Examination of 71,930 Long SAGE tags generated from six libraries derived from two wheat genotypes grown under two different conditions suggested that SAGE is a reliable and reproducible technique for use in studying the hexaploid wheat transcriptome. However, our results also showed that in poorly annotated and/or poorly sequenced genomes, such as hexaploid wheat, considerably more information can be extracted from SAGE data by carrying out a systematic analysis of both perfect and "fuzzy" (partially matched) tags. This detailed analysis of the SAGE data shows first that while there is evidence of alternative polyadenylation this appears to occur exclusively within the 3' untranslated regions. Secondly, we found no strong evidence for widespread alternative splicing in the developing wheat grain transcriptome. However, analysis of our SAGE data shows that antisense transcripts are probably widespread within the transcriptome and appear to be derived from numerous locations within the genome. Examination of antisense transcripts showing sequence similarity to the Puroindoline a and Puroindoline b genes suggests that such antisense transcripts might have a role in the regulation of gene expression.Our results indicate that the detailed analysis of transcriptome data, such as SAGE tags, is essential to understand fully the factors that regulate gene expression and that such analysis of the wheat grain transcriptome reveals that antisense transcripts maybe widespread and hence probably play a significant role in the regulation of gene expression during grain development.With cereals constituting more than 60% of the world's dietary intake, the bread wheat Triticum aestivum is one of the most important crops in world agriculture [1,2]. Despite the high yields achieved in Europe there is still a real need to generate improved cultivars, as yield and flour quality can be dramatically affected by the environment. This need has become even greater in recent years with tight
Autologous chondrocyte implantation for focal cartilage defects in athletes: histology and second-look arthroscopy
A. Scorrano,F. Biggi,G. Turi
Journal of Orthopaedics and Traumatology , 2004, DOI: 10.1007/PL00021718
Abstract: Macroscopic and histologic evaluations showed repair tissue with the characteristics of normal cartilage.
DEXA evaluation of total hip arthroplasty with neck-preserving technique: 4-year follow-up
F. Biggi,F. Franchin,R. Lovato,F. Pipino
Journal of Orthopaedics and Traumatology , 2004, DOI: 10.1007/s10195-004-0063-4
Abstract: Periprosthetic bone remodeling, and its evaluation, are the keys of long-term survival of cementless total hip arthroplasty. Dual energy X-ray absorptiometry (DEXA) is the most accurate method to measure bone mineral density, evaluating the effects of bone-prosthesis interactions. We studied, 4 years after implantation, 10 patients who underwent total hip arthroplasty with the CFP prosthetic stem and TOP acetabular cup (Waldemar Link, Hamburg, Germany). Our results demonstrate minimal periprosthetic bone loss compared to that normally observed with conventional stems. A few cases exhibited an increase in BMD. We believe that primary stability, prosthetic design, preservation of natural neck anteversion and off-set, better function related to muscle lever arm, and physiological bone loading with natural stress distribution are the keys of this succesful mini-invasive total hip replacement system.
Biomaterials in Maxillofacial Surgery: Membranes and Grafts
Luigi F. Rodella,Gaia Favero,Mauro Labanca
International Journal of Biomedical Science , 2011,
Abstract: Today, significant differences in the use of biomaterials (membranes and grafts) of animal or synthetic origin have yet to be reported. Nevertheless, some evidences suggest that synthetic materials have a lower risk of disease transmission. This review aims to assess the available informations on regenerative bone technique using reasorbable membranes and bone grafts. In particular, biocompatibility, immunological response, tissue reaction, reabsorption time and histological features of materials daily use in dentistry and in maxillofacial surgery were emphasized
Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery
F. Randelli,F. Biggi,G. Della Rocca,P. Grossi,D. Imberti,R. Landolfi,G. Palareti,D. Prisco
Journal of Orthopaedics and Traumatology , 2011, DOI: 10.1007/s10195-010-0125-8
Abstract: Anticoagulant prophylaxis for preventing venous thromboembolism (VTE) is a worldwide established procedure in hip and knee replacement surgery, as well as in the treatment of femoral neck fractures (FNF). Different guidelines are available in the literature, with quite different recommendations. None of them is a multidisciplinary effort as the one presented. The Italian Society for Studies on Haemostasis and Thrombosis (SISET), the Italian Society of Orthopaedics and Traumatology (SIOT), the association of Orthopaedists and Traumatologists of Italian Hospitals (OTODI), together with the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI) have set down easy and quick suggestions for VTE prophylaxis in hip and knee surgery as well as in FNF treatment. This inter-society consensus statement aims at simplifying the grading system reported in the literature, and its goal is to benefit its clinical application. Special focus is given to fragile patients, those with high bleeding risk, and those receiving chronic antiplatelet (APT) and vitamin K antagonists treatment. A special chapter is dedicated to regional anaesthesia and VTE prophylaxis.
II Italian intersociety consensus statement on antithrombotic prophylaxis in orthopaedics and traumatology
F. Randelli,E. Romanini,F. Biggi,G. Danelli,G. Della Rocca,N. R. Laurora,D. Imberti,G. Palareti,D. Prisco
Journal of Orthopaedics and Traumatology , 2013, DOI: 10.1007/s10195-012-0214-y
Abstract: Pharmacological prophylaxis for preventing venous thromboembolism (VTE) is a worldwide established procedure in hip and knee replacement surgery, as well as in the treatment of femoral neck fractures, but few data exist in other fields of orthopaedics and traumatology. Thus, no guidelines or recommendations are available in the literature except for a limited number of weak statements about knee arthroscopy and lower limb fractures. In any case, none of them are a multidisciplinary effort as the one here presented. The Italian Society for Studies on Haemostasis and Thrombosis (SISET), the Italian Society of Orthopaedics and Traumatology (SIOT), the Association of Orthopaedic Traumatology of Italian Hospitals (OTODI), together with the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) and the Italian Society of General Medicine (SIMG) have set down easy and quick suggestions for VTE prophylaxis in a number of surgical conditions for which only scarce evidence is available. This inter-society consensus statement aims at simplifying the approach to VTE prophylaxis in the single patient with the goal to improve its clinical application.
Recovery of Hunger Sensations Associated with Low Preprandial Blood Glucose: An Easy Exit from Diabetes?  [PDF]
Mario Ciampolini, Gaia Cecchi
Open Journal of Preventive Medicine (OJPM) , 2016, DOI: 10.4236/ojpm.2016.65014
Abstract: Background: Obesity, diabetes, asthma, autism, birth defects, dyslexia, attention deficit-hyperactivity disorder and schizophrenia have increased in children in the last half century. These increases may depend on the widespread, well known error in energy balance: the unremitting addition of fat at any will (decision) to eat. In most (60%) but not all people, the decision arises as conditioned before energy exhaustion of the energy available from previous meals. After meal suspension for few hours (up to 48 hours), healthy subjects identified the arousal of sensations of hunger that we named Initial Hunger (IH). After this identification, subjects distinguished IH from conditioned sensations before subsequent meals by mental comparison of the current arousal with the remembered IH. BG decreased to 76.6 ± 3.7 mg/dL and hunger sensations (Initial hunger, IH) arose spontaneously and corresponded to the complete exhaustion of the previous meals. Objective: Not Insulin Dependent (NID) diabetic people differ from fattening people in this: after meal suspension, they do not develop any hunger sensation nor the associated low blood glucose (BG). Methods: Meal suspension lets IH arise and after no arousal, reduction of energy intake. The two subjects consumed meals that provided at least 20 grams of animal protein and up to one kg of not-starchy vegetable (NSV) for 6 to 12 months. At reappearance of IH, we implemented an Initial Hunger Meal Pattern (IHMP). Results: We tried to implement IHMP training in two obese (BMI of 39 and 33) adults out of two consecutive recruitments of subjects who showed high fasting BG. We found an absence of BG decline to 76.6 ± 3.7 mg/dL and an absence of any hunger sensation after eating suspension. Both subjects lost 13% - 20% of their body weight and recovered 76.6 ± 3.7 mg/dL of BG and hunger sensations, i.e., went off diabetes. IHMP maintained the decreased body weight in the subsequent months. Conclusion: Diabetes develops for inveterate conditioned intake (when previous energy intake has not been fully exhausted before meals), excessive fattening (with presumed excessive post-absorption emission of fatty acids from fatty tissues), permanent loss of BG decline to 76.6 ± 3.7 mg/dL and permanent loss of physiological signals of hunger. A healthy, non-diabetic life may be recovered by painless loss of weight up to 20%. The body weight remained stable by implementing IHMP at reappearance of hunger sensations. This costs accurate energy intake planning instead of hunger endurance.
Sulle tracce della Mamá Grande. La costruzione dell'immaginario femminile nell’opera di Gabriel García Márquez
Gaia Marzo
Altre Modernità , 2010,
Abstract: Sulle tracce della Mamá Grande. La costruzione dell'immaginario femminile nell’opera di Gabriel García Márquez Scheda tesi di Gaia Marzo RELATORE: Prof. Paolo Proietti CORSO DI LAUREA: Comunicazione e gestione nei mercati dell’arte e della cultura UNIVERSITA': Libera Università di Lingue e Comunicazione IULM di Milano ANNO ACCADEMICO: 2008/2009
Due sotto l'impero. India e Australia nel XIX secolo
Gaia Giuliani
Scienza & Politica : per una Storia delle Dottrine , 2009, DOI: 10.6092/issn.1825-9618/2742
Abstract: Due sotto l’impero. India e Australia nel XIX secolo
From Land art to the “global era”
Gaia Salvatori
JCOM : Journal of Science Communication , 2008,
Abstract: In the globalisation era, arts have provided food for thought on “how latitudes became forms”, to stress again that now, at global level, one should no longer define art as a contemplation “space”, but as an “environment”, a place for experience. On the other hand, already when Bern saw the inauguration of the historic exhibition “When Attitudes became Forms” in 1969, people realised that the problem was lying in the behaviour, in the attitude, of making arts towards the world. Basically, the formalistic concept of self-referentiality in a work of art was to be overcome, and attention was to be paid to procedures and contexts. In search of a new humanism in contact with the natural universe.
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