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Search Results: 1 - 10 of 471802 matches for " Gabriela Samaha Fran?a "
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Venous Catheterization Experimental Model in Rabbits: Histological Alterations in the Catheter Region  [PDF]
Bianca Ribeiro Rodrigues, Gabriela Samaha Frana, Maria Cecília Ferro, Canabarro Luciana, Willy Marcus Frana
Surgical Science (SS) , 2015, DOI: 10.4236/ss.2015.612076
Abstract: Central venous access is one of the most common surgery procedures worldwide, especially in pediatric surgery. Local and regional complications as the result of venous catheter permanence time are frequently described as: thrombosis, infection, edema and local cellulite, movement and loss of the catheter. Other severe complications such as endocardiac and hemorrhagic lesions are also described and considered the cause of catheter early removal. In the literature few studies have addressed vascular and perivascular lesions and complications as the result of central venous access to peripheral veins, given the difficulty of setting up venous catheterization experimental models to study blood vessels and perivascular tissue alterations after catheterization. In the present venous catheterization experimental model, rabbits were divided into two groups based on the time that the venous catheters were maintained in their veins. Group a composed of 7 New Zealand male rabbits was submitted to a 15-day treatment; and the 6 New Zealand male rabbits of group B were treated during 90 days. Both groups presented similar inflammatory conditions since there was no significant difference between groups. Therefore, the results may well suggest that the endothelial inflammatory reaction could have developed at an early initial short period and by maintaining the catheter, the inflammatory reactions would have decreased or disappeared. Aimed at studying these vascular and perivascular alterations in venous catheterization, the present study proposes an experimental rabbit model that allows the analysis of differences in local vascular and perivascular histological variations and compares histological differences between both venous catheterization groups each of them with different periods of treatment.
Histological and Morphological Study of the Intestines of Wistar Rat Fetuses in a Modified Gastroschisis Experimental Model  [PDF]
André Luis Hecht Sartori, Marina Ferreira Rosa de Vilhena, Gabriela Samaha Frana, Willy Marcus Frana
Surgical Science (SS) , 2016, DOI: 10.4236/ss.2016.72010
Abstract: In gastroschisis (G), the lesion degree of exposed intestinal segments is related to the time of its contact with the amniotic fluid (AF) and exposure to meconium which is the cause of intestinal morphological and histological alterations. The outcome of these alterations is intestinal hypoperistalsis and nutrient absorption deficiency, which contribute to increased morbidity and high medical-hospital costs. In this study, morphological and histological intestine alterations were identified at two different contact occasions with AF. Experimental gastroschisis (G) was performed on Wistar rat fetuses at a single gestational age on day 18.5th. The fetuses were removed on the 20.5th (G-1) and 21.5th days (G-2). Fetuses of both groups were divided in 3 sub-groups: control (C), gastroschisis (G) and sham (S). Measurements were taken of the Whole Set including fetus, placenta and membranes with AF (WS), fetus body weight (BW), intestinal weight (IW) and their diameters (DI). The objective of the present study is to test a new gastroschisis experimental model and identify differences in morphological and histological alterations in these two gestational periods that may be directly related to intestinal motility disorders in G. The WS and BW presented no significant statistical difference when compared G1 and G2. The results of the intestine average weight of G2 fetuses were significantly higher when compared to G1 fetuses in all subgroups (C: p = 0.02; G: p = 0.01; S: p = 0.02, Mann Whitney). The results of the intestinal average diameters (D/d) in G1 and G2 presented significant statistical difference only in G subgroup (p < 0.05, Kruskal Wallis). When compared intestinal average diameters, there was significant statistical difference of G fetuses in G1 and G2 (p < 0.05, Mann Whitney). In conclusion, the present experimental G model was adequate to reproduce G in rat fetuses. All G fetuses presented significant statistical difference when compared to other group in their subgroup and when compared G1 and G2 (p < 0.05). These alterations can explain the difficulties in accomplishing adequate peristalsis in G neonate bearers.
La Peur de Guy Maupassant sob o enfoque da tradu o
Gabriela de Frana Nanni
Tradu??o & Comunica??o : Revista Brasileira de Tradutores , 2006,
Abstract: O presente artigo consiste em apresentar os comentários decorrentes do processo tradutório para o português do conto La Peur, de Guy de Maupassant. Tais justificativas baseiam-se fundamentalmente nas reflex es passadas pelo crítico literário John Gledson, tradutor para o inglês de Machado de Assis, Roberto Schwartz e Milton Hatoun, ao longo de uma disciplina oferecida pela Pós-Gradua o em Estudos da Tradu o - UFSC, bem como nos pressupostos teóricos de Todorov acerca da literatura fantástica.
Mudan?as no ambito da testagem anti-HIV no Brasil entre 1998 e 2005
Frana Junior,Ivan; Calazans,Gabriela; Zucchi,Eliana Miura; ,;
Revista de Saúde Pública , 2008, DOI: 10.1590/S0034-89102008000800011
Abstract: objective: to analize changes in hiv testing, reasons reported by those who were tested or not and received counseling. methods: cross-sectional studies conducted in both men and women aged 16 to 65 years based on representative samples of urban brazil in 1998 (n=3,600) and 2005 (n=5,040). sociodemographic, sexual, reproductive characteristics, life experiences and health data were collected and analyzed. potential differences in the distribution of variables was analyzed using pearson's chi-square and design-based f test (±<5%). results: in 1998 and 2005, 20.2% and 33.6% of interviewees had been tested, respectively. a total of 60% women aged 25-34 years were tested, but those who reported sexual initiation before the age of 16 and four or more sexual partners in the fi ve years prior to the interview were less tested. there was no significant increase in testing among men, except among those aged 55-65 years, per capita income between 1-3 and 5-10 monthly minimum wages, retired, historical protestant and followers of african-brazilian religions, living in the north/northeast region and who reported homosexual/bisexual partners or no sexual relationship in the five years prior to the interview. testing rates did not increase in those who self-reported as high risk for hiv. among women, prenatal testing rate increased while work-related testing decreased among men. in 2005, half of those who were tested did not receive any advice before or after testing. conclusions: hiv testing scaling up was unequal and was mostly seen among women at childbearing age, adults and those better off. there seems to be an increase in testing rates in brazil but without regard for people's right to free choice and without offering more widely and better quality counseling.
Antibiotic Effect on Planktonic and Biofilm-Producing Staphylococci  [PDF]
Hassan A. M. Samaha, Mohamed H. Al-Agamy, Wafaa E. Soliman
Advances in Microbiology (AiM) , 2017, DOI: 10.4236/aim.2017.76039
Abstract: The pathogenic effect of Staphylococci is due to extra-cellular factors and properties such as adherence and biofilm production. The nature of the biofilm and the physiological properties of biofilm-producing bacteria result in an inherent antibiotic resistance and require further investigation. Two hundred and sixty Staphylococcal strains were cultured from 600 clinical specimens obtained from hospitalized patients. Among these, 155 were identified as coagulase-positive (CPS) and 105 as coagulase-negative (CNS) staphylococci. Staphylococcal strains were tested for biofilm production using the tissue culture plate (TCP) method. TCP detection showed that of the 155 CPS, 124 (80%) were biofilm producers, while 63 (60%) of the 105 CNS were biofilm producers. Biofilm-producing strains were scanned by scanning electron microscope (SEM) to confirm biofilm formation, study biofilm production, and examine antibiotic effects on biofilm formation. Disc diffusion method was used to study resistance of planktonic and biofilm-forming cells to antibiotics. Planktonic cells were less resistant to antibiotics than biofilm-forming cells. Microbroth dilution method and a new BioTimer assay were used to determine antibiotic MICs affecting planktonic and biofilm cells. Both methods showed that the MICs for planktonic cells were less than that for biofilm cells. The BioTimer assay was therefore found to be sensitive, accurate, and reliable, with results in agreement with those from the broth dilution method and SEM.
Plant?es jovens: acolhimento e cuidado por meio da educa??o entre pares para adolescentes e jovens nos Centros de Testagem e Aconselhamento - CTA
Calazans, Gabriela;Kiss, Lígia;Cappellini, Silvana;Sequeira, Daniela;Vieira, Rosangela Mendes;Frana Junior, Ivan;
Saúde e Sociedade , 2006, DOI: 10.1590/S0104-12902006000100004
Abstract: brazil is facing its major youth population of its history. there is an aggravation for the difficult situation met by young brazilians nowadays, because they live in regions submitted to great social vulnerability. young people have specific needs and public policies must be addressed to their particularity, within a participation perspective. an innovative strategy of peer education was developed within the volunteer and counseling testing clinics (vct) from the secretaria municipal da saúde de s?o paulo, intitled plant?o jovem (pj). the pj is integrated by 16 to 24 years old youth that develop welcoming and counseling activities, condom distribution and educative lectures. this article describes the pj from their young agents perspective, aiming to understand how they comprehend their peer-work. three focal groups were developed with the peer-workers from four vct clinics from the peripheric and highly social excluded regions. the peers-workers speeches value the identity shared with their communities' youth in the development of individual and group activities, the emphasis in the practical learning, the focus on the encounter and the other understanding. there were identified some critical points in the development of the proposal: value of techno-scientific information versus the encounter and dialogue centrality within aids prevention; confusion among personal and professional identities, as a peer-education paradox and the confusion between agents and operational technique within peer-education.
Publica??es indexadas geradas a partir de resumos de congressos de angiologia e cirurgia vascular no Brasil
Yoshida, Winston Bonetti;Holmo, Nicole Frana;Corregliano, Gabriela Tieme;Baldon, Karina Marcellino;Silva, Núbia de Souza e;
Jornal Vascular Brasileiro , 2008, DOI: 10.1590/S1677-54492008000400002
Abstract: background: great part of the scientific production presented in congresses is not published. even in developed countries, figures show an expressive difference between presentations and publications. objective: to evaluate the number of published and indexed articles, based on available national and international databases, searching for titles and authors of papers and panels from brazilian vascular surgery congresses held in 2001 and 2003. methods: searches were performed on the abstracts presented on the xxxiv brazilian congress of angiology and vascular surgery, in 2001, and xxxv congress of angiology and vascular surgery in 2003, respectively 541 and 567 presentations. a computerized search was performed using the following databases: scirus, bireme, lilacs, scielo, medline-pubmed, cochrane, google scholar and jornal vascular brasileiro indexes. the articles were classified as national or international and as original or modified. results: twenty-one (3.89%) and 49 (8.64%) articles from the brazilian congresses of vascular surgery of 2001 and 2003 were found, respectively. the average publication rate of papers presented in both congresses was 6.32%. conclusions: the number of publications in this sample show how much research in brazil is put aside. many papers are not published because of lack of priority and tradition in writing, lack of time, effort and encouragement.
Toxicity of azathioprine: why and when? analysis of the prevalence of polymorphism in Joinville, SC, Brazil
Gastal, Gabriela Roncone;Moreira, Simone;Noble, Caroline Furtado;Ferreira, Leslie Ecker;Frana, Paulo Henrique Condeixa de;Pinho, Mauro;
Arquivos de Gastroenterologia , 2012, DOI: 10.1590/S0004-28032012000200007
Abstract: context: the use of thiopurine drugs such as azathioprine and 6-mercaptopurine has become quite common in the treatment of inflammatory bowel disease, transplantation and acute leukemias. despite their effectiveness, these drugs are capable of causing drug-induced toxicity with the risk of death by myelosuppression. it is now known that these complications occur because of genetic polymorphisms of the thiopurinemethyltransferase (tpmt) enzyme, responsible for its metabolism. objective: to assess the prevalence of thiopurine methyltransferase polymorphisms in the population of joinville, sc, brazil. methods: we analyzed the frequency of four main allelic variants of the tpmt gene in 199 blood donors from joinville, from february to april 2010. results: the normal allele ("wild-type") was found in 93.9% of subjects studied. tpmt variants were detected in 12 subjects (6.03%). conclusions: from this study, it was estimated at 6% the risk of toxicity by the administration of azathioprine and 6-mercaptopurine to patients in joinville.
Occult hepatitis B virus infection in patients with chronic liver disease due to hepatitis C virus and hepatocellular carcinoma in Brazil
Branco, Fernanda;Mattos, Angelo Alves de;Coral, Gabriela Perdomo;Vanderborght, Bart;Santos, Diogo Edele;Frana, Paulo;Alexander, Cláudio;
Arquivos de Gastroenterologia , 2007, DOI: 10.1590/S0004-28032007000100013
Abstract: background: the prevalence and consequences of occult hbv infection in patients with chronic liver disease by hcv remain unknown. aims: to evaluate the prevalence of occult hbv infection in a population of hcv-infected patients with hepatocellular carcinoma. methods: the serum samples were tested for hbv dna by nested pcr and liver tissue analysis was carried out using the immunohistochemical technique of 66 hbsag-negative patients: 26 patients with chronic hepatitis by hcv (group 1), 20 with hepatocellular carcinoma related to chronic infection by hcv (group 2) and 20 with negative viral markers for hepatitis b and c (control group). results: occult hbv infection was diagnosed in the liver tissue of 9/46 (19.5%) hcv-infected patients. prevalence of occult b infection was evaluated in the hcv-infected patients with and without hepatocellular carcinoma, and there were seven (77.7%) of whom from group 2, conferring a 35% prevalence of this group. no serum sample was positive for hbv dna in the three groups. conclusion: occult infection b is frequently detected in liver tissue of hcv-infected patients, especially in cases of hepatocellular carcinoma. however large studies are needed to confirm that co-infection could determine a worse progress of chronic liver disease in this population.
Potencial produtivo e composi o das fra es anat micas de quatro híbridos de sorgo sob doses de nitrogênio Production and composition of anatomical fractions of four sorghum hybrids under nitrogen dosages
Régis de Paula Oliveira,Aldi Fernandes de Souza Frana,Eliane Sayuri Miyagi,Alzira Gabriela da Silva
Revista Brasileira de Saúde e Produ??o Animal , 2010,
Abstract: Objetivou-se nesse trabalho avaliar a produ o e composi o das fra es anat micas de quatro híbridos de sorgo sob doses de nitrogênio (N). O delineamento experimental foi em blocos ao acaso em esquema fatorial 4x3 (quatro híbridos de sorgo e três doses de N). Os híbridos de sorgo testados oram os seguintes: 1F 305, 0369 267, 0369 255 e BR 700, enquanto que as doses de N foram 0, 60 e 120kg/ha. Foram determinadas a produ o de matéria natural (PMN), teor de matéria seca (MS), produ o de matéria seca (PMS), produ o total de matéria seca (PTMS), porcentagem de rebrota e composi o das fra es da planta (folhas, colmo e panículas). No primeiro e segundo cortes a PMN e PMS foram maiores na dose de 120kg/ha de N. O teor de MS foi influenciado tanto pelos híbridos quanto pelas doses de N apenas no primeiro corte, mas n o no segundo. O híbrido 0369 255 e a dose de 120 kg/ha de N apresentaram maiores rendimentos de PTMS. O híbrido 1F 305 diferiu dos demais em rela o à propor o de folhas no primeiro corte, enquanto que no segundo, os híbridos 1F 305 e BR 700 apresentaram maior porcentagem de folhas em rela o aos demais. Obteve-se maior propor o de folhas na dose de 120kg/ha de N nos dois cortes. A utiliza o do híbrido 0369 255 adubado com 120kg/ha de N é a melhor recomenda o para obten o de altos rendimentos de sorgo forrageiro. The objective of this study was to evaluate the production and composition of anatomical fractions of four forage sorghum hybrids under three N (nitrogen) dosages. The experimental design was in randomized blocks in a factorial scheme 4x3 (four sorghum hybrids and three N dosages). The sorghum hybrids were the following: 1F 305, 0369 267, 0369 255 and BR 700, and N dosages were 0, 60 and 120 kg/ha. It was determined the NMP (natural matter production), DM (dry matter contents), DMP (dry matter production), TDMP (total dry matter production), regrowth percentage and composition of the anatomical fractions of the plants. In the first and second cuts the N dosage of 120 kg/ha had greatest NMP and DMP. DM contents were influenced by both hybrids and N dosages in the first cut, but not in the second one. The hybrid 0369 255 and N dosage of 120kg/ha had the highest TDMP. The hybrid 1F 305 differed from the others in relation to the proportion of leaves in the first cut. In the second cut the hybrids 1F 305 and BR 700 had the highest proportion of leaves. In both cuts, the N dosage of 120kg/ha had the highest proportion of leaves. Overall, the hybrid 0369 255 fertilized with 120kg/ha of N is the best combination for obtaining high yiel
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