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Search Results: 1 - 10 of 435418 matches for " G. J. "
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Conditioning Strategies Limit Cellular Injury?  [PDF]
J. G. Kingma
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.411065
Abstract: Evaluation of multiorgan protection strategies against ischemic injury in humans is essential to improve quality of life and reduce mortality. Over the past 40 years a host of pharmacologic and non-pharmacologic interventions have been evaluated with the aim of limiting cell damage produced by ischemia-reperfusion injury. Different conditioning strategies, such as remote conditioning, are documented to mitigate ischemic injury in animal and human studies and may have remarkable clinical promise. However, successful clinical application of these interventions remains questionable since protection is known to be compromised in humans with comorbidities either with or without medications. Regardless, ongoing studies continue to examine the underlying mechanisms involved in this endogenous cytoprotective phenomenon to further its successful implementation in the clinical setting. In this review, we examine recent findings in support of remote conditioning stratagems for organ protection and their relevance for translation to clinical use.
Myocardial Infarction: An Overview of STEMI and NSTEMI Physiopathology and Treatment  [PDF]
J. G. Kingma
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.811049
Abstract: Patients with myocardial infarction resulting from acute coronary syndrome are classified by electrocardiographic presentation: 1-acute ST-segment elevation myocardial infarction (STEMI) or 2-non-ST-segment elevation myocardial infarction (NSTEMI). Prompt reperfusion of an infarct-related artery by percutaneous coronary interventions provides some relief of symptoms; long-term prognosis appears to be worse in STEMI compared to NSTEMI patients but clinical findings remain controversial. Reduced myocardial perfusion to the infarct area, caused in part by microvascular obstruction, is a privileged target for diverse pharmacologic or non-pharmacologic interventions (or combinations thereof) to improve clinical outcomes. To date, benefits of both pharmacologic and non-pharmacologic strategies to either limit microvascular obstruction and myocardial injury or improve myocardial perfusion are inconsistent. This review focuses on the physiopathological aspects of myocardial infarction in relation to development of STEMI/NSTEMI and on potential cardioprotective strategies.
A Photonic Model of the Big Bang  [PDF]
J. G. Lartigue
Journal of Modern Physics (JMP) , 2018, DOI: 10.4236/jmp.2018.914157
Abstract: There are two main theories about the origin of the Universe that show similitude with the Genesis writings, though in different verses: the Big Bang1 and the eternal Universe2 (an eventual quantum fluctuation). However, it is possible to partially include the quantum theory in the Big Bang thanks to the nature of photons, to obtain a simple model. It is assumed as the origin of the Universe (space, time, matter and physical laws). A subsequent enormous expansion has been explained by a supposed brief Inflation period, followed up today by a constant adiabatic expansion acceleration. This paper assumes that the Universe is the total Space which contains the Physical Universe covered by an external, empty Space, both expanding at a constant Hubble acceleration ΓH [1]. A Big Bang design is intended by a deduction of the energy and number of primeval photons, from the present CMB value; they would have reacted whether to generate the Physical Universe or to decay till the CMB level. It follows an approach to the Universe expansion work, based on the Hubble field (VH) as well as on Thermo-dynamics. They are calculated: the time and angular momentum required for the Physical Universe to reach the maximum internal velocity c as well as, simultaneously, a c tangential velocity. The Universe luminosity at different periods and the adequate expressions of parameters (Ω, q, k) are revised. It is proposed a modification in the equation of the H(t) parameter and the Ho value. The operator of convective derivative is applied to obtain an equation of continuity for the photonic energy; an adiabatic Jacobian gives similar results. This essay differs from others based on black box radiation, since the Universe has no walls and the photons energy decays continuously.
Multi-Cultural Dynamics on Social Networks under External Random Perturbations  [PDF]
J. Chandra, G. S. Ladde
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2014, DOI: 10.4236/ijcns.2014.76020

This work deals with the development of multi-cultural network-centric dynamic models under the influence of personal intra- and inter-members, as well as community. Each individual member of a society is influenced by her/his interactions with fellow members of the family, neighborhood, region and the universe. The behavior of such complex and highly interacting social networks is characterized by stochastic interconnected dynamical systems. The primary goal is on laying down an investigation of both qualitative and quantitative properties of this network dynamical system. In particular, we would like to determine the regions of conflicts and coexietence as well as to establish the cohesion and stability of emerging states. This is achieved by employing the method of system of differential inequalities and comparison theorems in the context of the energy function. The developed energy function method provides estimates for regions of conflict and cooperation. Moreover, the method also provides sufficient conditions for the community cohesion and stability in a systematic way.

Energy Proficient Reliable Rim Routing Technique for Wireless Heterogeneous Sensor Networks Lifespan Fortification  [PDF]
S. G. Susila, J. Arputhavijayaselvi
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78151
Abstract: Sensor nodes are mainly shielded in the field with limited power supply. In Wireless Sensor Networks, there must be a requirement of an efficient power management, because sensor nodes are deployed in unman attended area with non-rechargeable batteries. Power management can be done by different methods of routing protocols. The proposed Reliable Rim Routing (3R) technique is based on hybrid routing protocol for homogeneous and heterogeneous system for WSNs to ameliorate the performance of the overall system. In 3R, total node deployment area can be multipart in terms of rim and in each rim, and some of the sensor nodes transmit their sensed data directly to base station, and meanwhile remaining sensor nodes send the data through clustering technique to base station like SEP. Proposed 3R technique implementation proves its enhanced WSNs lifetime of 70% energy consumption and 40% throughput compared with existing protocols. Simulation and evaluation results outperformed in terms of energy consumption with increased throughput and network lifetime.
Gerber Shiu Function of Markov Modulated Delayed By-Claim Type Risk Model with Random Incomes  [PDF]
G. Shija, M. J. Jacob
Journal of Mathematical Finance (JMF) , 2016, DOI: 10.4236/jmf.2016.64039
Abstract: This paper analyses the Gerber-Shiu penalty function of a Markov modulated risk model with delayed by-claims and random incomes. It is assumed that each main claim will also generate a by-claim and the occurrence of the by-claim may be delayed depending on associated main claim amount. We derive the system of integral equations satisfied by the penalty function of the model. Further, assuming that the premium size is exponentially distributed, an explicit expression for the Laplace transform of the expected discounted penalty function is derived. For a two-state model with exponential claim sizes, we present the explicit formula for the probability of ruin. Finally we numerically illustrate the influence of the initial capital on the ruin probabilities of the risk model using a specific example. An example for the risk model without any external environment is also provided with numerical results.
Study of the Double Nonlinear Quantum Resonances in Diatomic Molecules  [PDF]
G. V. López, J. G. T. Zanudo
Journal of Modern Physics (JMP) , 2011, DOI: 10.4236/jmp.2011.26057
Abstract: We study the quantum dynamics of diatomic molecule driven by a circularly polarized resonant electric field. We look for a quantum effect due to classical chaos appearing due to the overlapping of nonlinear reso-nances associated to the vibrational and rotational motion. We solve the Schrödinger equation associated with the wave function expanded in term of proper stationary states, |n> |lm> (vibrational angular momentum states). Looking for quantum-classic correspondence, we consider the Liouville dynamics in the two dimensional phase space defined by the coherent-like state of vibrational states. We consider the rela-tionship between the overlapping of the classical resonances and the mixing of the quantum states, and it is found some similarities when the quantum dynamics is pictured in terms of number and phase operators.
Environmental Impact on Surface and Ground Water Pollution from Mining Activities in Ikpeshi, Edo State, Nigeria  [PDF]
G. N. Idris, G. O. Asuen, O. J. Ogundele
International Journal of Geosciences (IJG) , 2014, DOI: 10.4236/ijg.2014.57067

The study was carried out to evaluate the surface and groundwater condition from mining activities in Ikpeshi and its environs in Akoko Edo Local Government Area of Edo State, Nigeria. Twenty water samples were randomly collected and analyzed—one borehole water sample, two hands dug wells, eight river samples and nine quarry pits water samples. The physiochemical, heavy metal and bacteriological analysis of the water sample, as well as the variables were compared with those of the World Health Organization (WHO) standard (2008), United State Environmental Protection Agencies (USEPA) standard (2012) and National Agency For Food, Drug Administration And Control (NAFDAC) in Nigeria to determine their suitability for drinking and domestic purposes. The variables determined are: pH ranges from 7.67 - 8.56 mg/l which is suggestive of neutral to alkaline in character, calcium ranges from 5.12 - 2416 mg/l, turbidity ranges from 1.16 - 15.32 mg/l, total dissolved solid (Tds) ranges from 90 - 366 mg/l and total hardness ranges from 58.65 - 187.37 mg/l, fall within WHO standard, are suggestive of concentration of detergent from soap, calcium, magnesium, suspended solid particles and colloidal matters from some of the water samples. While iron ranges from 0.08 - 0.16 mg/l, potassium ranges from 0.02 - 0.18 mg/l, chloride ranges from 30.03 - 120.13 mg/l, sulphate ranges from 1.03 - 5.36 mg/l, nitrate ranges from 0.01 - 0.23 mg/l, lead ranges from 0 - 0.01 mg/l, Zinc ranges from 0 - 0.08 mg/l, copper ranges from 0 - 0.02 mg/l and magnesium ranges from 1.38 - 6.56 mg/l, fall within standards. Coliform count ranges from 0 - 14 mg/l. The water should be treated before the consumption because of its high concentration of detergent, suspended particles, faecal materials and calcium from the water samples. The quarry pits should be reclaimed and rehabilitate after mining. Alkaline materials should be used to neutralize the rock pile area, dumped site, tailing and mine pit itself to avoid acid generation.

Influence of Forest Management on Acorn Production in the Southeastern Missouri Ozarks: Early Results of a Long-Term Ecosystem Experiment  [PDF]
Matthew G. Olson, Alexander J. Wolf, Randy G. Jensen
Open Journal of Forestry (OJF) , 2015, DOI: 10.4236/ojf.2015.55051
Abstract: Since acorn production is a foundational process of ecosystems dominated by oaks, understanding the impact of forest management practices on acorn production is critical to the sustainable management of oak forests. This investigation addressed the impact of even-aged management (EAM), uneven-aged management (UAM), and no-harvest management (NHM) on the production of mature, sound acorns over an 18-year period (1993-2010) of a long-term, landscape-scale forest management experiment in the Missouri Ozarks. Forest management impacts were investigated at two operational scales: the multi-stand compartment and the stand. We hypothesized that acorn production at both scales would be lower under active management (EAM and UAM) than NHM on these oak-dominated landscapes. Acorn production (acorns/ha/year) of red oaks (mainly black oak (Quercus velutina) and scarlet oak (Q. coccinea)) at the compartment level was lower under active management than NHM during the post-treatment period (1997-2010), but not for white oaks (mainly white oak (Q. alba) and post oak (Q. stellata)), which was largely a result of greater abundance and preferential harvesting of mature red oaks. At the stand scale, acorn production following either intermediate thinning or single-tree selection was comparable to yields observed in untreated stands suggesting that partial overstory removal can be implemented for harvesting timber and other silvicultural objectives without sacrificing acorn production. In many oak-dominated forests, active management will be necessary to mitigate future losses of acorn production driven by oak decline, succession, and climate change, including approaches for sustaining oak recruitment and acorn production.
Is routine blood test of value for evaluating health effects among midwives working with nitrous oxide for pain relief in delivery unit  [PDF]
G. Abascall, M. Johansson, K. J. Jakobsson
Health (Health) , 2011, DOI: 10.4236/health.2011.33031
Abstract: Chronic workplace exposure to high nitrous oxide concentrations has been suggested to potentially be associated to negative health effects caused by the interference with the vitamin B12, methionine synthase pathway. The objective of the present study was to determine if delivery unit work place ambient air nitrous oxide exposure results in detectable hyperhomocysteinemia or signs of macrocytocis in personnel. Blood samples from thirty healthy female fulltime employees, midwives, aged 43 (range 25-62) years were studied. Routine blood test analysed for plasma homocysteine and blood status; haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin concentration, blood status was analysed once before going on vacation and repeated after at least 10 days’ leave, nitrous oxide free period. Median time weighted average was 41 [10 - 547] ppm; 3 out of 11 TWA measurements were above recommended100 ppm limit. Median homocysteine concentrations were 10.7 [5.6 - 16] micromol/L with reference limits of 5.0 – 15 micromol/L. Megaloblastic erythrocytes was not detected in any personnel and no changes in blood status could be detected between before and after a nitrous oxide-free period. Conclusions: One of 3 delivery units’ ambient air quality measures exceed recommended ranges. No signs of routine blood test pathology could be seen in the personnel studied.
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