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Search Results: 1 - 10 of 189854 matches for " G. Drouin "
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From skeletal to non skeletal: The intriguing roles of BMP-9: A literature review  [PDF]
E. Leblanc, G. Drouin, G. Grenier, N. Faucheux, R. Hamdy
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.410A4004
Abstract:

In the well-known superfamily of transforming growth factors beta (TGF-b), bone morphogenetic proteins (BMPs) are one of the most compelling cytokines for their major role in regulation of cell growth and differentiation in both embryonic and adult tissues. This subfamily was first described for its ability of potentiating bone formation, but nowadays, the power of BMPs is well beyond the bone healing scope. Some of the BMPs have been well studied and described in the literature, but the BMP9 is still worthy of attention. It has been shown by many authors that it is the most potent osteogenic BMP. Moreover, it has been described as one of the rare circulating BMPs. In this paper, we will review the recent literature on BMP9 and the different avenues for future research in that field. Our primary scope is to review its relation to bone formation and to elaborate on the available literature on other systems.

Dissemination and implementation of recommendations on hypertension: the Canadian experience
Drouin Denis
Allergy, Asthma & Clinical Immunology , 2010, DOI: 10.1186/1710-1492-6-s4-a10
Abstract:
A two-dimensional continued fractions algorithm with Lagrange and Dirichlet properties
Christian Drouin
Mathematics , 2015,
Abstract: A Lagrange Theorem in dimension 2 is proved, for a particular two-dimensional algorithm, with a very natural geometrical definition. Dirichlet-type properties for the convergence of the algorithm are also proved. These properties procced from a geometrical quality of the algorithm. Some refercences are given to the works of various authors, in the domain of multidimensional continued fractions algorithms.
Analogies et contrastes entre l'expédition d'Egypte et le voyage d'Humboldt et Bonpland
Drouin, Jean-Marc;
História, Ciências, Saúde-Manguinhos , 2001, DOI: 10.1590/S0104-59702001000500003
Abstract: alexandre de humbodlt et aimé bonpland avaient prévu de se joindre aux savants de l'expédition fran?aise en egypte. ayant d? renoncer à ce projet et ayant obtenu l'autorisation du gouvernement espagnol, il réalisèrent leur voyage en amérique latine. la quasi-simultanéité des deux expéditions invite à une comparaison. les points communs ne manquent pas: la production éditoriale au retour, le souci de rendre la science visible, l'importance du repérage spatial et de la collecte naturalistes. cependant, malgré ces ressemblances, le rapport aux pays étudiés est assez contrasté dans ces deux voyages: non seulement à cause du cadre politique mais aussi parce que la conception du travail scientifique est différente. tandis que l'expédition d'egypte réduit seulement la distance du terrain au cabinet sans changer fondamentalement la nature de leur rapport, humboldt transforme le terrain en laboratoire.
Analogies et contrastes entre l'expédition d'Egypte et le voyage d'Humboldt et Bonpland
Drouin Jean-Marc
História, Ciências, Saúde-Manguinhos , 2001,
Abstract: Alexandre de Humbodlt et Aimé Bonpland avaient prévu de se joindre aux savants de l'expédition fran aise en Egypte. Ayant d renoncer à ce projet et ayant obtenu l'autorisation du gouvernement espagnol, il réalisèrent leur voyage en Amérique Latine. La quasi-simultanéité des deux expéditions invite à une comparaison. Les points communs ne manquent pas: la production éditoriale au retour, le souci de rendre la science visible, l'importance du repérage spatial et de la collecte naturalistes. Cependant, malgré ces ressemblances, le rapport aux pays étudiés est assez contrasté dans ces deux voyages: non seulement à cause du cadre politique mais aussi parce que la conception du travail scientifique est différente. Tandis que l'expédition d'Egypte réduit seulement la distance du terrain au cabinet sans changer fondamentalement la nature de leur rapport, Humboldt transforme le terrain en laboratoire.
Influence of a Magnetic Guide Field on Injection in Wakefield Acceleration  [PDF]
Alain Bourdier, Sébastien Rassou, Guillaume Girard, Mathieu Drouin
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.39133
Abstract: The influence of an external static field applied in the direction parallel to the direction of propagation of a high intensity driving laser pulse on the electron trapping in laser wakefield acceleration is explored.
Influence of a Static Magnetic Field on Beam Emittance in Laser Wakefield Acceleration  [PDF]
Mathieu Drouin, Alain Bourdier, Quentin Harry, Sébastien Rassou
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.312249
Abstract:

The enhancement of trapping and the optimization of beam quality are two key issues of Laser Wakefield Acceleration (LWFA). The effect of a homogenous constant magnetic field B0, parallel to the direction of propagation of the pump pulse, is studied in the blowout regime via 2Dx3Dv Particle-In-Cell simulations. Electrons are injected into the wake using a counter-propagating low amplitude laser. Transverse currents are generated at the rim of the bubble, which results in the amplification of the B0 field at the rear of the bubble. Therefore the dynamics of the beam is modified, the main effect is the reduction of the transverse emittance when B0 is raised. Depending on beam loading effects the low energy tail, observed in the non-magnetized case, can be suppressed when B0 is applied, which provides a mono-energetic beam.

Ectopic Gene Conversions in the Genome of Ten Hemiascomycete Yeast Species
Robert T. Morris,Guy Drouin
International Journal of Evolutionary Biology , 2011, DOI: 10.4061/2011/970768
Abstract: We characterized ectopic gene conversions in the genome of ten hemiascomycete yeast species. Of the ten species, three diverged prior to the whole genome duplication (WGD) event present in the yeast lineage and seven diverged after it. We analyzed gene conversions from three separate datasets: paralogs from the three pre-WGD species, paralogs from the seven post-WGD species, and common ohnologs from the seven post-WGD species. Gene conversions have similar lengths and frequency and occur between sequences having similar degrees of divergence, in paralogs from pre- and post-WGD species. However, the sequences of ohnologs are both more divergent and less frequently converted than those of paralogs. This likely reflects the fact that ohnologs are more often found on different chromosomes and are evolving under stronger selective pressures than paralogs. Our results also show that ectopic gene conversions tend to occur more frequently between closely linked genes. They also suggest that the mechanisms responsible for the loss of introns in S. cerevisiae are probably also involved in the gene 3'-end gene conversion bias observed between the paralogs of this species. 1. Introduction The repair of double strand DNA breaks is a critical biological process which maintains genome stability. The primary process whereby double-strand DNA breaks are repaired is via homologous recombination; this process requires the use of a repair template gene which provides a copy of the missing information caused by the double-strand DNA breaks. The repair template can either be an allele (allelic recombination) or a paralog (ectopic recombination). An end product of the homologous recombination pathway is the replacement of the broken part of the damaged gene by a homologous portion of the repair template gene. The damaged gene is therefore converted by the template gene (reviewed in [1]). The factors affecting, and the characteristics of, ectopic and allelic gene conversions have been the focus of many studies, and sequence similarity has been shown to have a profound effect on gene conversion propensity between paralogs. In Escherichia coli, a 2%–4% decrease in sequence similarity between a damaged gene and its repair template can cause a 10- to 40-fold decrease in recombination frequency [2, 3]. Similarly, in Saccharomyces cerevisiae, larger gene conversions are limited to more similar sequences [4]. Chromosomally linked genes are converted more frequently than dispersed genes in Drosophila and humans [5, 6]. In S. cerevisiae, increasing distance between paralogs located on
Influence of a Magnetic Guide Field on Self-Injection in Wakefield Acceleration  [PDF]
Alain Bourdier, Guillaume Girard, Sébastien Rassou, Xavier Davoine, Mathieu Drouin
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.312248
Abstract:

The influence of an external static field applied in the direction of propagation of a high intensity driving laser pulse on the electron trapping in laser wakefield acceleration is explored. It is shown that, in the case of self-injection, the electric charge accelerated can be enhanced in some physical situations.

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?
J. Drouin-Ouellet,R. A. Barker
Stem Cells International , 2012, DOI: 10.1155/2012/926147
Abstract:
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