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Search Results: 1 - 10 of 650131 matches for " Fredson de Paula e;Módolo "
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Effectiveness and safety of endotracheal tube cuffs filled with air versus filled with alkalinized lidocaine: a randomized clinical trial
Navarro, Lais Helena Camacho;Braz, José Reinaldo Cerqueira;Nakamura, Giane;Lima, Rodrigo Moreira e;Silva, Fredson de Paula e;Módolo, Norma Sueli Pinheiro;
Sao Paulo Medical Journal , 2007, DOI: 10.1590/S1516-31802007000600004
Abstract: context and objective: high intracuff pressure in endotracheal tubes (ets) may cause tracheal lesions. the aim of this study was to evaluate the effectiveness and safety of endotracheal tube cuffs filled with air or with alkalinized lidocaine. design and setting: this was a prospective clinical study at the department of anesthesiology, faculdade de medicina de botucatu, universidade estadual paulista. methods: among 50 patients, et cuff pressures were recorded before, 30, 60, 90 and 120 minutes after starting and upon ending nitrous oxide anesthesia. the patients were randomly allocated to two groups: air, with et cuff inflated with air to attain a cuff pressure of 20 cmh2o; and lido, with et cuff filled with 2% lidocaine plus 8.4% sodium bicarbonate to attain the same pressure. et discomfort before tracheal extubation, and sore throat, hoarseness and coughing incidence were studied at the time of discharge from the post-anesthesia care unit, and sore throat and hoarseness were studied 24 hours after anesthesia. results: pressures in lido cuffs were significantly lower than in air cuffs (p < 0.05). tracheal complaints were similar for the two groups, except for lower et discomfort and sore throat incidence after 24 hours and lower systolic arterial pressure at the time of extubation in the lido group (p < 0.05). conclusion: et cuffs filled with alkalinized lidocaine prevented the occurrence of high cuff pressures during n2o anesthesia and reduced et discomfort and postoperative sore throat incidence. thus, alkalinized lidocaine-filled et cuffs seem to be safer than conventional air-filled et cuffs.
Varia o da press o sistólica como indicadora precoce de hipovolemia e guia de reposi o volêmica com solu o hiperosmótica e hiperoncótica no c o
Paiva Filho Odilar de,Braz José Reinaldo Cerqueira,Silva Fredson de Paula e,Pedro Tiago Otávio
Revista Brasileira de Anestesiologia , 2003,
Abstract: JUSTIFICATIVA E OBJETIVOS: Estudos introduziram novo método para avalia o da pré-carga, baseado na análise da varia o da press o sistólica (VPS) durante ventila o artificial. O objetivo desta pesquisa é avaliar se a VPS e sua derivada delta down (ddown) s o indicadoras precoces de hipovolemia e guias de reposi o volêmica com solu o hiperosmótica e hiperoncótica. MéTODO: Doze c es foram submetidos a sangramentos parciais de 5% da volemia até se atingir 20% da volemia (14 ml.kg-1). Antes (controle) e após cada sangramento foram realizadas análises hemodinamicas, respiratórias e sangüíneas. Após, os c es foram submetidos à reposi o com solu o de NaCl a 7,5% em dextran 70 a 3,75% (SHD) (4 ml.kg-1) e novas análises dos atributos estudados foram realizadas aos 5 e 30 minutos após a reposi o. RESULTADOS: A press o arterial média diminuiu durante o sangramento e aumentou após a reposi o, sem retornar aos valores do controle. As press es da artéria pulmonar e do átrio direito (PAD) diminuíram antes e aumentaram após a reposi o para valores semelhantes aos do controle. A press o da artéria pulmonar ocluída (PAPO) diminuiu após o primeiro sangramento e manteve-se em valores abaixo aos do controle, mesmo após a reposi o. O índice cardíaco n o se alterou, mas aumentou após a reposi o, para valores superiores aos do controle. O índice sistólico (IS) diminuiu antes e aumentou após a reposi o, em níveis superiores aos do controle. Os índices de resistência vascular sistêmica (IRVS) e pulmonar (IRVP) n o se alteraram antes, mas diminuíram após a reposi o, com o IRVS em níveis inferiores aos do controle, e o IRVP em níveis semelhantes aos do controle. Os índices de trabalho sistólico dos ventrículos direito (ITSVD) e esquerdo (ITSVE) diminuíram durante o sangramento, mas aumentaram após a reposi o, com o ITSVD em níveis superiores aos do controle e o ITSVE em níveis semelhantes aos do controle. A VPS e ddown aumentaram progressivamente durante o sangramento e diminuíram após a reposi o, mas mantendo-se em valores superiores aos do controle. As maiores correla es de VPS e ddown foram com IS, PAPO, PAD e ITSVE. CONCLUS ES: No c o, nas condi es empregadas, a VPS e sua derivada ddown s o indicadoras precoces de hipovolemia e guias sensíveis de reposi o volêmica com SHD.
Varia??o da press?o sistólica como indicadora precoce de hipovolemia e guia de reposi??o volêmica com solu??o hiperosmótica e hiperoncótica no c?o
Paiva Filho, Odilar de;Braz, José Reinaldo Cerqueira;Silva, Fredson de Paula e;Pedro, Tiago Otávio;Nascimento Júnior, Paulo do;
Revista Brasileira de Anestesiologia , 2003, DOI: 10.1590/S0034-70942003000300007
Abstract: background and objectives: studies have introduced a new method for preload evaluation based on systolic pressure variation analysis (spv) during mechanical ventilation. this research aimed at evaluating whether spv and its delta down derived (ddown) are earlier hypovolemia indicators and guides for volume replacement with hypertonic and hyperoncotic solutions. methods: twelve dogs were submitted to graded hemorrhage of 5% of their volume until reaching 20% of volume (14 ml.kg-1). before (control) and after every hemorrhage, hemodynamic, ventilatory and blood parameters were evaluated. then, dogs were submitted to volume replacement with 7.5% nacl in 3.75% dextran 70 (shd) (4 ml.kg-1), and the parameters were again evaluated 5 and 30 minutes after volume replacement. results: mean blood pressure decreased during hemorrhage and increased after shd infusion, however without returning to baseline values. right atrium (rap) and pulmonary artery pressure (pap) decreased before and increased after volume replacement reaching values similar to baseline. pulmonary capillary wedge pressure (pcwp) decreased after the first hemorrhage and remained below baseline values even after volume replacement. cardiac index has not changed, but increased after shd infusion reaching values above baseline. stroke volume index (svi) decreased before, and increased after volume replacement reaching values above baseline. systemic vascular and pulmonary resistance did not change during hemorrhage, but decreased after volume replacement, with svri remaining below baseline values and svpri in levels similar to baseline. left ventricular stroke work index (lvswi) and right ventricular stroke work index (rvswi) decreased before and increased after shd infusion, with rvswi remaining above baseline values and lvswi in levels similar to baseline. spv and ddown progressively increased during hemorrhage and decreased after volume replacement, however remaining above baseline values. major spv and ddow
A Randomized Controlled Trial Comparing the Efficacy of P6 Acupuncture Plus Ondansetron versus Ondansetron or P6 Acupuncture in the Prevention of Nausea and Vomiting after Bupivacaine-Morphine Spinal Anesthesia  [PDF]
Chang Yen Yin, José Reinaldo Cerqueira Braz, Wei Tzon Hackan Chang Colares, Lídia Raquel de Carvalho, Marília Pinheiro Módolo, Paulo do Nascimento Junior, Norma Sueli Pinheiro Módolo
Open Journal of Anesthesiology (OJAnes) , 2017, DOI: 10.4236/ojanes.2017.78026
Abstract: Objective: To compare P6 acupuncture plus ondansetron with either ondansetron or P6 acupuncture in the prevention of postoperative nausea and vomiting (PONV) in patients submitted to spinal anesthesia. Methods: A randomized controlled trial was performed with 90 patients undergoing orthopedic surgery under spinal anesthesia with bupivacaine, 15 to 17.5 mg, and morphine, 100 μg. They were assigned to one of the three groups: Group Ondansetron (n = 30), patients were given ondansetron, 8 mg intravenously, before spinal block was performed; Group P6 acupuncture (n = 30), patients were subjected to bilateral electrical stimulation of P6 acupoint for 30 minutes before anesthesia; and Group P6 acupuncture plus ondansetron (n = 30), the exact combination of the groups Ondansetron and P6 acupuncture. Results: In the post anesthesia care unit, the incidence of nausea and vomiting ranged from 13.3% to 26.7% and from 6.7% to 13.3%, respectively, with no significant differences among groups (p > 0.05). Ondansetron group had the highest incidence of nausea (73.3%) (p < 0.001) and vomiting (43.3%) (p < 0.001) at the ward from 0 to 24 hours, followed by P6 acupuncture (33.3% and 26.7%) and P6 acupuncture plus ondansetron groups (16.0% and 0%). Conclusion: Preoperative stimulation of P6 acupoint in combination with ondansetron has higher efficacy than either P6 acupoint stimulation or the administration of ondansetron on the prevention of PONV in patients submitted to bupivacaine-morphine spinal anesthesia.
Profile of consumers of milk pasteurized type C and sterilized (UHT) from Janaúba – MG Perfil dos consumidores de leites pasteurizado tipo C e esterilizado (UHT) de Janaúba – MG
Poliana Batista de Aguilar,Fredson Vieira e Silva,Edivania Souza Zeferino,Franklin Delano dos Santos Soares
Semina : Ciências Agrárias , 2012,
Abstract: The objective of this work was to evaluate the consumption of pasteurized type C milk and sterilized (UHT) in the city from Janaúba-MG. The borough had 53.832 inhabitants in the urban area is divided into 58 sectors that were distributed in six samples in accordance population, being chosen randomly. The survey was conducted with 10% of urban population and according to the IBGE of Janaúba the number of habitants per household is 3,84 with respondents 85, 215, 498, 295, 247, and 83 homes respectively, were however interviews conducted in 1561. The consumer profile of milk was obtained by a questionnaire consisting of multiple choice questions related to the consumption of pasteurized and sterilized milk (UHT). The data were compiled and analyzed by using the Chi-Square at 5% probability. In relation to consumption, 91,03% of people interviewed said that consumed milk. Regarding the type of milk, 45% of people interviewed said that consumed pasteurized milk. However, one should bear in mind that 11,06% of these individuals are pasteurized milk donated by the Federal Government program. Of people interviewed, 36,76% said that consumed milk informal. With regard to diseases that are transmitted by milk, 51,65% of people interviewed that consumed sterilized milk said did not know and 61,45% of people interviewed that consumed sterilized milk said that they knew or knew of any disease transmitted by milk. Of people interviewed, 67,65% did not knew any sanitary inspection seal. And 73,48% of people interviewed said that this feature does not influence the time of purchase. The more consumed in the municipality of pasteurized was Janaúba taking into account the milk donated by the Federal Government program, followed by informal and sterilized milks. Objetivou-se com este trabalho avaliar o consumo de leites pasteurizado tipo C e esterilizado (UHT) na cidade de Janaúba-MG. O município possuía 53.832 habitantes na zona urbana sendo dividido em 58 setores que foram distribuídos em 6 amostragens de acordo número de habitantes, sendo escolhidos aleatoriamente. A pesquisa foi realizada com 10% da popula o urbana e de acordo com os dados do IBGE de Janaúba o número de habitantes por casa é de 3,84 sendo entrevistadas 85, 215, 498, 295, 247, e 83 residências respectivamente, entretanto foram realizadas 1561 entrevistas. O perfil do consumidor de leite foi obtido por um questionário constituído por quest es de múltipla escolha referente ao consumo de leites pasteurizado e esterilizado (UHT). Os dados coletados foram compilados e analisados pelo método do Qui-quadrado
Lymphedema in the Mastectomy Postoperative Period: An Integrative Literature Review  [PDF]
Ana Fátima Carvalho Fernandes, Glécya Oliveira Vidal, Camila Brasil Moreira, Tiago Barreto de Castro e Silva, Paula Natasha Rodrigues Valentim, Míria Concei??o Lavinas Santos
Advances in Breast Cancer Research (ABCR) , 2013, DOI: 10.4236/abcr.2013.24025
Abstract:

Aims and Objectives: To analyze the evidence available in the literature on the stages during which upper limb lymphedema after mastectomy occurs. Background: Among the adverse effects of breast cancer treatment, lymphedema is the most prevalent. Design: Integrative literature review. Methods: The Latin American and Caribbean Literature on Health Sciences (Literatura Latino-Americana e do Caribe em Ciências da Saúde—LILACS), PubMed, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used to select the pertinent studies. The identification data for these studies were summarized, and their methodological features and results were extracted. Results: Regarding the time elapsed since surgery, the highest prevalence of lymphedema corresponded to the late postoperative period, and regarding its severity, mild lymphedema was the most prevalent form. The prevalence was also the highest among the women who were subjected to radical mastectomy and radiotherapy. Conclusions: Many women who are undergoing treatment for breast cancer use strategies for the prevention and control of lymphedema of the upper limb following mastectomy. Relevance to Clinical Practice: The findings of the present study might inform future studies aiming to assess strategies that can be started in the immediate and late postoperative stages to detect lymphedema early and prevent the increase of its prevalence during the late postoperative period after mastectomy.

Insecticidal activity of cerrado plant extracts on Rhodnius milesi Carcavallo, Rocha, Galv?o & Jurberg (Hemiptera: Reduviidae), under laboratory conditions
Coelho, André A.M.;Paula, José E. de;Espíndola, Laila S.;
Neotropical Entomology , 2006, DOI: 10.1590/S1519-566X2006000100018
Abstract: chagas' disease is chiefly transmitted by feces of haematophagous bugs (triatominae) that ingested trypanosoma cruzi from blood of infected people or animals. pyrethroids have been the main insecticides used against these insects. however, some populations of insects have shown significant levels of resistance to several pyrethroids, indicating the need of new insecticides for the control of triatomines. insecticidal activity of 24 cerrado plant extracts belonging to five species of four families were assayed on fourth instar nymphs of rhodnius milesi carcavallo, rocha, galv?o & jurberg (hemiptera: reduviidae), under laboratory conditions. for the extract application on triatomines, 50 μg of the extract were topically applied in duplicate on dorsal tergites of ten insects. insects topically treated with acetone, ethanol, as well as insects with no treatment were used as controls. triatomines were observed over a 28-day period. hexanic and ethanolic extracts of simarouba versicolor, guarea kunthiana, guarea guidonia and talauma ovata caused mortality between 20% and 95% of r. milesi in comparison with the controls, which showed no insect mortality. these preliminary data suggest that the ethanolic extract of the root bark of s. versicolor and the hexanic extract of the root of g. guidonia, responsible for a 95% and 75% insect mortality, respectively, should be chemically investigated and monitored through biological assays in order to determine their insecticidal components, that could be used as a molecular model or as biorational compounds for use in insect control programmes.
A regula??o em saúde no Brasil: um breve exame das décadas de 1999 a 2008
Kornis, George E. M.;Braga, Maria Helena;Fagundes, Marise;Paula, Patrícia A. Baumgratz de;
Physis: Revista de Saúde Coletiva , 2011, DOI: 10.1590/S0103-73312011000300017
Abstract: this paper discusses the brazilian experience of health regulation from 1999 to 2008. it aims to understand the interfaces of the regulatory process in health in brazil, particularly the pharmaceutical industry, seeking to identify, historically, the actors and contexts relating to the proceedings. the research was based on literature review and survey of the resolutions of the board of the national health surveillance agency. this survey identified the concentration of these resolutions in the following areas: drugs, human resources and food. regarding drugs, emphasis was placed in three key words: drug registration, practices and substances subject to special control. in addition to a brief history of the evolution of brazilian health surveillance, this paper focused on the regulatory aspects of the national health surveillance agency and its relationship with the pharmaceutical industry. therefore, the text was guided by the desire to answer the following question: is the experience of regulation of the national health surveillance agency able to cope with the adverse scenario created by the world crisis, especially with regard to the pharmaceutical industry? the main conclusion of this study is that despite the many challenges to be overcome by the national sanitary surveillance agency in brazil today, the experience of regulation has made good progress in this decade. a further finding is that these developments were, for the pharmaceutical industry, a protection against the adverse situation created by the global crisis.
Efeito de extratos de plantas do Cerrado em Dipetalogaster maxima (Uhler) (Hemiptera, Reduviidae)
Coelho, André A. M.;de Paula, José E.;Espíndola, Laila S.;
Revista Brasileira de Entomologia , 2009, DOI: 10.1590/S0085-56262009000300020
Abstract: chagas disease, also known as american trypanosomiasis, is chiefly transmitted by faeces of haematophagous bugs (triatominae) that ingested trypanosoma cruzi from blood of infected people or other mammals. pyrethroids have been the main insecticides used against these insects. however, some populations of insects have shown significant levels of resistance to several pyrethroids, indicating the need of new insecticides for the control of triatomines. thus, the insecticidal activity of 83 cerrado plant extracts belonging to 35 species were assayed on first instar nymphs of dipetalogaster maxima (uhler, 1894) (hemiptera, reduviidae), species found in mexico. for the extract application on triatomines, 50 μg of the extract were topically applied in duplicate on dorsal tergites of ten insects. insects topically treated with acetone, ethanol, as well as insects with no treatment were used as controls. triatomines were observed over a 28-day period. the extracts showed no insect mortality, however, fruit hexane and stem bark ethanolic extracts of simarouba versicolor (simaroubaceae) inhibited the rate of ecdysis in d. maxima (40% and 25%, respectively). these preliminary data suggest that this extracts should be chemically investigated and monitored through biological assays in order to determine the components, so that it may be used as a molecular model or as biorational compounds for use in insect control programmes.
Undergraduate Study of Thermal Conductivity of Metals
Ferrari, T. B.;Hara, S. H.;Aziani, J. L.;Rocha, L.;Paula, E. de;Mulato, M.;
Revista Brasileira de Ensino de Física , 2002, DOI: 10.1590/S1806-11172002000300007
Abstract: in this work we analyze an undergraduate experiment used to determine the thermal conductivity of metals (k). we introduce few modifications in order to offer the student the chance to explore dierent models, learning the basic scientiffic method of developing appropriate and improved explanations for each experiment in order to better link theory and empirical results. semi-empirical corrections are introduced in the system in order to check the experimental results according to previously reported k values. as specific cases we use copper [k = 0.92 cal /(°c s cm)], aluminum [k = 0.49 cal /(°c s cm)] and brass [k = 0.26 cal /(°c s cm)] cylinders.
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