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Search Results: 1 - 10 of 168250 matches for " Frank H Morriss Jr "
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Growth in VLBW infants fed predominantly fortified maternal and donor human milk diets: a retrospective cohort study
Tarah T Colaizy, Susan Carlson, Audrey F Saftlas, Frank H Morriss Jr
BMC Pediatrics , 2012, DOI: 10.1186/1471-2431-12-124
Abstract: Retrospective cohort study.171 infants with median gestational age 27 weeks (IQR 25.4, 28.9) and median birthweight 899 g (IQR 724, 1064) were included. 97% of infants received human milk, 51% received > 75% of all enteral intake as human milk. 16% of infants were small-for-gestational age (SGA, < 10th percentile) at birth, and 34% of infants were SGA at discharge. Infants fed >75% human milk had a greater negative change in weight z-score from birth to discharge compared to infants receiving < 75% (?0.6 vs, -0.4, p = 0.03). Protein and caloric supplementation beyond standard human milk fortifier was related to human milk intake (p = 0.04). Among infants receiving > 75% human milk, there was no significant difference in change in weight z-score by milk type (donor ?0.84, maternal ?0.56, mixed ?0.45, p = 0.54). Infants receiving >75% donor milk had higher rates of SGA status at discharge than those fed maternal or mixed milk (56% vs. 35% (maternal), 21% (mixed), p = 0.08).VLBW infants can grow appropriately when fed predominantly fortified human milk. However, VLBW infants fed >75% human milk are at greater risk of poor growth than those fed less human milk. This risk may be highest in those fed predominantly donor human milk.Maternal milk diets have been associated with advantages for extremely low birthweight (ELBW) infants. ELBW infants fed maternal milk have lower rates of necrotizing enterocolitis (NEC) [1-3], the combined outcome of NEC or death [4], late onset sepsis [2,5,6], and have superior neurodevelopmental outcomes compared with those fed preterm formulas [7,8].However, maternal milk diets have also been associated with inferior in-hospital growth when compared with preterm formula. Studies performed prior to the current practice of human milk fortification demonstrated poorer growth in maternal–milk-fed infants compared with those fed formula [9], although neurodevelopmental advantages were associated with human milk intake [7,10]. Results of subsequent
2-Amino-1-(2-carboxylatoethyl)pyrimidin-1-ium monohydrate
Christopher R. Sparrow,Edwin H. Walker Jr,Frank R. Fronczek
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810045332
Abstract: In the title structure, C7H9N3O2·H2O, there are two formula units in the asymmetric unit. The molecule is a zwitterion, containing a quaternary N atom and a deprotonated carboxyl group, with C—O distances in the range 1.256 (2)–1.266 (3) . The two independent molecules form a hydrogen-bonded R22(16) dimer about an approximate inversion center via N—H...O hydrogen bonds, with N...O distances of 2.766 (2) and 2.888 (2) . O—H...O hydrogen bonds involving the water molecules and additional N—H...O hydrogen bonds link these dimers, forming double chains.
3-(2-Acetylanilino)propanoic acid
Christopher R. Sparrow,Edwin H. Walker Jr,Frank R. Fronczek
Acta Crystallographica Section E , 2008, DOI: 10.1107/s1600536808035277
Abstract: The title molecule, C11H13NO3, has its propanoic acid group in an extended conformation, such that the molecule is nearly planar, with a mean deviation of 0.036 [the maxima being 0.106 (1) and 0.110 (1) for the two methylene C atoms]. The NH group forms an intramolecular hydrogen bond with the acetyl group; in the crystal COOH group forms a centrosymmetric hydrogen-bonded dimer.
Serendipitous XMM-Newton Detection of X-ray Emission from the Bipolar Planetary Nebula Hb 5
Rodolfo Montez Jr.,Joel H. Kastner,Bruce Balick,Adam Frank
Physics , 2009, DOI: 10.1088/0004-637X/694/2/1481
Abstract: We report the serendipitous detection by the XMM-Newton X-ray Observatory of an X-ray source at the position of the Type I (He- and N-rich) bipolar planetary nebula Hb 5. The Hb 5 X-ray source appears marginally resolved. While the small number of total counts (~170) and significant off-axis angle of the X-ray source (~7.8') precludes a definitive spatial analysis, the morphology of the X-ray emission appears to trace the brightest features seen in optical images of Hb 5. The X-ray spectrum is indicative of a thermal plasma at a temperature between 2.4 and 3.7 MK and appears to display strong Neon emission. The inferred X-ray luminosity is L_X = 1.5 x 10^32 ergs/s. These results suggest that the detected X-ray emission is dominated by shock-heated gas in the bipolar nebula, although we cannot rule out the presence of a point-like component at the position of the central star. The implications for and correspondence with current models of shock-heated gas in planetary nebulae is discussed.
Field Programmable Gate Array based Front-End Data Acquisition Module for the COSMICi Astroparticle Telescope System
Darryl W. McGowan Jr,David R. Grosby,Michael P. Frank,Sachin Junnarkar,Ray H. O'Neal Jr
Physics , 2012,
Abstract: We describe an FPGA based Front-End Data Acquisition Module (FEDAM) for implementing Time-over-Threshold (ToT) Time-to-Digital conversion (TDC) of pulses obtained from the COSMICi astroparticle telescope detector system photomultiplier tubes. The telescope system consists of a minimum of three scintillation detectors configured to detect particle airshowers likely initiated by Ultra High Energy Cosmic Rays (UHECR). The relative time delay of detection events between the detectors is used to estimate the angle of incidence of the shower. The FEDAM provides time-over-threshold measurements with a resolution of 2 ns. This allows determination of shower direction to an error of 0.035 (cos {\theta})-1 radians where {\theta} is the angle between the baseline axis through a pair of detectors and the plane representing the shower front.
Using to Determine Inhaled Contaminant Volumes and Blower Effectiveness in Several Types of Respirators
Arthur T. Johnson,Frank C. Koh,William H. Scott Jr.,Timothy E. Rehak
Journal of Environmental and Public Health , 2011, DOI: 10.1155/2011/402148
Abstract: This experiment was conducted to determine how much contaminant could be expected to be inhaled when overbreathing several different types of respirators. These included several tight-fitting and loose-fitting powered air-purifying respirators (PAPRs) and one air-purifying respirator (APR). CO2 was used as a tracer gas in the ambient air, and several loose-and tight-fitting respirators were tested on the head form of a breathing machine. CO2 concentration in the exhaled breath was monitored as well as CO2 concentration in the ambient air. This concentration ratio was able to give a measurement of protection factor, not for the respirator necessarily, but for the wearer. Flow rates in the filter/blower inlet and breathing machine outlet were also monitored, so blower effectiveness (defined as the blower contribution to inhaled air) could also be determined. Wearer protection factors were found to range from 1.1 for the Racal AirMate loose-fitting PAPR to infinity for the 3M Hood, 3M Breath-Easy PAPR, and SE 400 breath-responsive PAPR. Inhaled contaminant volumes depended on tidal volume but ranged from 2.02 L to 0 L for the same respirators, respectively. Blower effectiveness was about 1.0 for tight-fitting APRs, 0.18 for the Racal, and greater than 1.0 for two of the loose-fitting PAPRs. With blower effectiveness greater than 1.0, some blower flow during the exhalation phase contributes to the subsequent inhalation. Results from this experiment point to different ways to measure respirator efficacy.
(Z)-1-(2-Hydroxyethyl)-4-(2-methoxybenzylidene)-2-methyl-1H-imidazol-5(4H)-one
Hongyi Wu,Weihua Wang,Edwin H. Walker Jr,Frank R. Fronczek
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536813007770
Abstract: In the title compound, C14H16N2O3, an analog of the chromophore in green fluorescent protein, the methoxyphenyl substituent and the imidazole N adopt a Z conformation with respect to the C=C bond. Aside from the hydroxyethyl group, the molecule is approximately planar, with the five- and six-membered ring planes forming a dihedral angle of 9.3 (1)°. An intramolecular C—H...N contact occurs. In the crystal, O—H...N hydrogen bonds link the molecules, forming chains along the b-axis direction. C—H...O hydrogen bonds are also observed.
The Relation between Canine Hip Dysplasia, Genetic Diversity and Inbreeding by Breed  [PDF]
Frank H. Comhaire
Open Journal of Veterinary Medicine (OJVM) , 2014, DOI: 10.4236/ojvm.2014.45008
Abstract: Objectives: To assess the relation between the prevalence of canine hip dysplasia, inbreeding and genetic diversity by breed. Methods: Retrospective pedigree analysis of 9 breeds based on a reference population of 41,728 individuals, and hip dysplasia assessment in 1745 dogs. Results: Hip dysplasia was less common among breeds with higher coefficient of inbreeding, lower genetic diversity, and highest contribution of one single ancestor to the population. Inbreeding not exceeding 3.25% should be considered safe since it will maintain a sufficiently high genetic diversity within the breed. Clinical Significance: Together with published data on single breeds, the present findings question the general assumption that line-breeding or in-breeding has an adverse effect on the prevalence of hip dysplasia. Hip assessment is indicated in all breeds, but better methods are needed for selecting dogs suitable for reproduction.
Hierarchically-coupled hidden Markov models for learning kinetic rates from single-molecule data
Jan-Willem van de Meent,Jonathan E. Bronson,Frank Wood,Ruben L. Gonzalez Jr.,Chris H. Wiggins
Quantitative Biology , 2013,
Abstract: We address the problem of analyzing sets of noisy time-varying signals that all report on the same process but confound straightforward analyses due to complex inter-signal heterogeneities and measurement artifacts. In particular we consider single-molecule experiments which indirectly measure the distinct steps in a biomolecular process via observations of noisy time-dependent signals such as a fluorescence intensity or bead position. Straightforward hidden Markov model (HMM) analyses attempt to characterize such processes in terms of a set of conformational states, the transitions that can occur between these states, and the associated rates at which those transitions occur; but require ad-hoc post-processing steps to combine multiple signals. Here we develop a hierarchically coupled HMM that allows experimentalists to deal with inter-signal variability in a principled and automatic way. Our approach is a generalized expectation maximization hyperparameter point estimation procedure with variational Bayes at the level of individual time series that learns an single interpretable representation of the overall data generating process.
Gravity and the Standard Model with 130 GeV Truth Quark from D4-D5-E6 Model using 3x3 Octonion Matrices
Frank D. Smith, Jr.
Physics , 1995,
Abstract: The D4-D5-E6 model of gravity and the Standard Model with a 130 GeV truth quark is constructed using 3x3 matrices of octonions. The model has both continuum and lattice versions. The lattice version uses HyperDiamond lattice structure.
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