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Search Results: 1 - 10 of 343290 matches for " Francisco S.;Acencio "
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Experimental pleurodesis induced by antibiotics (macrolides or quinolones)
Teixeira, Lisete R.;Vargas, Francisco S.;Acencio, Milena M. P.;Bumlai, Renan U. M.;Antonangelo, Leila;Marchi, Evaldo;
Clinics , 2006, DOI: 10.1590/S1807-59322006000600012
Abstract: purpose: chemical pleurodesis is a therapeutic tool for the treatment of recurrent pleural effusions, mainly those of neoplastic etiology. in the past, tetracycline was the sclerosant agent of choice in clinical practice, but presently, there is no consensus about an ideal agent. the aim of this study was to evaluate the effectiveness of macrolides (azithromycin and clarithromycin) or quinolones (levofloxacin and gatifloxacin) in inducing experimental pleurodesis in rabbits. method: forty new zealand rabbits randomized into groups of 10 received (at a total volume of 2 ml for each animal) 1 of the 4 drugs by intrapleural injection. after 28 days, the animals were euthanized and the pleural cavity was evaluated macroscopically and microscopically. results: the intensity of the macroscopic adhesions was mild in all groups. on microscopic analysis, minimal pleural fibrosis and inflammation were observed in all animals. conclusion: the macrolides (azithromycin or clarithromycin) and the quinolones (levofloxacin or gatifloxacin) when injected into the normal pleural space of rabbits are not effective in promoting pleurodesis. additional research is required to identify sclerosing agents capable of inducing pleurodesis.
Derrame pleural incomum: metástase pleuropulmonar de tumor neuroectodérmico primitivo
Antonangelo, Leila;Rosa, Adriana Gon?alves;Corá, Aline Pivetta;Acencio, Milena Marques Pagliarelli;Moreira, Luís César;Suso, Francisco Vargas;
Jornal Brasileiro de Pneumologia , 2009, DOI: 10.1590/S1806-37132009000600013
Abstract: primitive neuroectodermal tumor is an invasive neoplasm with neuronal differentiation, which frequently results in metastasis in various organs. we report the case of a patient with primitive neuroectodermal tumor whose primary site was the axilla. the patient presented with metastases in the lung, pleura, bone, iliac muscle and bone marrow. we highlight the uncommon finding in the pleural fluid cytology.
P. Abad,P. Abreu,N. Acencio,S. Acevedo
Revista Colombiana de Cardiología , 2006,
Towards the prediction of essential genes by integration of network topology, cellular localization and biological process information
Marcio L Acencio, Ney Lemke
BMC Bioinformatics , 2009, DOI: 10.1186/1471-2105-10-290
Abstract: We constructed a decision tree-based meta-classifier and trained it on datasets with individual and grouped attributes-network topological features, cellular compartments and biological processes-to generate various predictors of essential genes. We showed that the predictors with better performances are those generated by datasets with integrated attributes. Using the predictor with all attributes, i.e., network topological features, cellular compartments and biological processes, we obtained the best predictor of essential genes that was then used to classify yeast genes with unknown essentiality status. Finally, we generated decision trees by training the J48 algorithm on datasets with all network topological features, cellular localization and biological process information to discover cellular rules for essentiality. We found that the number of protein physical interactions, the nuclear localization of proteins and the number of regulating transcription factors are the most important factors determining gene essentiality.We were able to demonstrate that network topological features, cellular localization and biological process information are reliable predictors of essential genes. Moreover, by constructing decision trees based on these data, we could discover cellular rules governing essentiality.Essential genes are those genes required for growth in a rich medium, i.e., medium containing all nutrients required for growth. The deletion of only one of these genes is sufficient to confer a lethal phenotype on an organism regardless the presence of remaining genes. Therefore, the functions encoded by essential genes are crucial for survival and could be considered as a foundation of life itself [1,2]. The identification of essential genes is important not only for the understanding of the minimal requirements for cellular life, but also for practical purposes. For example, since most antibiotics target essential cellular processes, essential gene products of micr
Controlling the Tax Evasion Dynamics via Majority-Vote Model on Various Topologies  [PDF]
Francisco W. S. Lima
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.21017
Abstract: Within the context of agent-based Monte-Carlo simulations, we study the well-known majority-vote model (MVM) with noise applied to tax evasion on simple square lattices (LS), Honisch-Stauffer (SH), directed and undirected Bara-basi-Albert (BAD, BAU) networks. In to control the fluctuations for tax evasion in the economics model proposed by Zaklan, MVM is applied in the neighborhod of the noise critical qc to evolve the Zaklan model. The Zaklan model had been studied recently using the equilibrium Ising model. Here we show that the Zaklan model is robust because this can be studied using equilibrium dynamics of Ising model also through the nonequilibrium MVM and on various topologies cited above giving the same behavior regardless of dynamic or topology used here.
Tax Evasion Dynamics via Non-Equilibrium Model on Complex Networks  [PDF]
Francisco W. S. Lima
Theoretical Economics Letters (TEL) , 2015, DOI: 10.4236/tel.2015.56089
Abstract: The Zaklan model has become an excellent mechanism to control the tax evasion fluctuations (TEF) in a people- or agent-based community. Initially, the equilibrium Ising model (IM) had been used as a dynamic of temporal evolution of the Zaklan model near the critical point of the IM. On some complex network the IM presents no critical points or well-defined phase transitions. Then, through Monte Carlo simulations we study the recurring problem of the TEF control using the version of non-equilibrium Zaklan model as a control mechanism for TEF via agent-based non-equilibrium majority-vote model (MVM). Here we study the TEF on directed Barabási-Albert (BAD) and Apollonian (ANs) networks where the IM is not applied. We show that the Zaklan model can be also studied using non-equilibrium dynamics through of the non-equilibrium MVM on complex topologies cited above, giving the behavior of the TEF regardless of dynamic or topology used here.
Tax Evasion Dynamics via Non-Equilibrium Model on Directed Small-World Networks  [PDF]
Francisco W. S. Lima
Theoretical Economics Letters (TEL) , 2016, DOI: 10.4236/tel.2016.64086
Abstract: Based on people or agent community, we use the Zaklan model as a mechanism to control the tax evasion fluctuations. Here, we use the non-equilibrium Sánchez-López-Rodríguez model (SLR), i.e. directed Watts-Strogatz networks, as a dynamics of the temporal evolution of the Zaklan model. We simulate the response of tax cheaters to punishment by an auditing authority as well as to the behavior of their neighbors. The higher the punishment is, the smaller is the simulated probability to cheat. This reasonable result shows that our model is qualitatively good.
Eosinophilic pneumonitis induced by aerosol-administered diesel oil and pyrethrum to mice
Garcia,Maria Lúcia B.; Santos,Ubiratan P.; Perini,Adenir; Acencio,Milena M. P.; Lopes,Fernanda D. T. Q. S.; Bueno,Heloisa M. S.; Saldiva,Paulo H. N.; Martins,Milton A.;
Revista Panamericana de Salud Pública , 2009, DOI: 10.1590/S1020-49892009000600008
Abstract: objective: to confirm the episode of eosinophilic pneumonitis that occurred in march 2001 in manaus, amazon, northern brazil, as secondary to home aerosolization with 2% cypermethrin diluted in diesel compared with the more conventional 1% cypermethrin and soybean solution used in prophylaxis of dengue. methods: four groups of swiss mice were kept in polycarbonate cages aerosolized with one of the following solutions: diesel, diesel and cypermethrin, soy oil and cypermethrin, and saline. three and 6 days after exposure, resistance and compliance of the respiratory system and white cell kinetics in peripheral blood and lung tissue were analyzed. results: the group exposed to diesel and cypermethrin showed higher respiratory system resistance (p < 0.001), lower compliance (p = 0.03), and increased eosinophils in blood (p = 0.03) and lung tissue (p = 0.005) compared with the other groups. there was an increase of neutrophils in the blood of all experimental groups on the third day after exposure (p < 0.001). conclusions: we concluded that diesel associated with cypermethrin induced lung hyperresponsiveness in this experimental model and was associated with increased polymorphonuclear cells (eosinophils and neutrophils) in blood and lungs. this effect is strongest on the third day after exposure. these results are similar to the episode that occurred in manaus in 2001 and suggest that diesel plus cypermethrin home aerosolization for arbovirosis prophylaxis should be revised.
Using the ISO 19761 COSMIC Measurement Standard to Reduce “Information Asymmetry” in Software Development Contracts and Enable Greater Competitiveness  [PDF]
Francisco Valdés Souto, Alain Abran
Technology and Investment (TI) , 2013, DOI: 10.4236/ti.2013.44031

In most economic transactions involving software development projects, differences in the amount and quality of information possessed by economic agents (i.e. producers and customers) can lead to significant market inefficiencies. This paper describes the way the information derived from the functional size of software measured using the ISO 19761 COSMIC measurement standard that can help reduce information asymmetry in software development transactions, and lead to increased competitiveness in the software industry.

Sheep and Goat Production in Portugal: A Dynamic View  [PDF]
Manuel Luís Tiberio, Francisco Diniz
Modern Economy (ME) , 2014, DOI: 10.4236/me.2014.56066

Sheep production is probably one of the oldest productions in the world. In early years this animal was considered as a domestic and productive one, since it provided families with milk, meat and wool. Besides providing all these products, the animals were not difficult to grow. They fed on many different floras that others would leave so their owners started to walk great distances with them to get the best grazing spots in winter and in summer. They called this transhumance. But in nowadays, animal feed became easier to get to. It was no longer necessary to move all the animals to pastures hundreds of kilometers away, and producers started going for shorter distances. Production also got more intensive, although sheep production was always considered to be more extensive rather than intensive. With this revision we intend to go over all the statistics concerning this production in Portugal and compare it in different years, to establish a correlation between them. Although sheep production is made entirely with autochthonous breeds and these are milk and meat production oriented, the meat production has a higher relevance in the sector. So it was necessary to make a more thorough approach to this production. There is also an interest in new and emergent ways of production which we discuss at the end of this revision, along with a small global analysis.

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